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| 2. |
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| 3. |
- Dawson, Andreas, et al.
(författare)
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Dopamine in plasma : a biomarker for myofascial TMD pain?
- 2016
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Ingår i: Journal of Headache and Pain. - : Springer. - 1129-2369 .- 1129-2377. ; 17:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Dopaminergic pathways could be involved in the pathophysiology of myofascial temporomandibular disorders (M-TMD). This study investigated plasma levels of dopamine and serotonin (5-HT) in patients with M-TMD and in healthy subjects. METHODS: Fifteen patients with M-TMD and 15 age- and sex-matched healthy subjects participated. The patients had received an M-TMD diagnosis according to the Research Diagnostic Criteria for TMD. Perceived mental stress, pain intensity (0-100-mm visual analogue scale), and pressure pain thresholds (PPT, kPa) over the masseter muscles were assessed; a venous blood sample was taken. RESULTS: Dopamine in plasma differed significantly between patients with M-TMD (4.98 ± 2.55 nM) and healthy controls (2.73 ± 1.24 nM; P < 0.01). No significant difference in plasma 5-HT was observed between the groups (P = 0.75). Patients reported significantly higher pain intensities (P < 0.001) and had lower PPTs (P < 0.01) compared with the healthy controls. Importantly, dopamine in plasma correlated significantly with present pain intensity (r = 0.53, n = 14, P < 0.05) and perceived mental stress (r = 0.34, n = 28, P < 0.05). CONCLUSIONS: The results suggest that peripheral dopamine might be involved in modulating peripheral pain. This finding, in addition to reports in other studies, suggests that dopaminergic pathways could be implicated in the pathophysiology of M-TMD but also in other chronic pain conditions. More research is warranted to elucidate the role of peripheral dopamine in the pathophysiology of chronic pain.
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| 4. |
- Dzidic, Majda, et al.
(författare)
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Oral microbiome development during childhood: an ecological succession influenced by postnatal factors and associated with tooth decay
- 2018
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Ingår i: The ISME Journal. - : NATURE PUBLISHING GROUP. - 1751-7362 .- 1751-7370. ; 12:9, s. 2292-2306
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Tidskriftsartikel (refereegranskat)abstract
- Information on how the oral microbiome develops during early childhood and how external factors influence this ecological process is scarce. We used high-throughput sequencing to characterize bacterial composition in saliva samples collected at 3, 6, 12, 24 months and 7 years of age in 90 longitudinally followed children, for whom clinical, dietary and health data were collected. Bacterial composition patterns changed through time, starting with "early colonizers", including Streptococcus and Veillonella; other bacterial genera such as Neisseria settled after 1 or 2 years of age. Dental caries development was associated with diverging microbial composition through time. Streptococcus cristatus appeared to be associated with increased risk of developing tooth decay and its role as potential biomarker of the disease should be studied with species-specific probes. Infants born by C-section had initially skewed bacterial content compared with vaginally delivered infants, but this was recovered with age. Shorter breastfeeding habits and antibiotic treatment during the first 2 years of age were associated with a distinct bacterial composition at later age. The findings presented describe oral microbiota development as an ecological succession where altered colonization pattern during the first year of life may have long-term consequences for childs oral and systemic health.
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| 5. |
- Havsed, Kristian, et al.
(författare)
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Bacterial Composition and Metabolomics of Dental Plaque From Adolescents
- 2021
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Ingår i: Frontiers in Cellular and Infection Microbiology. - : Frontiers Media SA. - 2235-2988. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Supragingival dental plaque samples were collected from 40 Swedish adolescents, including 20 with caries lesions (CAR) and 20 caries-free (CF). Fresh plaque samples were subjected to an ex vivo acid tolerance (AT) test where the proportion of bacteria resistant to an acid shock was evaluated through confocal microscopy and live/dead staining, and the metabolites produced were quantified by 1H Nuclear Magnetic Resonance (1H NMR). In addition, DNA was extracted and the 16S rRNA gene was sequenced by Illumina sequencing, in order to characterize bacterial composition in the same samples. There were no significant differences in AT scores between CAR and CF individuals. However, 7 out of the 10 individuals with highest AT scores belonged to the CAR group. Regarding bacterial composition, Abiotrophia, Prevotella and Veillonella were found at significantly higher levels in CAR individuals (p=0.0085, 0.026 and 0.04 respectively) and Rothia and Corynebacterium at significantly higher levels in CF individuals (p=0.026 and 0.003). The caries pathogen Streptococcus mutans was found at low frequencies and was absent in 60% of CAR individuals. Random-forest predictive models indicate that at least 4 bacterial species or 9 genera are needed to distinguish CAR from CF adolescents. The metabolomic profile obtained by NMR showed a significant clustering of organic acids with specific bacteria in CAR and/or high AT individuals, being Scardovia wiggsiae the species with strongest associations. A significant clustering of ethanol and isopropanol with health-associated bacteria such as Rothia or Corynebacterium was also found. Accordingly, several relationships involving these compounds like the Ethanol : Lactate or Succinate : Lactate ratios were significantly associated to acid tolerance and could be of predictive value for caries risk. We therefore propose that future caries risk studies would benefit from considering not only the use of multiple organisms as potential microbial biomarkers, but also their functional adaptation and metabolic output.
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| 6. |
- Havsed, Kristian, et al.
(författare)
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Salivary proteins and metabolites as Caries Biomarkers in adolescents
- 2024
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Ingår i: Caries Research. - : S. Karger. - 0008-6568 .- 1421-976X.
