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| 2. |
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| 3. |
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| 4. |
- Bauer, M., et al.
(författare)
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Solar insolation in springtime influences age of onset of bipolar I disorder
- 2017
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 136:6, s. 571-582
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Forskningsöversikt (refereegranskat)abstract
- Objective: To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. Method: Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth-cohort, family history, polarity of first episode and country physician density. Results: There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset. This effect was reduced in those without a family history of mood disorders and with a first episode of mania rather than depression. The maximum monthly increase occurred in springtime. The youngest birth-cohort had the youngest age of onset. All prior relationships were confirmed using both the entire sample, and only the youngest birth-cohort (all estimated coefficients P < 0.001). Conclusion: A large increase in springtime solar insolation may impact the onset of bipolar disorder, especially with a family history of mood disorders. Recent societal changes that affect light exposure (LED lighting, mobile devices backlit with LEDs) may influence adaptability to a springtime circadian challenge.
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| 5. |
- Bauer, M., et al.
(författare)
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Association between polarity of first episode and solar insolation in bipolar I disorder
- 2022
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Ingår i: Journal of Psychosomatic Research. - : Elsevier BV. - 0022-3999 .- 1879-1360. ; 160
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar insolation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P ≤ 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.
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| 6. |
- Bauer, M., et al.
(författare)
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Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
- 2023
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Ingår i: International Journal of Bipolar Disorders. - 2194-7511. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundSunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample.MethodsData for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P <= 0.001.ResultsThe 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger.ConclusionUVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
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| 7. |
- Bauer, M., et al.
(författare)
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Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
- 2021
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Ingår i: International Journal of Bipolar Disorders. - : Springer Science and Business Media LLC. - 2194-7511. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- Background Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. Methods Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun's electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). Results This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. Conclusion A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed.
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| 8. |
- Bowman, L. R., et al.
(författare)
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Alarm Variables for Dengue Outbreaks: A Multi-Centre Study in Asia and Latin America
- 2016
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Ingår i: Plos One. - : Public Library of Science (PLoS). - 1932-6203. ; 11:6
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Tidskriftsartikel (refereegranskat)abstract
- Background Worldwide, dengue is an unrelenting economic and health burden. Dengue outbreaks have become increasingly common, which place great strain on health infrastructure and services. Early warning models could allow health systems and vector control programmes to respond more cost-effectively and efficiently. The Shewhart method and Endemic Channel were used to identify alarm variables that may predict dengue outbreaks. Five country datasets were compiled by epidemiological week over the years 2007-2013. These data were split between the years 2007-2011 (historic period) and 2012-2013 (evaluation period). Associations between alarm/outbreak variables were analysed using logistic regression during the historic period while alarm and outbreak signals were captured during the evaluation period. These signals were combined to form alarm/outbreak periods, where 2 signals were equal to 1 period. Alarm periods were quantified and used to predict subsequent outbreak periods. Across Mexico and Dominican Republic, an increase in probable cases predicted outbreaks of hospitalised cases with sensitivities and positive predictive values (PPV) of 93%/83% and 97%/86% respectively, at a lag of 1-12 weeks. An increase in mean temperature ably predicted outbreaks of hospitalised cases in Mexico and Brazil, with sensitivities and PPVs of 79%/73% and 81%/46% respectively, also at a lag of 1-12 weeks. Mean age was predictive of hospitalised cases at sensitivities and PPVs of 72%/74% and 96%/45% in Mexico and Malaysia respectively, at a lag of 4-16 weeks. An increase in probable cases was predictive of outbreaks, while meteorological variables, particularly mean temperature, demonstrated predictive potential in some countries, but not all. While it is difficult to define uniform variables applicable in every country context, the use of probable cases and meteorological variables in tailored early warning systems could be used to highlight the occurrence of dengue outbreaks or indicate increased risk of dengue transmission.
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| 9. |
- Bauer, Michael, et al.
(författare)
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Association between solar insolation and a history of suicide attempts in bipolar I disorder.
