| 1. |
|
|
| 2. |
|
|
| 3. |
- Gullberg, Cecilia, et al.
(author)
-
Institutional Complexity in Schools : Reconciling Clashing Logics Through Technology?
- 2020
-
In: Scandinavian Journal of Public Administration. - : Göteborgs universitet. - 2001-7405 .- 2001-7413. ; 24:1, s. 49-71
-
Journal article (peer-reviewed)abstract
- The article analyses the introduction and use of an IT platform in two Swedish schools. The aim is to examine the role of information systems in shaping institutional complexity, and the research questions addressed are: what logics are manifested through the use of the system and how do they interact with each other in relation to teachers’ emerging work practices? The article is based on a qualitative case study of how teachers and principals perceive and use the system, and it combines theoretical thinking on institutional logics and complexity with ideas on materiality and its role in organisational change. An analysis of three teacher practices that are emerging with use of the system enables a discussion of the presence and, notably, interplay of three primary logics. Logics of professionalism, bureaucracy and management are shown to interrelate in competitive but, primarily, cooperative ways. The very materiality of the IT system is shown to attenuate experiences of incompatibilities between logics and facilitate the management of different logics when they are actually perceived to be incompatible. Contrary to what much previous literature on institutional complexity in the field of education suggests, we therefore argue that institutional complexity may facilitate and enrich teachers’ practices instead of merely constituting a hindrance.
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
- Nilsson, Jenny, et al.
(author)
-
Influence of Age and Sex on Disease Course and Treatment in Rheumatoid Arthritis
- 2021
-
In: Open Access Rheumatology-Research and Reviews. - 1179-156X. ; 13, s. 123-138
-
Journal article (peer-reviewed)abstract
- Objective: More than 50% of patients with rheumatoid arthritis (RA) are >65 years at diagnosis. Age of onset and sex may influence the disease course, outcome and treatment. This study follows a large cohort of patients with early RA to assess contributions of age and sex to disease outcomes. Methods: Patients from the BARFOT cohort, n=2837 (68% women), were followed for eight years at predefined time points to assess inflammation, function, joint destruction and treatment with disease modifying anti-rheumatic drugs (DMARDs) and glucocorticoids (GC). The patients were divided by sex and age at inclusion (<40, 40-54, 55-69 and >= 70 years). Results: For both sexes, disease activity, function and pain improved over time, significantly more in men than in women in all age groups. In men, those <40 years displayed significantly lower DAS28 compared with all other groups. This group was also the least represented group in the study. The Sharp van der Heijde Score (SHS) increased over time in both sexes and all age groups. Women >= 70 years showed less improvement in disability and the highest progression of SHS mainly due to increased joint space narrowing. Patients <40 years were more likely to receive biological DMARDs, while those >= 70 years more often received only GC treatment. Conclusion: There were significant age- and sex-dependent differences in the medical treatment and in outcome of RA 8 years after diagnosis. The differences were most pronounced in men<40 and women >= 70 years, but whether they are due to disease phenotype or treatment is unclear.
|
|
| 9. |
- Pelaseyed, Thaher, 1979, et al.
(author)
-
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
- 2014
-
In: Immunological Reviews. - : Wiley. - 0105-2896 .- 1600-065X. ; 260:1, s. 8-20
-
Research review (peer-reviewed)abstract
- The gastrointestinal tract is covered by mucus that has different properties in the stomach, small intestine, and colon. The large highly glycosylated gel-forming mucins MUC2 and MUC5AC are the major components of the mucus in the intestine and stomach, respectively. In the small intestine, mucus limits the number of bacteria that can reach the epithelium and the Peyer's patches. In the large intestine, the inner mucus layer separates the commensal bacteria from the host epithelium. The outer colonic mucus layer is the natural habitat for the commensal bacteria. The intestinal goblet cells secrete not only the MUC2 mucin but also a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. The goblet cells have recently been shown to have a novel gate-keeping role for the presentation of oral antigens to the immune system. Goblet cells deliver small intestinal luminal material to the lamina propria dendritic cells of the tolerogenic CD103+ type. In addition to the gel-forming mucins, the transmembrane mucins MUC3, MUC12, and MUC17 form the enterocyte glycocalyx that can reach about a micrometer out from the brush border. The MUC17 mucin can shuttle from a surface to an intracellular vesicle localization, suggesting that enterocytes might control and report epithelial microbial challenge. There is communication not only from the epithelial cells to the immune system but also in the opposite direction. One example of this is IL10 that can affect and improve the properties of the inner colonic mucus layer. The mucus and epithelial cells of the gastrointestinal tract are the primary gate keepers and controllers of bacterial interactions with the host immune system, but our understanding of this relationship is still in its infancy.
|
|
| 10. |
- Sjöholm, Kajsa, 1971, et al.
(author)
-
A microarray search for genes predominantly expressed in human omental adipocytes: adipose tissue as a major production site of serum amyloid A.