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: The identification of salivary molecules that can be associated to dental caries could provide insights about caries risk and offer valuable information to develop caries prediction models. However, the search for a universal caries biomarker has proven elusive due to the multifactorial nature of this oral disease. We have therefore performed a systematic effort to identify caries-associated metabolites and proteins in saliva samples from adolescents that had a caries experience and those that were caries-free.METHODS: Quantification of approximately 100 molecules was performed by the use of a wide range of techniques, ranging from NMR metabolomics to ELISA, Luminex or colorimetric assays, as well as clinical features like plaque accumulation and gingival index. In addition, simplified dietary and oral hygiene habits questionnaires were also obtained.RESULTS: The caries-free group had significantly lower consumption of sweetened beverages and higher toothbrushing frequency. Surprisingly, very few compounds were found to individually provide discriminatory power between Caries-experienced and Caries-Free individuals. The data analysis revealed several potential reasons that could underly this lack of association value with caries, including differences in metabolite concentrations throughout the day, a lack of correlation between metabolite concentrations in plaque and saliva, or sex-related differences, among others. However, when multiple compounds were combined by multivariate analysis and random forest modelling, a combination of 3-5 compounds were found to provide good prediction models for morning (with an AUC accuracy of 0.87) and especially afternoon samples (AUC=0.93).CONCLUSION: While few salivary biomarker could differentiate between caries-free and caries-experienced adolescents, a combination of markers proved effective, particularcly in afternoon samples. To predict caries risk, these biomarkers should be validated in larger cohorts and longitudinal settings, considering factors such as gender differences, and variations in oral hygiene and diet.
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| 7. |
- Jiang, Nan, et al.
(författare)
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Effects of an integrated supportive program on xerostomia and saliva characteristics in patients with head and neck cancer radiated with a low dose to the major salivary glands : a randomized controlled trial
- 2022
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Ingår i: BMC Oral Health. - : BioMed Central. - 1472-6831. ; 22:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Xerostomia and changes in saliva characteristics are common side-effects in patients with head and neck cancer (HNC) undergoing radiotherapy, which negatively impact their oral health. However, there are no consensus standards for intervention to manage these problems. The aim of this study was to determine the effect of an integrated supportive program on xerostomia and saliva characteristics at a 1-year follow-up of patients with HNC radiated with a low dose to the major salivary glands.METHODS: The CONSORT guidelines for a randomized controlled trial were used. Participants with a low overall dose to major salivary glands were randomly allocated to an intervention group (n = 47) or a control group (n = 45). The intervention group received usual care and an integrated supportive program, which included three steps: face-to-face education; face-to-face coaching at 1 month post-radiotherapy; and four telephone coaching sessions at 2, 3, 6, and 9 months post-radiotherapy. The face-to-face education consisted of oral hygiene instruction, oral self-care strategies, facial and tongue muscle exercises, and salivary gland massage. Adherence to the intervention was evaluated using a questionnaire completed during the 9 months follow-up. The control group received usual care. The unstimulated saliva flow rate and xerostomia were assessed in both groups.RESULTS: A total of 79 participants (40 in the intervention group and 39 in the control group) completed the 12 months follow-up. The intervention group achieved significantly greater relief from xerostomia than the control group after 3 months (intervention group: 35.1 ± 5.9 versus control group: 38.0 ± 5.9, P = 0.027) and 12 months follow-up (intervention group: 18.5 ± 4.1 versus control group: 22.8 ± 4.3, P < 0.001). A higher unstimulated saliva flow rate was observed in the intervention group than the control group at 12 months follow-up (intervention group: 0.16 ± 0.08 versus control group: 0.12 ± 0.07, P = 0.035). Adherence to the intervention was generally good.CONCLUSION: This integrated supportive program with good adherence relieved xerostomia and had a positive effect on unstimulated saliva flow rate among patients with HNC radiated with a low dose to the major salivary glands during the 12 months of follow-up.TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2100051876 (08/10/2021), retrospectively registered.
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| 8. |
- Jiang, Nan
(författare)
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Radiation-Induced Xerostomia in Chinese Patients with Head and Neck Cancer – An Explorative and Interventional study
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Background: Radiation-induced xerostomia is a common oral complication of patients with head and neck cancer (HNC) undergoing radiotherapy (RT). This can lead to a series of functional oral disorders, particularly dental caries, and ultimately negatively affect their oral health and health-related quality of life (HRQoL).Aims: The overall aim of this thesis was to understand the living experience of radiation-induced xerostomia and to determine the effects of an integrated supportive program based on multicomponent oral care strategies in Chinese patients with HNC.Methods: A qualitative descriptive study was conducted to describe how patients (13 men and 7 women) with HNC experienced radiation-induced xerostomia (Ⅰ). A cross-sectional study of patients (n=80) with HNC was conducted to accomplish the validation of the Chinese version of the xerostomia questionnaire (XQ) (Ⅱ). A randomized controlled trial (n=79) was conducted to determine the effect of an integrated supportive program (with a combination of face-to-face health education and coaching sections) on xerostomia, saliva characteristics (Ⅲ), oral health, and HRQoL (IV).Results: Five categories emerged from the manifest content of the interviews: communication problems, physical problems, psychosocial problems, treatment problems, and relief strategies. The meaning underlying these categories formed a theme, which was the latent content of the interview: Due to lack of information regarding xerostomia, patients had to find their own ways to deal with the problem (Ⅰ). The Chinese version of XQ was a unidimensional scale (1-factor solution explained 75.6 of the total variance) and had good psychometric properties with excellent internal consistency (Cronbach’s α of 0.95), test-retest reliability (intraclass correlation coefficient of 0.92), and good criterion-related validity and content validity (Ⅱ). The integrated supportive program showed significant inter-group differences in xerostomia (P=0.046), unstimulated saliva flow rate (P=0.035), plaque index (P=0.038), Oral Health Impact Profile-14 (P=0.002), and Functional Assessment Cancer Therapy-Head & Neck (P=0.001) over the 12-month follow-up, with better outcomes in the intervention group (Ⅲ & Ⅳ).Conclusion: This thesis contributes knowledge regarding the experiences of living with xerostomia from a patient perspective, noting that xerostomia has a profound impact on a patient's physical, psychological, and social quality of life. There is lack of assessment tools for xerostomia in the Chinese population, and the Chinese version of XQ proved to be a valid and simple self-administered tool to measure and monitor the xerostomia level in patients with HNC. The integrated supportive program with multicomponent oral care strategies demonstrated positive effects on relieving xerostomia, increasing unstimulated saliva flow rate, and improving their oral health and HRQoL. These findings provide a basis for improvement in the management of xerostomia and oral health of Chinese patients with HNC through the integration of oral care in nursing.
