| 1. |
- Al-Khatib, A, et al.
(författare)
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Transition to non-collective states at high spin in Xe-124
- 2008
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Ingår i: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 36:1, s. 21-29
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in Xe-124 were populated in the reaction Se-82(Ca-48, 6n) Xe-124 and gamma-ray coincidence relationships were measured with the Gammasphere spectrometer. Two new bands are observed and several of the previously known bands are extended in the high-as well as in the low-spin region. Two irregular high-spin structures are also added. The irregularities are a fingerprint of a transition from collective to non-collective behaviour. Configuration assignments to the new structures are proposed on the basis of systematics and by comparing experimental properties with calculations within the framework of the cranking model.
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| 2. |
- Amarzguioui, Mohammed, et al.
(författare)
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Extensive Intimal Apolipoprotein A1-Derived Amyloid Deposits in a Patient with an Apolipoprotein A1 Mutation
- 1998
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Ingår i: Biochemical and Biophysical Research Communications - BBRC. - : Elsevier BV. - 0006-291X .- 1090-2104. ; 242:3, s. 534-539
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Tidskriftsartikel (refereegranskat)abstract
- In the aortic intima amyloid deposits are often associated with atherosclerotic plaques. In a recent study of one patient with aortic intimal amyloid the major fibril protein was an N-terminal fragment of apolipoprotein A1 (apoA1) consisting of 69 amino acid residues. In the present study, we have screened the apoA1 gene for mutations in autopsy cases with aortic intimal amyloid immunohistochemically positive for apoA1, using single stranded conformational polymorphism (SSCP) analysis and DNA sequencing. All cases except one had a normal apoA1 gene sequence. One case of exceptionally severe atherosclerosis combined with extensive intimal amyloid deposits showed an apoA1 deletion corresponding to Lys 107. Thus, wild type apoA1 is amyloidogenic but our findings suggest that the expression of a mutant apoA1-form may be associated with enhanced amyloidogenicity.
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| 3. |
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| 4. |
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| 5. |
- Andgren, Karin, et al.
(författare)
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Low-spin collective behavior in the transitional nuclei Mo-86,Mo-88
- 2007
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 76:1, s. 014307-
-
Tidskriftsartikel (refereegranskat)abstract
- Low-spin structures in Mo-86,Mo-88 were populated using the Ni-58(Ar-36, x alpha yp) heavy-ion fusion-evaporation reaction at a beam energy of 111 MeV. Charged particles and gamma rays were emitted in the reactions and detected by the DIAMANT CsI ball and the EXOGAM Ge array, respectively. In addition to the previously reported low-to-medium spin states in these nuclei, new low-spin structures were observed. Angular correlation and linear polarization measurements were performed in order to unambiguously determine the spins and parities of intensely populated states in Mo-88. Quasiparticle Random Phase Approximation (QRPA) calculations were performed for the first and second excited 2(+) states in Mo-86 and Mo-88. The results are in qualitative agreement with the experimental results, supporting a collective interpretation of the low-spin states for these transitional nuclei.
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| 6. |
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| 7. |
- Ashrafi, S., et al.
(författare)
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Monte-Carlo simulation of the charged particle detector used in the NORDBALL gamma-ray spectrometer
- 2001
-
Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - 0168-9002 .- 1872-9576. ; 458:3, s. 690-697
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Tidskriftsartikel (refereegranskat)abstract
- The NORDBALL silicon detector array for detecting light charged particles emitted in fusion evaporation reactions was simulated with the Monte-Carlo method. The data from the reaction of 261 MeV Ni-58 ions with Cr-50 nuclei in a 4.8 mg/cm(2) thick target was used to adjust the simulation parameters. Relative population of residual nuclei in the reaction was determined, by comparing the intensities of gamma -rays.
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| 8. |
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| 9. |
- Atac, A, et al.
(författare)
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Single-step link of the superdeformed band in Eu-143
- 1996
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Ingår i: ZEITSCHRIFT FUR PHYSIK A-HADRONS AND NUCLEI. - : SPRINGER VERLAG. - 0939-7922. ; 355:4, s. 343-344
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- A discrete gamma-ray transition with an energy of 3360.6 keV deexciting the second lowest SD state in Eu-143 has been discovered. It carries 3.2 % of the full intensity of the band and feeds into a nearly spherical state which is above the I = 35/2((+)),
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| 10. |
- Axelsson, A, et al.