- 2019
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Ingår i: Journal of psychiatric research. - : Elsevier BV. - 1879-1379 .- 0022-3956. ; 113, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- In many international studies, rates of completed suicide and suicide attempts have a seasonal pattern that peaks in spring or summer. This exploratory study investigated the association between solar insolation and a history of suicide attempt in patients with bipolar I disorder. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area on Earth. Data were collected previously from 5536 patients with bipolar I disorder at 50 collection sites in 32 countries at a wide range of latitudes in both hemispheres. Suicide related data were available for 3365 patients from 310 onset locations in 51 countries. 1047 (31.1%) had a history of suicide attempt. There was a significant inverse association between a history of suicide attempt and the ratio of mean winter solar insolation/mean summer solar insolation. This ratio is smallest near the poles where the winter insolation is very small compared to the summer insolation. This ratio is largest near the equator where there is relatively little variation in the insolation over the year. Other variables in the model that were positively associated with suicide attempt were being female, a history of alcohol or substance abuse, and being in a younger birth cohort. Living in a country with a state-sponsored religion decreased the association. (All estimated coefficients p<0.01). In summary, living in locations with large changes in solar insolation between winter and summer may be associated with increased suicide attempts in patients with bipolar disorder. Further investigation of the impacts of solar insolation on the course of bipolar disorder is needed.
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| 10. |
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| 11. |
- Sartelli, Massimo, et al.
(författare)
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Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action
- 2023
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Ingår i: WORLD JOURNAL OF EMERGENCY SURGERY. - 1749-7922. ; 18:1
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Forskningsöversikt (refereegranskat)abstract
- Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice.
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| 12. |
- Damayanti, A., et al.
(författare)
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Respirometric analysis of activated sludge models from palm oil mill effluent
- 2010
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Ingår i: Bioresource Technology. - : Elsevier BV. - 1873-2976 .- 0960-8524. ; 101:1, s. 144-149
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Tidskriftsartikel (refereegranskat)abstract
- Activated sludge models (ASMs) have been widely used as a basis for further model development in wastewater treatment processes. Values for parameters to be used are vital for the accuracy of the modeling approach. A continuous stirred tank reactor (CSTR), as open respirometer with continuous flow for 20 h is used in ASMs. The dissolved oxygen (DO) profile for 11 days was monitored. It was found the mass transfer coefficient K-La is 0.3 h(-1) during lag and start feed phase and 0.01 h(-1) during stop feed phase, while the heterotrophic yield coefficient Y-H is 0.44. Some of the chemical oxygen demand (COD) fractionations of palm oil mill effluent (POME) using respirometric test in ASM models are S-s 50 mg/L, S-1 16,600 mg/L, X-S 25,550 mg/L, and X-1 2,800 mg/L The comparison of experimental and ASM I from OUR concentration is found to fit well. (C) 2009 Elsevier Ltd. All rights reserved.
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| 13. |
- Farrell, W. M., et al.
(författare)
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Saturn's Plasma Density Depletions Along Magnetic Field Lines Connected to the Main Rings
- 2018
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Ingår i: Geophysical Research Letters. - : AMER GEOPHYSICAL UNION. - 0094-8276 .- 1944-8007. ; 45:16, s. 8104-8110
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Tidskriftsartikel (refereegranskat)abstract
- We report on a set of clear and abrupt decreases in the high-frequency boundary of whistler mode emissions detected by Cassini at high latitudes (about +/- 40 degrees) during the low-altitude proximal flybys of Saturn. These abrupt decreases or dropouts have start and stop locations that correspond to L shells at the edges of the A and B rings. Langmuir probe measurements can confirm, in some cases, that the abrupt decrease in the high-frequency whistler mode boundary is associated with a corresponding abrupt electron density dropout over evacuated field lines connected to the A and B rings. Wideband data also reveal electron plasma oscillations and whistler mode cutoffs consistent with a low-density plasma in the region. The observation of the electron density dropout along ring-connecting field lines suggests that strong ambipolar forces are operating, drawing cold ionospheric ions outward to fill the flux tubes. There is an analog with the refilling of flux tubes in the terrestrial plasmasphere. We suggest that the ring-connected electron density dropouts observed between 1.1 and 1.3 R-s are connected to the low-density ring plasma cavity observed overtop the A and B rings during the 2004 Saturn orbital insertion pass.Plain Language Summary We present Cassini observations during the close passes by the planet Saturn indicating that plasma on magnetic field lines that pass through the A and B rings is of anomalously low density. These observations are consistent with the Saturn orbit insertion observations of a plasma cavity located at equatorial regions overtop the dense B ring. Using a terrestrial analogy, we suggest that the low-density conditions overtop the rings create an electrical force, called an ambipolar electric field that draws plasma out of the ionosphere in an attempt to replenish the plasma void found at equatorial regions.
