| 1. |
- McCamish-Svensson, C, et al.
(författare)
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Informal and formal support from a multi-disciplinary perspective: a Swedish follow-up between 80 and 82 years of age
- 1999
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Ingår i: Health & Social Care in the Community. - 0966-0410. ; 7:3, s. 163-163
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Tidskriftsartikel (refereegranskat)abstract
- This longitudinal study used a multi-disciplinary approach and examined the relationship between psychosocial and health characteristics and the pattern of informal and formal support for non-institutionalized very old people. The data were derived from a single cohort of 80-year-old people living in Lund, Sweden who were followed over a 3-year period. In order to account for potential sample bias, an analysis at 80 years measured the differences between the participants who were measured at both test periods, the drop-outs who discontinued from the study prior to 82 years, and the deceased who died prior to 82 years (n = 212). Results revealed that the groups differed significantly according to reported number of children and health measures: the participants were most likely to have children and exhibited the best health. Bivariate analyses examined social, psychological and health variables for survivors (n = 93) at both 80 and 82 years in relationship to independent, informal, and formal support type. Loneliness was significantly and consistently associated with support type at both 80 and 82 years: both frequency and strength of loneliness were most often reported in the formal support group. Depression was significantly related to support type at age 80 only. Looking at change in the psychosocial and health measures and change in support over the 3-year period, no significant relationships were found. Our study concludes that for the very old, in addition to requiring increased support over a 3-year period, loneliness is a significant characteristic that may accompany the receipt of support. Professionals who plan and implement social support programmes for elderly persons should also consider emotional and psychological needs.
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| 2. |
- McCamish-Svensson, C, et al.
(författare)
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Social relationships and health as predictors of life satisfaction in advanced old age: results from a Swedish longitudinal study
- 1999
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Ingår i: International Journal of Aging and Human Development. - 0091-4150. ; 48:4, s. 301-324
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Tidskriftsartikel (refereegranskat)abstract
- This longitudinal study examines the relationship between family and friend social support, health, and life satisfaction for a single cohort of eighty-year-old persons living in Lund, Sweden. Results indicate that participants who remained in the study are healthier and score higher on life satisfaction when compared with those who either drop-out or die prior to age eighty-three. Even though well-integrated with family and friends, the number of friends decreases significantly from eighty to eighty-three years; those who reported no close friends nearly doubled from eighty to eighty-three years. However, for those with close friends, contact with friends increases with age. In contrast to previous research, a correlational analysis indicates that neither child nor friend support is related to life satisfaction at either eighty or eighty-three years. However, health measures and satisfaction with sibling contact are related to total life satisfaction at age eighty-three only. These findings indicate the multidimensionality of both social support and life satisfaction for the old-old.
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| 3. |
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| 4. |
- Tyler, Torbjörn, et al.
(författare)
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Utsådda blommor räddar inte insekterna
- 2021
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Ingår i: Svenska Dagbladet. - 1101-2412.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Om vi vill rädda hotade insektsarter är det miljöer med traditionella ängsväxter som vi behöver mer av, inte fröblandningar av oklart ursprung från handeln. Det skriver flera debattörer.
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| 5. |
- Aarnio, Harri, et al.
(författare)
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Recombination studies in a polyfluorene copolymer for photovoltaic applications
- 2005
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Ingår i: Synthetic Metals. - : Elsevier BV. - 0379-6779. ; 155:2, s. 299-302
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Tidskriftsartikel (refereegranskat)abstract
- We present detailed continuous wave (cw) and transient photoinduced absorption (PA) measurements in thin films of a novel alternating polyfluorene copolymer, poly[2,7-(9,9-dioctyl-fluorene)-alt-5,5-(4',7'-di-2-thienyl-2',1',3-benzo-thiadiazole)] (DiO-PFDTBT), and its blends with the sol. fullerene deriv. [6,6]-phenyl-C61-butyric acid Me ester (PCBM) in wt. ratios of 1:0, 4:1 and 1:4. We measure the frequency, intensity and temp. dependence of the PA signal in the frequency domain, and compare with the results obtained from the transient PA decay measurements in the time domain. In all blends, the PA spectrum shows a broad high energy PA band ranging from .apprx.1 eV to 2 eV as well as a low energy band peaking at .apprx.0.35 eV. We attribute the low energy band to the P1 transition of polarons and part of the high energy band to the correlated P2 transition of polarons. Both frequency and time domain measurements show that the high energy band has two decay components, a faster component in the microsecond time regime and a slower component in the millisecond time regime. The slow component is strongly dispersive, whereas the fast component is practically non-dispersive. [on SciFinder (R)]
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| 6. |
- Abdulahovic, Tarik, 1976, et al.