(författare)
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Excited superdeformed band in Eu-143
- 1999
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Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 6:2, s. 175-183
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Tidskriftsartikel (refereegranskat)abstract
- A new superdeformed band has been discovered in a EUROBALL experiment and assigned to Eu-143. It has a maximum intensity of 35% of the Eu-143 yrast superdeformed band and the transition energies of the two bands are very similar. Based on comparison with cranked shell model calculations the new band is tentatively assigned the high-N intruder configuration pi 6(2)nu 7(0) and the parity and signature quantum numbers (pi, alpha) = (-1, +1/2). In addition to the already known high-energy transition at 3361 keV another discrete line at 2715 keV was found to be in coincidence with the yrast superdeformed band. However, it was not possible to connect the decay out of either of the superdeformed bands to, known normally deformed states.
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| 11. |
- Axelsson, A, et al.
(författare)
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Excited superdeformed band in Eu-143
- 1999
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Ingår i: EUROPEAN PHYSICAL JOURNAL A. - : SPRINGER VERLAG. - 1434-6001. ; 6:2, s. 175-183
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- A new superdeformed band has been discovered in a EUROBALL experiment and assigned to Eu-143. It has a maximum intensity of 35% of the Eu-143 yrast superdeformed band and the transition energies of the two bands are very similar. Based on comparison with
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| 12. |
- Axelsson, A, et al.
(författare)
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Single-step link from yrast SD band in Eu-143
- 1997
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Ingår i: PROGRESS IN PARTICLE AND NUCLEAR PHYSICS. - : PERGAMON PRESS LTD. - 0146-6410. ; 38, s. 51-52
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- A discrete gamma-ray transition from the yrast SD band to the region of near-yrast discrete normal-deformed states has been identified in Eu-143. It has an energy of 3360.6 keV and an intensity corresponding to 3.2% of the full intensity of the SD band an
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| 13. |
- Basu, Anwesha, et al.
(författare)
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Evolution of collective and noncollective structures in Xe 123
- 2020
-
Ingår i: Physical Review C. - 2469-9985. ; 101:2
-
Tidskriftsartikel (refereegranskat)abstract
- An experiment involving a heavy-ion-induced fusion-evaporation reaction was carried out where high-spin states of Xe123 were populated in the Se80(Ca48,5n)Xe123 reaction at 207 MeV beam energy. Gamma-ray coincidence events were recorded with the Gammasphere Ge detector array. The previously known level scheme was confirmed and enhanced with the addition of five new band structures and several interband transitions. Cranked Nilsson-Strutinsky (CNS) calculations were performed and compared with the experimental results in order to assign configurations to the bands.
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| 14. |
- Basu, Anwesha, et al.
(författare)
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Highly deformed band structures due to core excitations in Xe 123
- 2021
-
Ingår i: Physical Review C. - 2469-9985. ; 103:1
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Xe123 were populated in the Se80(Ca48, 5n)Xe123 reaction at a beam energy of 207 MeV. γ-ray coincidence events were recorded with the Gammasphere spectrometer. Four new high-spin bands have been discovered in this nucleus. The bands are compared with those calculated within the framework of cranked Nilsson-Strutinsky and cranked Nilsson-Strutinsky-Bogoliubov models. It is concluded that the configurations of the bands involve two-proton excitations across the Z=50 as well as excitation of neutrons across the N=82 shell gaps resulting in a large deformation, 2≈0.30 and γ≈5°C.
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| 15. |
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| 16. |
- Bergström, Joakim, et al.
(författare)
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Two different types of amyloid deposits - apolipoprotein A-IV and transthyretin - in a patient with systemic amyloidosis
- 2004
-
Ingår i: Lab. Invest.. ; 84, s. 981-988
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Tidskriftsartikel (refereegranskat)abstract
- Certain forms of systemic amyloidosis have been associated with the pathologic deposition as fibrils of three different apolipoprotein-related proteins--apolipoprotein A-I, apolipoprotein A-II, and serum amyloid A. We have previously reported (Bergstrom et al, Biochem Biophys Res Commun 2001;285:903-908) that amyloid fibrils extracted from the heart of an elderly male with senile systemic amyloidosis contained, in addition to wild-type transthyretin-related molecules, an N-terminal fragment of yet a fourth apolipoprotein--apolipoprotein A-IV (apoA-IV). We now provide the results of our studies that have established the complete amino-acid sequence of this approximately 70-residue component and, additionally, have shown this protein to be the product of an unmutated apoA-IV gene. Notably, the apoA-IV and transthyretin fibrils were not codeposited but, rather, had anatomically distinct patterns of distribution within the heart and other organs, as evidenced immunohistochemically, by variation in the ultra structural morphology and by differences in the intensity of Congo red birefringence. These findings provide the first conclusive evidence that two separate forms of amyloid, each derived from a wild-type amyloidogenic precursor protein, were present in a patient with systemic amyloidosis.