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| 14. |
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| 15. |
- Holmer, Hampus, et al.
(författare)
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The rate and perioperative mortality of caesarean section in Sierra Leone
- 2019
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Ingår i: BMJ Global Health. - : BMJ. - 2059-7908. ; 4:5
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Tidskriftsartikel (refereegranskat)abstract
- Introduction Sierra Leone has the world's highest maternal mortality, partly due to low access to caesarean section. Limited data are available to guide improvement. In this study, we aimed to analyse the rate and mortality of caesarean sections in the country. Methods We conducted a retrospective study of all caesarean sections and all reported in-facility maternal deaths in Sierra Leone in 2016. All facilities performing caesarean sections were visited. Data on in-facility maternal deaths were retrieved from the Maternal Death Surveillance and Response database. Caesarean section mortality was defined as in-facility perioperative mortality. Results In 2016, there were 7357 caesarean sections in Sierra Leone. This yields a population rate of 2.9% of all live births, a 35% increase from 2012, with district rates ranging from 0.4% to 5.2%. The most common indications for surgery were obstructed labour (42%), hypertensive disorders (25%) and haemorrhage (22%). Ninety-nine deaths occurred during or after caesarean section, and the in-facility perioperative caesarean section mortality rate was 1.5% (median 0.7%, IQR 0-2.2). Haemorrhage was the leading cause of death (73%), and of those who died during or after surgery, 80% had general anaesthesia, 75% received blood transfusion and 22% had a uterine rupture diagnosed. Conclusions The caesarean section rate has increased rapidly in Sierra Leone, but the distribution remains uneven. Caesarean section mortality is high, but there is wide variation. More access to caesarean sections for maternal and neonatal complications is needed in underserved areas, and expansion should be coupled with efforts to limit late presentation, to offer assisted vaginal delivery when indicated and to ensure optimal perioperative care.
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| 16. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Business Process Modeling for Domain Inbound Logistics System : Analytical Perspective with BPMN 2.0
- 2013
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Ingår i: Journal of Basic and Applied Scientific Research. - : Textroad. - 2090-4304. ; 3:9, s. 569-578
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Tidskriftsartikel (refereegranskat)abstract
- Among different Business Process Management strategies and methodologies, one common feature is to captureexisting processes and representing the new processes adequately. Business Process Modelling (BPM) plays acrucial role on such an effort. This paper proposes a “to-be” inbound logistics business processes model usingBPMN 2.0 standard specifying the structure and behaviour of the system within the SME environment. Thegeneric framework of inbound logistics model consists of one main high-level module-based system namedOrder System comprising of four main sub-systems of the Order core, Procure, Auction, and Purchase systems.The system modelingis elaborately discussed to provide a business analytical perspective from various activitiesin inbound logistics system. Since the main purpose of the paper is to map out the functionality and behaviour ofLogistics system requirements, employing the model is of a great necessity on the future applications at systemdevelopment such as in the data modelling effort. Moreover, employing BPMN 2.0 method and providingexplanatory techniques as a nifty guideline and framework to assist the business process practitioners, analystsand managers at identical systems.
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| 17. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Business Process Modeling for Domain Outbound Logistics System: Analytic Perspective with BPMN 2.0
- 2013
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Ingår i: World Applied Sciences Journal. - : IDOSI publications. - 1818-4952 .- 1991-6426. ; 28:3, s. 367-377
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Tidskriftsartikel (refereegranskat)abstract
- This paper proposes a generic"to-be" business processes model for domain highest-level outbound logistics system representing the possible alternative structure and behaviour of the system in respect to x-party logistics services applicable in Small-to-medium sized enterprises. The generic framework of outbound logistics model consists of one main modular system named as the Shipping System including five internal sub-systems of the shipping core, shipping requirement, First Party Logistics (1PL), Third Party Logistics (3PL) and Customer Relationship Management (CRM) systems. The shipping system business process model supports all outbound logistics activities interacting with the customer, 3PL provider and other back office systems such as order system and inventory system. The modelling procedure is elaborately discussed to provide a business analytical view from various activities within the outbound logistics system. Moreover, the model provides essential knowledge input for system development and improvement through capturing all significant highest-level business process and sub-processes and revealing potential automation capabilities on data capturingas well as the process monitoring.
