| 1. |
- Bombarda, F., et al.
(författare)
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Runaway electron beam control
- 2019
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 61:1
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Tidskriftsartikel (refereegranskat)
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| 2. |
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- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:1
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Forskningsöversikt (refereegranskat)
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| 20. |
- Abel, I, et al.
(författare)
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Overview of the JET results with the ITER-like wall
- 2013
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 53:10, s. 104002-
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Tidskriftsartikel (refereegranskat)abstract
- Following the completion in May 2011 of the shutdown for the installation of the beryllium wall and the tungsten divertor, the first set of JET campaigns have addressed the investigation of the retention properties and the development of operational scenarios with the new plasma-facing materials. The large reduction in the carbon content (more than a factor ten) led to a much lower Z(eff) (1.2-1.4) during L- and H-mode plasmas, and radiation during the burn-through phase of the plasma initiation with the consequence that breakdown failures are almost absent. Gas balance experiments have shown that the fuel retention rate with the new wall is substantially reduced with respect to the C wall. The re-establishment of the baseline H-mode and hybrid scenarios compatible with the new wall has required an optimization of the control of metallic impurity sources and heat loads. Stable type-I ELMy H-mode regimes with H-98,H-y2 close to 1 and beta(N) similar to 1.6 have been achieved using gas injection. ELM frequency is a key factor for the control of the metallic impurity accumulation. Pedestal temperatures tend to be lower with the new wall, leading to reduced confinement, but nitrogen seeding restores high pedestal temperatures and confinement. Compared with the carbon wall, major disruptions with the new wall show a lower radiated power and a slower current quench. The higher heat loads on Be wall plasma-facing components due to lower radiation made the routine use of massive gas injection for disruption mitigation essential.
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| 21. |
- Sheena, B. S., et al.
(författare)
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Global, regional, and national burden of hepatitis B, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- 2022
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Ingår i: Lancet Gastroenterology & Hepatology. - : Elsevier BV. - 2468-1253. ; 7:9, s. 796-829
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Tidskriftsartikel (refereegranskat)abstract
- Background Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-ofsample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4 center dot 1% (95% uncertainty interval [UI] 3 center dot 7 to 4 center dot 5), corresponding to 316 million (284 to 351) infected people. There was a 31 center dot 3% (29 center dot 0 to 33 center dot 9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76 center dot 8% (76 center dot 2 to 77 center dot 5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 000 global deaths (487 000 to 630 000) in 2019. The number of HBV-related deaths increased between 1990 and 2019 (by 5 center dot 9% [-5 center dot 6 to 19 center dot 2]) and between 2015 and 2019 (by 2 center dot 9% [-5 center dot 9 to 11 center dot 3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. As of 2019, 68 of 194 countries had already achieved the 2030 target proposed in WHO Interim Guidance of an all-age HBV-related death rate of four per 100 000. Interpretation The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years, but few countries had met the WHO-GHSS interim targets for deaths and new cases. Progress according to all indicators must be accelerated to meet 2030 targets, and there are marked disparities in burden and progress across the world. HBV interventions, such as vaccination, testing, and treatment, must be strategically supported and scaled up to achieve elimination.
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| 22. |
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- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:9
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Tidskriftsartikel (refereegranskat)
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| 23. |
- Abbafati, Cristiana, et al.
(författare)
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- 2020
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Tidskriftsartikel (refereegranskat)
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| 24. |
- Litaudon, X., et al.
(författare)
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14 MeV calibration of JET neutron detectors-phase 1: Calibration and characterization of the neutron source
- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:2
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Tidskriftsartikel (refereegranskat)abstract
- In view of the planned DT operations at JET, a calibration of the JET neutron monitors at 14 MeV neutron energy is needed using a 14 MeV neutron generator deployed inside the vacuum vessel by the JET remote handling system. The target accuracy of this calibration is 10% as also required by ITER, where a precise neutron yield measurement is important, e.g. for tritium accountancy. To achieve this accuracy, the 14 MeV neutron generator selected as the calibration source has been fully characterised and calibrated prior to the in-vessel calibration of the JET monitors. This paper describes the measurements performed using different types of neutron detectors, spectrometers, calibrated long counters and activation foils which allowed us to obtain the neutron emission rate and the anisotropy of the neutron generator, i.e.The neutron flux and energy spectrum dependence on emission angle, and to derive the absolute emission rate in 4π sr. The use of high resolution diamond spectrometers made it possible to resolve the complex features of the neutron energy spectra resulting from the mixed D/T beam ions reacting with the D/T nuclei present in the neutron generator target. As the neutron generator is not a stable neutron source, several monitoring detectors were attached to it by means of an ad hoc mechanical structure to continuously monitor the neutron emission rate during the in-vessel calibration. These monitoring detectors, two diamond diodes and activation foils, have been calibrated in terms of neutrons/counts within ± 5% total uncertainty. A neutron source routine has been developed, able to produce the neutron spectra resulting from all possible reactions occurring with the D/T ions in the beam impinging on the Ti D/T target. The neutron energy spectra calculated by combining the source routine with a MCNP model of the neutron generator have been validated by the measurements. These numerical tools will be key in analysing the results from the in-vessel calibration and to derive the response of the JET neutron detectors to DT plasma neutrons starting from the response to the generator neutrons, and taking into account all the calibration circumstances.
