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  • Zouganelis, I., et al. (author)
  • The Solar Orbiter Science Activity Plan : Translating solar and heliospheric physics questions into action
  • 2020
  • In: Astronomy and Astrophysics. - : EDP SCIENCES S A. - 0004-6361 .- 1432-0746. ; 642
  • Journal article (peer-reviewed)abstract
    • Solar Orbiter is the first space mission observing the solar plasma both in situ and remotely, from a close distance, in and out of the ecliptic. The ultimate goal is to understand how the Sun produces and controls the heliosphere, filling the Solar System and driving the planetary environments. With six remote-sensing and four in-situ instrument suites, the coordination and planning of the operations are essential to address the following four top-level science questions: (1) What drives the solar wind and where does the coronal magnetic field originate?; (2) How do solar transients drive heliospheric variability?; (3) How do solar eruptions produce energetic particle radiation that fills the heliosphere?; (4) How does the solar dynamo work and drive connections between the Sun and the heliosphere? Maximising the mission's science return requires considering the characteristics of each orbit, including the relative position of the spacecraft to Earth (affecting downlink rates), trajectory events (such as gravitational assist manoeuvres), and the phase of the solar activity cycle. Furthermore, since each orbit's science telemetry will be downloaded over the course of the following orbit, science operations must be planned at mission level, rather than at the level of individual orbits. It is important to explore the way in which those science questions are translated into an actual plan of observations that fits into the mission, thus ensuring that no opportunities are missed. First, the overarching goals are broken down into specific, answerable questions along with the required observations and the so-called Science Activity Plan (SAP) is developed to achieve this. The SAP groups objectives that require similar observations into Solar Orbiter Observing Plans, resulting in a strategic, top-level view of the optimal opportunities for science observations during the mission lifetime. This allows for all four mission goals to be addressed. In this paper, we introduce Solar Orbiter's SAP through a series of examples and the strategy being followed.
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  • Arguedas Cuendis, S., et al. (author)
  • First results on the search for chameleons with the KWISP detector at CAST
  • 2019
  • In: Physics of the Dark Universe. - : Elsevier. - 2212-6864. ; 26
  • Journal article (peer-reviewed)abstract
    • We report on a first measurement with a sensitive opto-mechanical force sensor designed for the direct detection of coupling of real chameleons to matter. These dark energy candidates could be produced in the Sun and stream unimpeded to Earth. The KWISP detector installed on the CAST axion search experiment at CERN looks for tiny displacements of a thin membrane caused by the mechanical effect of solar chameleons. The displacements are detected by a Michelson interferometer with a homodyne readout scheme. The sensor benefits from the focusing action of the ABRIXAS X-ray telescope installed at CAST, which increases the chameleon flux on the membrane. A mechanical chopper placed between the telescope output and the detector modulates the incoming chameleon stream. We present the results of the solar chameleon measurements taken at CAST in July 2017, setting an upper bound on the force acting on the membrane of 80pN at 95% confidence level. The detector is sensitive for direct coupling to matter 104≤βm≤108, where the coupling to photons is locally bound to βγ≤1011.
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  • Elhai, M, et al. (author)
  • Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study
  • 2019
  • In: Annals of the rheumatic diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 78:7, s. 979-987
  • Journal article (peer-reviewed)abstract
    • To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical practice.MethodsWe performed a prospective study including patients with SSc from the European Scleroderma Trials and Research (EUSTAR) network treated with rituximab and matched with untreated patients with SSc. The main outcomes measures were adverse events, skin fibrosis improvement, lung fibrosis worsening and steroids use among propensity score-matched patients treated or not with rituximab.Results254 patients were treated with rituximab, in 58% for lung and in 32% for skin involvement. After a median follow-up of 2 years, about 70% of the patients had no side effect. Comparison of treated patients with 9575 propensity-score matched patients showed that patients treated with rituximab were more likely to have skin fibrosis improvement (22.7 vs 14.03 events per 100 person-years; OR: 2.79 [1.47–5.32]; p=0.002). Treated patients did not have significantly different rates of decrease in forced vital capacity (FVC)>10% (OR: 1.03 [0.55–1.94]; p=0.93) nor in carbon monoxide diffusing capacity (DLCO) decrease. Patients having received rituximab were more prone to stop or decrease steroids (OR: 2.34 [1.56–3.53], p<0.0001). Patients treated concomitantly with mycophenolate mofetil had a trend for better outcomes as compared with patients receiving rituximab alone (delta FVC: 5.22 [0.83–9.62]; p=0.019 as compared with controls vs 3 [0.66–5.35]; p=0.012).ConclusionRituximab use was associated with a good safety profile in this large SSc-cohort. Significant change was observed on skin fibrosis, but not on lung. However, the limitation is the observational design. The potential stabilisation of lung fibrosis by rituximab has to be addressed by a randomised trial.