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| 17. |
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| 18. |
- Bhowal, S., et al.
(författare)
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Development of collective structures over noncollective excitations in Nd-139
- 2011
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 84:2
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Nd-139 were investigated using the reaction Zr-96(Ca-48,5n) at a beam energy of 195 MeV and gamma-ray coincidences were acquired with the Euroball spectrometer. Apart from several dipole bands at medium excitation energy, three quadrupole bands have been observed at high spin. Linking transitions connecting two of the high-spin bands to low-energy states have been observed. Calculations based on the cranked-Nilsson-Strutinsky formalism have been used to assign configurations for the high-spin quadrupole bands.
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| 19. |
- Caceres, L., et al.
(författare)
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Nuclear structure studies of F-24
- 2015
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 92:1
-
Tidskriftsartikel (refereegranskat)abstract
- The structure of the F-24 nucleus has been studied at GANIL using the beta decay of O-24 and the in-beam.-ray spectroscopy from the fragmentation of Na-27,Na-28, Ne-25,Ne-26, and Mg-29,Mg-30 nuclei. Combining these complementary experimental techniques, the level scheme of F-24 has been constructed up to 3.6 MeV by means of particle-gamma and particle-gamma gamma coincidence relations. Experimental results are compared to shell-model calculations using the standard USDA and USDB interactions as well as ab initio valence-space Hamiltonians calculated from the in-medium similarity renormalization group based on chiral two- and three-nucleon forces. Both methods reproduce the measured level spacings well, and this close agreement allows unidentified spins and parities to be consistently assigned.
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| 20. |
- CEDERKALL, J, et al.
(författare)
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1ST OBSERVATION OF EXCITED-STATES IN SB-108
- 1995
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 581:1, s. 189-204
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Tidskriftsartikel (refereegranskat)abstract
- A spectroscopic study of Sb-108 has been carried out as a part of a larger experiment where in total twenty-nine different residual nuclei were identified. This study gives the first information on excited levels in this nucleus. A low-lying two-quasi-particle multiplet together with some of the higher lying levels are discussed within the framework of the nuclear shell model. A rotational, strongly coupled, band is identified as, most likely, being built on the deformed pig9/2(-1) nuh11/2 configuration in accordance with total routhian surface calculations. Tentative spins and parities are presented as well as B(M1)/B(E2) ratios for some of the transitions in the strongly coupled band.
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| 21. |
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| 22. |
- Cederkäll, Joakim, et al.
(författare)
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Sub-Barrier Coulomb Excitation of ^110Sn and Its Implications for the ^100Sn Shell Closure
- 2007
-
Ingår i: Physical Review Letters. - 1079-7114. ; 98:17, s. 172501-
-
Tidskriftsartikel (refereegranskat)abstract
- The first excited 2+ state of the unstable isotope 110Sn has been studied in safe Coulomb excitation at 2.82 MeV/u using the MINIBALL array at the REX-ISOLDE post accelerator at CERN. This is the first measurement of the reduced transition probability of this state using this method for a neutron deficient Sn isotope. The strength of the approach lies in the excellent peak-to-background ratio that is achieved. The extracted reduced transition probability, B(E2:0+-->2+)=0.220±0.022e2b2, strengthens the observation of the evolution of the B(E2) values of neutron deficient Sn isotopes that was observed recently in intermediate-energy Coulomb excitation of 108Sn. It implies that the trend of these reduced transition probabilities in the even-even Sn isotopes is not symmetric with respect to the midshell mass number A=116 as 100Sn is approached.
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| 23. |
- Cederwall, Bo, et al.