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| 25. |
- Martin, P., et al.
(författare)
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Overview of the RFX fusion science program
- 2011
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 51:9, s. 094023-
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Tidskriftsartikel (refereegranskat)abstract
- This paper summarizes the main achievements of the RFX fusion science program in the period between the 2008 and 2010 IAEA Fusion Energy Conferences. RFX-mod is the largest reversed field pinch in the world, equipped with a system of 192 coils for active control of MHD stability. The discovery and understanding of helical states with electron internal transport barriers and core electron temperature >1.5 keV significantly advances the perspectives of the configuration. Optimized experiments with plasma current up to 1.8 MA have been realized, confirming positive scaling. The first evidence of edge transport barriers is presented. Progress has been made also in the control of first-wall properties and of density profiles, with initial first-wall lithization experiments. Micro-turbulence mechanisms such as ion temperature gradient and micro-tearing are discussed in the framework of understanding gradient-driven transport in low magnetic chaos helical regimes. Both tearing mode and resistive wall mode active control have been optimized and experimental data have been used to benchmark numerical codes. The RFX programme also provides important results for the fusion community and in particular for tokamaks and stellarators on feedback control of MHD stability and on three-dimensional physics. On the latter topic, the result of the application of stellarator codes to describe three-dimensional reversed field pinch physics will be presented.
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| 26. |
- Salewski, M., et al.
(författare)
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Diagnostic of fast-ion energy spectra and densities in magnetized plasmas
- 2019
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Ingår i: Journal of Instrumentation. - : Institute of Physics Publishing (IOPP). - 1748-0221. ; 14
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Tidskriftsartikel (refereegranskat)abstract
- The measurement of the energy spectra and densities of alpha-particles and other fast ions are part of the ITER measurement requirements, highlighting the importance of energy-resolved energetic-particle measurements for the mission of ITER. However, it has been found in recent years that the velocity-space interrogation regions of the foreseen energetic-particle diagnostics do not allow these measurements directly. We will demonstrate this for gamma-ray spectroscopy (GRS), collective Thomson scattering (CTS), neutron emission spectroscopy and fast-ion D-alpha spectroscopy by invoking energy and momentum conservation in each case, highlighting analogies and differences between the different diagnostic velocity-space sensitivities. Nevertheless, energy spectra and densities can be inferred by velocity-space tomography which we demonstrate using measurements at JET and ASDEX Upgrade. The measured energy spectra agree well with corresponding simulations. At ITER, alpha-particle energy spectra and densities can be inferred for energies larger than 1.7 MeV by velocity-space tomography based on GRS and CTS. Further, assuming isotropy of the alpha-particles in velocity space, their energy spectra and densities can be inferred by 1D inversion of spectral single-detector measurements down to about 300 keV by CTS. The alpha-particle density can also be found by fitting a model to the CTS measurements assuming the alpha-particle distribution to be an isotropic slowing-down distribution.
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| 27. |
- Batistoni, P., et al.
(författare)
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Benchmark experiments on neutron streaming through JET Torus Hall penetrations
- 2015
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Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 55:5
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Tidskriftsartikel (refereegranskat)abstract
- Neutronics experiments are performed at JET for validating in a real fusion environment the neutronics codes and nuclear data applied in ITER nuclear analyses. In particular, the neutron fluence through the penetrations of the JET torus hall is measured and compared with calculations to assess the capability of state-of-art numerical tools to correctly predict the radiation streaming in the ITER biological shield penetrations up to large distances from the neutron source, in large and complex geometries. Neutron streaming experiments started in 2012 when several hundreds of very sensitive thermo-luminescence detectors (TLDs), enriched to different levels in (LiF)-Li-6/(LiF)-Li-7, were used to measure the neutron and gamma dose separately. Lessons learnt from this first experiment led to significant improvements in the experimental arrangements to reduce the effects due to directional neutron source and self-shielding of TLDs. Here we report the results of measurements performed during the 2013-2014 JET campaign. Data from new positions, at further locations in the South West labyrinth and down to the Torus Hall basement through the air duct chimney, were obtained up to about a 40m distance from the plasma neutron source. In order to avoid interference between TLDs due to self-shielding effects, only TLDs containing natural Lithium and 99.97% Li-7 were used. All TLDs were located in the centre of large polyethylene (PE) moderators, with Li-nat and Li-7 crystals evenly arranged within two PE containers, one in horizontal and the other in vertical orientation, to investigate the shadowing effect in the directional neutron field. All TLDs were calibrated in the quantities of air kerma and neutron fluence. This improved experimental arrangement led to reduced statistical spread in the experimental data. The Monte Carlo N-Particle (MCNP) code was used to calculate the air kerma due to neutrons and the neutron fluence at detector positions, using a JET model validated up to the magnetic limbs. JET biological shield and penetrations, the PE moderators and TLDs were modelled in detail. Different tallying methods were used in the calculations, which are routinely used in ITER nuclear analyses: the mesh tally and the track length estimator with multiple steps calculations using the surface source write/read capability available in MCNP. In both cases, the calculated neutron fluence (C) was compared to the measured fluence (E) and hence C/E comparisons have been obtained and are discussed. These results provide a validation of neutronics numerical tools, codes and nuclear data, used for ITER design.