(författare)
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Simulation accuracy of the built-in PSCAD and an owner-defined synchronous machine model
- 2010
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Ingår i: COMPEL - The International Journal for Computation and Mathematics in Electrical and Electronic Engineering. - : Emerald. - 0332-1649. ; 29:3, s. 840-855
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Tidskriftsartikel (refereegranskat)abstract
- Purpose - The purpose of this paper is to investigate the influence of time steps, integration methods, and saturation modeling on the accuracy of the synchronous machine model. This model is compared with the PSCAD built-in synchronous machine model in order to compare the accuracy of one of the most used synchronous machine models in a commercially available software versus a well-documented and widely accepted state-space synchronous machine model. Design/methodology/approach - In the paper, a synchronous condenser with the saturation phenomenon is modeled using state-space equations in the rotating dq-reference frame and is implemented both in Matlab/Simulink and PSCAD. Integration methods of up to the fifth order are implemented for increased accuracy. The saturation modeling includes modeling of the saturation in both d- and q-axis. A steady-state and dynamic performance comparison towards the built-in PSCAD synchronous machine model is performed. The saturation modeling does not include the saturation of the leakage fluxes. Findings - When the forward Euler method is used, in order to obtain less than 5 percent error, the time step should not exceed 5 its. The third-order Runge-Kutta method is the preferred choice and it provides desired accuracy when the time step is equal or smaller than 1,000 its. The built-in PSCAD model satisfies the error criteria for time steps smaller than 300 its. A small discrepancy of 2 percent is found during the steady-state test. Originality/value - The paper presents the performance of the higher order integration methods in an EMTP-type software environment where the trapezoidal integration method is most often used. It provides a good guide for building an owner-defined model. A comparison of a dynamic performance between the publicly documented state-space and a synchronous machine models commonly used for power system transient studies is presented.
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| 7. |
- Abel, I, et al.
(författare)
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Overview of the JET results with the ITER-like wall
- 2013
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 53:10, s. 104002-
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Tidskriftsartikel (refereegranskat)abstract
- Following the completion in May 2011 of the shutdown for the installation of the beryllium wall and the tungsten divertor, the first set of JET campaigns have addressed the investigation of the retention properties and the development of operational scenarios with the new plasma-facing materials. The large reduction in the carbon content (more than a factor ten) led to a much lower Z(eff) (1.2-1.4) during L- and H-mode plasmas, and radiation during the burn-through phase of the plasma initiation with the consequence that breakdown failures are almost absent. Gas balance experiments have shown that the fuel retention rate with the new wall is substantially reduced with respect to the C wall. The re-establishment of the baseline H-mode and hybrid scenarios compatible with the new wall has required an optimization of the control of metallic impurity sources and heat loads. Stable type-I ELMy H-mode regimes with H-98,H-y2 close to 1 and beta(N) similar to 1.6 have been achieved using gas injection. ELM frequency is a key factor for the control of the metallic impurity accumulation. Pedestal temperatures tend to be lower with the new wall, leading to reduced confinement, but nitrogen seeding restores high pedestal temperatures and confinement. Compared with the carbon wall, major disruptions with the new wall show a lower radiated power and a slower current quench. The higher heat loads on Be wall plasma-facing components due to lower radiation made the routine use of massive gas injection for disruption mitigation essential.
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| 12. |
- Alvarez Díaz, María Guadalupe, et al.
