1. |
- Kanai, M, et al.
(författare)
-
- 2023
-
swepub:Mat__t
|
|
2. |
- Niemi, MEK, et al.
(författare)
-
- 2021
-
swepub:Mat__t
|
|
3. |
|
|
4. |
- Kueppers, Michael, et al.
(författare)
-
Triple F-a comet nucleus sample return mission
- 2009
-
Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 23:3, s. 809-847
-
Tidskriftsartikel (refereegranskat)abstract
- The Triple F (Fresh From the Fridge) mission, a Comet Nucleus Sample Return, has been proposed to ESA's Cosmic Vision program. A sample return from a comet enables us to reach the ultimate goal of cometary research. Since comets are the least processed bodies in the solar system, the proposal goes far beyond cometary science topics (like the explanation of cometary activity) and delivers invaluable information about the formation of the solar system and the interstellar molecular cloud from which it formed. The proposed mission would extract three sample cores of the upper 50 cm from three locations on a cometary nucleus and return them cooled to Earth for analysis in the laboratory. The simple mission concept with a touch-and-go sampling by a single spacecraft was proposed as an M-class mission in collaboration with the Russian space agency ROSCOSMOS.
|
|
5. |
- Kaminski, T., et al.
(författare)
-
The BETHY/JSBACH Carbon Cycle Data Assimilation System: experiences and challenges
- 2013
-
Ingår i: Journal of Geophysical Research - Biogeosciences. - : American Geophysical Union (AGU). - 2169-8953. ; 118:4, s. 1414-1426
-
Forskningsöversikt (refereegranskat)abstract
- We present the concept of the Carbon Cycle Data Assimilation System and describe its evolution over the last two decades from an assimilation system around a simple diagnostic model of the terrestrial biosphere to a system for the calibration and initialization of the land component of a comprehensive Earth system model. We critically review the capability of this modeling framework to integrate multiple data streams, to assess their mutual consistency and with the model, to reduce uncertainties in the simulation of the terrestrial carbon cycle, to provide, in a traceable manner, reanalysis products with documented uncertainty, and to assist the design of the observational network. We highlight some of the challenges we met and experience we gained, give recommendations for operating the system, and suggest directions for future development.
|
|
6. |
- Stroud, J.T., et al.
(författare)
-
Priority effects transcend scales and disciplines in biology
- 2024
-
Ingår i: Trends in Ecology & Evolution. - : Elsevier. - 0169-5347 .- 1872-8383.
-
Forskningsöversikt (refereegranskat)abstract
- Although primarily studied through the lens of community ecology, phenomena consistent with priority effects appear to be widespread across many different scenarios spanning a broad range of spatial, temporal, and biological scales. However, communication between these research fields is inconsistent and has resulted in a fragmented co-citation landscape, likely due to the diversity of terms used to refer to priority effects across these fields. We review these related terms, and the biological contexts in which they are used, to facilitate greater cross-disciplinary cohesion in research on priority effects. In breaking down these semantic barriers, we aim to provide a framework to better understand the conditions and mechanisms of priority effects, and their consequences across spatial and temporal scales.
|
|
7. |
- Anderson, N. John, et al.
(författare)
-
The Arctic in the Twenty-First Century : Changing Biogeochemical Linkages across a Paraglacial Landscape of Greenland
- 2017
-
Ingår i: BioScience. - : Oxford University Press. - 0006-3568 .- 1525-3244. ; 67:2, s. 118-133
-
Tidskriftsartikel (refereegranskat)abstract
- The Kangerlussuaq area of southwest Greenland encompasses diverse ecological, geomorphic, and climate gradients that function over a range of spatial and temporal scales. Ecosystems range from the microbial communities on the ice sheet and moisture-stressed terrestrial vegetation (and their associated herbivores) to freshwater and oligosaline lakes. These ecosystems are linked by a dynamic glacio-fluvial-aeolian geomorphic system that transports water, geological material, organic carbon and nutrients from the glacier surface to adjacent terrestrial and aquatic systems. This paraglacial system is now subject to substantial change because of rapid regional warming since 2000. Here, we describe changes in the eco-and geomorphic systems at a range of timescales and explore rapid future change in the links that integrate these systems. We highlight the importance of cross-system subsidies at the landscape scale and, importantly, how these might change in the near future as the Arctic is expected to continue to warm.
|
|
8. |
- Van Haute, L., et al.