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| 28. |
- Cawthon, Peggy M, et al.
(författare)
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What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium.
- 2021
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Ingår i: The journals of gerontology. Series A, Biological sciences and medical sciences. - : Oxford University Press (OUP). - 1758-535X .- 1079-5006. ; 76:10
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Tidskriftsartikel (refereegranskat)abstract
- Cut-points to define slow walking speed have largely been derived from expert opinion.Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not.Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but <0.75 m/s); and 421 (8.3%) as "slow" (walking speed <0.62 m/s). Among 13 589 men, CART analysis identified 3 cut-points, classifying 10 001 (73.6%) with walking speed ≥1.00 m/s ("very fast"); 2901 (21.3%) as "fast" (walking speed ≥0.74 m/s but <1.00 m/s); 497 (3.7%) as "intermediate" (walking speed ≥0.57 m/s but <0.74 m/s); and 190 (1.4%) as "slow" (walking speed <0.57 m/s). Prevalence of self-reported mobility limitation was lowest in the "fast" or "very fast" (11% for men and 19% for women) and highest in the "slow" (60.5% in men and 71.0% in women). Rounding the 2 slower cut-points to 0.60 m/s and 0.75 m/s reclassified very few participants.Cut-points in walking speed of approximately 0.60 m/s and 0.75 m/s discriminate those with self-reported mobility limitation from those without.
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| 29. |
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| 30. |
- Puiatti, M. E., et al.
(författare)
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Helical equilibria and magnetic structures in the reversed field pinch and analogies to the tokamak and stellarator
- 2009
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 0741-3335 .- 1361-6587. ; 51:12, s. 124031-
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Tidskriftsartikel (refereegranskat)abstract
- The reversed field pinch configuration is characterized by the presence of magnetic structures both in the core and at the edge: in the core, at high plasma current the spontaneous development of a helical structure is accompanied by the appearance of internal electron transport barriers; at the edge strong pressure gradients, identifying an edge transport barrier, are observed too, related to the position of the field reversal surface. The aim of this paper is the experimental characterization of both the internal and edge transport barriers in relation to the magnetic topology, discussing possible analogies and differences with other confinement schemes.
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| 31. |
- Puiatti, M. E., et al.
(författare)
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Internal and external electron transport barriers in the RFX-mod reversed field pinch
- 2011
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 51:7, s. 073038-
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Tidskriftsartikel (refereegranskat)abstract
- An interesting result of magnetic chaos reduction in RFX-mod high current discharges is the development of strong electron transport barriers. An internal heat and particle transport barrier is formed when a bifurcation process changes the magnetic configuration into a helical equilibrium and chaos reduction follows, together with the formation of a null in the q shear. Strong temperature gradients develop, corresponding to a decreased thermal and particle transport. Turbulence analysis shows that the large electron temperature gradients are limited by the onset of micro-tearing modes, in addition to residual magnetic chaos. A new type of electron transport barrier with strong temperature gradients develops more externally (r/a = 0.8) accompanied by a 30% improvement of the global confinement time. The mechanism responsible for the formation of such a barrier is still unknown but it is likely associated with a local reduction of magnetic chaos. These external barriers develop primarily in situations of well-conditioned walls so that they might be regarded as attempts towards an L-H transition. Both types of barriers occur in high-current low-collisionality regimes. Analogies with tokamak and stellarators are discussed.
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| 32. |
- Salewski, M., et al.
