| 1. |
- Bockli, P., et al.
(författare)
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A Proposal for the Reform of Group Law in Europe
- 2017
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Ingår i: European Business Organization Law Review. - : Springer Science and Business Media LLC. - 1566-7529 .- 1741-6205. ; 18:1, s. 1-49
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Tidskriftsartikel (refereegranskat)abstract
- The legal regime applicable to groups of companies in the European Union has been discussed for many years. National legislations have been adopted in a certain number of Member States, and new initiatives are being considered by the European Commission and in academic writing. The central issues in groups of companies is the relationship between the controlling shareholder, often the parent company and the subsidiaries, and the potential for abuse to the detriment of the latter's minority shareholders and creditors. Several answers have been formulated, ranging from a duty of the parent to indemnify the subsidiary for the charges imposed by the parent, to the acceptance of these charges provided they result in some benefit to the subsidiary and do not endanger the subsidiary's solvency. In another approach, these issues may be solved by other common company law, e.g., on the basis of the unfair prejudice provisions. With respect to shareholder and creditor protection, a comparative analysis concludes that there is no need for additional regulatory safeguards. The present approaches indicate that group relations are often characterised by conflicts of interest. Therefore, it is proposed to develop a standard for dealing with these, especially under the form of related party transactions. The specific conditions for dealing with intragroup related party transactions are submitted for further discussion.
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| 2. |
- Radenkovic, M., et al.
(författare)
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Characterization of resident lymphocytes in human pancreatic islets
- 2017
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Ingår i: Clinical and Experimental Immunology. - : Oxford University Press (OUP). - 0009-9104 .- 1365-2249. ; 187:3, s. 418-427
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Tidskriftsartikel (refereegranskat)abstract
- The current view of type 1 diabetes (T1D) is that it is an immune-mediated disease where lymphocytes infiltrate the pancreatic islets, promote killing of beta cells and cause overt diabetes. Although tissue resident immune cells have been demonstrated in several organs, the composition of lymphocytes in human healthy pancreatic islets have been scarcely studied. Here we aimed to investigate the phenotype of immune cells associated with human islets of non-diabetic organ donors. A flow cytometry analysis of isolated islets from perfused pancreases (n = 38) was employed to identify alpha, beta, T, natural killer (NK) and B cells. Moreover, the expression of insulin and glucagon transcripts was evaluated by RNA sequencing. Up to 80% of the lymphocytes were CD3(+) T cells with a remarkable bias towards CD8(+) cells. Central memory and effector memory phenotypes dominated within the CD8(+) and CD4(+) T cells and most CD8(+) T cells were positive for CD69 and up to 50-70% for CD103, both markers of resident memory cells. The frequency of B and NK cells was low in most islet preparations (12 and 3% of CD45(+) cells, respectively), and the frequency of alpha and beta cells varied between donors and correlated clearly with insulin and glucagon mRNA expression. In conclusion, we demonstrated the predominance of canonical tissue resident memory CD8(+) T cells associated with human islets. We believe that these results are important to understand more clearly the immunobiology of human islets and the disease-related phenotypes observed in diabetes.
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| 3. |
- Davies, P., et al.
(författare)
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The Commission's 2018 Proposal on Cross-Border Mobility - An Assessment
- 2019
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Ingår i: European Company and Financial Law Review. - : Walter de Gruyter GmbH. - 1613-2556 .- 1613-2548. ; 16:1-2, s. 196-221
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Tidskriftsartikel (refereegranskat)abstract
- Currently, the Council of the European Union is negotiating the European Commission's recent proposal on cross-border mobility. This paper provides an overall assessment based on the proposal's central pillars: freedom of establishment and protection of the interests of creditors, shareholders, and employees. The proposed directive meets a real necessity for regulation on a European level and pursues an ambitious agenda. While the general approach is excellent, there is room for improvement on some issues of importance.
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| 4. |
- Edwards, Y., et al.
(författare)
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Quality-assured solutions for green roof gardens on concrete decks with zero tolerance for leaks
- 2014
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Ingår i: Wit Transactions on Ecology and The Environment. - : WITPress. - 1746-448X .- 1743-3541. ; 191, s. 635-645
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Tidskriftsartikel (refereegranskat)abstract
- Eco neighborhoods with green infrastructure solutions are increasingly being prescribed today in Swedish cities for reducing and attenuating storm water runoff, increasing biodiversity, having a temperature moderating effect and for energy saving. Thus, contractors are simply required to build with green gardens on concrete decks, such as green roofs, green terraces, green courtyards and green complete neighborhoods. A lot of knowledge and experience is in fact lacking today, and consequences may therefore be devastating. If green system solutions are to be seen as an obvious choice in future settlements, and not as a problem, there must be clear guidelines and specifications that ensure a sustainable outcome. This is missing today. This paper reports a project aiming at bringing together researchers, government and industry to the collaborative development of new and attractive solutions for green roof gardens with consideration to the environment and high requirements for durability, materials, construction and energy efficiency. These solutions must also be adaptable to similar types of facilities, specific needs and environments. One such area concerns public land such as parks, streets and squares on concrete decks. Certification and tailored guidelines for different types of systems are being developed. The initiating part of this project clearly indicates that there is a need for better understanding, more research and long term monitoring/follow up of green roofs. Furthermore, a holistic approach is introduced to ensure that one good green roof function will not have severe negative effects on other functions.
