| 1. |
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| 2. |
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| 3. |
- Andersson, Annica, et al.
(författare)
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Paths to a sustainable food sector guided by LCA – exemplified by pork production
- 2014
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- To describe a more sustainable food sector, a supply chain approach is needed. Changing supply chains inevitably means that a range of attributes of the product and its system will change. This project will take on this challenge and deliver detailed descriptions of supply chains of six commodities from a Swedish region in 2012; Milk, cheese, beef, pork, chicken and bread. The set-up of the project was that experts on production along the supply chain design environmentally improved systems. The next step was to challenge the improvements considering their possible consequences on products and systems from different perspectives: food safety, sensory qualities, animal welfare, and consumer appreciation and (only for primary production) costs. The final supply chains were quantified by life cycle assessment (LCA), and they were again assessed from the perspectives mentioned above. Results will be generated during August 2014 and comprise both single-product LCA and region-wide impacts of the future scenarios.
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| 4. |
- Benatar, Michael, et al.
(författare)
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Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01) : a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial
- 2024
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Ingår i: Lancet Neurology. - : Elsevier. - 1474-4422 .- 1474-4465. ; 23:7, s. 687-699
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Tidskriftsartikel (refereegranskat)abstract
- Background: Amyotrophic lateral sclerosis is a progressive neurodegenerative disorder leading to muscle weakness and respiratory failure. Arimoclomol, a heat-shock protein-70 (HSP70) co-inducer, is neuroprotective in animal models of amyotrophic lateral sclerosis, with multiple mechanisms of action, including clearance of protein aggregates, a pathological hallmark of sporadic and familial amyotrophic lateral sclerosis. We aimed to evaluate the safety and efficacy of arimoclomol in patients with amyotrophic lateral sclerosis.Methods: ORARIALS-01 was a multinational, randomised, double-blind, placebo-controlled, parallel-group trial done at 29 centres in 12 countries in Europe and North America. Patients were eligible if they were aged 18 years or older and met El Escorial criteria for clinically possible, probable, probable laboratory-supported, definite, or familial amyotrophic lateral sclerosis; had an ALS Functional Rating Scale-Revised score of 35 or more; and had slow vital capacity at 70% or more of the value predicted on the basis of the participant's age, height, and sex. Patients were randomly assigned (2:1) in blocks of 6, stratified by use of a stable dose of riluzole or no riluzole use, to receive oral arimoclomol citrate 1200 mg/day (400 mg three times per day) or placebo. The Randomisation sequence was computer generated centrally. Investigators, study personnel, and study participants were masked to treatment allocation. The primary outcome was the Combined Assessment of Function and Survival (CAFS) rank score over 76 weeks of treatment. The primary outcome and safety were analysed in the modified intention-to-treat population. This trial is registered with ClinicalTrials.gov, NCT03491462, and is completed.Findings: Between July 31, 2018, and July 17, 2019, 287 patients were screened, 245 of whom were enrolled in the trial and randomly assigned. The modified intention-to-treat population comprised 239 patients (160 in the arimoclomol group and 79 in the placebo group): 151 (63%) were male and 88 (37%) were female; mean age was 57·6 years (SD 10·9). CAFS score over 76 weeks did not differ between groups (mean 0·51 [SD 0·29] in the arimoclomol group vs 0·49 [0·28] in the placebo group; p=0·62). Cliff's delta comparing the two groups was 0·039 (95% CI –0·116 to 0·194). Proportions of participants who died were similar between the treatment groups: 29 (18%) of 160 patients in the arimoclomol group and 18 (23%) of 79 patients in the placebo group. Most deaths were due to disease progression. The most common adverse events were gastrointestinal. Adverse events were more often deemed treatment-related in the arimoclomol group (104 [65%]) than in the placebo group (41 [52%]) and more often led to treatment discontinuation in the arimoclomol group (26 [16%]) than in the placebo group (four [5%]).Interpretation: Arimoclomol did not improve efficacy outcomes compared with placebo. Although available biomarker data are insufficient to preclude future strategies that target the HSP response, safety data suggest that a higher dose of arimoclomol would not have been tolerated.Funding: Orphazyme.
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| 5. |
- de Peppo, Giuseppe Maria, 1981, et al.
(författare)
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Human embryonic mesodermal progenitors highly resemble human mesenchymal stem cells and display high potential for tissue engineering applications.
- 2010
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Ingår i: Tissue engineering. Part A. - : Mary Ann Liebert Inc. - 1937-335X .- 1937-3341. ; 16:7, s. 2161-82
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Tidskriftsartikel (refereegranskat)abstract
- Adult stem cells, such as human mesenchymal stem cells (hMSCs), show limited proliferative capacity and, after long-term culture, lose their differentiation capacity and are therefore not an optimal cell source for tissue engineering. Human embryonic stem cells (hESCs) constitute an important new resource in this field, but one major drawback is the risk of tumor formation in the recipients. One alternative is to use progenitor cells derived from hESCs that are more lineage restricted but do not form teratomas. We have recently derived a cell line from hESCs denoted hESC-derived mesodermal progenitors (hES-MPs), and here, using genome-wide microarray analysis, we report that the process of hES-MPs derivation results in a significantly altered expression of hESC characteristic genes to an expression level highly similar to that of hMSCs. However, hES-MPs displayed a significantly higher proliferative capacity and longer telomeres. The hES-MPs also displayed lower expression of HLA class II proteins before and after interferon-gamma treatment, indicating that these cells may somewhat be immunoprivileged and potentially used for HLA-incompatible transplantation. The hES-MPs are thus an appealing alternative to hMSCs in tissue engineering applications and stem-cell-based therapies for mesodermal tissues.
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| 6. |
- Sonesson, Ulf, et al.