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  • Becker, M, et al. (author)
  • Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis
  • 2019
  • In: Annals of the rheumatic diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 78:9, s. 1242-1248
  • Journal article (peer-reviewed)abstract
    • Mortality and worsening of organ function are desirable endpoints for clinical trials in systemic sclerosis (SSc). The aim of this study was to identify factors that allow enrichment of patients with these endpoints, in a population of patients from the European Scleroderma Trials and Research group database.MethodsInclusion criteria were diagnosis of diffuse SSc and follow-up over 12±3 months. Disease worsening/organ progression was fulfilled if any of the following events occurred: new renal crisis; decrease of lung or heart function; new echocardiography-suspected pulmonary hypertension or death. In total, 42 clinical parameters were chosen as predictors for the analysis by using (1) imputation of missing data on the basis of multivariate imputation and (2) least absolute shrinkage and selection operator regression.ResultsOf 1451 patients meeting the inclusion criteria, 706 had complete data on outcome parameters and were included in the analysis. Of the 42 outcome predictors, eight remained in the final regression model. There was substantial evidence for a strong association between disease progression and age, active digital ulcer (DU), lung fibrosis, muscle weakness and elevated C-reactive protein (CRP) level. Active DU, CRP elevation, lung fibrosis and muscle weakness were also associated with a significantly shorter time to disease progression. A bootstrap validation step with 10 000 repetitions successfully validated the model.ConclusionsThe use of the predictive factors presented here could enable cohort enrichment with patients at risk for overall disease worsening in SSc clinical trials.
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12.
  • Felipe, T., et al. (author)
  • Three-dimensional structure of a sunspot light bridge
  • 2016
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 596
  • Journal article (peer-reviewed)abstract
    • Context. Active regions are the most prominent manifestations of solar magnetic fields; their generation and dissipation are fundamental problems in solar physics. Light bridges are commonly present during sunspot decay, but a comprehensive picture of their role in the removal of the photospheric magnetic field is still lacking. Aims. We study the three-dimensional configuration of a sunspot, and in particular, its light bridge, during one of the last stages of its decay. Methods. We present the magnetic and thermodynamical stratification inferred from full Stokes inversions of the photospheric Si I 10 827 angstrom and Ca I 10 839 angstrom lines obtained with the GREGOR Infrared Spectrograph of the GREGOR telescope at the Observatorio del Teide, Tenerife, Spain. The analysis is complemented by a study of continuum images covering the disk passage of the active region, which are provided by the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory. Results. The sunspot shows a light bridge with penumbral continuum intensity that separates the central umbra from a smaller umbra. We find that in this region the magnetic field lines form a canopy with lower magnetic field strength in the inner part. The photospheric light bridge is dominated by gas pressure (high-beta), as opposed to the surrounding umbra, where the magnetic pressure is higher. A convective flow is observed in the light bridge. This flow is able to bend the magnetic field lines and to produce field reversals. The field lines merge above the light bridge and become as vertical and strong as in the surrounding umbra. We conclude that this occurs because two highly magnetized regions approach each other during the sunspot evolution.
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  • Joshi, Jayant, et al. (author)
  • Upper chromospheric magnetic field of a sunspot penumbra : observations of fine structure
  • 2016
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 596
  • Journal article (peer-reviewed)abstract
    • Aims. The fine-structure of the magnetic field in a sunspot penumbra in the upper chromosphere is to be explored and compared to that in the photosphere. Methods. Spectropolarimetric observations with high spatial resolution were recorded with the 1.5-m GREGOR telescope using the GREGOR Infrared Spectrograph (GRIS). The observed spectral domain includes the upper chromospheric Hei triplet at 10 830 angstrom and the photospheric Si I 10 827.1 angstrom and Ca I 10 833.4 angstrom spectral lines. The upper chromospheric magnetic field is obtained by inverting the Hei triplet assuming a Milne-Eddington-type model atmosphere. A height-dependent inversion was applied to the Si I 10 827.1 angstrom and Ca I 10 833.4 angstrom lines to obtain the photospheric magnetic field. Results. We find that the inclination of the magnetic field varies in the azimuthal direction in the photosphere and in the upper chromosphere. The chromospheric variations coincide remarkably well with the variations in the inclination of the photospheric field and resemble the well-known spine and interspine structure in the photospheric layers of penumbrae. The typical peak-to-peak variations in the inclination of the magnetic field in the upper chromosphere are found to be 10 degrees-15 degrees, which is roughly half the variation in the photosphere. In contrast, the magnetic field strength of the observed penumbra does not vary on small spatial scales in the upper chromosphere. Conclusions. Thanks to the high spatial resolution of the observations that is possible with the GREGOR telescope at 1.08 microns, we find that the prominent small-scale fluctuations in the magnetic field inclination, which are a salient part of the property of sunspot penumbral photospheres, also persist in the chromosphere, although at somewhat reduced amplitudes. Such a complex magnetic configuration may facilitate penumbral chromospheric dynamic phenomena, such as penumbral micro-jets or transient bright dots.