(författare)
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The Mystery of Elin : Incorporating a City Cultural Program on History and Heritage into a Pervasive Game
- 2014
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Ingår i: IE2014 Proceedings of the 2014 Conference on Interactive Entertainment. - New York, NY, USA : ACM Digital Library. - 9781450327909 ; , s. 1-10
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Konferensbidrag (refereegranskat)abstract
- This paper reports on the use of mobile terminals in historical spaces to play an adventure game, using a location-based platform to awaken the fantasy and curiosity of children about cultural heritage; the design of a mystery game as the medium to convey content along with features shared by pervasive games, such as mobile exploration, team work, and the combination of virtual and real worlds. It includes the process of adapting history to storytelling and the results of using a method to evaluate the experience.
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| 13. |
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| 14. |
- Andersén, Jim, 1976-, et al.
(författare)
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Entrepreneurially oriented in what? A business model approach to entrepreneurship
- 2015
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Ingår i: Journal of Small Business and Enterprise Development. - : Emerald Group Publishing Limited. - 1462-6004 .- 1758-7840. ; 22:3, s. 433-449
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Tidskriftsartikel (refereegranskat)abstract
- Purpose – The purpose of this paper is to illustrate and argue for the necessity of deconstructing the entrepreneurship concept by analyzing entrepreneurial orientation (EO) at various levels of the business model.Design/methodology/approach – Literature review supplemented with five illustrative cases.Findings – A business model approach to entrepreneurship enables identification of the component of the business model in which entrepreneurship was started. This has several implications for analysis of the EO-performance relationship and for the identification of antecedents to EO.Originality/value – The EO of firms has generally been analyzed at a generic level, i.e. the concept has been used to measure and analyze the overall entrepreneurship of firms. In this paper, the authors argue that EO can be present in various dimensions of a business and that firms can be entrepreneurial in certain areas and conservative in other areas.
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| 15. |
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| 17. |
- Bacchetti, Tiziana, et al.
(författare)
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Effects of Seven Weeks of Combined Physical Training on High-Density Lipoprotein Functionality in Overweight/Obese Subjects
- 2023
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Ingår i: Metabolites. - : MDPI. - 2218-1989 .- 2218-1989. ; 13:10, s. 1068-1068
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Tidskriftsartikel (refereegranskat)abstract
- Our study aimed to investigate the effects of exercise on HDL composition and functional properties in overweight/obese subjects. Eighteen overweight/obese subjects (nine F and nine M, BMI = 30.3 ± 3 kg/m2) attended supervised training for 7 weeks. The protocol included combined resistance and conditioning training four to five times each week. The activity of the antioxidant enzyme paraoxonase-1 (PON1) associated with HDL was evaluated in all subjects before and after the training intervention. Moreover, myeloperoxidase (MPO) levels and oxidative stress markers (ox-LDLs and total antioxidant capacity) were studied in the serums of the subjects. At the end of the intervention, the activity of PON1 was increased (p < 0.0001), and MPO levels and the MPO/PON1 ratio were decreased (p < 0.0001). In addition, a significant improvement in muscle strength and maximal oxygen uptake (VO2max) (p < 0.0001) and a significant reduction in total and visceral adipose tissue mass (p < 0.001) and waist circumference (p < 0.008), without any significant decrease in body weight, were observed. A significant correlation was established between serum MPO/PON ratios, HDL redox activity and ox-LDLs. In conclusion, our results demonstrate that exercise training, without modifications of dietary habits, improved HDL functionality in overweight/obese adults, without any significant reduction in BMI or modifications of glucose and lipid biochemical parameters.
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| 18. |
- Berg, Cecilia, et al.
(författare)
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Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase.