(författare)
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Paths to a sustainable food sector: integrated design and LCA of future food supply chains : the case of pork production in Sweden
- 2016
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Ingår i: The International Journal of Life Cycle Assessment. - : Springer Ferlag. - 0948-3349 .- 1614-7502. ; 21:5, s. 664-676
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To describe a more sustainable food sector, a supply chain approach is needed. Changing a supply chain inevitably means that various attributes of the product and its system will change. This project assumed this challenge and delivered detailed descriptions, life cycle assessment (LCA) evaluations, and consequence assessments of the supply chains of six commodities, i.e., milk, cheese, beef, pork, chicken, and bread, from a Swedish region. This paper presents results for the pork supply chain. Methods: In the project setup, experts on production along supply chains designed three scenarios for environmentally improved systems. These scenarios, i.e., the ecosystem, plant nutrients, and climate scenarios, were intended to address different clusters of environmental goals. The next step was to challenge these scenarios by considering their possible consequences for products and systems from the food safety, sensory quality, animal welfare, consumer appreciation, and (for primary production only) cost perspectives. This led to changes in production system design to prevent negative consequences. The final supply chains were quantified using LCA and were again assessed from the three perspectives. Results and discussion: The scenario design approach worked well, thoroughly and credibly describing the production systems. Assessment of consequences bolstered the credibility and quality of the systems and results. The LCA of pig production and smoked ham identified large potentials for improvement by implementing available knowledge: global warming potential (GWP) could be reduced 21–54 % and marine eutrophication by 14–45 %. The main reason for these improvements was improved productivity (approaching the best producers’ current performance), though dedicated measures were also important, resulting in increased nitrogen efficiency, more varied crop rotations for crop production and better production management, and improved animal health and manure management for animal production. Reduced post-farm wastage contributed as did reduced emissions from fertilizer production. Conclusions: The working approach applied was successful in integrating LCA research with food system production expertise to deliver results relevant to supply chain decision-makers. The consequence assessments brought considerable value to the project, giving its results greater credibility. By introducing constraints in the form of “no negative consequences and no increased costs,” the work was “guided” so that the scenario design avoided being hampered by too many opportunities.
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| 7. |
- Stenberg, Bo, et al.
(författare)
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Risk for N losses after harvest in tilled and untilled clays
- 2010
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Konferensbidrag (refereegranskat)abstract
- There have been indications that the increase of mineral N and increased risk of leaching that has been observed in light textured soils after early tillage in autumn should be as pronounced in heavier textured soils. The results of this study in 24 soils ranging from loam to clay indicate that mineralisation is similar independent of texture and that the risk for losses is similar. However, leaching could be a smaller problem in clays and the main mechanism for losses would instead be denitrification.
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| 8. |
- Stenberg, Gunilla, Med dr, 1968-, et al.
(författare)
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Gender matters in physiotherapy
- 2022
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Ingår i: Physiotherapy Theory and Practice. - : Taylor & Francis. - 0959-3985 .- 1532-5040. ; 38:13, s. 2316-2329
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Tidskriftsartikel (refereegranskat)abstract
- The World Health Organization states that gender has implications for health across the course of a person's life in terms of norms, roles and relations. It also has implications in rehabilitation. In this article, we argue the need of gender perspectives in the field of physiotherapy; gender matters and makes a difference in health and rehabilitation. We highlight a number of central areas where gender may be significant and give concrete examples of social gender aspects in physiotherapy practice and in diverse patient groups. We also discuss why it can be important to consider gender from an organizational perspective and how sociocultural norms and ideals relating to body, exercise and health are gendered. Further we present useful gender theories and conceptual frameworks. Finally, we outline future directions in terms of gender-sensitive intervention, physiotherapy education and a gendered application of the ICF model. We want to challenge physiotherapists and physiotherapy students to broaden knowledge and awareness of how gender may impact on physiotherapy, and how gender theory can serve as an analytical lens for a useful perspective on the development of clinical practice, education and research within physiotherapy.
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| 9. |
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| 10. |
- Wessén, Ella, et al.
(författare)
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Spatial distribution of ammonia-oxidizing bacteria and archaea across a 44-hectare farm related to ecosystem functioning
- 2011
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Ingår i: Isme Journal. - : Springer Science and Business Media LLC. - 1751-7362 .- 1751-7370. ; 5:7, s. 1213-1225
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Tidskriftsartikel (refereegranskat)abstract
- Characterization of spatial patterns of functional microbial communities could facilitate the understanding of the relationships between the ecology of microbial communities, the biogeochemical processes they perform and the corresponding ecosystem functions. Because of the important role the ammonia-oxidizing bacteria (AOB) and archaea (AOA) have in nitrogen cycling and nitrate leaching, we explored the spatial distribution of their activity, abundance and community composition across a 44-ha large farm divided into an organic and an integrated farming system. The spatial patterns were mapped by geostatistical modeling and correlations to soil properties and ecosystem functioning in terms of nitrate leaching were determined. All measured community components for both AOB and AOA exhibited spatial patterns at the hectare scale. The patchy patterns of community structures did not reflect the farming systems, but the AOB community was weakly related to differences in soil pH and moisture, whereas the AOA community to differences in soil pH and clay content. Soil properties related differently to the size of the communities, with soil organic carbon and total nitrogen correlating positively to AOB abundance, while clay content and pH showed a negative correlation to AOA abundance. Contrasting spatial patterns were observed for the abundance distributions of the two groups indicating that the AOB and AOA may occupy different niches in agro-ecosystems. In addition, the two communities correlated differently to community and ecosystem functions. Our results suggest that the AOA, not the AOB, were contributing to nitrate leaching at the site by providing substrate for the nitrite oxidizers. The ISME Journal (2011) 5, 1213-1225; doi:10.1038/ismej.2010.206; published online 13 January 2011 Subject Category: microbial ecology and functional diversity of natural habitats
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| 11. |
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| 12. |
- Andersson, Kristina, et al.