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| 9. |
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| 10. |
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| 11. |
- Jiang, Nan, et al.
(författare)
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The effects of an integrated supportive programme on oral health in patients with head and neck cancer undergoing radiotherapy : A randomized controlled trial
- 2024
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Ingår i: International Journal of Dental Hygiene. - : John Wiley & Sons. - 1601-5029 .- 1601-5037.
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: This study determines the effect of an integrated 12-month follow-up support programme on the oral health of patients with head and neck cancer (HNC) who received radiotherapy (RT).METHODS: Participants were randomly assigned to an intervention group (n = 47) or a control group (n = 45). The intervention group received usual care and an integrated supportive programme, which included face-to-face education and telephone coaching. The control group received usual care. After a clinical dental examination, the prevalence of caries, gingival inflammation and plaque were registered. Oral health impact profile (OHIP)-14 and the WHO Oral Health Questionnaire for Adults were used to evaluate oral health in both groups.RESULTS: A total of 79 participants completed a 12-month follow-up. The intervention group had lower caries increment between baseline and the 12-month follow-up compared with controls, although this was not statistically significant. After 12 months, the intervention group had statistically significant better outcomes in the plaque index (p = 0.038) and the OHIP-14 (p = 0.002) than the control group. No statistically significant differences were found between the two groups concerning gingival index. However, the intervention group reported an overall better state of teeth (p = 0.034) and gums after 12 months (p = 0.042).CONCLUSIONS: The integrated supportive programme showed positive effects on improving oral health in patients with HNC regarding plaque control, the state of teeth and gums and oral health-related quality of life during the 12-month follow-up.
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| 12. |
- Karlsson, Frida, et al.
(författare)
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Caries incidence and risk assessment during a five-year period in adolescents living in south-eastern Sweden
- 2020
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Ingår i: International Journal of Dental Hygiene. - : Wiley-Blackwell. - 1601-5029 .- 1601-5037. ; 18:1, s. 92-98
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The aim was to examine the caries incidence in adolescents using the Public Dental Service (PDS) during a 5-year period in relation to their caries experience at baseline and risk classification.METHODS: A five-year retrospective cohort study based of the dental records from 17 PDS clinics in southeastern Sweden was conducted; 159 individuals born in 1997 were included, and their caries risk was classified at 12 and 17 years of age. Caries prevalence and documented risk groups were assessed at baseline and after five years.RESULTS: The increment of caries (both initial and manifest caries) was higher, to a statistically significant degree, after five years in adolescents who were recorded as caries-free at baseline compared to individuals with caries at baseline (p<0.001). In individuals with caries at baseline, the greatest increment of caries was found at approximal sites (p<0.001). At baseline, individuals were classified as low (94%), medium (6%) and high risk (0%). After five years, the figures were 74%, 20% and 6%, respectively. Although classified in a low-caries-risk group, 9% had ≥ 6 decayed or filled surfaces at baseline, and 23% did after five years. Approximately 62% of individuals were registered as caries-free at baseline, and 45% were after five years.CONCLUSIONS: There was an increase in caries over five years, especially among adolescents without caries experience at baseline. The majority of adolescents had the same risk classification after five years. Further research with a larger sample size is needed to evaluate risk assessment for caries.
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| 13. |
- Kvarnvik, Christine, et al.