(författare)
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Evidence for a spin-aligned neutron-proton paired phase from the level structure of 92Pd
- 2011
-
Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 469:7328, s. 68-71
-
Tidskriftsartikel (refereegranskat)abstract
- Shell structure and magic numbers in atomic nuclei were generally explained by pioneering work(1) that introduced a strong spin-orbit interaction to the nuclear shell model potential. However, knowledge of nuclear forces and the mechanisms governing the structure of nuclei, in particular far from stability, is still incomplete. In nuclei with equal neutron and proton numbers (N = Z), enhanced correlations arise between neutrons and protons (two distinct types of fermions) that occupy orbitals with the same quantum numbers. Such correlations have been predicted to favour an unusual type of nuclear superfluidity, termed isoscalar neutron-proton pairing(2-6), in addition to normal isovector pairing. Despite many experimental efforts, these predictions have not been confirmed. Here we report the experimental observation of excited states in the N = Z = 46 nucleus Pd-92. Gamma rays emitted following the Ni-58(Ar-36,2n)Pd-92 fusion-evaporation reaction were identified using a combination of state-of-the-art high-resolution c-ray, charged-particle and neutron detector systems. Our results reveal evidence for a spin-aligned, isoscalar neutron-proton coupling scheme, different from the previous prediction(2-6). We suggest that this coupling scheme replaces normal superfluidity (characterized by seniority coupling(7,8)) in the ground and low-lying excited states of the heaviest N = Z nuclei. Such strong, isoscalar neutron-proton correlations would have a considerable impact on the nuclear level structure and possibly influence the dynamics of rapid proton capture in stellar nucleosynthesis.
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| 24. |
- de Walle, J. V., et al.
(författare)
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Coulomb excitation of the N=50 nucleus Zn-80
- 2008
-
Ingår i: AIP Conference Proceedings. - 1551-7616 .- 0094-243X. ; 1012, s. 291-295 453
-
Konferensbidrag (refereegranskat)abstract
- Neutron rich Zinc isotopes, including the N=50 nucleus Zn-80, were produced and post-accelerated at the Radioactive Ion Beam (RIB) facility REX-ISOLDE (CERN). Low-energy Coulomb excitation was induced on these isotopes after post-acceleration, yielding B(E2) strengths to the first excited 2(+) states. For the first time, an excited state in Zn-80 was observed and the 2(1)(+) state in Zn-78 was established. The measured B(E2,2(1)(+) -> 0(1)(+)) values are compared to two sets of large scale shell model calculations. Both calculations reproduce the observed B(E2) systematics for the full Zinc isotopic chain. The results for N=50 isotones indicate a good N=50 shell closure and a strong Z=28 proton core polarization. The new results serve as benchmarks to establish theoretical models, predicting the nuclear properties of the doubly magic nucleus Ni-78.
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| 25. |
- Diriken, J., et al.
(författare)
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Coulomb excitation of Ga-73
- 2010
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 82:6
-
Tidskriftsartikel (refereegranskat)abstract
- The B(E2; I-i -> I-f) values for transitions in Ga-71(31)40 and Ga-73(31)42 were deduced from a Coulomb excitation experiment at the safe energy of 2.95 MeV/nucleon using post-accelerated beams of Ga-71,Ga-73 at the REX-ISOLDE on-line isotope mass separator facility. The emitted gamma rays were detected by the MINIBALL gamma-detector array, and B(E2; I-i -> I-f) values were obtained from the yields normalized to the known strength of the 2(+) -> 0(+) transition in the Sn-120 target. The comparison of these new results with the data of less neutron-rich gallium isotopes shows a shift of the E2 collectivity toward lower excitation energy when adding neutrons beyond N = 40. This supports conclusions from previous studies of the gallium isotopes, which indicated a structural change in this isotopic chain between N = 40 and 42. Combined with recent measurements from collinear laser spectroscopy showing a 1/2(-) spin and parity for the ground state, the extracted results revealed evidence for a 1/2(-), 3/2(-) doublet near the ground state in Ga-73(31)42 differing by at most 0.8 keV in energy.
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| 26. |
- DOMBRADI, Z, et al.
(författare)
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HIGH-SPIN SPECTROSCOPY OF TE-109
- 1995
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 51:5, s. 2394-2399
-
Tidskriftsartikel (refereegranskat)
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| 27. |
- DOMBRADI, Z, et al.