- 2006
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Ingår i: Thrombosis and haemostasis. - 0340-6245. ; 96:5, s. 652-9
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Tidskriftsartikel (refereegranskat)abstract
- Proliferation of fibroblasts is vital for adequate wound healing but is probably also involved in different hyperproliferative disorders such as atherosclerosis and cancer. The regeneration of tissue usually starts with coagulation, involving release of mitogenic and inflammatory factors from activated platelets. This study focuses on the role of eicosanoids in the proliferative effects of platelets on human fibroblasts. We show that the phospholipase A (2) inhibitor 7,7-dimethyl-5,8-eicosadienoic acid (DMDA), the combined cyclooxygenase (COX) and lipoxygenase (LOX) inhibitor 5,8,11,14-eicosatetraynoic acid (ETYA) and the LOX inhibitor 5,8,11-eicosatriynoic acid (ETI) block the platelet-induced proliferation of serum starved subconfluent human fibroblasts. Anti-proliferative effects were also obtained by specific inhibition of 5-LOX with 5,6-dehydro arachidonic acid (5,6-dAA), whereas the 12-LOX inhibitor cinnamyl-3,4-dihydroxy- a -cyanocinnamate (CDC) did not affect the platelet-stimulated growth of fibroblasts. The expression of 5-LOX was analyzed by reverse-transcriptase-mediated PCR (RT-PCR), Western blotting and HPLC. 5-LOX message and protein was detected in fibroblasts but not in platelets. Incubation with platelets markedly increased, already after one hour, the expression of 5-LOX in the fibroblast culture. The increased 5-LOX activity was associated with an elevated level of the 5-LOX metabolite 5-hydroxyeicosatetraenoic acid (5-HETE) reaching its maximum after 1 - 2 hours of co-incubation of fibroblasts and platelets. The 5-HETE production was reduced by the inhibitors DMDA, ETYA and ETI. In conclusion, this study suggests that platelet-stimulated proliferation of fibroblasts is mediated by an increased 5-LOX activity, which supports recent findings indicating a crucial role for this enzyme in proliferative disorders such as atherosclerosis.
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| 19. |
- Berg, Cecilia, 1976-, et al.
(författare)
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Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase
- 2006
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Ingår i: Thrombosis and Haemostasis. - 0340-6245 .- 2567-689X. ; 96:5, s. 652-659
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Tidskriftsartikel (refereegranskat)abstract
- Proliferation of fibroblasts is vital for adequate wound healing but is probably also involved in different hyperproliferative disorders such as atherosclerosis and cancer. The regeneration of tissue usually starts with coagulation, involving release of mitogenic and inflammatory factors from activated platelets. This study focuses on the role of eicosanoids in the proliferative effects of platelets on human fibroblasts. We show that the phospholipase A2 inhibitor 7,7-dimethyl-5,8-eicosadienoic acid (DMDA), the combined cyclooxygenase (COX) and lipoxygenase (LOX) inhibitor 5,8,11,14-eicosatetraynoic acid (ETYA) and the LOX inhibitor 5,8,11-eicosatriynoic acid (ETI) block the platelet-induced proliferation of serum starved subconfluent human fibroblasts. Anti-proliferative effects were also obtained by specific inhibition of 5-LOX with 5,6-dehydro arachidonic acid (5,6-dAA), whereas the 12-LOX inhibitor cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) did not affect the platelet-stimulated growth of fibroblasts. The expression of 5-LOX was analyzed by reverse-transcriptase-mediated PCR (RT-PCR), Western blotting and HPLC. 5-LOX message and protein was detected in fibroblasts but not in platelets. Incubation with platelets markedly increased, already after one hour, the expression of 5-LOX in the fibroblast culture. The increased 5-LOX activity was associated with an elevated level of the 5-LOX metabolite 5-hydroxyeicosatetraenoic acid (5-HETE) reaching its maximum after 1-2 hours of co-incubation of fibroblasts and platelets. The 5-HETE production was reduced by the inhibitors DMDA, ETYA and ETI. In conclusion, this study suggests that platelet-stimulated proliferation of fibroblasts is mediated by an increased 5-LOX activity, which supports recent findings indicating a crucial role for this enzyme in proliferative disorders such as atherosclerosis. © 2006 Schattauer GmbH, Stuttgart.