(författare)
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Bayesian Integrated Data Analysis of Fast-Ion Measurements by Velocity-Space Tomography
- 2018
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Ingår i: Fusion science and technology. - : TAYLOR & FRANCIS INC. - 1536-1055 .- 1943-7641. ; 74:1-2, s. 23-36
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Tidskriftsartikel (refereegranskat)abstract
- Bayesian integrated data analysis combines measurements from different diagnostics to jointly measure plasma parameters of interest such as temperatures, densities, and drift velocities. Integrated data analysis of fast-ion measurements has long been hampered by the complexity of the strongly non-Maxwellian fast-ion distribution functions. This has recently been overcome by velocity-space tomography. In this method two-dimensional images of the velocity distribution functions consisting of a few hundreds or thousands of pixels are reconstructed using the available fast-ion measurements. Here we present an overview and current status of this emerging technique at the ASDEX Upgrade tokamak and the JET toamak based on fast-ion D-alpha spectroscopy, collective Thomson scattering, gamma-ray and neutron emission spectrometry, and neutral particle analyzers. We discuss Tikhonov regularization within the Bayesian framework. The implementation for different types of diagnostics as well as the uncertainties are discussed, and we highlight the importance of integrated data analysis of all available detectors.
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| 33. |
- Terranova, D., et al.
(författare)
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A 3D approach to equilibrium, stability and transport studies in RFX-mod improved regimes
- 2010
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 0741-3335 .- 1361-6587. ; 52:12, s. 124023-
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Tidskriftsartikel (refereegranskat)abstract
- The full three-dimensional (3D) approach is now becoming an important issue for all magnetic confinement configurations. It is a necessary condition for the stellarator but also the tokamak and the reversed field pinch (RFP) now cannot be completely described in an axisymmetric framework. For the RFP the observation of self-sustained helical configurations with improved plasma performances require a better description in order to assess a new view on this configuration. In this new framework plasma configuration studies for RFX-mod have been considered both with tools developed for the RFP as well as considering codes originally developed for the stellarator and adapted to the RFP. These helical states are reached through a transition to a very low/reversed shear configuration leading to internal electron transport barriers. These states are interrupted by MHD reconnection events and the large Te gradients at the barriers indicate that both current and pressure driven modes are to be considered. Furthermore the typically flat Te profiles in the helical core have raised the issue of the role of electrostatic and electromagnetic turbulence in these reduced chaos regions, so that a stability analysis in the correct 3D geometry is required to address an optimization of the plasma setup. In this viewtheVMECcode proved to be an effectiveway to obtain helical equilibria to be studied in terms of stability and transport with a suite of well tested codes. In this work, the equilibrium reconstruction technique as well as the experimental evidence of 3D effects and their first interpretation in terms of stability and transport are presented using both RFP and stellarator tools.
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| 34. |
- Vasilopoulou, T., et al.
(författare)
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Neutron streaming along ducts and labyrinths at the JET biological shielding : Effect of concrete composition
- 2015
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Ingår i: Radiation Physics and Chemistry. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0969-806X .- 1879-0895. ; 116, s. 359-364
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Tidskriftsartikel (refereegranskat)abstract
- Experiments and Monte Carlo simulations were performed at the Joint European Torus (JET) in order to validate the computational tools and methods applied for neutron streaming calculations through penetrations in the JET Hall biological shielding. In the present work the sensitivity of the simulations on the hydrogen and boron content in concrete shielding was investigated. MCNP code was used to simulate neutron streaming along the JET Hall personnel entrance labyrinth for deuterium-deuterium and deuterium-tritium plasma sources for different concrete wall compositions. Neutron fluence and ambient dose equivalent along the labyrinth were calculated. Simulation results for the "as built" JET concrete composition were compared against measurements performed using thermoluminescence detectors. This study contributes to the optimization of the radiation shielding of JET and, furthermore, provides information from JET experience that may assist in optimizing and validating the radiation shielding design methodology used in its successor fusion devices ITER and DEMO.
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| 35. |
- Weisen, H., et al.
(författare)
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The 'neutron deficit' in the JET tokamak
- 2017
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 57:7
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Tidskriftsartikel (refereegranskat)abstract
- The measured D-D neutron rate of neutral beam heated JET baseline and hybrid H-modes in deuterium is found to be between approximately 50% and 100% of the neutron rate expected from the TRANSP code, depending on the plasma parameters. A number of candidate explanations for the shortfall, such as fuel dilution, errors in beam penetration and effectively available beam power have been excluded. As the neutron rate in JET is dominated by beamplasma interactions, the ` neutron deficit' may be caused by a yet unidentified form of fast particle redistribution. Modelling, which assumes fast particle transport to be responsible for the deficit, indicates that such redistribution would have to happen at time scales faster than both the slowing down time and the energy confinement time. Sawteeth and edge localised modes are found to make no significant contribution to the deficit. There is also no obvious correlation with magnetohydrodynamic activity measured using magnetic probes at the tokamak vessel walls. Modelling of fast particle orbits in the 3D fields of neoclassical tearing modes shows that realistically sized islands can only contribute a few percent to the deficit. In view of these results it appears unlikely that the neutron deficit results from a single physical process in the plasma.