(författare)
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IDENTIFICATION AND SPECTROSCOPY OF THE TE-108 NUCLEUS
- 1994
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Ingår i: Zeitschrift für Physik A Hadrons and Nuclei. - 0939-7922 .- 1431-5831. ; 350:1, s. 3-4
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states of Te-108 were populated in the Fe-54 + Ni-58 (270 MeV) reaction using the NORDBALL detector array equipped with charged-particle and neutron detector systems for reaction channel separation. Gamma rays belonging to the neutron deficient nucleus Te-108 were identified for the first time. On the basis of gammagamma-coincidence and angular correlation relations a level scheme was constructed with tentative spin and parity assignments. The structure of the nucleus is discussed in the framework of systematics of heavier Te nuclei.
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| 28. |
- DORING, J, et al.
(författare)
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EVIDENCE FOR NEW ISOMERS AND BAND STRUCTURES IN RB-80
- 1992
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 46:6, s. R2127-R2131
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in the doubly odd nucleus Rb-80 have mainly been studied via the Zn-68(F-19,alpha3n) reaction at 72 MeV beam energy utilizing the NORDBALL detector system. The level scheme has been extended up to a (15+) state at 4446 keV excitation energy. In the low-spin region seven new isomers with lifetimes in the nanosecond region have been found. In addition, a 6+ isomer with a half-life of the order of mus has been identified at an excitation energy of 494.4 keV. For the level sequence built on this isomer positive parity is suggested and the states are ascribed to the intruder two-quasiparticle configuration (pig9/2 x nug9/2) and collective excitations.
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| 29. |
- DORING, J, et al.
(författare)
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HIGH-LYING 3-QUASI-PARTICLE BANDS AND SIGNATURE SPLITTING IN RB-81
- 1994
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 50:4, s. 1845-1850
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Tidskriftsartikel (refereegranskat)abstract
- Two new high-lying level sequences of negative parity have been identified in the odd-proton nucleus Rb-81 by in-beam gamma-ray spectroscopy using the reactions Br-79(alpha, 2n) at 27 MeV and Zn-68(F-19, alpha2n) at 72 MeV. One sequence, dominated by M1 transitions, is interpreted as a three-quasiparticle band predominantly containing a neutron in the p1/2, p3/2, or f5/2 subshell coupled to g9/2 proton and g9/2 neutron excitations. The other new level sequence forms the three-quasiparticle extension of the unfavored negative-parity band, but the states decay also by E1 transitions. The signature splitting points to a configuration where an aligned g9/2 proton pair is involved.
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| 30. |
- Ekström, Andreas, et al.
(författare)
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0(gs)+ -->2(1)+ transition strengths in 106Sn and 108Sn.
- 2008
-
Ingår i: Physical Review Letters. - 1079-7114. ; 101:1
-
Tidskriftsartikel (refereegranskat)abstract
- The reduced transition probabilities, B(E2; 0(gs)+ -->2(1)+), have been measured in the radioactive isotopes (108,106)Sn using subbarrier Coulomb excitation at the REX-ISOLDE facility at CERN. Deexcitation gamma rays were detected by the highly segmented MINIBALL Ge-detector array. The results, B(E2;0(gs)+ -->2(1)+)=0.222(19)e2b2 for 108Sn and B(E2; 0(gs)+-->2(1)+)=0.195(39)e2b2 for 106Sn were determined relative to a stable 58Ni target. The resulting B(E2) values are approximately 30% larger than shell-model predictions and deviate from the generalized seniority model. This experimental result may point towards a weakening of the N=Z=50 shell closure.
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| 31. |
- Ekström, Andreas, et al.