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| 18. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Business Process Modeling in Production Logistics : Complementary Use of BPMN and UML
- 2013
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Ingår i: Middle East Journal of Scientific Research. - : International Digital Organization for Scientific Information. - 1990-9233. ; 15:4, s. 516-529
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Tidskriftsartikel (refereegranskat)abstract
- This paper investigates the suitability and sufficincy of BPMN language in business processmodelling. Production logistics system is modeled at the highest domain level using case study in carcomponent industry to examine the language in every aspect. Modelling is carried out in a modular basis forthree main sub-systems generally using BPMN 2.0. Complementary use of other modeling tool to cover all thecritical flows of objects and associate data in modeling was seen necessary and addressed using UML activitydiagrams employing the specific capability of modeling the material flow and semantics. Modeling the flow ofobjects provides the comprehensive perspective of the whole system and fulfill the need of capturing allundepicted object flows as well as processes and data which may not be sheerly covered using the BPMN. Theproposed models provides great beneficial referentiality for modelers, analyists and actual practitioners oflogistics activities. The significant explanatory description and strategy are the key feature of the paper tofollow using state-of-the- art modeling tool of BPMN 2.0 and UML.
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| 19. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Extending Quality Data for Lot-based Traceability System in SME
- 2010
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Ingår i: Proceedings 2010 International Symposium on Information Technology - System Development and Application and Knowledge Society, ITSim'10. - : IEEE Computer Society Digital Library. - 9781424467181 ; , s. 1158-1163
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Konferensbidrag (refereegranskat)abstract
- This paper addressed extending quality data in lot-based traceability information system through modeling and evaluation which is purposely designed for small-to-medium size enterprise (SMEs). The solution translates the system behavior and value data arisen from traceability requirement into useful and organized computerized information system. Easy- understanding and economic approach in design and implementation meets conditions of SME environment. The designed information system through data query evaluates the functionality of quality data dynamically.
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| 20. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Inbound Logistics Data Transaction System Modeling in SME : Transition from BPM to Data Modeling
- 2013
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Ingår i: World Applied Sciences Journal. - : IDOSI Publications. - 1818-4952 .- 1991-6426. ; 24:6, s. 772-783
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Tidskriftsartikel (refereegranskat)abstract
- This study focuses on capturing all process-based data transaction system for the highest level ofabstraction in inbound logistics activities in SME environment. As a business process modelling toolobjective to provide better understanding and analytical view of the system, Data Flow Diagrams (DFD) arechosen due to the specific features of depicting the information movement and a complete set of diagrams aregenerated including the Context, Level 0 and Level 1 diagrams. The proposed DFDs for inbound logisticssystem provide transitional views for the system which is not easily achievable merely through businessprocess modelling (BPM) at identification of data dependencies, system components and data bundlespecification details required for an object-oriented and module-based conceptual and logical data modellingeffort. As the results, all system components as well as all data repositories and data bundles to be used indatabase blueprint design and messaging and notification system development are identified.
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| 21. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Inventory System and Functionality Evaluation for Production Logistics
- 2013
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Ingår i: Journal of Theoretical and Applied Information Technology. - : JATIT & LLS. - 1992-8645 .- 1817-3195. ; 54:3, s. 377-387
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Tidskriftsartikel (refereegranskat)abstract
- This paper addressed a comprehensive modelling and functionality requirement evaluation of perpetual production logistics inventory system for small-to-medium enterprises. The main idea is to analyse the system behaviour and data transactions invoked by a module-based inventory system using business process modelling and object-oriented data modelling techniques. The paper explains through the methodology and modelling procedure which eventually leads to a computerized inventory information system as a module able to be integrated with other back office systems in production logistics. The system is able to manipulate all inbound warehousing operations including docking, storing, and retrieval data as well as actual inventory SKU balance dynamically to keep the inventory data instantly up-to-date and in real-time. The functionality of the solution is evaluated based on the identified inventory system requirements responding to all inventory controlling of receiving, allocating, load balancing, and traceability linking through different types of lookups and data queries.