(författare)
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RISE Policylabb – de första fem åren
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In this report, we have compiled our learnings and experiences of working with Policy Lab. Policy Labs have come about as an answer to the question "Can you work with policy and regulatory development in a better way than today?". Our answer to the question is a yes. Our hope with the report is that others will become interested and start their own Policy Lab. Abroad, there are many Policy Labs, but in Sweden there are only a few, which is why we believe there is room for more. There is not a given way to work with Policy Labs once and for all, but each Policy Lab is unique based on its context. Sweden's innovation agency Vinnova defines Policy Labs as follows: "Policy Labs can be explained as a group of actors with different competencies who want to develop a regulatory framework. In the Policy Lab, they use a set of user-centric methods and competencies to test, experiment, and learn in policy development."1 In our Policy Lab, we have worked in various research projects to: 1. analyse challenges/problems that arise between innovations, technology, market, and regulations, 2. develop one or more workable solutions and 3. interact with relevant actors to determine the next steps. What distinguishes our Policy Lab is that we never “own” the issue or solution. We must therefore always work with other actors who can take the results further. Our goal is to enable and skill people. This means that for us it is important to work concretely with real problems and needs owners and preferably test different solutions. We focus on the here and now perspective and not on what the future will look like in 10 years. It is about taking the next step forward towards the future, not creating the best rule, but instead creating the next rule. We also work consistently agile and use design as a method for problem solving. This means that the way we organize our work in the Policy Lab is circular and not linear. When it comes to using design as a method for problem solving, we use the concepts of "design thinking" and "double diamond". For us, it is also important that the members of the Policy Lab have different backgrounds and skills depending on what is needed in the individual project....
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| 13. |
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| 14. |
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| 15. |
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| 16. |
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| 17. |
- Aronsson, Helena, et al.
(författare)
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Leaching of N, P and glyphosate from two soils after herbicide treatment and incorporation of a ryegrass catch crop
- 2011
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Ingår i: Soil Use and Management. - : Wiley. - 0266-0032 .- 1475-2743. ; 27, s. 54-68
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Tidskriftsartikel (refereegranskat)abstract
- During 2005-2007, studies were carried out in two field experiments in southwest Sweden with separately tile-drained plots on a sandy soil (three replicates) and on a clay soil (two replicates). The overall aim was to determine the effects of different cropping systems with catch crops on losses of N, P and glyphosate. Different times of glyphosate treatment of undersown ryegrass catch crops were examined in combination with soil tillage in November or spring. Drainage water was sampled continuously in proportion to water flow and analysed for N, P and glyphosate. Catch crops were sampled in late autumn and spring and soil was analysed for mineral N content. The yields of following cereal crops were determined. The importance of keeping the catch crop growing as long as possible in the autumn is demonstrated to decrease the risk of N leaching. During a year with high drainage on the sandy soil, annual N leaching was 26 kg/ha higher for plots with a catch crop killed with glyphosate in late September than for plots with a catch crop, while the difference was very small during 1 yr with less drainage. Having the catch crop in place during October was the most important factor, whereas the time of incorporation of a dead catch crop did not influence N leaching from either of the two soils. However, incorporation of a growing catch crop in spring resulted in decreased crop yields, especially on the clay soil. Soil type affected glyphosate leaching to a larger extent than the experimental treatments. Glyphosate was not leached from the sand at all, while it was found at average concentrations of 0.25 mu g/L in drainage water from the clay soil on all sampling occasions. Phosphorus leaching also varied (on average 0.2 and 0.5 kg/ha/yr from the sand and clay, respectively), but was not significantly affected by the different catch crop treatments.
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| 18. |
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| 19. |
- Bergkvist, Göran, et al.
(författare)
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Clover cover crops under-sown in winter wheat increase yield of subsequent spring barley-Effect of N dose and companion grass
- 2011
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Ingår i: Field Crops Research. - : Elsevier BV. - 0378-4290 .- 1872-6852. ; 120, s. 292-298
-
Tidskriftsartikel (refereegranskat)abstract
- Four two-year field trials, arranged in randomised split-plots, were carried out in southern Sweden with the aim of determining whether reduced N fertiliser dose in winter wheat production with spring under-sown clover cover crops, with or without perennial ryegrass in the seed mixture, would increase the clover biomass and hence the benefits of the cover crops in terms of the effect on the wheat crop, on a subsequent barley crop and on the risk of N leaching. Four doses of nitrogen (0, 60, 120 or 180 kg N ha(-1)) constituted the main plots and six cover crop treatments the sub-plots. The cover crop treatments were red clover (Trifolium pratense L). white clover (Trifolium repens L) and perennial ryegrass (Lolium perenne L.) in pure stands and in mixtures. The winter wheat (Triticum aestivum L.) was harvested in August and the cover crops were ploughed under in November. The risk of N leaching was assessed in November by measuring the content of mineral N in the soil profile (0-30, 30-90 cm). In the following year, the residual effects of the cover crops were investigated in spring barley (Hordeum distichon L) without additional N. Under-sowing of cover crops did not influence wheat yield, while reduced N fertiliser dose decreased yield and increased the clover content of the cover crops. When N was applied, the mixed cover crops were as effective in depleting soil mineral nitrogen as a pure ryegrass cover crop, while pure clover was less efficient. The clover content at wheat harvest as well as the amount of N incorporated with the cover crops had a positive correlation with barley yield. Spring barley in the unfertilised treatments yielded, on average, 1.9-2.4 Mg DM ha(-1) more in treatments with clover cover crops than in the treatment without cover crops. However, this positive effect decreased as the N dose to the preceding wheat crop increased, particularly when the clover was mixed with grass. (C) 2010 Elsevier B.V. All rights reserved.
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| 20. |
- Berglund, Leif, et al.
(författare)
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A Post-Analysis of the Introduction of the EU Directive 92/57/EEC in the Swedish Construction Industry
- 2022
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Ingår i: Buildings. - : MDPI. - 2075-5309. ; 12:10
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Tidskriftsartikel (refereegranskat)abstract
- The EU directive 92/57/EEC focuses on ensuring that health and safety-related matters are taken into consideration during every stage of construction-related work and has been introduced into the regulations of the member countries. In 2006, Sweden was tasked by the European Commission to clarify its implementation of the directive, including which management roles and responsibilities were to come into effect during both the planning and eventual execution of construction work—changes that ultimately were introduced into the national regulations in 2009. Focusing on the accident trends in the construction industry in the years immediately following these regulatory changes, we find that the new management roles and responsibilities had no apparent effect on the accident rates. Furthermore, we argue that there is a need to broaden the analysis regarding the implementation of the EU directive 92/57/EEC to also include nation-specific changes to health and safety management and policy. These qualitative studies should also include a dedicated focus on how changes to management structures and processes may affect the prevalence of occupational diseases specifically.