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| 5. |
- Fiorenzi, Marco, et al.
(författare)
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Enhancing TCP over HSDPA by cross-layer signalling
- 2007
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Ingår i: GLOBECOM 2007: 2007 IEEE GLOBAL TELECOMMUNICATIONS CONFERENCE. - 9781424410422 ; , s. 5362-5366
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Konferensbidrag (refereegranskat)abstract
- A comprehensive performance evaluation of a cross-layer solution to increase users' downlink data rates over HSDPA is provided. The solution consists of a proxy entity between a server and the Radio Network Controller, and cross-layer signalling from the base station to the proxy. The performance of the solution is evaluated though a detailed ns-2 simulator environment, which includes all HSDPA features, as well as some existing TCP enhancing protocols widely adopted for internet traffic over wireless links. Numerical results show that the proxy significantly increases the users' throughput, while also improving the utilization of the radio resources.
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| 6. |
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| 7. |
- Knol, Jeroen J, et al.
(författare)
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A study on the use of empirical models to predict the formation of acrylamide in potato crisps
- 2008
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Ingår i: Molecular Nutrition and Food Research. - : Wiley. - 1613-4133 .- 1613-4125. ; 52:3, s. 313-321
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Tidskriftsartikel (refereegranskat)abstract
- The formation of acrylamide in potato crisps was fitted by empirical mathematical models. Potato slices were fried under the same experimental conditions for different times. Besides the content of precursors in the raw potato slices, acrylamide and water content in the potato crisps were quantified after predetermined times (2-6 min). The temperature developments in the surrounding oil and outer cell layer of the potato slices were monitored, giving more insight in the frying process and making future comparisons between studies possible. The pattern found for the formation of acrylamide, which was similar to earlier studies, was fitted to three empirical models. Statistical methods were used to compare the performance of the models, with the "Logistic-Exponential" and "Empirical" model performing equally well. The obtained model parameters were in the range of earlier reported studies, although this comparison is not unequivocal as the experimental conditions differed between studies. The precision of parameter estimates was problematic; this should be improved by better experimental design. Nevertheless, the approach of this study will make it possible to truly compare acrylamide formation patterns and model parameters in the future, with the ability to develop a tool to predict acrylamide formation in potato crisps.
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| 8. |
- Nilsson, R. Jonas A., et al.
(författare)
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Blood platelets contain tumor-derived RNA biomarkers
- 2011
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Ingår i: Blood. - New York : American Society of Hematology. - 0006-4971 .- 1528-0020. ; 118:13, s. 3680-3683
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Tidskriftsartikel (refereegranskat)abstract
- Diagnostic platforms providing biomarkers that are highly predictive for diagnosing, monitoring, and stratifying cancer patients are key instruments in the development of personalized medicine. We demonstrate that tumor cells transfer (mutant) RNA into blood platelets in vitro and in vivo, and show that blood platelets isolated from glioma and prostate cancer patients contain the cancer-associated RNA biomarkers EGFRvIII and PCA3, respectively. In addition, gene-expression profiling revealed a distinct RNA signature in platelets from glioma patients compared with normal control subjects. Because platelets are easily accessible and isolated, they may form an attractive platform for the companion diagnostics of cancer.
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| 9. |
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| 10. |
- Wahlström, Johan, et al.
(författare)
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Map-Aided Dead-Reckoning Using only Measurements of Speed
- 2016
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Ingår i: IEEE Transactions on Intelligent Vehicles. - : Institute of Electrical and Electronics Engineers (IEEE). - 2379-8858 .- 2379-8904. ; 1:3, s. 244-253
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Tidskriftsartikel (refereegranskat)abstract
- We present a particle-based framework for estimating the position of a vehicle using map information and measurements of speed. The filter propagates the particles' position estimates by means of dead-reckoning, and then updates the particle weights using two measurement functions. The first measurement function is based on the assumption that the lateral force on the vehicle does not exceed critical limits derived from physical constraints. The second is based on the assumption that the driver approaches a target speed derived from the speed limits along the upcoming trajectory. Assuming some prior knowledge of the initial position, performance evaluations of the proposed method indicate that end destinations often can be estimated with an accuracy in the order of 100, m. These results expose the sensitivity and commercial value of speed data collected in many of today's insurance telematics programs, where the data is used to adjust premiums and provide driver feedback. We end by discussing the strengths and weaknesses of different methods for anonymization and privacy preservation in telematics programs.
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