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| 22. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Module-based QIS Modeling for Production Logistics in SME
- 2014
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Ingår i: Research Journal of Applied Sciences, Engineering and Technology. - : Maxwell Scientific Organization. - 2040-7459 .- 2040-7467. ; 7:1, s. 183-190
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Tidskriftsartikel (refereegranskat)abstract
- This study proposes an object-oriented modelling for the quality information system as a module able to be integrated with other production logistics back office systems. Using the UML modelling tools such as component and class diagrams, the model addresses the highest level quality business processes and data structure as well as all identified providing and depending interfaces and the messaging system in a module-based framework design. The methodology and adopted procedures are explained in details of which provide a better understanding of the modelling and the possibility for the lower-levels quality data extensions following the same framework. The model is able to manipulate all quality control data for purchasing, production and remedy operation in a lot-based make-to-order production system within a defined module.
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| 23. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Object-oriented Design Framework for Stock Keeping Unit Generating System
- 2013
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Ingår i: Jurnal Teknologi. - : Penerbit UTM Press. - 2180-3722 .- 0127-9696. ; 63:1, s. 81-86
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Tidskriftsartikel (refereegranskat)abstract
- This paper proposes an object-oriented design for generating Stock Keeping Unit coding system. Through recognition and analysis of the inventory item particulars and conceptualizing the important classes as one package, the framework is developed in a modular-basis able to be integrated with other parts of the system. Using UML class and package diagram as of the best practice in object-oriented, conducting the analysis and design is elaborately discussed. A prototype implementation is carried out to support the designed framework over its applicability at a modular information system. Moreover, the item particular package with unique and organized SKU numbering system efficiently supports the fundamental need of item identification at inventory control operations and classification and guarantees different types of reports and lookups.
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| 24. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Object-oriented Modelling for Module-based Production Logistics Inventory System
- 2013
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Ingår i: Australian Journal of Basic and Applied Sciences. - 1991-8178 .- 2309-8414. ; 7:7, s. 555-562
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Tidskriftsartikel (refereegranskat)abstract
- This paper proposes module-based object-oriented data models for inventory systemfocusing on the production logistics business processes. It expounds the methodology and modellingprocedure to provide the inventory system requirements. Through warehousing business processanalysis for production logistics and based on the object-oriented technique in a modular basis, thedomain and entity class diagrams are modelled. Through identifying all the required and realizingsystem interfaces, the system is able to be integrated with other back office systems. The model is ableto manipulate all warehousing operation data including receiving, storing, retrieval, allocations andtraceability, and load balancing for actual inventory stock keeping units in real-time to support quickdecision making with minimum efforts and or errors.
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| 25. |
- Khabbazi, Mahmood Reza, 1972-, et al.
(författare)
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Process-based material workflow modeling in inbound logistics : modeling tools evaluation
- 2014
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Ingår i: Middle East Journal of Scientific Research. - : IDOSI Pubilcations. - 1990-9233 .- 1999-8147. ; 20:12, s. 1699-1708
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Tidskriftsartikel (refereegranskat)abstract
- This paper evaluates the suitability of the workflow modeling tools through process-based materialworkflow perspective. A case example in inbound logistics system of “Resource Reception” workflow at thehighest domain abstract level is examined with four nominated workflow modeling standards of Data FlowDiagram (DFD), Event-based Process Control (EPC), Business Process Model and Notation (BPMN) andUnified Modeling Language (UML) Activity Diagrams (AD). Focusing on the physical object diagramingsyntax and semantics, the essential factors of the flows, consumption pattern and states for physical objectsas well as readability, easiness and comprehensiveness of the modeling tools were discussed throughout themodeling development. The models and comparative evaluation results clearly demonstrates the superiorityand advantages of using UML Ads at the workflow modeling providing an extensive view of the whole systemfunctionalities and behavior fulfilling the necessity of capturing any undepicted entity that might hold the keyof improvement in Business Process Management (BPM).
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| 26. |
- Magliyah, Moustafa S., et al.