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| 36. |
- Withers, Sarah B., et al.
(författare)
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Eosinophils are key regulators of perivascular adipose tissue and vascular functionality
- 2017
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- Obesity impairs the relaxant capacity of adipose tissue surrounding the vasculature (PVAT) and has been implicated in resultant obesity-related hypertension and impaired glucose intolerance. Resident immune cells are thought to regulate adipocyte activity. We investigated the role of eosinophils in mediating normal PVAT function. Healthy PVAT elicits an anti-contractile effect, which was lost in mice deficient in eosinophils, mimicking the obese phenotype, and was restored upon eosinophil reconstitution. Ex vivo studies demonstrated that the loss of PVAT function was due to reduced bioavailability of adiponectin and adipocyte-derived nitric oxide, which was restored after eosinophil reconstitution. Mechanistic studies demonstrated that adiponectin and nitric oxide are released after activation of adipocyte-expressed β3 adrenoceptors by catecholamines, and identified eosinophils as a novel source of these mediators. We conclude that adipose tissue eosinophils play a key role in the regulation of normal PVAT anti-contractile function.
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| 37. |
- Baiocchi, B., et al.
(författare)
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Transport analysis and modelling of the evolution of hollow density profiles plasmas in JET and implication for ITER
- 2015
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Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 55:12
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Tidskriftsartikel (refereegranskat)abstract
- The density evolution during the transient phase just after the L-H transition is investigated using theoretical transport models. Cases characterized by core densities which evolve in longer timescales than the edge densities, leading to hollow density profiles (R/L-n = -R del n/n < 0) are modelled. This density evolution is particularly interesting because it has been shown to be beneficial in the view of the access to burning plasma conditions in ITER (Loarte et al 2013 Nucl. Fusion 53 083031). Self-consistent simulations of the JET discharge 79676 of the density-only, and of the density and the temperatures are carried out using a quasilinear gyrokinetic code, QuaLiKiz (Bourdelle et al 2007 Phys. Plasmas 14 112501), coupled with a transport code CRONOS (Artaud et al 2010 Nucl. Fusion 50 043001). The slow evolution of the hollow density, associated with the self-consistently calculated hollow NBI particle deposition, is well reproduced in the plasma core. Indeed, QuaLiKiz is shown to reproduce nonlinear gyrokinetic heat and particle fluxes well for both positive and negative R/L-n. That gives a theoretical and general basis for the persistence of the hollowness, laying the groundwork for the extrapolation to ITER.
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| 38. |
- Baiocchi, B., et al.
(författare)
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Turbulent transport analysis of JET H-mode and hybrid plasmas using QuaLiKiz and Trapped Gyro Landau Fluid
- 2015
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 0741-3335 .- 1361-6587. ; 57:3
-
Tidskriftsartikel (refereegranskat)abstract
- The physical transport processes at the basis of JET typical inductive H-mode scenarios and advanced hybrid regimes, with improved thermal confinement, are analyzed by means of some of the newest and more sophisticated quasi-linear transport models: trapped gyro Landau fluid (TGLF) and QuaLiKiz. The temporal evolution of JET pulses is modelled by CRONOS where the turbulent transport is modelled by either QuaLiKiz or TGLF. Both are first principle models with a more comprehensive physics than the models previously developed and therefore allow the analysis of the physics at the basis of the investigated scenarios. For H-modes, ion temperature gradient (ITG) modes are found to be dominant and the transport models are able to properly reproduce temperature profiles in self-consistent simulations. However, for hybrid regimes, in addition to ITG trapped electron modes (TEM) are also found to be important and different physical mechanisms for turbulence reduction play a decisive role. Whereas E x B flow shear and plasma geometry have a limited impact on turbulence, the presence of a large population of fast ions, quite important in low density regimes, can stabilize core turbulence mainly when the electromagnetic effects are taken into account. The TGLF transport model properly captures these mechanisms and correctly reproduces temperatures.
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| 39. |
- Bradwell, Hannah Louise, et al.