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  • Joshi, Jayant, et al. (author)
  • Vertical magnetic field gradient in the photospheric layers of sunspots
  • 2017
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 599
  • Journal article (peer-reviewed)abstract
    • Aims. We investigate the vertical gradient of the magnetic field of sunspots in the photospheric layer. Methods. Independent observations were obtained with the Solar Optical Telescope/Spectropolarimeter (SOT/SP) on board the Hinode spacecraft and with the Tenrife Infrared Polarimeter-2 (TIP-2) mounted at the German Vacuum Tower Telescope (VTT). We apply state-of-the-art inversion techniques to both data sets to retrieve the magnetic field and the corresponding vertical gradient along with other atmospheric parameters in the solar photosphere. Results. In the sunspot penumbrae we detected patches of negative vertical gradients of the magnetic field strength, i.e., the magnetic field strength decreases with optical depth in the photosphere. The negative gradient patches are located in the inner and partly in the middle penumbrae in both data sets. From the SOT/SP observations we found that the negative gradient patches are restricted mainly to the deep photospheric layers and are concentrated near the edges of the penumbral filaments. Magnetohydrodynamic (MHD) simulations also show negative gradients in the inner penumbrae, also at the locations of filaments. In the observations and the simulation negative gradients of the magnetic field vs. optical depth dominate at some radial distances in the penumbra. The negative gradient with respect to optical depth in the inner penumbrae persists even after averaging in the azimuthal direction in the observations and, to a lesser extent, in the MHD simulations. If the gradients in the MHD simulations are determined with respect to geometrical height, then the azimuthal averages are always positive within the sunspot (above log tau = 0), corresponding to magnetic field increasing with depth, as generally expected. Conclusions. We interpret the observed localized presence of negative vertical gradient of the magnetic field strength in the observations as a consequence of stronger field from spines expanding with height and closing above the weaker field inter-spines. The presence of the negative gradients with respect to optical depth after azimuthal averaging can be explained by two different mechanisms: the high corrugation of equal optical depth surfaces and the cancellation of polarized signal due to the presence of unresolved opposite polarity patches in the deeper layers of the penumbra.
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  • Sarakinos, Kostas, 1980-, et al. (author)
  • Unravelling the effect of nitrogen on the morphological evolution of thin silver films on weakly-interacting substrates
  • 2024
  • In: Applied Surface Science. - : Elsevier BV. - 0169-4332 .- 1873-5584. ; 649
  • Journal article (peer-reviewed)abstract
    • We study the effect of nitrogen on the morphological evolution of thin silver (Ag) films deposited on weakly-interacting amorphous carbon (a-C) and silicon oxide (SiOx) surfaces. Films are synthesized at a deposition rate of 0.1nm·s-1 by direct current magnetron sputtering (DCMS), high power impulse magnetron sputtering (HiPIMS), and electron-beam evaporation (EBE). We monitor growth in situ and in real time by measuring the evolution of film stress and optical properties, complemented by ex situ analyses of discontinuous-layer morphologies, film crystal structure, and film composition. We find that addition of molecular nitrogen (N2) to the plasmagenic gas (Ar) during DCMS and HiPIMS promotes a two-dimensional (2D) morphology. Concurrently, EBE-deposited films exhibit a significantly more pronounced three-dimensional morphological evolution, independently from the gas atmosphere composition. We argue that the 2D morphology in DCMS- and HiPIMS-grown films is enhanced due to incorporation of atomic nitrogen (N)—result of plasma-induced N2 dissociation—that hinders island reshaping during coalescence. This mechanism is not active during EBE due to the absence of energetic plasma electrons driving N2 dissociation. The overall results of the study show that accurate control of vapor-phase chemistry is of paramount importance when using gaseous species as agents for manipulating growth in weakly-interacting film-substrate systems.