(författare)
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Clinical and radiographic periodontal status in hypertensive patients with or without obstructive sleep apnea 10 years after diagnosis and CPAP initiation
- 2024
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Ingår i: Clinical and Experimental Dental Research. - : John Wiley & Sons. - 2057-4347. ; 10:2
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: Through inflammation and hyposalivation, obstructive sleep apnea (OSA) is suggested to affect periodontal status over time. Our aim was to compare the clinical and radiographic periodontal status of hypertensive patients with or without long-term presence of OSA, treated or untreated with continuous positive airway pressure treatment (CPAP).MATERIALS AND METHODS: In 2007-2009, a screening for OSA was conducted among 394 hypertensive primary care patients. Polygraphy was used to create three groups: no OSA, non-CPAP, or adherent CPAP based on the apnea hypopnea index (AHI). After 10 years, a cross-sectional sleep and periodontal examination including a clinical and radiographic examination, a questionnaire, and a matrix metalloproteinase-8 (MMP-8) chair-side test was conducted. Based on levels of alveolar bone, bleeding on probing (BoP), and probing pocket depth (PPD), patients were categorized into four periodontal stages: periodontal health/gingivitis and three periodontal disease stages. Periodontal status and periodontal stages were compared between the OSA (n = 49), non-CPAP (n = 38), or adherent CPAP (n = 34) groups.RESULTS: The 121 patients (53% women) had a median age of 71 years. No differences were seen between the OSA groups regarding median number of teeth (p = .061), teeth/implants, (p = .107), plaque index (p = .245), BoP (p = .848), PPD ≥ 4 mm (p = .561), PPD ≥ 6 mm (p = .630), presence of MMP-8 (p = .693) except for bone loss (p = .011). Among patients with stage periodontal health/gingivitis a significant difference was seen, as 70% of those were categorized as no OSA, 20% as non-CPAP, and 10% as adherent CPAP (p = .029). Differences were not seen in periodontal disease stages.CONCLUSIONS: Hypertensive patients with obstructive sleep apnea (OSA) did not have an adverse clinical periodontal status compared to patients without OSA. However, when combining radiographic and clinical status into periodontal stages, patients without OSA more frequently exhibited periodontal health or gingivitis compared to patients without OSA, regardless of CPAP treatment.
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| 14. |
- Moberg Sköld, Ulla, et al.
(författare)
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Astma hos barn och ungdomar : preventionsstrategier för karies och dental erosion
- 2023
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Ingår i: Tandläkartidningen. - : Tandläkartidningen. - 0039-6982. ; :5, s. 48-58
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Tidskriftsartikel (refereegranskat)abstract
- Astma och karies är två vanligt förekommande sjukdomar hos barn och ungdomar, och det finns samband mellan sjukdomarna och även mellan astma och dental erosion. En fungerande samverkan mellan barnhälsovården och tandvården är därför viktig så att tandvården tidigt kan sätta in adekvata preventionsstrategier, och vid behov ställa diagnos och behandla eventuell karies och dental erosion.
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| 15. |
- Moberg Sköld, Ulla, 1948, et al.
(författare)
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Risk factors for and prevention of caries and dental erosion in children and adolescents with asthma
- 2022
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Ingår i: Journal of Dental Sciences. - : Elsevier BV. - 1991-7902. ; 17:3, s. 1387-1400
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Forskningsöversikt (refereegranskat)abstract
- There are many studies and reviews of the relationship between the asthma disease in young individuals on the one hand and caries and dental erosion on the other. The causes of caries and dental erosion might be related to the asthmatic drugs, low pH and the sweeteners that the inhaled drug contains and perhaps even the lifestyle of children and adolescents with asthma. The main focus of this review is therefore to describe various preventive strategies, based on long experience of preventive dental care in Sweden. Two fact boxes are presented, one on fluoride toothpaste as a population-based intervention for different ages and one on diet counselling in children and adolescents with asthma. The most important thing is to introduce fluoride toothpaste early in the child's life and that the parents brush the child's teeth twice a day, in the morning after breakfast and at night before bedtime, up to the age of 10. Moreover, a high-risk approach with an additional fluoride supply at home is presented, together with the application of fluoride varnish at the clinic. Regarding diet counselling, it is important to make sure that the child has regular meals during the day, maximum five to six times a day, to allow the teeth to rest between meals and restrict sweets and soft drinks to once a week. It is important to identify children and adolescents with asthma as early as possible and to refer them to a dental team for preventive treatment.
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| 16. |
- Møller Christensen, Berit, et al.
(författare)
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Developing communication support for interaction with children during acute radiographic procedures
- 2020
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Ingår i: Radiography. - : Elsevier. - 1078-8174 .- 1532-2831. ; 26:2, s. 96-101
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: The Convention on the Rights of the Child will be absorbed into Swedish law by 2020, which highlights the need to promote equality in communication between health care professionals and communicatively vulnerable children. In this regard, participation and person-centredness is important in the interaction with each child to provide adequate information on the peri-radiographic process in a way that the child can understand. Hence, the aim was to develop communication support for interaction with children during acute radiographic procedures.Method: The study has a qualitative design adapting a multiphase structure. A participatory design was used which included four phases conducted in succession to each other. Interviews were conducted with children from Elementary School and Special School. Questionnaires were collected from their parents and from radiographers in four different Radiology Departments.Results: The analysis of the data highlighted the need for information in the peri-radiographic process. Parents and children wanted material that is easy to use and could be adapted in a person-centred way.Conclusion: A prototype of the ICIR (interactive communication support in radiology settings), with illustrations and accompanying text was developed that can be useful as information sharing in interaction between children, parents and health care professionals in the radiographic context.Implications for practice: The ICIR can be a usable tool for information sharing in the interaction between children, parents and health care professionals during radiographic procedures.
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| 17. |
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| 18. |
- Samuelsson, Niclas
(författare)
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Astma ökar risken för hål i tänderna
- 2021
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Ingår i: Allergia. - : Riksförbundet mot allergi. ; :4, s. 32-32
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Ingress: Studier visar att det finns ett samband mellan astma och problem med tänderna. Orsakerna till detta är flera och mer forskning i ämnet behövs.Personer med astma har ökad risk att utveckla karies i såväl mjölktänderna som i de permanenta tänderna. Det går dock inte att säga att det är astman i sig som orsakar karies, utan det kan ha att göra med flera olika faktorer, säger Malin Stensson, tandhygienist och universitetslektor vid Hälsohögskolan i Jönköping.