(författare)
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Coulomb excitation of Sn-110 using REX-ISOLDE
- 2006
-
Ingår i: Physica Scripta. - 1402-4896 .- 0031-8949. ; T125, s. 190-191
-
Konferensbidrag (refereegranskat)abstract
- In this paper, we report the preliminary result from the first Coulomb excitation experiment at REX-ISOLDE (Habs et al 1998 Nucl. Instrum. Methods B 139 128) using neutron-deficient Sn-beams. The motivation of the experiment is to deduce the reduced transition probability, B(E2; 2(+) -> 0(+)), for the sequence of neutron deficient, unstable, even-even Sn- isotopes from Sn-110 to ultimately Sn-110. Safe Coulomb excitation using a radioactive beam opens up a new path to study the lifetime of the first excited 2(+) state in these isotopes. The de-excitation path following fusion-evaporation reactions will for the even-even Sn isotopes pass via an isomeric 6(+) state, located at higher energy, which thus hampers measurements of the lifetime of the first excited state using, e. g., recoil-distance methods. For this reason the reduced transition probability of the first excited 2(+) state has remained unknown in this chain of isotopes although the B(E2) value of the stable isotope Sn-112 was measured approximately 30 years ago (see, e. g., Stelson et al 1970 Phys. Rev. C 2 2015). Our experiment is thus the first to accomplish a measurement of this quantity in Sn-110. It is believed that the determination of the B(E2) value in Sn-110 will indicate the turnover point from a trend of increasing B(E2) values for the heavier isotopes to a trend characterized by less collectivity. Our first preliminary result indicates that this assumption may well be correct.
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| 32. |
- Ekström, Andreas, et al.
(författare)
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Coulomb excitation of the odd-odd isotopes In-106,In-108
- 2010
-
Ingår i: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 44:3, s. 355-361
-
Tidskriftsartikel (refereegranskat)abstract
- The low-lying states in the odd-odd and unstable isotopes In-106,In-108 have been Coulomb excited from the ground state and the first excited isomeric state at the REX-ISOLDE facility at CERN. With the additional data provided here the pi g(9/2)(-1) circle times nu d(5/2) and pi g(9/2)(-1) circle times nu g7/2 multiplets have been re-analyzed and are modified compared to previous results. The observed gamma-ray de-excitation patterns were interpreted within a shell model calculation based on a realistic effective interaction. The agreement between theory and experiment is satisfactory and the calculations reproduce the observed differences in the excitation pattern of the two isotopes. The calculations exclude a 6(+) ground state in In-106. This is in agreement with the conclusions drawn using other techniques. Furthermore, based on the experimental results, it is also concluded that the ordering of the isomeric and ground state in In-108 is inverted compared to the shell model prediction. Limits on B(E2) values have been extracted where possible. A previously unknown low-lying state at 367 keV in In-106 is also reported.
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| 33. |
- Ellbrant, Julia, et al.
(författare)
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Adjacent Primary Care May Reduce Less Urgent Pediatric Emergency Department Visits
- 2020
-
Ingår i: Journal of Primary Care and Community Health. - : SAGE Publications. - 2150-1319 .- 2150-1327. ; 11
-
Tidskriftsartikel (refereegranskat)abstract
- Aims: Pediatric emergency department (ED) overcrowding is a challenge. This study was designed to evaluate if a hospital-integrated primary care unit (HPCU) reduces less urgent visits at a pediatric ED. Methods: This retrospective cross-sectional study was carried out at a university hospital in Sweden, where the HPCU, open outside office hours, had been integrated next to the ED. Children seeking ED care during 4-week high- and low-load study periods before (2012) and after (2015) implementation of the HPCU were included. Information on patient characteristics, ED management, and length of ED stay was obtained from hospital data registers. Results: In total, 3216 and 3074 ED patient visits were recorded in 2012 and 2015, respectively. During opening hours of the HPCU, the proportions of pediatric ED visits (28% lower; P <.001), visits in the lowest triage group (36% lower; P <.001), patients presenting with fever (P =.001) or ear pain (P <.001), and nonadmitted ED patients (P =.033), were significantly lower in 2015 than in 2012, whereas the proportion of infants ≤3 months was higher in 2015 (P <.001). Conclusions: By enabling adjacent management of less urgent pediatric patients at adequate lower levels of medical care, implementation of a HPCU outside office hours may contribute to fewer and more appropriate pediatric ED visits.
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| 34. |
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| 35. |
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| 36. |
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| 37. |
- Enqvist, Stina, et al.