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  • Wedemeyer, S., et al. (author)
  • Solar Science with the Atacama Large Millimeter/Submillimeter Array-A New View of Our Sun
  • 2016
  • In: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 200:1-4, s. 1-73
  • Research review (peer-reviewed)abstract
    • The Atacama Large Millimeter/submillimeter Array (ALMA) is a new powerful tool for observing the Sun at high spatial, temporal, and spectral resolution. These capabilities can address a broad range of fundamental scientific questions in solar physics. The radiation observed by ALMA originates mostly from the chromosphere-a complex and dynamic region between the photosphere and corona, which plays a crucial role in the transport of energy and matter and, ultimately, the heating of the outer layers of the solar atmosphere. Based on first solar test observations, strategies for regular solar campaigns are currently being developed. State-of-the-art numerical simulations of the solar atmosphere and modeling of instrumental effects can help constrain and optimize future observing modes for ALMA. Here we present a short technical description of ALMA and an overview of past efforts and future possibilities for solar observations at submillimeter and millimeter wavelengths. In addition, selected numerical simulations and observations at other wavelengths demonstrate ALMA's scientific potential for studying the Sun for a large range of science cases.
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  • Brehm, Nicolas, et al. (author)
  • Eleven-year solar cycles over the last millennium revealed by radiocarbon in tree rings
  • 2021
  • In: Nature Geoscience. - : Springer Science and Business Media LLC. - 1752-0894 .- 1752-0908. ; 14:1, s. 10-15
  • Journal article (peer-reviewed)abstract
    • The Sun provides the principal energy input into the Earth system and solar variability represents a significant external climate forcing. Although observations of solar activity (sunspots) cover only the last about 400 years, radionuclides produced by cosmic rays and stored in tree rings or ice cores serve as proxies for solar activity extending back thousands of years. However, the presence of weather-induced noise or low temporal resolution of long, precisely dated records hampers cosmogenic nuclide-based studies of short-term solar variability such as the 11-yr Schwabe cycle. Here we present a continuous, annually resolved atmospheric 14C concentration (fractionation-corrected ratio of 14CO2 to CO2) record reconstructed from absolutely dated tree rings covering nearly all of the last millennium (ad 969–1933). The high-resolution and precision 14C record reveals the presence of the Schwabe cycle over the entire time range. The record confirms the ad 993 solar energetic particle event and reveals two new candidates (ad 1052 and ad 1279), indicating that strong solar events that might be harmful to modern electronic systems probably occur more frequently than previously thought. In addition to showing decadal-scale solar variability over the last millennium, the high-temporal-resolution record of atmospheric radiocarbon also provides a useful benchmark for making radiocarbon dating more accurate over this interval.
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  • Bühler, David, et al. (author)
  • A comparison between solar plage and network properties
  • 2019
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 630
  • Journal article (peer-reviewed)abstract
    • Aims. We compare the properties of kG magnetic structures in the solar network and in active region plage at high spatial resolution.Methods. Our analysis used six SP scans of the solar disc centre aboard Hinode SOT and inverted the obtained spectra of the photospheric 6302 angstrom line pair using the 2D SPINOR code.Results. Photospheric magnetic field concentrations in network and plage areas are on average 1.5 kG strong with inclinations of 10 degrees-20 degrees, and have <400 m s(-1) internal and 2-3 km s(-1) external downflows. At the disc centre, the continuum intensity of magnetic field concentrations in the network are on average 10% brighter than the mean quiet Sun, whilst their plage counterparts are 3% darker. A more detailed analysis revealed that all sizes of individual kG patches in the network have 150 G higher field strengths on average, 5% higher continuum contrasts, and 800 m s(-1) faster surrounding downflows than similarly sized patches in the plage. The speed of the surrounding downflows also correlates with the patch area, and patches containing pores can produce supersonic flows exceeding 11 km s(-1) in individual pixels. Furthermore, the magnetic canopies of kG patches are on average 9 degrees more horizontal in the plage compared to the network.Conclusions. Most of the differences between the network and plage are due to their different patch size distributions, but the intrinsic differences between similarly sized patches likely results from the modification of the convection photospheric convection with increasing amounts of magnetic flux.