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| 21. |
- Berglund, Leif, et al.
(författare)
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Byggindustrins säkerhetspark - ett program för säkerhetskultur : Delrapport 1: Säkerhetskulturforskning inom byggindustrin
- 2020
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Denna rapport är en kunskapsöversikt som beskriver internationell forskning om säkerhetskultur och säkerhetsarbete i byggindustrin. I rapporten diskuteras inledningsvis hur säkerhetskultur kan förstås i relation till organisationskultur och att mycket av de distinktioner som görs inom säkerhetskulturforskningen inom byggbranschen är avhängig synen på kulturbegreppet. I den forskning som studerats i denna litteraturöversikt är det vanligt med en mer normativ ansats, dvs., den är inte neutral utan den syftar till säkerhet. Det verkar inte vara lika vanligt med säkerhetskultur-forskning som i grunden har en tolkande ansats och som ställer sig mer neutral till huruvida kulturen i sig alltid leder till en högre grad av säkerhet. Med en sådan ansats kan dock säkerhetskulturens olika delar i högre grad analyseras utan att vara upptagen med dess koppling till en normativ syn på säkerhetskultur. Med utgångpunkt i den tidigare forskningen ger vi slutligen förslag på ett antal aktiviteter som skulle kunna införlivas i säkerhetsparken som ett sätt att stärka dess säkerhetsfrämjande arbete.
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| 22. |
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| 23. |
- Berglund, Leif, et al.
(författare)
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Byggindustrins säkerhetspark – ett program för säkerhetskultur : Resultat och rekommendationer
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Den svenska byggindustrin har gjort stora satsningar de senaste åren för att öka medvetenheten om vikten av att arbeta säkert. En del i denna satsning är att Byggföretagen (före detta Sveriges Byggindustrier) har byggt en säkerhetspark, dvs. en anläggning där de som arbetar inom industrin utbildas om säkerhet och får möjlighet att gemensamt reflektera över säkerhetsrelaterade frågor.Vår forskargrupp vid Luleå tekniska universitet, har följt parkens etablering med syfte att undersöka hur frågor rörande säkerhetskultur kan och har integrerats i säkerhetsparkens aktiviteter. Projektet finns redovisat i tre rapporter. Den första är en kartläggning av internationell forskning inom området säkerhetskultur, säkerhetsarbete och säkerhetsträning och finns redovisad i Delrapport 1: Säkerhetskulturforskning inom byggindustrin (Berglund et al, 2020). Den andra redovisar en kartläggning och karaktärisering av vilka säkerhetsinitiativ och säkerhetskulturer som finns hos Sveriges byggindustriers medlemsföretag. Den studien har presenterats i Delrapport 2: Säkerhetsinitiativ och säkerhetskultur i svensk byggindustri (Berglund et al, 2021). I denna tredje rapport som vi kallar Resultat och rekommendationer, presenterar vi en samlad analys av parkens verksamhet och avslutar med ett antal förslag till hur säkerhetsparken kan utvecklas vidare. I rapporten kan vi konstatera att säkerhetsparken finns på plats och har verkat i drygt tre år. Den består av ett stort antal stationer eller scenarion där ett antal arbetsområden, arbetssituationer och arbetsmoment speglas. Ett besök inleds inomhus med en introduktion där det besökande företaget eller skolan ges en inledande beskrivning av parkens innehåll och syfte och där ett flertal frågeställningar introduceras och diskuteras. Därefter fortsätter besöket utomhus genom att man besöker ett antal stationer som är utformade enligt den pedagogiska principen ”se, höra, göra och reflektera”. Valet av stationer som besöks görs i samråd med handledare och med det besökande företaget. Dagen avslutas på samma sätt som den inleddes, inomhus, med reflektioner om lärdomar att ta med sig hem till det egna företaget. Parken fungerar också som en display av aktuell utveckling inom branschen, inte minst när det gäller nya verktyg, utrustning, material, arbetsmoment och liknande, allt med ett fokus på förbättrad arbetsmiljö och säkerhet. Säkerhetsparken besöks idag främst av byggföretag och byggelever men även av andra representanter från andra branscher. Vi har intervjuat nyckelpersoner med anknytning till parken och omdömen om parken och besöket har i huvudsak varit goda. Vår rapport avslutas med elva utvecklingsområden som vi tror kan bidra till att göra en bra verksamhet vid säkerhetsparken ännu bättre.1. Problematisera rådande säkerhetskulturer på fler ställen, kanske stationer eller i fler moment i anläggningen.2. Den pedagogiska modellen är bra och kan utnyttjas på fler ställen i anläggningen.3. Alla besök bör ha en tydlig och specifik företagsprofilering.4. Alla besökare ska ha en arbetsuppgift när de återvänder till företaget.5. Stationerna måste vara aktuella och spegla realistiska situationer.6. Säkerhetsparken bör vara ett centrum för lärande, utveckling och innovation.7. Säkerhetsparken kan vara ett skyltfönster för ny teknik och bra utrustning.8. Jämställdhetsfrågor bör integreras i säkerhetsparkens arbete.9. Ledningens betydelse för säkerhetskultur bör betonas.10.Säkerhetsparken kan bli en resurs för utbildning av utländsk arbetskraft.11.Säkerhetsparken bör dokumentera sina erfarenheter.
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| 24. |
- Berglund, Leif, et al.