(författare)
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Evolution of macular hole in enhanced S-cone syndrome
- 2021
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Ingår i: Documenta Ophthalmologica. - : Springer Science and Business Media LLC. - 0012-4486 .- 1573-2622. ; 142:2, s. 239-245
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To describe the stages of development and natural course of a full-thickness macular hole (FTMH) in a patient with enhanced S-cone syndrome (ESCS). Methods: This study reported the serial ophthalmologic examinations and macular spectral-domain optical coherence tomography (SD-OCT) imaging over a period of 6 years in a 29-year-old man with ESCS confirmed by electroretinography (ERG) and NR2E3 molecular genetic analysis. Results: At presentation, patient had night blindness and visual acuity (VA) of 20/300 in the right eye (OD) and 20/100 in the left eye (OS). Examination showed bilateral retinal midperipheral pigmentary deposits and a macular schisis in OD. Electroretinography and NR2E3 genetic analysis confirmed ESCS. A year later, a lamellar MH (LMH) appeared at the fovea in OD. SD-OCT confirmed it as inner retinal layer LMH with outer retinal preservation and displayed, on the temporal side of the LMH, prominent splitting between the inner and outer retinal layers. At 2 years, a focal defect in the ellipsoid zone appeared on SD-OCT, followed by split in the outer retinal layer creating a progressively expanding outer LMH. The latter had rolled edges which then fused with the inner LMH margins creating a single full-thickness FTMH. Over the next 4 years, enlargement of the FTMH with increased adjacent retinal splitting continued. No visible vitreous abnormalities or vitreoretinal traction forces were identified at any stage during follow-up. VA OD remained unchanged. Conclusion: This case illustrates that the clinical evolution of FTMH in ESCS may be progressive and likely involves degeneration and intraretinal, rather than vitreoretinal, traction. This should be kept in mind when considering surgical intervention in these cases.
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| 27. |
- Magliyah, Moustafa S., et al.
(författare)
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Leprel1-related Giant Retinal Tear Detachments Mimic the Phenotype of Ocular Stickler Syndrome
- 2023
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Ingår i: Retina. - 0275-004X. ; 43:3, s. 498-505
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Tidskriftsartikel (refereegranskat)abstract
- Purpose:To describe the features of retinal detachments and high myopia in patients with novel pathogenic variants in LEPREL1 and report a possible association with nephropathy.Methods:Retrospective study of 10 children with biallelic LEPREL1 pathogenic variants. Data included ophthalmic features, surgical interventions, and genetic and laboratory findings.Results:10 patients (8 females) from three families with homozygous (2) or compound heterozygous (1) variants in LEPREL1 were included. At presentation, mean age was 9.9 ± 2.6 years. Mean axial length was 28.9 ± 1.9 mm and mean refraction was -13.9 ± 2.8 diopters. Bilateral posterior subcapsular cataracts were present in eight patients (80%), with lens subluxation in five eyes of three patients (30%). Rhegmatogenous retinal detachments (RRD), associated with giant retinal tears (GRT), developed in seven eyes of five patients (50%) at a mean age of 14.14 ± 5.9 years. Six were successfully reattached with mean Snellen best-corrected visual acuity improving from 20/120 preoperatively to 20/60 at last follow-up. Urinalysis in nine patients revealed microhematuria and/or mild proteinuria in six patients (67%).Conclusion:LEPREL1-related high myopia confers a high risk of early-onset GRT-related RRD. The ocular phenotype may be confused with that of ocular Stickler syndrome if genetic testing is not performed. Further investigations into a potential association with renal dysfunction are warranted.
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| 28. |
- Magliyah, Moustafa S., et al.
(författare)
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Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1
- 2020
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Ingår i: Ophthalmology Retina. - : Elsevier BV. - 2468-6530. ; 4:1, s. 77-83
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Konferensbidrag (refereegranskat)abstract
- Purpose: To describe a new form of childhood-onset rhegmatogenous retinal detachment (RRD) in autosomal recessive high myopia associated with mutations in LRPAP1. Design: Retrospective cohort study. Participants: A total of 12 children (24 eyes) with recessive LRPAP1 mutations and associated high myopia. Methods: Serial ophthalmological examination and retinal imaging during 4.6±1.9 (mean ± standard deviation) years. Retinal interventions included prophylactic laser and surgical retinal repair. Main Outcome Measures: Incidence and recurrence rate of RRD and retinal break formation. Association between LRPAP1 genotypes and RRD characteristics. Results: Some 42% of children (5 children [6 eyes]) developed RRD at the age of 10.43±0.97 years. Four of the children who developed RRD were male (80%), and 1 was female (20%). Visual acuity was significantly reduced in eyes with RRD at presentation and at the most recent visit compared with eyes with no RRD (P < 0.001 for both). Two eyes had inoperable RRD. Four eyes for which primary retinal repair was done had redetachment (100% of operated eyes) due to variable degrees of proliferative vitreoretinopathy (PVR). Reattachment after surgical repair, which was maintained at least during 6 months of follow-up, was achieved in 3 eyes (75%), with final visual acuities of 20/300 in 2 eyes and 20/400 in 1 eye. Conclusions: This is the first description of a nonsyndromic, high myopia-related, recessive RRD without any signs of vitreoretinal degeneration. Recessive LRPAP1 gene mutations confer a high risk of childhood-onset RRD and PVR. Proliferative vitreoretinopathy in turn increases the risk of recurrent RRD and may lead to blindness. Recognizing the LRPAP1-related high myopia phenotype is important, and early childhood examination with additional close follow-up and prophylactic retinal laser should be considered.