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  • Chauhan, Hetal R., et al. (author)
  • Role of micro- and nano-CeO 2 reinforcements on characteristics and tribological performance of HVOF sprayed Cr3C2-NiCr coatings
  • 2023
  • In: Surface and Coatings Technology. - 0257-8972 .- 1879-3347. ; 467
  • Journal article (peer-reviewed)abstract
    • The present study investigates the role of micro- and nano-CeO2 reinforcements on microstructural, mechanical and tribological properties of Cr3C2-NiCr coatings deposited using high-velocity-oxy-fuel (HVOF) spray process. A novel blending method involving ultrasonication, magnetic stirring and 3D-tumbler mixing was used to prepare the micro- and nano-CeO2 reinforced Cr3C2-NiCr feedstock powders. Unreinforced Cr3C2-NiCr coatings were also prepared for comparison purposes. X-ray diffraction, FE-SEM, EDS mapping, optical microscopy and optical profilometry were used to characterize the coatings. Tribological studies were performed on the coatings using modular ball-on-disc tribometer. The results showed that nano-CeO2 reinforced coatings yielded considerable reduction in porosity, surface roughness and CoF values while significantly enhancing the hardness and fracture toughness in comparison to the micro-CeO2 reinforced and unreinforced Cr3C2-NiCr coatings. The addition of nanoCeO2 to the coatings contributed to the microstructure refinement and to the formation of stable tribo-oxide layer, resulting in a lower specific wear rate under identical test conditions. Performance of micro-CeO2 reinforced coatings was intermediate to that of nano-CeO2 reinforced and unreinforced Cr3C2-NiCr coatings.
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  • Dongre, Mitesh, et al. (author)
  • Evidence on how a conserved glycine in the hinge region of HapR regulates its DNA binding ability : lessons from a natural variant.
  • 2011
  • In: Journal of Biological Chemistry. - 0021-9258 .- 1083-351X. ; 286:17, s. 15043-9
  • Journal article (peer-reviewed)abstract
    • HapR has been recognized as a quorum-sensing master regulator in Vibrio cholerae. Because it controls a plethora of disparate cellular events, the absence of a functional HapR affects the physiology of V. cholerae to a great extent. In the current study, we pursued an understanding of an observation of a natural protease-deficient non-O1, non-O139 variant V. cholerae strain V2. Intriguingly, a nonfunctional HapR (henceforth designated as HapR(V2)) harboring a substitution of glycine to aspartate at position 39 of the N-terminal hinge region has been identified. An in vitro gel shift assay clearly suggested the inability of HapR(V2) to interact with various cognate promoters. Reinstatement of glycine at position 39 restores DNA binding ability of HapR(V2) (HapR(V2G)), thereby rescuing the protease-negative phenotype of this strain. The elution profile of HapR(V2) and HapR(V2G) proteins in size-exclusion chromatography and their circular dichroism spectra did not reflect any significant differences to explain the functional discrepancies between the two proteins. To gain insight into the structure-function relationship of these two proteins, we acquired small/wide angle x-ray scattering data from samples of the native and G39D mutant. Although Guinier analysis and indirect Fourier transformation of scattering indicated only a slight difference in the shape parameters, structure reconstruction using dummy amino acids concluded that although HapR adopts a "Y" shape similar to its crystal structure, the G39D mutation in hinge drastically altered the DNA binding domains by bringing them in close proximity. This altered spatial orientation of the helix-turn-helix domains in this natural variant provides the first structural evidence on the functional role of the hinge region in quorum sensing-related DNA-binding regulatory proteins of Vibrio spp.
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  • Hoffman, Lindsey M., et al. (author)
  • Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG) : A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries
  • 2018
  • In: Journal of Clinical Oncology. - : AMER SOC CLINICAL ONCOLOGY. - 0732-183X .- 1527-7755. ; 36:19, s. 1963-1972
  • Journal article (peer-reviewed)abstract
    • PurposeDiffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median survival of < 1 year. The International and European Society for Pediatric Oncology DIPG Registries collaborated to compare clinical, radiologic, and histomolecular characteristics between short-term survivors (STSs) and long-term survivors (LTSs).Materials and MethodsData abstracted from registry databases included patients from North America, Australia, Germany, Austria, Switzerland, the Netherlands, Italy, France, the United Kingdom, and Croatia.ResultsAmong 1,130 pediatric and young adults with radiographically confirmed DIPG, 122 (11%) were excluded. Of the 1,008 remaining patients, 101 (10%) were LTSs (survival 2 years). Median survival time was 11 months (interquartile range, 7.5 to 16 months), and 1-, 2-, 3-, 4-, and 5-year survival rates were 42.3% (95% CI, 38.1% to 44.1%), 9.6% (95% CI, 7.8% to 11.3%), 4.3% (95% CI, 3.2% to 5.8%), 3.2% (95% CI, 2.4% to 4.6%), and 2.2% (95% CI, 1.4% to 3.4%), respectively. LTSs, compared with STSs, more commonly presented at age < 3 or > 10 years (11% v 3% and 33% v 23%, respectively; P < .001) and with longer symptom duration (P < .001). STSs, compared with LTSs, more commonly presented with cranial nerve palsy (83% v 73%, respectively; P = .008), ring enhancement (38% v 23%, respectively; P = .007), necrosis (42% v 26%, respectively; P = .009), and extrapontine extension (92% v 86%, respectively; P = .04). LTSs more commonly received systemic therapy at diagnosis (88% v 75% for STSs; P = .005). Biopsies and autopsies were performed in 299 patients (30%) and 77 patients (10%), respectively; 181 tumors (48%) were molecularly characterized. LTSs were more likely to harbor a HIST1H3B mutation (odds ratio, 1.28; 95% CI, 1.1 to 1.5; P = .002).ConclusionWe report clinical, radiologic, and molecular factors that correlate with survival in children and young adults with DIPG, which are important for risk stratification in future clinical trials.