(författare)
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Exploring safety culture research in the construction industry
- 2023
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Ingår i: Work. - : IOS Press. - 1051-9815 .- 1875-9270. ; 76:2, s. 549-560
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Despite numerous regulatory initiatives to improve health and safety in the construction industry, it still ranks as one of the most accident-prone industries worldwide. A dedicated focus on safety culture has been suggested as a complement to laws, regulations and management systems.OBJECTIVE: This article explores safety culture research conducted in the construction industry, with the aim to provide insight into the specific themes that tend to be in focus as well as what theoretical and methodological approaches that tend to be favored.METHODS: Searches in scientific databases were conducted twice. In a first attempt, searches resulted in 54 hits but only two articles fit the scope of the study. A revision of the search phrase resulted in 124 hits. Ultimately, 17 articles fit the scope of the study and were included. The content of the articles was analyzed and sorted thematically.RESULTS: The results show that four themes are prevalent in the existing literature: 1) unique challenges entail a need for situated applications, 2) models developed to operationalize safety culture, 3) measuring safety culture, and 4) safety management and leadership as key factors.CONCLUSION:Although research focusing on the construction industry has come to favor certain study designs and definitions of safety culture, further research may be enriched by broadening the theoretical and methodological perspectives. Specifically, researchers should conduct more in-depth qualitative studies that take the complexity of the industry into account, including the interpersonal relations between the actors involved.
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| 25. |
- Berglund, Leif, et al.
(författare)
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Occupational accidents in Swedish construction trades
- 2021
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Ingår i: International Journal of Occupational Safety and Ergonomics. - : Taylor & Francis. - 1080-3548 .- 2376-9130. ; 27:2, s. 552-561
-
Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study is to anazlye accidents occurring in the Swedish construction industry focusing specifically on the situation in the individual trades. The article includes all occupational accidents with at least one day of absence from work that were reported to the Swedish Social Insurance Agency for the year of 2016. The results, focusing on accident cause, injured body parts, as well as accidents per weekday, month and age, show that although the trades share commonalities regarding occupational accidents a number of trade-specific problem areas stand out. With this in mind, conclusions are drawn regarding the situation in each respective trade and suggestions are made for future studies focusing on accidents in construction industry trades.
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| 26. |
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| 27. |
- Berglund, Leif, et al.
(författare)
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Safety culture development in the construction industry : The case of a safety park in Sweden
- 2023
-
Ingår i: Heliyon. - : Elsevier. - 2405-8440. ; 9:9
-
Tidskriftsartikel (refereegranskat)abstract
- The problem of occupational accidents in the construction industry has necessitated a focus on proactive measures such as safety management programs. An example of this is safety parks, i.e. facilities where employees and managers from different construction companies can participate in site-specific activities and train in safety-related matters in a realistic context. Two specific focus areas are often present within these types of safety management programs: hands-on safety training and safety culture development as being within the purview of management. The purpose of this article is to investigate the developers’ intentions with the park in relation to safety culture development. Twenty interviews were conducted with experts in the area of health and safety. Results indicate that the safety park can contribute as a mirror for the companies own operations, with new information and knowledge of how work can be performed with safety being prioritized, to developing communication regarding safety-related matters, and finally the stations at the park may initiate a translation process as to how the lessons learned at the park can be applied to the participants’ own workplaces. All in all, the activities at the park can be said to be normative in nature, i.e. the developers seemingly have a desire to steer the safety culture development in a certain direction. There is a need for further research focusing on the concept of safety culture in these types of programs and, more broadly, in relation to its intended industry-wide effects.
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| 28. |
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| 29. |
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| 30. |
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| 31. |
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| 32. |
- Dahlberg, Karuna, 1979-, et al.
(författare)
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An endeavour for change and self-efficacy in transition : patient perspectives on postoperative recovery after bariatric surgery - a qualitative study
- 2022
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Ingår i: International Journal of Qualitative Studies on Health and Well-being. - : Taylor & Francis. - 1748-2623 .- 1748-2631. ; 17:1
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: Self-efficacy plays a role in the process of making lifestyle changes. After bariatric surgery, patients must adapt to several lifelong lifestyle changes. The aim of this study was to explore patients' experiences of recovery after bariatric surgery in those reporting low preoperative self-efficacy.METHODS: This qualitative inductive interview study included 18 participants. Individual interviews were conducted approximately one year after the surgery. Data were analysed using thematic analysis.RESULTS: The analysis identified one theme, and five subthemes describing recovery after bariatric surgery. Participants described being at a crossroads before surgery and having to make a change. After surgery, they had to learn to handle their new situation, which included getting to know their new body, handling thoughts about themselves, and managing social relations. To enhance their situation, support and information were essential. Social relations, support, successes, and challenges influenced their self-efficacy, and thoughts about adopting lifestyle changes, maintaining motivation, and handling setbacks.CONCLUSIONS: Recovery one year after bariatric surgery is an ongoing process that involves challenges encountered in lifestyle changes and physical and psychological transformations. Self-efficacy is not static and is influenced during the recovery process. Support and information are essential to enhance patient recovery after bariatric surgery.
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| 33. |
- Dahlberg, Karuna, 1979-, et al.
(författare)
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Incident self-harm after bariatric surgery : A nationwide registry-based matched cohort study
- 2023
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Ingår i: Clinical Obesity. - : John Wiley & Sons. - 1758-8103 .- 1758-8111. ; 13:3
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Tidskriftsartikel (refereegranskat)abstract
- The aims of this study were to evaluate the longitudinal risk of self-harm and the risk factors for self-harm after bariatric surgery in patients and control subjects without prior self-harm. This observational cohort study was based on prospectively registered data. Patients 18–70 years at time of surgery, body mass index (BMI) > 30 kg/m2, who underwent a primary Roux-en-Y gastric bypass (RYGB) procedure or a primary sleeve gastrectomy between 2007 and 2019 were considered for inclusion. All patients who met the inclusion criteria were matched 1:10 to the general population in Sweden (69 492 patients vs. 694 920 controls). After excluding patients and controls with previous self-harm, a self-harm event occurred in 1408 patients in the surgical group (incidence rate (IR) 3.54/1000 person-years, 95% confidence interval (CI) 3.36–3.73) versus in 3162 patients in the control group (IR 0.81/1000 person-years, 95% CI 0.78–0.84), with a hazard ratio (HR) of 4.38 (95% CI 4.11–4.66, p < .001). Median follow-up time was 6.1 years. Risk factors were younger age, lower BMI, cardiovascular, and chronic obstructive pulmonary disease, all aspects of psychiatric comorbidities (except neuropsychiatric disorder), lower socioeconomic status, RYGB, lower health-related quality of life, lower postoperative weight loss, and not attending postoperative follow-up visits. Self-harm is clearly higher after bariatric surgery than in the general population. A qualitative follow-up may be particularly important for patients at increased risk.