(författare)
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Staff perceptions towards virtual reality-motivated treadmill exercise for care home residents: a qualitative feedback study with key stakeholders and follow-up interview with technology developer
- 2023
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Ingår i: BMJ Open. - 2044-6055. ; 13:11
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Tidskriftsartikel (refereegranskat)abstract
- Objectives Health and care resources are under increasing pressure, partly due to the ageing population. Physical activity supports healthy ageing, but motivating exercise is challenging. We aimed to explore staff perceptions towards a virtual reality (VR) omnidirectional treadmill (MOTUS), aimed at increasing physical activity for older adult care home residents. Design Interactive workshops and qualitative evaluation. Settings Eight interactive workshops were held at six care homes and two university sites across Cornwall, England, from September to November 2021. Participants Forty-four staff participated, including care home, supported living, clinical care and compliance managers, carers, activity coordinators, occupational therapists and physiotherapists. Interventions Participants tried the VR treadmill system, followed by focus groups exploring device design, potential usefulness or barriers for care home residents. Focus groups were audio-recorded, transcribed verbatim and thematically analysed. We subsequently conducted a follow-up interview with the technology developer (September 2022) to explore the feedback impact. Results The analysis produced seven key themes: anticipated benefits, acceptability, concerns of use, concerns of negative effects, suitability/unsuitability, improvements and current design. Participants were generally positive towards VR to motivate care home residents' physical activity and noted several potential benefits (increased exercise, stimulation, social interaction and rehabilitation). Despite the reported potential, staff had safety concerns for frail older residents due to their standing position. Participants suggested design improvements to enhance safety, usability and accessibility. Feedback to the designers resulted in the development of a new seated VR treadmill to address concerns about falls while maintaining motivation to exercise. The follow-up developer interview identified significant value in academia-industry collaboration. Conclusion The use of VR-motivated exercise holds the potential to increase exercise, encourage reminiscence and promote meaningful activity for care home residents. Staff concerns resulted in a redesigned seated treadmill for those too frail to use the standing version. This novel study demonstrates the importance of stakeholder feedback in product design.
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| 40. |
- Giacomelli, L., et al.
(författare)
-
Neutron emission spectroscopy of D plasmas at JET with a compact liquid scintillating neutron spectrometer
- 2018
-
Ingår i: Review of Scientific Instruments. - : AMER INST PHYSICS. - 0034-6748 .- 1089-7623. ; 89:10
-
Tidskriftsartikel (refereegranskat)abstract
- Neutron emission spectroscopy is a diagnostic technique that allows for energy measurements of neutrons born in nuclear reactions. The JET tokamak fusion experiment (Culham, UK) has a special role in this respect as advanced spectrometers for 2.5 MeV and 14 MeV neutrons have been developed here for the first time for measurements of the neutron emission spectrum from D and DT plasmas with unprecedented accuracy. Twin liquid scintillating neutron spectrometers were built and calibrated at the Physikalisch-Technische Bundesanstalt (PTB) (Braunschweig, Germany) and installed on JET in the recent years with tangential-equatorial (KM12) and vertical-radial (KM13) view lines, with the latter only recently operational. This article reports on the performance of KM12 and on the development of the data analysis methods in order to extract physics information upon D ions kinematics in JET auxiliary-heated D plasmas from 2.5 MeV neutron measurements. The comparison of these results with the correspondents from other JET neutron spectrometers is also presented: their agreement allows for JET unique capability of multi-lines of sight neutron spectroscopy and for benchmarking other 14 MeV neutron spectrometers installed on the same lines of sight in preparation for the DT experimental campaign at JET.
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| 41. |
- Lomanowski, B. A., et al.
(författare)
-
Inferring divertor plasma properties from hydrogen Balmer and Paschen series spectroscopy in JET-ILW
- 2015
-
Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 55:12
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Tidskriftsartikel (refereegranskat)abstract
- A parametrised spectral line profile model is formulated to investigate the diagnostic scope for recovering plasma parameters from hydrogenic Balmer and Paschen series spectroscopy in the context of JET-ILW divertor plasmas. The separate treatment of Zeeman and Stark contributions in the line model is tested against the PPP-B code which accounts for their combined influence on the spectral line shape. The proposed simplified model does not fully reproduce the Stark-Zeeman features for the alpha and beta transitions, but good agreement is observed in the line width and wing profiles, especially for n > 5. The line model has been applied to infer radial density profiles in the JET-ILW divertor with generally good agreement between the D 5 -> 2, 5 -> 3, 6 -> 2, 7 -> 2 and 9 -> 2 lines for high recycling and detached conditions. In an L-mode detached plasma pulse the Langmuir probe measurements typically underestimated the density by a factor 2-3 and overestimated the electron temperature by a factor of 5-10 compared to spectroscopically derived values. The line model is further used to generate synthetic high-resolution spectra for low-n transitions to assess the potential for parameter recovery using a multi-parametric fitting technique. In cases with 4 parameter fits with a single Maxwellian neutral temperature component the D 4 -> 3 line yields the best results with parameter estimates within 10% of the input values. For cases with 9 parameter fits inclusive of a multi-component neutral velocity distribution function the quality of the fits is degraded. Simultaneous fitting of the D 3 -> 2 and 4 -> 3 profiles improves the fit quality significantly, highlighting the importance of complementary spectroscopic measurements for divertor plasma emission studies.