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22.
  • Joshi, Jayant, et al. (author)
  • Three-dimensional magnetic structure of a sunspot : Comparison of the photosphere and upper chromosphere
  • 2017
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 604
  • Journal article (peer-reviewed)abstract
    • Aims. We investigate the magnetic field of a sunspot in the upper chromosphere and compare it to the photospheric properties of the field. Methods. We observed the main leading sunspot of the active region NOAA 11124 during two days with the Tenerife Infrared Polarimeter-2 (TIP-2) mounted at the German Vacuum Tower Telescope (VTT). Through inversion of Stokes spectra of the He i triplet at 10 830 angstrom, we obtained the magnetic field vector of the upper chromosphere. For comparison with the photosphere, we applied height-dependent inversions of the Si i 10 827.1 angstrom and Ca i 10 833.4 angstrom lines. Results. We found that the umbral magnetic field strength in the upper chromosphere is lower by a factor of 1.30-1.65 compared to the photosphere. The magnetic field strength of the umbra decreases from the photosphere toward the upper chromosphere by an average rate of 0.5-0.9Gkm 1. The difference in the magnetic field strength between both atmospheric layers steadily decreases from the sunspot center to the outer boundary of the sunspot; the field, in particular its horizontal component, is stronger in the chromopshere outside the spot and this is suggestive of a magnetic canopy. The sunspot displays a twist that on average is similar in the two layers. However, the differential twist between the photosphere and chromosphere increases rapidly toward the outer penumbral boundary. The magnetic field vector is more horizontal with respect to the solar surface by roughly 5-20 degrees in the photosphere compared to the upper chromosphere. Above a lightbridge, the chromospheric magnetic field is equally strong as that in the umbra, whereas the field of the lightbridge is weaker than its surroundings in the photosphere by roughly 1 kG. This suggests a cusp-like magnetic field structure above the lightbridge.
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23.
  • Jungclaus, Johann H., et al. (author)
  • The PMIP4 contribution to CMIP6 - Part 3 : The last millennium, scientific objective, and experimental design for the PMIP4 past1000 simulations
  • 2017
  • In: Geoscientific Model Development. - : Copernicus GmbH. - 1991-959X .- 1991-9603. ; 10:11, s. 4005-4033
  • Journal article (peer-reviewed)abstract
    • The pre-industrial millennium is among the periods selected by the Paleoclimate Model Intercomparison Project (PMIP) for experiments contributing to the sixth phase of the Coupled Model Intercomparison Project (CMIP6) and the fourth phase of the PMIP (PMIP4). The past1000 transient simulations serve to investigate the response to (mainly) natural forcing under background conditions not too different from today, and to discriminate between forced and internally generated variability on interannual to centennial timescales. This paper describes the motivation and the experimental set-ups for the PMIP4-CMIP6 past1000 simulations, and discusses the forcing agents orbital, solar, volcanic, and land use/land cover changes, and variations in greenhouse gas concentrations. The past1000 simulations covering the pre-industrial millennium from 850 Common Era (CE) to 1849 CE have to be complemented by historical simulations (1850 to 2014 CE) following the CMIP6 protocol. The external forcings for the past1000 experiments have been adapted to provide a seamless transition across these time periods. Protocols for the past1000 simulations have been divided into three tiers. A default forcing data set has been defined for the Tier 1 (the CMIP6 past1000) experiment. However, the PMIP community has maintained the flexibility to conduct coordinated sensitivity experiments to explore uncertainty in forcing reconstructions as well as parameter uncertainty in dedicated Tier 2 simulations. Additional experiments (Tier 3) are defined to foster collaborative model experiments focusing on the early instrumental period and to extend the temporal range and the scope of the simulations. This paper outlines current and future research foci and common analyses for collaborative work between the PMIP and the observational communities (reconstructions, instrumental data).