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| 34. |
- Dahlberg, Karuna, 1979-, et al.
(författare)
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The General Self-Efficacy Scale in a population planned for bariatric surgery in Sweden : a psychometric evaluation study
- 2022
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Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 12:11
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: This study psychometrically evaluated General Self-Efficacy (GSE) Scale in patients planned for bariatric surgery in Sweden.DESIGN: A cross-sectional psychometric study. The psychometric evaluation was guided by the COnsensus-based Standards for the selection of health status Measurement Instruments checklist for health-related reported-patient outcomes.SETTING: Three bariatric centres in Sweden.PARTICIPANTS: Adult patients≥18 years old scheduled for primary bariatric surgery (with sleeve gastrectomy or Roux-en-Y gastric bypass).PRIMARY AND SECONDARY MEASURES: Psychometric properties of the GSE.RESULTS: In total, 704 patients were included in the analysis. Mean values for GSE items were 2.9-3.4 and the mean GSE sum score was 31.4 (SD 4.7). There were no floor or ceiling effects. Cronbach's alpha was 0.89. Men reported a higher mean GSE than did women, that is, 31.2 (SD 4.8) for women versus 32.1 (SD 4.3) for men, p=0.03. Correlation coefficients were weak or negligible: GSE and mental component summary score of 36-Item Short Form Health Survey (SF-36)/RAND 36, r=0.18 (p<0.00); GSE and physical component summary score of SF-36/RAND 36, r=0.07 (p=0.138); GSE and obesity-related problem scale r=-0.15 (p=0.001) and GSE and level of education, r=0.04 (p=0.35). Confirmatory factor analysis indicated a one-factor construct with a satisfactory goodness of fit, that is, Comparative Fit Index=0.927, root mean square error of approximation=0.092 and standardised root mean square residual=0.045. The factor GSE explained almost half or over half of the variance of each item (0.45-0.75, p-values<0.001).CONCLUSIONS: The GSE scale is a valid and reliable scale that can be used to assess general self-efficacy in patients undergoing bariatric surgery.
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| 35. |
- Dahlin, Sigrun, et al.
(författare)
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Cutting regime affects the amount and allocation of symbiotically fixed N in green manure leys
- 2010
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Ingår i: Plant and Soil. - : Springer Science and Business Media LLC. - 0032-079X .- 1573-5036. ; 331, s. 401-412
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Tidskriftsartikel (refereegranskat)abstract
- Cutting strategy effect on N(2) fixation and distribution of fixed N above and below ground in red clover (Trifolium pratense L.) and mixed red clover/perennial ryegrass (Lolium perenne L.) green manure leys was quantified in field experiments including in situ mezotrons and microplots. Symbiotically fixed N in clover, transfer of fixed N to grass in the mixed stands and the fate of (15)N contained in mulch were estimated by isotope dilution. Below ground clover-derived N was estimated by leaf labelling. Total N(2) fixation was estimated by correcting fixed N in plant shoots with plant-derived N below ground and recycled N from mulch. The total N(2) fixation was larger in harvested and mulched stands (average 45 g m(-2)) than in the intact stands (32 g m(-2)). Of the fixed N, 53% (intact), 46% (harvested) and 60% (mulched) was found below ground. The average recycling of N in mulch was 21% and contributed 13.7% (pure clover) and 2.2% (mixed) of the clover N in the regrowth. Recycling of N did not decrease N(2) fixation in the mulched compared with harvested stands. The results indicate that cutting regime should be considered when estimating total amounts of N fixed by green manure leys.
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| 36. |
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| 37. |
- Dahlin, Sigrun, et al.
(författare)
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Effect of wood ash and crushed rock soil amendments on red clover growth and dinitrogen fixation
- 2017
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Ingår i: Agricultural and Food Science. - 1459-6067 .- 1795-1895. ; 26, s. 188-197
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Tidskriftsartikel (refereegranskat)abstract
- The fertiliser effect of adding wood ash or crushed rock to a low-fertility soil, compared with an unamended control, was assessed in a pot experiment with a perennial ryegrass-red clover mixture. Dinitrogen (N-2) fixation by the clover and translocation of fixed N to the grass were determined using N-15 natural abundance. The wood ash produced the highest accumulated clover biomass over two cuts, followed by the crushed rock. Chemical analyses suggested that the increase was due to K supply by the amendments. The wood ash also led to larger amounts of fixed N compared with the control. However, N-2 fixation was not increased as much as biomass amount, leading to dilution of plant N. There were minor or no treatment effects on mineralisation from soil N pools. This indicates that good-quality wood ash can be successfully used as a multi-element soil amendment to enhance clover growth on low-fertility soils.
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| 38. |
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| 39. |
- Dahlin, Sigrun, et al.