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| 19. |
- Shimada, Akiko, et al.
(författare)
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Differential effects of repetitive oral administration of monosodium glutamate on interstitial glutamate concentration and muscle pain sensitivity
- 2015
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Ingår i: Nutrition (Burbank, Los Angeles County, Calif.). - : Elsevier. - 0899-9007 .- 1873-1244. ; 31:2, s. 315-323
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to determine the relationship of high daily monosodium glutamate (MSG) consumption with glutamate concentrations in jaw muscle, saliva, and serum, and muscle pain sensitivity in healthy participants. Methods: A randomized, double-blinded, placebo-controlled study was conducted to investigate the effect of repetitive consumption of high-dose MSG on glutamate concentration in the masseter muscles measured by microdialysis and muscle pain sensitivity. In five contiguous experimental daily sessions, 32 healthy participants drank MSG (150 mg/kg) or NaCl (24 mg/kg) diluted with a 400 mL soda. The concentrations of glutamate before and after the ingestion were assessed in dialysate and plasma samples on the first and last days. Saliva glutamate concentration was assessed every day. Pressure pain threshold, pressure pain tolerance, autonomic parameters (heart rate, systolic and diastolic blood pressures) and reported side effects also were assessed. Results: No significant change was noted in the baseline concentration of glutamate in the masseter muscle, blood, or saliva, but the peak concentration in the masseter muscle increased significantly between day 1 and 5. A statistically significant increase in systolic and diastolic blood pressures after MSG administration was observed, as well as a significantly higher frequency of reports of nausea and headache in the MSG group. No robust effect of MSG on muscle sensitivity was found. Conclusion: Interstitial glutamate concentration in the masseter muscle is not highly disturbed by excessive repetitive intake of MSG in healthy man. (C) 2015 Elsevier Inc. All rights reserved.
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| 20. |
- Shmarina, Elena, et al.
(författare)
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Oral health literacy among migrant mothers in Sweden : A qualitative study
- 2023
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Ingår i: Acta Odontologica Scandinavica. - : Taylor & Francis. - 0001-6357 .- 1502-3850.
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveThis interview study explored the oral health literacy of migrant mothers in Sweden, with special reference to where and why they access information about oral health and how they determine the credibility of such information.Material and methodIn-depth interviews were conducted with seven migrant mothers of children up to 10 years old. The mothers had entered Sweden from 2015 onwards and had been resettled in Kalmar County, Sweden. Their native language was Somalian, Dari or Arabic. The interview questions concerned the participants’ experiences of seeking oral health information, as well as oral health in general and dental health services. The interviews were analysed by qualitative content analysis.FindingsThe main findings indicate that migrant mothers used information sourcing as a pathway to solve oral health literacy tasks. Three main categories were identified, each with subcategories, describing the migrant mothers’ experiences of accessing and evaluating oral health information: ‘accessible source of information’, ‘needs-related purpose of seeking information’ and ‘trustworthiness assessment’. The migrant mothers reported that in case of a dental emergency or general queries, they sought oral health information from professionals and social sources. Moreover, they perceived oral health information to be most reliable when it was provided by dental professionals, was a recurring theme, or constituted majority opinion.ConclusionTo improve oral health literacy in migrant mothers of young children, it is important not only to provide consistent and recurrent oral health information through accessible information channels, but also to adapt dental care to be more culturally appropriate.
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| 21. |
- Snögren, Maria, et al.
(författare)
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Psychometric evaluation of a short-form version of the Swedish "Attitudes to and Knowledge of Oral Health" questionnaire
- 2022
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Ingår i: BMC Geriatrics. - : Springer Science and Business Media LLC. - 1471-2318. ; 22:1
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Tidskriftsartikel (refereegranskat)abstract
- Background Healthcare professionals' attitudes to and knowledge of oral health are fundamental to providing good oral health care to older adults. One instrument that assesses healthcare professionals' attitudes to and knowledge of oral health in a Swedish context is the "Attitudes to and Knowledge of Oral health" (AKO) questionnaire. Two of the three item-groups of the AKO have previously been validated in a Swedish context. However, it is crucial that all three item-groups are validated, and beneficial to design a shorter, easy-to-use questionnaire for healthcare professionals while maintaining adequate integrity of its reliability and validity. Therefore, the present study aims to develop a short-form version of AKO and to secure its psychometric properties. Methods Psychometric evaluation with Classical Test Theory and Item Response Theory to validate and shorten AKO with 611 healthcare professionals from a population of 1159 working in a municipality in an urban area in western Sweden. Results Of the original 16 items in the AKO, 13 were shown to warrant retention in the abbreviated/shortened form. These showed acceptable validity and reliability for assessing healthcare professionals' attitudes to and knowledge of oral health. Conclusion This validated short-form version of AKO shows acceptable validity and reliability after being reduced to 13 items, structured in a 3-part scale. The items are consistent with the total scale, indicating that the internal consistency is acceptable. Future studies should be performed to evaluate AKO in other groups of healthcare professionals, across cultures, languages, and so on, to investigate its use and strengthen its validity and reliability.
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| 22. |
- Stensson, Malin, 1970-, et al.