(författare)
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Fibril protein fragmentation pattern in systemic AL-amyloidosis
- 2009
-
Ingår i: Journal of Pathology. - : Wiley. - 0022-3417 .- 1096-9896. ; 219:4, s. 473-480
-
Tidskriftsartikel (refereegranskat)abstract
- Immunoglobulin light chain (AL)-amyloidosis was one of the first types of amyloidosis discovered and still little is known about its pathogenic mechanisms. One major obstacle is the very heterogeneous condition; in fact, every patient could be considered to have their own disease since symptoms and outcome vary enormously. The reason for this is not known but intrinsic factors of the immunoglobulin light chain (LC) and the fact that every LC is unique seem to be important. Post-translational modifications such as glycosylation and proteolysis are most certainly involved. By using western blotting, we studied in detail the proteolytic pattern in six patients with AL-amyloidosis of kappa type with the aid of three peptide antisera against two domains in the constant segment and one conserved domain in framework 3 of the variable region. Materials from one to five organs were analysed. The result clearly demonstrates that the fragmentation pattern was similar in amyloid of different organs in one patient but differed greatly between patients. Full-length, N-, and C-terminal fragments were detected with the three antisera. The results strongly support the hypothesis that proteolytic cleavage occurs after fibril formation.
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| 38. |
- Enqvist, Stina, et al.
(författare)
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Germ Line Origin and Somatic Mutations Determine the Target Tissues in Systemic AL-Amyloidosis
- 2007
-
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 2:10, s. e981-
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are associated with severe diseases such as Alzheimeŕs disease, prion diseases and type-2 diabetes. Light chain (AL) -amyloidosis is unique among amyloid diseases in that the fibril protein, a monoclonal immunoglobulin light chain, varies between individuals and that no two AL-proteins with identical primary structures have been described to date. The variability in tissue distribution of amyloid deposits is considerably larger in systemic AL-amyloidosis than in any other form of amyloidosis. The reason for this variation is believed to be based on the differences in properties of the amyloidogenic immunoglobulin light chain. However, there is presently no known relationship between the structure of an AL-protein and tissue distribution. METHODOLOGY/PRINCIPAL FINDINGS: We compared the pattern of amyloid deposition in four individuals with amyloid protein derived from variable light chain gene O18-O8, the source of a high proportion of amyloidogenic light chains, and in whom all or most of the fibril protein had been determined by amino acid sequencing. In spite of great similarities between the structures of the proteins, there was a pronounced variability in deposition pattern. We also compared the tissue distribution in these four individuals with that of four other patients with AL-amyloid derived from the L2-L16 gene. Although the interindividual variations were pronounced, liver and kidney involvement was much more evident in the latter four. CONCLUSIONS/SIGNIFICANCE: We conclude that although the use of a specific gene influences the tissue distribution of amyloid, each light chain exhibits one or more determinants of organ-specificity, which originate from somatic mutations and post-translational modifications. Eventual identification of such determinants could lead to improved treatment of patients with AL amyloidosis.
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| 39. |
- FAHLANDER, C, et al.
(författare)
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IN-BEAM SPECTROSCOPY OF TE-110
- 1994
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 577:3-4, s. 773-785
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Tidskriftsartikel (refereegranskat)abstract
- The neutron-deficient nucleus Te-110 has been investigated by in-beam spectroscopic methods using the NORDBALL multi-detector array. Except for the energy of one level observed in alpha-decay, excited states in Te-110 were previously unknown. The level scheme constructed from gamma gamma-coincidence relationships is presented with tentative spin assignments up to I-pi = 21(-). Above spin 8(+) the yrast states have negative parity. They are most likely the members of a band predominantly based on the nu(h(11/2)g(7/2)) two-quasiparticle configuration. A band crossing is observed at I-pi approximate to 17(-). It is suggested to be caused by the alignment of two h(11/2) neutrons. The cranked shell model correctly predicts the spin alignment, but fails to reproduce the observed band crossing frequency, possibly because of octupole effects.
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| 40. |
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| 41. |
- Garnsworthy, A. B., et al.
(författare)
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Spectroscopy of Po-212 and At-213 using a He-8 radioactive beam and EXOGAM
- 2005
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Ingår i: Journal of Physics G. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 31:10, s. S1851-S1854
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Tidskriftsartikel (refereegranskat)abstract
- A beam of 28 MeV He-8 particles with an average intensity 2 x 10(5) ions s(-1), produced by the SPIRAL facility at GANIL, was used to initiate fusion-evaporation reactions in thick targets of Pb-201 and Bi-209. Excited states of Po-212 and At-213 were populated in (He-8,4n) reactions. The emitted gamma-rays were detected using the EXOGAM array composed of four Compton suppressed germanium Clover detectors in a close geometry configuration. Preliminary results show that Po-212 has been populated to high spin (I similar or equal to 14) with a significantly increased yield compared with our previous He-8 beam experiment. An apparently increased relative population of states up to 12(+) was observed compared with published results from a Pb-208(Be-9,alpha n)(212) Po reaction at 48 MeV. Evidence is presented for a previously unreported de-excitation pathway: 69 keV (13(-) -> 12(+)). States up to I-pi = (39/2(-)) have also been observed in At-213.