(författare)
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Mulch N recycling in green manure leys under Scandinavian conditions
- 2011
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Ingår i: Nutrient cycling in agroecosystems. - : Springer Science and Business Media LLC. - 1385-1314 .- 1573-0867. ; 91, s. 119-129
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Tidskriftsartikel (refereegranskat)abstract
- Nitrogen (N) recycling to the regrowth of mulched red clover (Trifolium pratense L.) and mulched mixed red clover/perennial ryegrass (Lolium perenne L.) leys was determined in field experiments during three consecutive years using (15)N-labelled shoot material. Nitrogen recycling was greater in the pure clover stands than in the mixed stands in the beginning of the growing season, but increased successively in the mixed stands so that it was similar (14-15.5%) in both stands at the end of the season. This recycling of N from the mulch led to increased biomass accumulation but did not alter stand composition in the mixed stands. Mulch-derived N was incorporated into the soil organic N in both pure clover and mixed stands which thus contributed to building up soil fertility. An approximately similar proportion of N remained unaccounted for in mulched pure clover and mixed stand leys and presumably represented gaseous losses. To exploit the benefits of green manure leys in the humid temperate zone while minimising the negative environmental impact, these should be harvested rather than mulched.
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| 40. |
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| 41. |
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| 42. |
- Delin, Sofia, et al.
(författare)
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Effect of nitrogen fertilization on nitrate leaching in relation to grain yield response on loamy sand in Sweden
- 2014
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Ingår i: European Journal of Agronomy. - : Elsevier BV. - 1161-0301 .- 1873-7331. ; 52, s. 291-296
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Tidskriftsartikel (refereegranskat)abstract
- High rates of nitrogen (N) fertilizer may increase N leaching with drainage, especially when there is no further crop response. It is often discussed whether leaching is affected only at levels that no longer give an economic return, or whether reducing fertilization below the economic optimum could reduce leaching further. To study nitrate leaching with different fertilizer N rates (0-135 kg N ha-1) and grain yield responses, field experiments in spring oats were conducted in 2007, 2008 and 2009 on loamy sand in south-west Sweden. Nitrate leaching was determined from nitrate concentrations in soil water sampled with ceramic suction cups and measured discharge at a nearby measuring station. The results showed that nitrate leaching per kg grain produced had its minimum around the economic optimum, here defined as the fertilization level where each extra kg of fertilizer N resulted in a 10 kg increase in grain yield (85% DM). There were no statistically significant differences in leaching between treatments fertilized below this level. However, N leaching was significantly elevated in some of the treatments with higher fertilization rates and the increase in nitrate leaching from increased N fertilization could be described with an exponential function. According to this function, the increase was less than 0.04 kg kg-1 fertilizer N at and below the economic optimum. Above this fertilization level, the nitrate leaching response gradually increased as the yield response ceased and the increase amounted to 0.1 and 0.5 kg kg-1 when the economic optimum was exceeded by 35 and 100 kg N ha-1, respectively. The economic optimum fertilization level depends on the price relationship between grain and fertilizer, which in Sweden can vary between 5:1 and 15:1. In other words, precision fertilization that provides no more or no less than a 10 kg increase in grain yield per kg extra N fertilizer can be optimal for both crop profitability and the environment. To predict this level already at fertilization is a great challenge, and it could be argued that rates should be kept down further to ensure that they are not exceeded due to overestimation of the optimum rate. However, the development of precision agriculture with new tools for prediction may reduce this risk.
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| 43. |
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| 44. |
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| 45. |
- Delin, Sofia, et al.
(författare)
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Nitratutlakning beroende på kvävegödslingsnivå och skörderespons i havre på en lätt jord
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Höga kvävegödslingsnivåer kan öka nitratutlakningen. Hur stor denna ökning blir hänger troligtvis samman med grödans kväveutnyttjande och gödslingens effekt på skörden. För att studera nitratutlakningen efter olika kvävegödslingsnivåer och skörderespons, anlades fältförsök i havre 2007, 2008 och 2009 på en sandjord utanför Skara i Västergötland. Nitratutlakningen bestämdes från nitratkoncentrationen i markvatten som provtogs med keramiska sugceller placerade på 80 cm djup samt från uppmätt avrinning vid en mätstation i närheten. Resultaten visade att ökningen i utlakning på grund av gödsling var obetydande så länge gödslingen gav en skörderespons på åtminstone 10 kg kärna (85% TS) per kg tillfört kväve. Över denna gödslingsnivånivå avtog skörderesponsen och nitratutlakningen ökade gradvis. Detta innebar att utlakningen per producerat kg havre var som minst runt denna nivå. Den ekonomiskt optimala kvävegivan beror på prisrelationen mellan gödsel och spannmål, vilken i Sverige vanligen varierar mellan 5 och 15. Med andra ord, precisionsgödsling som innebär 10 kg skördeökning per extra kg kvävegödsel kan vara optimal för ekonomin och ger samtidigt ingen ökad kväveutlakning.
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| 46. |
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| 47. |
- Engström, Lena, et al.
(författare)
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Organic winter oilseed rape response to N fertilisation and preceding agroecosystem
- 2014
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Ingår i: Field Crops Research. - : Elsevier BV. - 0378-4290 .- 1872-6852. ; 167, s. 94-101
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Tidskriftsartikel (refereegranskat)abstract
- Increased knowledge on how to use organic amendments will increase crop productivity in organic farming. The effect of autumn and spring application of organic fertilisers on the yield of organic winter oilseed rape (WOR) with various preceding crops was studied at eight organic farm sites in southern Sweden in 2008/2009 and 2009/2010, in a two-factor experiment. Autumn N fertilisation (F1) comprised Biofer, applied at 0 and 50 kg N ha(-1), and spring N fertilisation (F2) comprised increasing rates of Vinasse (0, 50, 100, 150, 200 kg N ha(-1)). How soil mineral N, N uptake in late autumn and early spring, plant-available soil N during spring and summer (soilN(plant)) and yield level was associated with economically optimum N fertilisation rate (OptN) in spring was investigated. Autumn N application (Biofer) only increased yield by 140-410 kg ha(-1) at three sites, when there was a risk of low plant-available soil N during spring and summer, due to dry weather conditions or N immobilisation in soil caused by residues of previous grass ley crops. Nitrogen fertilisation during autumn cannot be recommended due to the high levels of soil mineral N in late autumn and risk for N leaching. Spring N fertilisation (Vinasse) can be recommended when the preceding crop is a grass ley, as yield increases were the highest, 820-1400 kg ha(-1). Spring N fertilisation had no impact on yield and cannot be recommended when the preceding crop is pasture or clover, providing that N uptake during autumn is great and/or if N availability in soil during spring and summer is not likely to be limited by e.g. dry weather conditions and weeds. Regression analysis confirmed that plant-available soil N was associated with OptN rate in spring and showed that factors such as soil mineral N, N uptake in late autumn, SoilN(plant) and yield level must be considered when estimating spring N fertilisation. (C) 2014 Elsevier B.V. All rights reserved.