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| 20. |
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| 31. |
- Borgestig, Maria
(författare)
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The impact of gaze-based assistive technology on daily activities in children with severe physical impairments
- 2016
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Aim: The aim of the thesis was to investigate the impact of gaze-based assistive technology on daily activities in children with severe physical impairments and without speech. The objectives were to develop and pilot a gaze-based assistive technology intervention (GAT intervention) at home and in school for these children and to understand its impact on daily activities as experienced by their parents.Methods: Study I was a pilot study in which the basic components that were developed for the intervention were evaluated for students with physical impairments. The study aimed at improving the use of computers as assistive technology (AT) in school. Based on the findings in Study I, the GAT intervention was developed. The GAT intervention aimed at implementing gaze-based AT in daily activities. It consisted of two parts; having access to gaze-based AT and having access to services from a multi professional communication team during nine to ten months. Studies II-IV concerned gazebased AT for children with severe physical impairments without speech who participated in the GAT intervention. The participants were ten children (ages 1-15) (Studies II, III), and their parents (Study IV). Studies II and III had longitudinal designs and children were followed during 15-20 months with repeated measurements before, after and at follow-up. In Study II children’s repertoire of computer activities, extent of use, and goal attainment with gaze-based AT was evaluated, as well as parents’ satisfaction with the AT and with services. In Study III children’s eye gaze performance when using gaze-based AT was examined. In Study IV, parents were interviewed twice with the aim of exploring their experiences of children’s gaze-based AT use in daily life. In Study IV a hermeneutical approach was used.Results: The findings of Study I showed that the basic components of intervention improved the use of computers in school. Study II showed an increased repertoire of computer activities with the gazebased AT, maintained use in daily activities for all at follow up, and that all children attained goals for gaze-based AT use in daily activities. Parents were satisfied with the gaze-based AT, and with the services in the GAT intervention. In study III, nine children improved in eye gaze performance over time when using the gaze-based AT in daily activities. Study IV revealed that children’s gaze-based AT usage in daily activities made a difference to parents since the children demonstrated agency, and showed their personality and competencies by using gaze-based AT, and for the parents this opened up infinite possibilities for the child to do and learn things. Overall, children’s gaze-based AT usage provided parents with hope of a future in which their children could develop and have influence in life.Conclusions: This thesis shows that these children with severe physical impairments and without speech acquired sufficient gaze control skills to use gaze-based AT for daily activities in the home and at school. The gaze-based AT had a positive impact on performing activities, for example, play activities and communication- and interaction-related activities. For the parents, children’s gaze-based AT usage made a difference since it shaped a hope of a better future for their children, where they can develop and gain influence in their future life. Furthermore, the children continued to perform daily activities with gaze-based AT over time. This finding suggests that key persons were provided with sufficient knowledge and skills to support children in maintained use of gaze-based AT after withdrawal of the services provided in the GAT intervention.
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| 32. |
- Brännström, André, et al.
(författare)
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Vitamin D in relation to bone health and muscle function in young female soccer players
- 2017
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Ingår i: European Journal of Sport Science. - : Informa UK Limited. - 1746-1391 .- 1536-7290. ; 17:2, s. 249-256
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Tidskriftsartikel (refereegranskat)abstract
- The present work investigated serum vitamin D (25(OH)D) status in relation to bone and muscle qualities and functions in 19 female soccer players (13–16 years) resident at northern latitude with very low sun exposure (∼32–36 h/month) during winter season (late January to early March). Serum 25(OH)D, parathyroid hormone and bone turnover markers osteocalcin (OC) and beta carboxy-terminal collagen cross-links (β-Ctx), as well as body composition and muscle performance were examined. Hormones were tested using routine laboratory methods. Fat mass, lean mass, and bone mineral density in whole body, as well as femur and lumbar spine were evaluated with dual-energy X-ray absorptiometry. Muscle performance was assessed through isokinetic knee extension and flexion, countermovement jump, and sprint running. 25(OH)D was low (50.5 ± 12.8 nmol l−1), whereas the values of bone turnover markers were markedly high (OC: 59.4 ± 18.6 μg l−1; β-Ctx: 1075 ± 408 ng l−1). All bone and muscle measurements were normal or above normal. 25(OH) D was not significantly correlated with most of the parameters of bone and muscle quality or function, except the knee extension time to peak torque (r = −0.50, p = .03). In conclusion, the level of vitamin D is markedly low in adolescent female soccer players during the winter in Sweden. However, vitamin D levels did not significantly correlate with measures of bone and muscle except a moderate correlation in time to peak torque in the knee extensors. The practical implication of low vitamin D levels in young growing female athletes remains unclear.
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| 33. |
- Bülow, B, et al.
(författare)
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The gender differences in growth hormone-binding protein and leptin persist in 80-year-old men and women and is not caused by sex hormones.