- 2005
-
In: Journal of Clinical Endocrinology & Metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 90:4, s. 2233-9
-
Journal article (peer-reviewed)abstract
- To identify genes predominantly expressed in omental adipocytes, microarray expression profiles from 33 human tissues or cell types were analyzed, using an algorithm developed for identification of transcripts predominantly expressed in a certain tissue. Both known adipocyte-specific and more unexpected genes were among the 28 genes identified. To validate the approach, adipocyte expression of three of these genes, acute-phase serum amyloid A (A-SAA), aquaporin 7, and transport secretion protein-2.2, was compared with 17 other human tissues by real-time PCR. The unexpectedly high expression of A-SAA in adipocytes was further verified by Northern blot and immunohistochemistry. The liver, reported to be the main production site for A-SAA, displayed the second highest expression using microarray and real-time PCR. In obese subjects, adipose tissue mRNA and serum A-SAA levels were down-regulated during an 18-wk diet regime (P < 0.05 and P < 0.0001, respectively). A-SAA serum levels were highly correlated to adipose tissue mRNA levels (P < 0.001) and to the total (P < 0.0001) and sc (P < 0.0001) adipose tissue areas, as analyzed by computed tomography. We show that adipose tissue is a major expression site of A-SAA during the nonacute-phase reaction condition. This provides a direct link between adipose tissue mass and a marker for low-grade inflammation and cardiovascular risk.
|
|
| 11. |
|
|
| 12. |
- Svensson, Jenny, 1977-
(author)
-
Offentligt etos
- 2013
-
In: I det offentligas tjänst. - Malmö : Gleerups Utbildning AB. - 9789140682697 ; , s. 91-107
-
Book chapter (other academic/artistic)
|
|
| 13. |
- Svensson, Jenny, 1977-, et al.
(author)
-
Policy change as institutional work : Introducing cultural and creative industries into cultural policy
- 2017
-
In: Qualitative research in organization and management. - : Emerald Group Publishing Limited. - 1746-5648 .- 1746-5656. ; 12:2, s. 149-168
-
Journal article (peer-reviewed)abstract
- Purpose: Policy change is frequently framed as resulting from governmental strategy based on explicit preferences, rational decision making and consecutive and aligned implementation. The purpose of this paper is to explore the theoretical perspective of institutional work as an alternative approach to understanding policy change, and investigates the construction of resources needed to perform such work.Design/methodology/approach: The paper is based on a case study of the process wherein the idea of cultural and creative industries was introduced into Lithuanian cultural policy. The main data generating methods are document studies and qualitative interviews.Findings: The analysis demonstrates the ways in which the resources needed to perform institutional work are created through the enactment of practice, and through the application of resourcing techniques. Three such techniques are identified in the empirical material: the application of experiences from other fields of practice, the elicitation of external support, and the borrowing of legitimacy.Originality/value: The study offers an alternative approach to studies of policy change by demonstrating the value of institutional work in such change. Further, it contributes to the literature on institutional work by highlighting how instances of such work, drawing on a distributed agency, interlink and connect to each other in a process to produce policy change. Finally, it proposes three interrelated resourcing techniques underlying institutional work.
|
|
| 14. |
- Svensson, Jenny, 1977-
(author)
-
The Regulation of Rule-Following : Imitation and Soft Regulation in the European Union
- 2009
-
Doctoral thesis (other academic/artistic)abstract
- Present times are sometimes referred to as "the golden era of regulation", as more and more areas of social life are regulated. But regulation is not only increasing; it is also changing. New regulators are emerging, and they are issuing new kinds of rules. These new kinds of regulation are frequently not legally binding, and are therefore labelled soft regulation as opposed to hard law. It is not compulsory to follow soft rules but many actors - including sovereign states - still do, and the thesis asks the question why this is so. Why do even states, which are powerful regulators themselves, abide by soft regulation, and wherein lies the regulative power of soft rules? Through an in-depth study of the European Union's pre-accession instrument Twinning an answer to the question of the power of soft regulation has been arrived at. Treating Twinning as a critical case of soft regulation, and using theories of imitation to grasp the meaning and evolution of Twinning projects, makes it possible to define three regulative elements involved in soft regulation. These are the combinative, co-productive and constitutive elements of soft regulation, from which the thesis suggests that it derives its power. First of all, soft regulation combines different kinds of rules, the regulation of identity and the regulation of activity, and a variety of sources of legitimacy. Second, it depends on regulators and regulatees interacting to co-produce regulation. And third, as its main result, it constitutes the rule-followers as formal, rational, and modern organisations. Accordingly, soft regulation has rather impressive regulative capabilities, builds on complex, dynamic, and social interactions, and embodies as well as promotes some of Western society's most strongly institutionalised ideas. The thesis argues that it is through these characteristics that actors, including states, are compelled to follow soft rules.
|
|
| 15. |
- Svensson, Jenny, 1977-
(author)
-
Varför är det så många som granskar så mycket?
- 2017
-
In: Organisation & Samhälle. - : Föreningen Företagsekonomi i Sverige. - 2001-9114 .- 2002-0287. ; :1, s. 28-33
-
Journal article (other academic/artistic)
|
|