(författare)
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Caries prevalence, caries-realted factors and plaque pH in adolescents with long-term asthma
- 2010
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Ingår i: Caries Research. - Karger : S. Karger AG. - 0008-6568 .- 1421-976X. ; 44:6, s. 540-546
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the present case-control study was to investigate dental caries, various caries-related factors as well as gingival condition, in 12- to 16-year-olds with long-term asthma (n = 20) and a matched healthy control group (n = 20). Data on dietary and oral hygiene habits, numbers of mutans streptococci and lactobacilli in saliva were also obtained. The plaque pH drop after a sucrose rinse was measured up to 40 min at 2 approximal tooth sites. A lower salivary flow rate was found in the asthma group compared to the control group (p < 0.05). The mean (± SD) of DFS, including manifest and initial caries, was 4.9 ± 5.5 in the asthma and 1.4 ± 2.3 (p < 0.01) in the control group. Only 1 adolescent in the asthma group was caries free compared to 13 in the control group. Concerning pH in plaque, adolescents with asthma had a lower initial value (p < 0.01) and final pH (p < 0.05) than the control group. The Cariogram data showed that 55% of the subjects in the control group had ‘a high chance of avoiding caries’ compared to 10% in the asthma group (p < 0.01). The asthmatic adolescents had higher numbers of sites with gingival bleeding (p < 0.01). To conclude, adolescents with long-term asthma had a higher total DFS and caries risk (according to Cariogram), decreased salivary rate, more gingival bleeding and lower plaque pH than adolescents without asthma.
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| 23. |
- Stensson, Malin, 1970-, et al.
(författare)
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Dental health care for children with Down syndrome : Parents' description of their children's needs in dental health care settings.
- 2022
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Ingår i: European Journal of Oral Sciences. - : John Wiley & Sons. - 0909-8836 .- 1600-0722. ; 130:3
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Tidskriftsartikel (refereegranskat)abstract
- A visit to the dental clinic may be challenging for a child with Down syndrome due to medical and oral health problems as well as communication problems. The aim of the present study was to explore how parents of children with Down syndrome describe their child's needs in the dental health care setting. In a survey concerning parental experiences with dental health care in Sweden, free comments were analysed with content analysis and resulted in five categories: "Need for continuity of care in dental health care"; "Need for dental health care professionals to have knowledge and expertise in caring for children with Down syndrome and other disabilities"; "Need for dental health care professionals to use a caring approach with children with Down syndrome"; "Need for the child with Down syndrome to be prepared to participate in their dental health care visit" and "Need for the child with Down syndrome to be given the same rights as typically developing children". To support children with Down syndrome in an optimal way, dental health care needs to be tailored to meet the child's unique needs. In addition, dental health care professionals need knowledge of and expertise in the care of children with Down syndrome.
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| 24. |
- Stensson, Malin, 1970-, et al.
(författare)
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Dental health care for children with Down syndrome – parents’ description of their children’s needs in dental health care settings
- 2023
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Konferensbidrag (refereegranskat)abstract
- A visit to the dental clinic may be challenging for a child with Downs syndrome due to medical and oral health problems as well as communication problems.Aim: The aim of the present study was to explore how parents of children with Down syndrome describe their child’s needs in the dental health care setting.Method: In a online survey concerning parental experiences with dental health care in Sweden, free comments were analysed with content analysis. By answering the survey, parents consented to participate. Ethical approval was obtained by from the Regional Ethics Committee for Human Research at Linköping University, Sweden.Result: The analyse resulted in five categories: “Need for continuity of care in dental health care”; “Need for dental health care professionals to have knowledge and expertise in caring for children with Down syndrome and other disabilities”; “Need for dental health care professionals to use a caring approach with children with Down syndrome”; “Need for the child with Down syndrome to be prepared to participate in their dental health care visit” “Need for the child with Down syndrome to be given the same rights as typically developing children”.Conclusion: To support children with Down syndrome in an optimal way, dental health care needs to be tailored to meet the child’s unique needs. When visiting dental health care services, children with Downs syndrome need continuity, and they need to meet professionals who have a caring approach and knowledge and experience of children with Down syndrome.
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| 25. |
- Stensson, Malin, 1970, et al.