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| 42. |
- Gorgen, A, et al.
(författare)
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Quadrupole moments of wobbling excitations in Lu-163
- 2004
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 69:3
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Tidskriftsartikel (refereegranskat)abstract
- Lifetimes of states in the triaxial strongly deformed bands of Lu-163 have been measured with the Gammasphere spectrometer using the Doppler-shift attenuation method. The bands have been interpreted as wobbling-phonon excitations from the characteristic electromagnetic properties of the transitions connecting the bands. Quadrupole moments are extracted for the zero-phonon yrast band and, for the first time, for the one-phonon wobbling band. The very similar results found for the two bands suggest a similar intrinsic structure and support the wobbling interpretation. While the in-band quadrupole moments for the bands show a decreasing trend towards higher spin, the ratio of the interband to the in-band transition strengths remains constant. Both features can be understood by a small increase in triaxiality towards higher spin. Such a change in triaxiality is also found in cranking calculations, to which the experimental results are compared.
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| 43. |
- Gorska, M, et al.
(författare)
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Cd-98(48)50 : The two-proton-hole spectrum in Sn-100(50)50
- 1997
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 79:13, s. 2415-2418
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in Cd-98, two proton holes from Sn-100, were identified and studied for the first time, using in-beam spectroscopy with highly selective ancillary detectors. The structure of the (pi g(9/2))(-2) two-proton-hole spectrum below a T-1/2 = 0.48(16) mu s isomer is deduced and compared to shell-model predictions. A tentative I-pi = (8(+)) assignment, as suggested by systematics, yields a strongly reduced B(E2,8(+) --> 6(+)) = 0.44((+20)(-10)) W.u., corresponding to an effective proton charge of e(pi) = 0.85((+20)(-10))e, which is at variance with existing theoretical predictions.
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| 44. |
- Gorska, M, et al.
(författare)
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Spectroscopy of the T-z=1 nuclei close to Sn-100
- 1997
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Ingår i: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 28:1-2, s. 303-307
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Tidskriftsartikel (refereegranskat)abstract
- The two nuclei Cd-98 and Sn-102, closest neighbours of Sn-100, have been studied with a recoil catcher setup, following the reactions: Ni-58(Ti-46, alpha 2n)Cd-98 and Ni-58(Cr-50, alpha 2n)Sn-102. Long lived isomeric states were measured in Cd-98 I-pi = (8+), t(1/2) = 0.48(8) mu s and in Sn-102 I-pi = (6(+)) with t(1/2) = 1.0(6) mu s. The proposed experimental level schemes of the isomeric decay are presented and compared to the shell model predictions.
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| 45. |
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| 46. |
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| 47. |
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| 48. |
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| 49. |
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| 50. |
- Herskind, B., et al.
(författare)
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Charged particle feeding of hyperdeformed nuclei in the A=118-126 region
- 2006
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Ingår i: Physica Scripta. - 0031-8949 .- 1402-4896. ; T125, s. 108-114
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Tidskriftsartikel (refereegranskat)abstract
- A breakthrough was recently obtained in the analysis of the so-called Hyper-Long-HyperDeformed (HLHD) experiment made at the EUROBALL-IV gamma-detector array (EB). The Ni-64 + Ni-64 double right arrow Ba-128* fusion reaction was studied at E-beam = 255 and 261 MeV, reaching the highest angular momentum that the compound nuclei can accommodate. To date no discrete HD rotational bands have been identified. However, rotational patterns in the form of ridge-structures in three-dimensional (3D) rotational mapped spectra are identified with dynamic moments of inertia J((2)) ranging from 71 to 111h(2) MeV-1 in 12 different nuclei selected by charged particle- and/or gamma-gating. The four nuclei, Te-118, Cs-124, Cs-125 and Xe-124 found with moment of inertia J((2)) >= 100h(2) MeV-1, are most likely hyperdeformed, the remaining nuclei with smaller values of J((2)), are considered to be superdeformed, in qualitative agreement with recent theoretical calculations.
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