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25.
  • Przybylski, D., et al. (author)
  • Chromospheric extension of the MURaM code
  • 2022
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 664
  • Journal article (peer-reviewed)abstract
    • Context. Detailed numerical models of the chromosphere and corona are required to understand the heating of the solar atmosphere. An accurate treatment of the solar chromosphere is complicated by the effects arising from non-local thermodynamic equilibrium (NLTE) radiative transfer. A small number of strong, highly scattering lines dominate the cooling and heating in the chromosphere. Additionally, the recombination times of ionised hydrogen are longer than the dynamical timescales, requiring a non-equilibrium (NE) treatment of hydrogen ionisation.Aims. We describe a set of necessary additions to the MURaM code that allow it to handle some of the important NLTE effects. We investigate the impact on solar chromosphere models caused by NLTE and NE effects in radiation magnetohydrodynamic simulations of the solar atmosphere.Methods. The MURaM code was extended to include the physical process required for an accurate simulation of the solar chromosphere, as implemented in the Bifrost code. This includes a time-dependent treatment of hydrogen ionisation, a scattering multi-group radiation transfer scheme, and approximations for NLTE radiative cooling.Results. The inclusion of NE and NLTE physics has a large impact on the structure of the chromosphere; the NE treatment of hydrogen ionisation leads to a higher ionisation fraction and enhanced populations in the first excited state throughout cold inter-shock regions of the chromosphere. Additionally, this prevents hydrogen ionisation from buffering energy fluctuations, leading to hotter shocks and cooler inter-shock regions. The hydrogen populations in the ground and first excited state are enhanced by 102–103 in the upper chromosphere and by up to 109 near the transition region.Conclusions. Including the necessary NLTE physics leads to significant differences in chromospheric structure and dynamics. The thermodynamics and hydrogen populations calculated using the extended version of the MURaM code are consistent with previous non-equilibrium simulations. The electron number and temperature calculated using the non-equilibrium treatment of the chromosphere are required to accurately synthesise chromospheric spectral lines.
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26.
  • Schmidt, G. A., et al. (author)
  • Climate forcing reconstructions for use in PMIP simulations of the last millennium (v1.0)
  • 2011
  • In: Geoscientific Model Development. - : Copernicus GmbH. - 1991-959X .- 1991-9603. ; 4:1, s. 33-45
  • Journal article (peer-reviewed)abstract
    • Simulations of climate over the Last Millennium (850-1850 CE) have been incorporated into the third phase of the Paleoclimate Modelling Intercomparison Project (PMIP3). The drivers of climate over this period are chiefly orbital, solar, volcanic, changes in land use/land cover and some variation in greenhouse gas levels. While some of these effects can be easily defined, the reconstructions of solar, volcanic and land use-related forcing are more uncertain. We describe here the approach taken in defining the scenarios used in PMIP3, document the forcing reconstructions and discuss likely implications.
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27.
  • Schmidt, G. A., et al. (author)
  • Climate forcing reconstructions for use in PMIP simulations of the last millennium (v1.0)
  • 2010
  • In: Geoscientific Model Development. - : Copernicus GmbH. - 1991-959X. ; 3:3, s. 1549-1586
  • Journal article (peer-reviewed)abstract
    • Simulations of climate over the Last Millennium (850-1850 CE) have been incorporated into the third phase of the Paleoclimate Modelling Intercomparison Project (PMIP3). The drivers of climate over this period are chiefly orbital, solar, volcanic, changes in land use/land cover and some variation in greenhouse gas levels. While some of these effects can be easily defined, the reconstructions of solar, volcanic and land use-related forcing are more uncertain. We describe here the approach taken in defining the scenarios used in PMIP3, document the forcing reconstructions and discuss likely implications.
  •  
28.
  • Schmidt, G. A., et al. (author)
  • Climate forcing reconstructions for use in PMIP simulations of the Last Millennium (v1.1)
  • 2012
  • In: Geoscientific Model Development. - : Copernicus GmbH. - 1991-959X .- 1991-9603. ; 5:1, s. 185-191
  • Journal article (peer-reviewed)abstract
    • We update the forcings for the PMIP3 experiments for the Last Millennium to include new assessments of historical land use changes and discuss new suggestions for calibrating solar activity proxies to total solar irradiance.
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29.