(författare)
-
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease
- 2023
-
Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 14:1
-
Tidskriftsartikel (refereegranskat)abstract
- Mutations in the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by impaired mitochondrial respiration. Within this group, an increasing number of mutations have been identified in nuclear genes involved in mitochondrial RNA biology. The TEFM gene encodes the mitochondrial transcription elongation factor responsible for enhancing the processivity of mitochondrial RNA polymerase, POLRMT. We report for the first time that TEFM variants are associated with mitochondrial respiratory chain deficiency and a wide range of clinical presentations including mitochondrial myopathy with a treatable neuromuscular transmission defect. Mechanistically, we show muscle and primary fibroblasts from the affected individuals have reduced levels of promoter distal mitochondrial RNA transcripts. Finally, tefm knockdown in zebrafish embryos resulted in neuromuscular junction abnormalities and abnormal mitochondrial function, strengthening the genotype-phenotype correlation. Our study highlights that TEFM regulates mitochondrial transcription elongation and its defect results in variable, tissue-specific neurological and neuromuscular symptoms.
|
|
9. |
|
|
10. |
- Hedin, Jonas, et al.
(författare)
-
The MAGIC meteoric smoke particle sampler
- 2014
-
Ingår i: Journal of Atmospheric and Solar-Terrestrial Physics. - : Elsevier BV. - 1364-6826 .- 1879-1824. ; 118, s. 127-144
-
Tidskriftsartikel (refereegranskat)abstract
- Between a few tons to several hundred tons of meteoric material enters the Earth's atmosphere each day, and most of this material is ablated and vaporized in the 70-120 km altitude region. The subsequent chemical conversion, re-condensation and coagulation of this evaporated material are thought to form nanometre sized meteoric smoke particles (MSPs). These smoke particles are then subject to further coagulation, sedimentation and global transport by the mesospheric circulation. MSPs have been proposed as a key player in the formation and evolution of ice particle layers around the mesopause region, i.e. noctilucent clouds (NLC) and polar mesosphere summer echoes (PMSE). MSPs have also been implicated in mesospheric heterogeneous chemistry to influence the mesospheric odd oxygen/odd hydrogen (O-x/HOx) chemistry, to play an important role in the mesospheric charge balance, and to be a significant component of stratospheric aerosol and enhance the depletion of O-3. Despite their apparent importance, little is known about the properties of MSPs and none of the hypotheses can be verified without direct evidence of the existence, altitude and size distribution, shape and elemental composition. The aim of the MAGIC project (Mesospheric Aerosol - Genesis, Interaction and Composition) was to develop an instrument and analysis techniques to sample for the first time MSPs in the mesosphere and return them to the ground for detailed analysis in the laboratory. MAGIC meteoric smoke particle samplers have been flown on several sounding rocket payloads between 2005 and 2011. Several of these flights concerned non-summer mesosphere conditions when pure MSP populations can be expected. Other flights concerned high latitude summer conditions when MSPs are expected to be contained in ice particles in the upper mesosphere. In this paper we present the MAGIC project and describe the MAGIC MSP sampler, the measurement procedure and laboratory analysis. We also present the attempts to retrieve MSPs from these flights, the challenges inherent to the sampling of nanometre sized particles and the subsequent analysis of the sampled material, and thoughts for the future. Despite substantial experimental efforts, the MAGIC project has so far failed to provide conclusive results. While particles with elemental composition similar to what is to be expected from MSPs have been found, the analysis has been compromised by challenges with different types of contamination and uncertainties in the sticking efficiency of the particles on the sampling surfaces.
|
|
11. |
|
|
12. |
- Wayne, Greg, et al.
(författare)
-
Principles of Systems Biology, No. 11
- 2016
-
Ingår i: CELL SYSTEMS. - : CELL PRESS. - 2405-4712. ; 3:5, s. 406-410
-
Tidskriftsartikel (refereegranskat)abstract
- This month: AI that learns patterns and facts, new protein-RNA and protein-protein relationships, engineering signaling and metabolism, and more variants of Cas9.
|
|
13. |
- Yabuta, Hikaru, et al.
(författare)
-
Macromolecular organic matter in samples of the asteroid (162173) Ryugu
- 2023
-
Ingår i: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 379:6634
-
Tidskriftsartikel (refereegranskat)abstract
- Samples of the carbonaceous asteroid (162173) Ryugu were collected and brought to Earth by the Hayabusa2 spacecraft. We investigated the macromolecular organic matter in Ryugu samples and found that it contains aromatic and aliphatic carbon, ketone, and carboxyl functional groups. The spectroscopic features of the organic matter are consistent with those in chemically primitive carbonaceous chondrite meteorites that experienced parent-body aqueous alteration (reactions with liquid water). The morphology of the organic carbon includes nanoglobules and diffuse carbon associated with phyllosilicate and carbonate minerals. Deuterium and/or nitrogen-15 enrichments indicate that the organic matter formed in a cold molecular cloud or the presolar nebula. The diversity of the organic matter indicates variable levels of aqueous alteration on Ryugus parent body.
|
|