(författare)
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On Oral Health in Young People with Asthma
- 2010
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Objective. The aim of this thesis was to investigate the oral health of young individuals with and without asthma. Material. In Study I, a group of 3- (n=66) and 6-year-old children (n=61) with asthma and two healthy control groups (n=62 and n=55 respectively) participated. In Study II, 3-year-old children with asthma (n=64) and a healthy control group (n=50) were followed from 3 to 6 years of age. In Study III, adolescents with severe and long-term asthma (n=20) and a healthy control group (n=20) were included. In Study IV, young adults with long-term asthma (n=20) and a healthy control group (n=20) participated. Methods. A clinical examination was performed and the prevalence of caries, gingival inflammation, plaque and the numbers of mutans streptococci and lactobacilli in saliva were determined. In Study II, the caries increment between 3 and 6 years of age was investigated. A radiographic examination was conducted in all the studies, apart from in the 3-year-old children. The participants or their parents were interviewed regarding various oral health-related factors. To assess the caries risk, a computer program, the “Cariogram”, was used. In Studies III and IV, the salivary secretion rate and plaque pH, after a sucrose rinse for up to 40 min at two approximal sites, were measured. In Study IV, gingival crevicular fluid, periodontal pockets and the plaque formation rate were determined. Results. In Study I, the mean ± SD dfs in the 3-year-olds with asthma was 1.4±3.2 compared with 0.5±1.2 in the control group (p<0.05). The corresponding figures for the 6-year-olds were 2.5±3.9 and 1.8±2.8 (NS). The 3-year-old children with asthma had more gingival bleeding than the healthy controls (p<0.05). Children with asthma reported a higher consumption of sugar-containing drinks and were more frequently mouth breathers than the control groups (p<0.05). Children with asthma and an immigrant background had a higher mean dfs than children with an immigrant background in the control group. In the follow-up study (Study II), the increment of initial caries was higher for children with asthma compared with the control group (p<0.05). At both 3 and 6 years of age, asthmatic children were more frequently mouth breathers than their controls (only statistically significant in the 6-year-olds). In Study III, the mean ± SD DFS was 4.9±5.5 in adolescents with asthma compared with 1.4±2.3 in the control group (p<0.01). The Cariogram data in the control group showed that 75% had a “chance of avoiding caries” compared with 54% in the asthma group (p<0.01). A lower initial and final pH in plaque was found in the asthma groups (only statistically significant in Study III). More gingival inflammation (p<0.05), more frequent mouth breathing (NS) and a lower salivary secretion rate were found in the adolescents and young adults with asthma compared with the control groups (p<0.05). The mean ± SD DFS was 8.6±10.6 in the young adult asthma group compared with 4.0±5.2 in the controls (NS). Conclusions. The results of this thesis indicate that young individuals with asthma have a higher caries prevalence, more gingival inflammation and are more frequently mouth breathers compared with healthy individuals of the same age. In younger children with asthma, a higher intake of sugary drinks was more common and, in the older age group (adolescents and young adults), a lower salivary secretion rate and plaque pH were found in the asthma groups compared with the control groups.
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| 26. |
- Stensson, Malin, et al.
(författare)
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Oral Administration of Lactobacillus reuteri during the First Year of Life Reduces Caries Prevalence in the Primary Dentition at 9 Years of Age
- 2014
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Ingår i: Caries Research. - : S. Karger AG. - 0008-6568 .- 1421-976X. ; 48:2, s. 111-117
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to evaluate the effect on oral health, at age 9 years, of daily oral supplementation with the probiotic Lactobacillus reuteri, strain ATCC 55730, to mothers during the last month of gestation and to children through the first year of life. The study was a single-blind, placebocontrolled, multicenter trial involving 113 children: 60 in the probiotic and 53 in the placebo group. The subjects underwent clinical and radiographic examination of the primary dentition and carious lesions, plaque and gingivitis were recorded. Saliva and plaque were sampled for determination of mutans streptococci (MS) and lactobacilli (LB) in saliva and plaque as well as salivary secretory IgA (SIgA). Forty-nine (82%) children in the probiotic group and 31 (58%) in the placebo group were caries-free (p < 0.01). The prevalence of approximal caries lesions was lower in the probiotic group (0.67 +/- 1.61 vs. 1.53 +/- 2.64; p < 0.05) and there were fewer sites with gingivitis compared to the placebo group (p < 0.05). There were no significant differences between the groups with respect to frequency of toothbrushing, plaque and dietary habits, but to intake of fluoride supplements (p < 0.05). There were no intergroup differences with respect to L. reuteri, MS, LB or SIgA in saliva. Within the limitation of this study it seems that daily supplementation with L. reuteri from birth and during the first year of life is associated with reduced caries prevalence and gingivitis score in the primary dentition at 9 years of age. (c) 2013 S. Karger AG, Basel
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| 27. |
- Stensson, Malin, 1970, et al.
(författare)
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Oral health in pre-school children with asthma--followed from 3 to 6 years.
- 2010
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Ingår i: International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children. - : John Wiley & Sons. - 1365-263X .- 0960-7439. ; 20:3, s. 165-72
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to investigate caries and its determinants in preschool children with and without asthma, followed from 3 to 6 years.
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| 28. |
- Stensson, Malin, 1970, et al.
(författare)
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Oral health in preschool children with asthma
- 2008
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Ingår i: International Journal of Paediatric Dentistry. - 0960-7439 .- 1365-263X. ; 18:4, s. 243-250
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The aim of this study was to investigate oral health and its determinants in 3-year-old and 6-year-old children with asthma. METHODS AND SUBJECTS: Caries and gingivitis were examined in 127 asthmatic (all children with asthma in a selected area and born during a specific time period) and 117 matched, healthy control children.The parents were interviewed regarding various oral-health-related factors. RESULTS: The mean dfs (+/- standard deviation) in the 3-year-old with asthma was 1.4 +/- 3.2 compared with 0.5 +/- 1.2 in the controls (P < 0.05). The corresponding figures for the 6-year-old were 2.5 +/- 3.9 and 1.8 +/- 2.8. The 3-year-old asthmatic children had more gingival bleeding than the healthy controls (P < 0.05). There were no significant differences in gingivitis in the 6-year-old children. Asthmatic children reported higher consumption of sugar-containing drinks and were more frequently mouthbreathers than healthy children (P < 0.05). In 3-year-old children with asthma and immigrant background, the mean dfs was higher compared with immigrant children in the control group (P < 0.01). CONCLUSION: The results indicate that preschool children with asthma have higher caries prevalence than healthy children. The factors discriminating for caries in asthmatic children are higher intake of sugary drinks, mouth breathing, and immigrant background.
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| 29. |
- Stensson, Malin, 1970, et al.
(författare)
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Oral health in young adults with long-term, controlled asthma.