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| 42. |
- Maxwell, Karen L., et al.
(författare)
-
Protein folding : Defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins
- 2005
-
Ingår i: Protein Science. - : Wiley. - 0961-8368 .- 1469-896X. ; 14, s. 602-16
-
Tidskriftsartikel (refereegranskat)abstract
- Recent years have seen the publication of both empirical and theoretical relationships predicting the rates with which proteins fold. Our ability to test and refine these relationships has been limited, however, by a variety of difficulties associated with the comparison of folding and unfolding rates, thermodynamics, and structure across diverse sets of proteins. These difficulties include the wide, potentially confounding range of experimental conditions and methods employed to date and the difficulty of obtaining correct and complete sequence and structural details for the characterized constructs. The lack of a single approach to data analysis and error estimation, or even of a common set of units and reporting standards, further hinders comparative studies of folding. In an effort to overcome these problems, we define here a "consensus" set of experimental conditions (25°C at pH 7.0, 50 mM buffer), data analysis methods, and data reporting standards that we hope will provide a benchmark for experimental studies. We take the first step in this initiative by describing the folding kinetics of 30 apparently two-state proteins or protein domains under the consensus conditions. The goal of our efforts is to set uniform standards for the experimental community and to initiate an accumulating, self-consistent data set that will aid ongoing efforts to understand the folding process.
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| 43. |
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| 44. |
- Nocente, M., et al.
(författare)
-
Fast ion energy distribution from third harmonic radio frequency heating measured with a single crystal diamond detector at the Joint European Torus
- 2015
-
Ingår i: Review of Scientific Instruments. - : AMER INST PHYSICS. - 0034-6748 .- 1089-7623. ; 86:10
-
Tidskriftsartikel (refereegranskat)abstract
- Neutron spectroscopy measurements with a single crystal diamond detector have been carried out at JET, for the first time in an experiment aimed at accelerating deuterons to MeV energies with radio frequency heating at the third harmonic. Data are interpreted by means of the expected response function of the detector and are used to extract parameters of the highly non-Maxwellian distribution function generated in this scenario. A comparison with observations using a time of flight and liquid scintillator neutron spectrometers is also presented. The results demonstrate the capability of diamond detectors to contribute to fast ion physics studies at JET and are of more general relevance in view of the application of such detectors for spectroscopy measurements in the neutron camera of next step tokamak devices.
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| 45. |
- Obryk, B., et al.
(författare)
-
TLD calibration for neutron fluence measurements at JET fusion facility
- 2018
-
Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : ELSEVIER. - 0168-9002 .- 1872-9576. ; 904, s. 202-213
-
Tidskriftsartikel (refereegranskat)abstract
- Measurements of neutron streaming through penetrations in biological shields are being carried out at JET fusion device by means of thermoluminescence (TL) detectors with the objective to validate the neutronics codes and nuclear data widely applied in ITER nuclear analyses in a real fusion environment. TLDs response due to the neutron component of the radiation field is related to the neutron fluence in a well-defined neutron energy spectrum. Therefore, a TLDs calibration in real fusion radiation fields is necessary to allow neutron fluence from TL measurements at JET to be more precisely calculated. Hence, a MCP-N and MCP-7 TLDs produced at the IFJ PAN in Krakow were calibrated at the ENEA facilities of Frascati and Casaccia laboratories. The obtained results have been analysed and new calibration factors are proposed. The detection system based on TLDs developed and calibrated for JET experiments can then be generally applied not only to fusion neutron fields, but also to ITER to monitor the neutron fluence outside the biological shield.
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| 46. |
- Packer, L. W., et al.
(författare)
-
Activation of ITER materials in JET : nuclear characterisation experiments for the long-term irradiation station
- 2018
-
Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 58:9
-
Tidskriftsartikel (refereegranskat)abstract
- This paper details progress in experimental characterisation work at JET for the long-term irradiation station, conducted as part of a project to perform activation experiments using ITER materials. The aim is to take advantage of the significant 14 MeV neutron yield expected during JET operations to irradiate samples of materials that will be used in the manufacturing of ITER tokamak components, such as Nb3Sn, SS316L steels from a range of manufacturers, SS304B, Alloy 660, W, CuCrZr, OF-Cu, XM-19, Al bronze, NbTi and EUROFER. This paper presents an assessment of the nuclear environment at the relevant irradiation locations at JET, measured using a range of high purity dosimetry foils: Ti, Ni, Y, Fe, Co, Sc, and Ta, irradiated with fusion neutrons at JET over a period of 15 months. Experimental results arc presented and compared to simulation predictions using a JET MCNP model coupled with the FISPACT-II inventory code. Comparisons are made for a total of 11 nuclear reactions using a range of nuclear data libraries in calculations.