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| 29. |
- Owolabi, Mayowa O., et al.
(författare)
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Gaps in Guidelines for the Management of Diabetes in Low- and Middle-Income Versus High-Income Countries : A Systematic Review
- 2018
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Ingår i: Diabetes Care. - : AMER DIABETES ASSOC. - 0149-5992 .- 1935-5548. ; 41:5, s. 1097-1105
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Forskningsöversikt (refereegranskat)abstract
- OBJECTIVE The extent to which diabetes (DM) practice guidelines, often based on evidence from high-income countries (HIC), can be implemented to improve outcomes in low-and middle-income countries (LMIC) is a critical challenge. We carried out a systematic review to compare type 2 DM guidelines in individual LMIC versus HIC over the past decade to identify aspects that could be improved to facilitate implementation. RESEARCH DESIGN AND METHODS Eligible guidelines were sought from online databases and websites of diabetes associations and ministries of health. Type 2 DM guidelines published between 2006 and 2016 with accessible full publications were included. Each of the 54 eligible guidelines was assessed for compliance with the Institute of Medicine (IOM) standards, coverage of the cardiovascular quadrangle (epidemiologic surveillance, prevention, acute care, and rehabilitation), translatability, and its target audiences. RESULTS Most LMIC guidelines were inadequate in terms of applicability, clarity, and dissemination plan as well as socioeconomic and ethical-legal contextualization. LMIC guidelines targeted mainly health care providers, with only a few including patients (7%), payers (11%), and policy makers (18%) as their target audiences. Compared with HIC guidelines, the spectrum of DM clinical care addressed by LMIC guidelines was narrow. Most guidelines from the LMIC complied with less than half of the IOM standards, with 12% of the LMIC guidelines satisfying at least four IOM criteria as opposed to 60% of the HIC guidelines (P < 0.001). CONCLUSIONS A new approach to the contextualization, content development, and delivery of LMIC guidelines is needed to improve outcomes.
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| 30. |
- Ye, S. -Y, et al.
(författare)
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Dust Observations by the Radio and Plasma Wave Science Instrument During Cassini's Grand Finale
- 2018
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Ingår i: Geophysical Research Letters. - : AMER GEOPHYSICAL UNION. - 0094-8276 .- 1944-8007. ; 45:19, s. 10101-10109
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Tidskriftsartikel (refereegranskat)abstract
- Dust particles in the Saturn system can be detected by the Radio and Plasma Wave Science (RPWS) instrument on board Cassini via antenna voltage signals induced by dust impacts. These impact signals have been simulated in the laboratory by accelerating dust particles onto a Cassini model with electric field antennas. RPWS dust measurements have been shown to be consistent with the Cosmic Dust Analyzer. During the Grand Finale orbits, Cassini flew through the gap between the D ring and Saturn's atmosphere 22 times. In situ measurements by RPWS helped quantify the hazards posed to the spacecraft and instruments on board, which showed a micron-sized dust density orders of magnitude lower than that observed during the Ring Grazing orbits. Close inspection of the waveforms indicated a possible dependence of the impact signal decay time on ambient plasma density. Plain Language Summary Cassini flew through the gap between Saturn and its rings for 22 times before plunging into the atmosphere of Saturn, ending its 20-year mission. The radio and plasma waves instrument on board Cassini helped quantify the dust hazard in this previously unexplored region. The measured density of large dust particles was much lower than expected, allowing high-value science observations during the subsequent Grand Finale orbits.
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