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| 48. |
- Engström, Lena, et al.
(författare)
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Reducing nitrate leaching after winter oilseed rape and peas in mild and cold winters
- 2011
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Ingår i: Agronomy for Sustainable Development. - : Springer Science and Business Media LLC. - 1774-0746 .- 1773-0155. ; 31, s. 337-347
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Tidskriftsartikel (refereegranskat)abstract
- Nitrate leaching after winter oilseed rape and peas has not been studied at the most northern limits of oilseed rape cultivation where winters vary between being mild, with continuous drainage, and cold, with periods of frozen soil. Here, we studied the effect of N fertilisation to oilseed rape, catch crops after oilseed rape and peas and dired drilling of winter wheat after oilseed rape on N leaching in south-west Sweden. Nitrate leaching was determined in two field experiments, dated 2004-2006 and 2005-2007, respectively, on a sandy loam. Our results show that under oilseed rape nitrate leaching was low, at 16-23 kg N ha(-1), in a mild winter with drainage from October to March. In the subsequent mild winter nitrate leaching under wheat was higher, amounting to 35-94 kg N ha(-1). Nitrate leaching levels were similar, 32-58 kg N ha(-1), for all crops in a cold winter with a long-lasting snow cover and main drainage occurring after snowmelt in March and April. Application of fertiliser N to oilseed rape at the optimum N rate, rather than 50 kg N ha(-1) above optimum, reduced leaching in a following winter wheat crop by 25 and 27 kg N ha(-1) in a cold and a mild winter, respectively. Spring undersowing of perennial ryegrass as a catch crop reduced leaching by 12 kg N ha(-1) after optimally fertilised oilseed rape in a mild winter, despite only growing until mid-September when winter wheat was sown. An undersown catch crop of peas, then grown until November, reduced leaching by 15 kg N ha(-1). Direct drilling of winter wheat after oilseed rape had no effect. These findings show that there are risks of enhanced leaching in early spring after a cold winter with a snow cover and superficially frozen soil. Optimising the spring N rate for oilseed rape was the most effective measure to decrease leaching in both mild and cold winters, and this effect was improved by an undersown catch crop in a mild winter.
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| 49. |
- Enwall, Karin, et al.
(författare)
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Soil Resources Influence Spatial Patterns of Denitrifying Communities at Scales Compatible with Land Management
- 2010
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Ingår i: Applied and Environmental Microbiology. - 0099-2240 .- 1098-5336. ; 76, s. 2243-2250
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Tidskriftsartikel (refereegranskat)abstract
- Knowing spatial patterns of functional microbial guilds can increase our understanding of the relationships between microbial community ecology and ecosystem functions. Using geostatistical modeling to map spatial patterns, we explored the distribution of the community structure, size, and activity of one functional group in N cycling, the denitrifiers, in relation to 23 soil parameters over a 44-ha farm divided into one organic and one integrated crop production system. The denitrifiers were targeted by the nirS and nirK genes that encode the two mutually exclusive types of nitrite reductases, the cd(1) heme-type and copper reductases, respectively. The spatial pattern of the denitrification activity genes was reflected by the maps of the abundances of nir genes. For the community structure, only the maps of the nirS community were related to the activity. The activity was correlated with nitrate and dissolved organic nitrogen and carbon, whereas the gene pools for denitrification, in terms of size and composition, were influenced by the soil structure. For the nirS community, pH and soil nutrients were also important in shaping the community. The only unique parameter related to the nirK community was the soil Cu content. However, the spatial pattern of the nirK denitrifiers corresponded to the division of the farm into the two cropping systems. The different community patterns, together with the spatial distribution of the nirS/nirK abundance ratio, suggest habitat selection on the nirS-and nirK-type denitrifiers. Our findings constitute a first step in identifying niches for denitrifiers at scales relevant to land management.
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| 50. |
- Figueiredo, Margarida L. A., et al.
(författare)
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Non-coding roX RNAs prevent the binding of the MSL-complex to heterochromatic regions
- 2014
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Ingår i: PLOS Genetics. - : Public Library of Science (PLoS). - 1553-7390 .- 1553-7404. ; 10:12, s. e1004865-
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Tidskriftsartikel (refereegranskat)abstract
- Long non-coding RNAs contribute to dosage compensation in both mammals and Drosophila by inducing changes in the chromatin structure of the X-chromosome. In Drosophila melanogaster, roX1 and roX2 are long non-coding RNAs that together with proteins form the male-specific lethal (MSL) complex, which coats the entire male X-chromosome and mediates dosage compensation by increasing its transcriptional output. Studies on polytene chromosomes have demonstrated that when both roX1 and roX2 are absent, the MSL-complex becomes less abundant on the male X-chromosome and is relocated to the chromocenter and the 4thchromosome. Here we address the role of roX RNAs in MSL-complex targeting and the evolution of dosage compensation in Drosophila. We performed ChIP-seq experiments which showed that MSL-complex recruitment to high affinity sites (HAS) on the X-chromosome is independent of roX and that the HAS sequence motif is conserved in D. simulans. Additionally, a complete and enzymatically active MSL-complex is recruited to six specific genes on the 4thchromosome. Interestingly, our sequence analysis showed that in the absence of roX RNAs, the MSL-complex has an affinity for regions enriched in Hoppel transposable elements and repeats in general. We hypothesize that roX mutants reveal the ancient targeting of the MSL-complex and propose that the role of roX RNAs is to prevent the binding of the MSL-complex to heterochromatin.
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