- 2011
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Ingår i: Acta odontologica Scandinavica. - : Informa UK Limited. - 1502-3850 .- 0001-6357. ; 69:3, s. 158-64
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To study oral health in young adults with long-term, controlled asthma. MATERIAL AND METHODS: Twenty 18- to 24-year-olds with a mean duration of asthma of 13.5 [standard deviation (SD) 5.4] years and 20 matched healthy controls were included. A clinical examination was performed and the prevalences of caries, erosions, gingival inflammation, cervicular fluid and periodontal pockets and the plaque formation rate were registered. The salivary flow rate and the numbers of mutans Streptococci and Lactobacilli in saliva were determined. Plaque pH was measured after a sucrose rinse for up to 40 min at two approximal sites. The participants were interviewed regarding dietary and oral hygiene habits. RESULTS: The mean (SD) DFS, including manifest and initial caries, was 8.6 (10.6) in the asthma group and 4.0 (5.2) in the control group (P = 0.09). Initial caries lesions were more common in the asthma group than in the control group: 6.0 (8.1) and 1.3 (2.0), respectively (P = 0.02). The asthma group had more gingivitis (P = 0.01) and a lower stimulated salivary secretion rate than the controls (P = 0.01). The asthmatics also had a somewhat, although not statistically significant, lower initial pH value in plaque and a more pronounced pH drop compared with the controls. In the asthma group, 65% reported frequent mouthbreathing, compared with 10% of the controls (P = 0.01). No differences were found in tooth-brushing or dietary habits between the groups. CONCLUSION: Young adults with long-term, controlled asthma had more initial caries, more gingival inflammation and a lower stimulated salivary secretion rate than individuals without asthma.
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| 30. |
- Stensson, Malin, 1970-, et al.
(författare)
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Parents' perceptions of oral health, general health and dental health care for children with Down syndrome in Sweden
- 2021
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Ingår i: Acta Odontologica Scandinavica. - : Taylor & Francis. - 0001-6357 .- 1502-3850. ; 79:4, s. 248-255
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To describe parental perceptions of general health, oral health and received dental health care in Swedish children with Down syndrome (DS).METHODS: Online questionnaire, quantitative data analysis (Chi-square test).RESULTS: Parents of 101 children with DS (52 boys, 49 girls, mean age: 9.6 years) participated. Seventy percent rated their child's general health and 74% their child's oral health as good or very good. Parents, who rated their child's oral health as poor (8%), also reported that dental procedures were difficult. Children received dental care at general (55%) and specialist clinics (53%). Ninety-four percent of parents of children receiving specialist dental health care were satisfied compared to 70% of parents with children in general clinics. The parents most valued characteristics of dental professionals were patience (63%) and their ability to engage the child (68%). Parents wanted multidisciplinary collaboration.CONCLUSION: Most parents rated their child's general and oral health as good or very good. Children with poor oral health were also reported to have difficulties coping with dental procedures. Parents wanted dental care to be tailored to meet their child's unique needs. They wanted dental professionals to have knowledge about children with a need for special care. Lastly, they requested multidisciplinary collaboration.
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| 31. |
- Stensson, Malin
(författare)
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Unga astmatiker behöver förebyggande vårdprogram
- 2011
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Ingår i: Tandläkartidningen. - 0039-6982. ; :9, s. 60-63
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Majoriteten av de studier som undersökt den orala hälsan hos personer med astma visar att astmatiker löper en ökad risk för orala sjukdomar, särskilt karies. Denna studie understryker vikten av att utveckla förebyggande vårdprogram för unga personer med astma.
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| 32. |
- Stensson, Niclas, et al.
(författare)
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Increased Anandamide and Decreased Pain and Depression after Exercise in Fibromyalgia
- 2020
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Ingår i: Medicine & Science in Sports & Exercise. - : LIPPINCOTT WILLIAMS & WILKINS. - 0195-9131 .- 1530-0315. ; 52:7, s. 1617-1628
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Tidskriftsartikel (refereegranskat)abstract
- Purpose Physical exercise is increasingly being promoted by health care for chronic pain conditions with beneficial outcomes, such as pain and fatigue reduction, and increased quality of life. Nevertheless, knowledge about biochemical consequences of physical exercise in chronic pain is still relatively poor. The endocannabinoid system has been suggested to play a role for acute exercise-induced reward and pain inhibition. The aim of this study is to investigate the chronic outcomes of resistance exercise on levels of endocannabinoids and related lipids in fibromyalgia (FM). Methods This study examine the outcomes of a 15-wk person-centered resistance exercise program on plasma levels of the lipid mediators; anandamide, 2-arachidonoylglycerol (2-AG), oleoylethanolamide, palmitoylethanolamide, and stearoylethanolamide (SEA) sampled from 37 women with FM and 33 healthy controls. The associations between clinical scorings of pain, depression, anxiety, fatigue, and muscle strength with levels of these lipid mediators before and after the exercise program are also analyzed. Results After the 15-wk exercise program, anandamide levels were significantly increased, and SEA levels significantly decreased in FM. Pain intensity and depression scorings decreased and muscle strength increased, and in a multivariate context, muscle strength was positively associated with 2-AG levels after the resistance exercise program in FM. Conclusions The increased anandamide and decreased SEA in women with FM after the 15-wk program might point to a chronic effect of resistance exercise. Pain and depression scorings decreased in the FM group after the program, but no associations between pain, depression, and lipid level changes were assured.
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