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Sökning: WFRF:(Shrestha Jesus)

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1.
  • Emmelmann, Marc, et al. (författare)
  • Deliverable 6.2: Trials and experimentation (cycle 2)
  • 2020
  • Rapport (refereegranskat)abstract
    • This deliverable presents the second cycle of trials and experimentation activities executed over 5GENESIS facilities. The document is the continuation of deliverable D6.1, in the sense that it captures tests carried out over the evolved infrastructures hosting 5GENESIS facilities following the methodology defined in D6.1. In this document 8 main KPIs and 4 application specific validation trials achieved, under 123 experiments that performed in total. The tests focus more on i) the evolved 5G infrastructure deployments that includes radio and core elements in non-standalone (NSA) deployment configurations based on commercial and open implementations, and ii) the use of Open 5GENESIS Suite for the execution of the tests.
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2.
  • Paudel, Keshav Raj, et al. (författare)
  • Recent Advances in Chronotherapy Targeting Respiratory Diseases
  • 2021
  • Ingår i: Pharmaceutics. - : MDPI. - 1999-4923. ; 13:12
  • Forskningsöversikt (refereegranskat)abstract
    • Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep-wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual's circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.
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