  • Si, Peng, et al. (author)
  • Gold nanomaterials for optical biosensing and bioimaging
  • 2021
  • In: Nanoscale Advances. - : Royal Society of Chemistry. - 2516-0230. ; 3:10, s. 2679-2698
  • Research review (peer-reviewed)abstract
    • Gold nanoparticles (AuNPs) are highly compelling nanomaterials for biomedical studies due to their unique optical properties. By leveraging the versatile optical properties of different gold nanostructures, the performance of biosensing and biomedical imaging can be dramatically improved in terms of their sensitivity, specificity, speed, contrast, resolution and penetration depth. Here we review recent advances of optical biosensing and bioimaging techniques based on three major optical properties of AuNPs: surface plasmon resonance, surface enhanced Raman scattering and luminescence. We summarize the fabrication methods and optical properties of different types of AuNPs, highlight the emerging applications of these AuNPs for novel optical biosensors and biomedical imaging innovations, and discuss the future trends of AuNP-based optical biosensors and bioimaging as well as the challenges of implementing these techniques in preclinical and clinical investigations.
  •  
30.
  • Telloni, Daniele, et al. (author)
  • Linking Small-scale Solar Wind Properties with Large-scale Coronal Source Regions through Joint Parker Solar Probe-Metis/Solar Orbiter Observations
  • 2022
  • In: Astrophysical Journal. - : IOP Publishing Ltd. - 0004-637X .- 1538-4357. ; 935:2
  • Journal article (peer-reviewed)abstract
    • The solar wind measured in situ by Parker Solar Probe in the very inner heliosphere is studied in combination with the remote-sensing observation of the coronal source region provided by the METIS coronagraph aboard Solar Orbiter. The coronal outflows observed near the ecliptic by Metis on 2021 January 17 at 16:30 UT, between 3.5 and 6.3 R (circle dot) above the eastern solar limb, can be associated with the streams sampled by PSP at 0.11 and 0.26 au from the Sun, in two time intervals almost 5 days apart. The two plasma flows come from two distinct source regions, characterized by different magnetic field polarity and intensity at the coronal base. It follows that both the global and local properties of the two streams are different. Specifically, the solar wind emanating from the stronger magnetic field region has a lower bulk flux density, as expected, and is in a state of well-developed Alfvenic turbulence, with low intermittency. This is interpreted in terms of slab turbulence in the context of nearly incompressible magnetohydrodynamics. Conversely, the highly intermittent and poorly developed turbulent behavior of the solar wind from the weaker magnetic field region is presumably due to large magnetic deflections most likely attributed to the presence of switchbacks of interchange reconnection origin.
  •  
31.
  • van Noort, M., et al. (author)
  • A prototype of a microlensed hyperspectral imager for solar observations
  • 2022
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 668
  • Journal article (peer-reviewed)abstract
    • Context. When spectropolarimetric data are recorded at high spatial, spectral, and temporal resolution, the quality of the data is generally limited by the signal-to-noise ratio.Aims. We present a prototype of an integral field spectrograph for solar observations. This prototype overcomes the limitations of traditional solar instrumentation and captures the spectral information for all points in a given field of view without scanning, in order to optimize the efficiency and to minimize spectral and spatial crosstalk.Methods. The prototype was executed as a plug-in for the TRIPPEL spectrograph at the Swedish 1-meter Solar Telescope (SST) and uses an array of microlenses to shrink each image element, so that dark space is created in between. The light is then dispersed in this space, allowing for the independent detection of each spatio-spectral image element on a 2D detector.Results. The prototype was built and installed at the SST, yielding several good-quality data sets. These data sets were used to determine the imaging performance and efficiency of the prototype.Conclusions. Although the instrument required high-accuracy optics, the transparency of the prototype was found to be about 25%, and the straylight properties were found to be typical for spectrographic instruments.
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32.
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33.
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34.
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35.
  • Yelles Chaouche, L., et al. (author)
  • Spectropolarimetric Diagnostics at the Solar Photosphere near the Limb
  • 2009
  • In: <em>Solar Polarization 5</em>. - : Astronomical Society of the Pacific. ; , s. 189-
  • Conference paper (peer-reviewed)abstract
    • In the present work, we investigate the formation of Stokes profiles and spectro-polarimetric diagnostics in an active region plage near the limb. We use 3-D radiation-MHD simulations with unipolar fields of an average strength of 400 G, which is largely concentrated in flux tubes in which the field reaches typical kilo-Gauss values. We generate synthetic Stokes spectra by radiative transfer calculations, then we degrade the simulated Stokes signal to account for observational conditions. The synthetic data treated in this manner are compared with and found to roughly reproduce spectro-polarimetric high-resolution observations at μ=0.39 obtained by the SOUP instrument with the Swedish 1-m Solar Telescope at the beginning of 2006.
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