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| 47. |
- Salewski, M., et al.
(författare)
-
MeV-range velocity-space tomography from gamma-ray and neutron emission spectrometry measurements at JET
- 2017
-
Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 57:5
-
Tidskriftsartikel (refereegranskat)abstract
- We demonstrate the measurement of a 2D MeV-range ion velocity distribution function by velocity-space tomography at JET. Deuterium ions were accelerated into the MeV-range by third harmonic ion cyclotron resonance heating. We made measurements with three neutron emission spectrometers and a high-resolution gamma-ray spectrometer detecting the gamma-rays released in two reactions. The tomographic inversion based on these five spectra is in excellent agreement with numerical simulations with the ASCOT-RFOF and the SPOT-RFOF codes. The length of the measured fast-ion tail corroborates the prediction that very few particles are accelerated above 2 MeV due to the weak wave-particle interaction at higher energies.
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| 48. |
- Santos, B., et al.
(författare)
-
Control and data acquisition software upgrade for JET gamma-ray diagnostics
- 2018
-
Ingår i: Fusion engineering and design. - : ELSEVIER SCIENCE SA. - 0920-3796 .- 1873-7196. ; 128, s. 117-121
-
Tidskriftsartikel (refereegranskat)abstract
- The Joint European Torus (JET), the largest magnetic confinement plasma physics experiment in operation, has a large amount of key diagnostics for physics exploration and machine operation, which include several Gamma Ray Diagnostics. The Gamma-Ray Spectrometer (GRS), Gamma Camera (GC) and Gamma-Ray Spectrometer Upgrade (GSU) diagnostics have similar Control and Data Acquisition Systems (CDAQ) based on the Advanced Telecommunication Computing Architecture standard, featuring Field Programmable Gate Arrays for data processing and management. During past JET-EP2 enhancements, the GRS and GC diagnostics were successfully installed and commissioned. However, the installed CDAQ software that interfaces these diagnostics to JET Control and Data Acquisition System is different, requiring higher maintenance costs. Benefiting from the Gamma Camera Upgrade (GCU) and new GSU installation and commissioning, the upgrading of the software and controller hardware used in the GRS and GC was evaluated, aiming at software standardization between all three diagnostics for easier maintenance. This paper describes the software standardization process between the diagnostics towards the usage of the same CDAQ software as well as the same Operating System (OS) for the controllers, which allows the operator to minimize the maintenance time, avoiding the need for system specific expertise. The rationale behind the choice of MARTe framework as CDAQ software and Scientific Linux as OS will also be presented.
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| 49. |
- Tamain, P., et al.
(författare)
-
Investigation of the influence of divertor recycling on global plasma confinement in JET ITER-like wall
- 2015
-
Ingår i: Journal of Nuclear Materials. - : Elsevier BV. - 0022-3115 .- 1873-4820. ; 463, s. 450-454
-
Tidskriftsartikel (refereegranskat)abstract
- The impact of the divertor geometry on global plasma confinement in type I ELMy H-mode has been investigated in the JET tokamak equipped with ITER-Like Wall. Discharges have been performed in which the position of the strike-points was changed while keeping the bulk plasma equilibrium essentially unchanged. Large variations of the global plasma confinement have been observed, the H-98 factor changing from typically 0.7 when the outer strike-point is on the vertical or horizontal targets to 0.9 when it is located in the pump duct entrance. Profiles are mainly impacted in the pedestal but core gradient lengths, especially for the density, are also modified. Although substantial differences are observed in the divertor conditions, none seem to correlate directly with the confinement. Modelling with the EDGE2D-EIRENE and SOLEDGE2D-EIRENE transport codes exhibits differences in the energy losses due to neutrals inside the separatrix, but orders of magnitude are too low to explain simply the impact on the confinement.
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| 50. |
- van Milligen, B. Ph, et al.
(författare)
-
Radial variation of heat transport in L-mode JET discharges
- 2019
-
Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 59:5
-
Tidskriftsartikel (refereegranskat)abstract
- In this paper, we analyze heat transport in the JET tokamak using data from its high resolution ECE diagnostic and analyses based on the transfer entropy (TE). The analysis reveals that heat transport is not smooth and continuous, but is characterized by 'trapping regions' separated by `minor transport barriers'. Meat may 'jump over' these barriers and when the heating power is raised, this 'jumping' behavior becomes more prominent. To check that our results are relevant for global heat transport, we deduced an effective diffusion coefficient from the TE results. Both its value and overall radial variation are consistent with heat diffusivities reported in literature. The detailed radial structure of the effective diffusion coefficient was shown to be linked to the mentioned minor transport barriers.
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