- 2003
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Ingår i: Clinical Endocrinology. - : Wiley. - 1365-2265 .- 0300-0664. ; 59:4, s. 6-482
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Tidskriftsartikel (refereegranskat)abstract
- objective Leptin and growth hormone-binding protein (GHBP) both show gender differences that might be explained by sex hormones. To study the potential relevance of oestradiol and testosterone, we have examined 80-year-old subjects in whom oestradiol is higher in men than in women. The interrelationships between leptin, insulin, GHBP and fat mass in this age group were also investigated. design and subjects Ninety-four subjects (55 females and 39 males), all 80 years old, were investigated in a community-based study. None of the investigated subjects was being treated for diabetes mellitus and none of the women had oestrogen replacement. methods Levels of testosterone, oestradiol, SHBG, IGF-I, GHBP, glucose, insulin and leptin were analysed. Body composition was measured with bioimpedance analysis (BIA). results As in younger age groups, serum leptin, the ratio leptin/kilogram fat mass and serum GHBP were higher in the women (all, P <= 0·007), although serum oestradiol was higher in the men (P < 0·001). There were no significant associations between sex hormones and leptin or GHBP either in women or in men (all, r < 0·13, P > 0·1). Leptin correlated to kilogram fat mass in both women (r = 0·55, P < 0·001) and men (r = 0·47, P = 0·003), but in contrast, there were no significant correlations between GHBP and fat mass and GHBP and IGF-I, either in women or in men (all, r < 0·24, P > 0·2). Insulin and leptin were significantly associated with GHBP, both in women (r = 0·48, P < 0·001 and r = 0·43, P = 0·001, respectively) and in men (r = 0·40, P = 0·01 and r = 0·34, P = 0·03, respectively). conclusions Although the 80-year-old men had higher oestradiol levels than the women, the women had higher levels of leptin and GHBP. There were no correlations between sex hormones and leptin and GHBP, which indicates that the gender differences are not caused by sex hormones in old age. In contrast to studies in younger subjects, GHBP did not correlate to fat mass in the investigated 80-year-old men and women. In the older subjects investigated, as in younger subjects, GHBP was significantly correlated with leptin and insulin.
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| 34. |
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| 35. |
- Cantatore, Valentina, 1986, et al.
(författare)
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Oxidation Driven Permeation of Iron Oxide Scales by Chloride from Experiment Guided First-Principles Modeling
- 2019
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Ingår i: Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 123:42, s. 25957-25966
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Tidskriftsartikel (refereegranskat)abstract
- In this comprehensive investigation, it is demonstrated how chloride ions may permeate a crack-free oxide scale, thus providing hitherto missing mechanistic insight as to the impacts of KCl(s) or HCl(g) exposures on the high-temperature corrosion of biomass- and waste-fired boilers. Guided by dedicated experimental analyses, mechanistic understanding is gained by means of density functional theory. Chloride ions, being accommodated in oxygen anion vacancies that are generated at the receding magnetite/alloy interface, are driven through the oxide scale by the oxidation process. Intermediate stabilities of quasi-homogeneous transient iron oxychloride species are found, employing potassium ferrite and goethite as complementary cation sinks for the KCl(s) and HCl(g) reactants, respectively. Spontaneous disproportionation of the supersaturated oxychlorides into two different types of chloride decorated magnetite grain boundaries is demonstrated. These motifs are proposed to explain loss of scale integrity as well as accelerated oxidation by offering short-circuiting transient pathways for ion diffusion.
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| 36. |
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| 37. |
- Chiatti, Carlos, et al.
(författare)
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ISSA 2012 : The medium-term impact of the first ISSA in the eyes of its participants
- 2015
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Ingår i: Irish Ageing Studies Review. - 1649-9972. ; 6:1, s. 44-44
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Tidskriftsartikel (refereegranskat)abstract
- Background: This contribution aims at illustrating the perspective of students attending the first International Summer School on Ageing (ISSA), highlighting the midterm impact exerted by this initiative on their own educational career.Methods: The reported findings are based on a follow-up assessment questionnaire sent out to and filled-in by ISSA participants (n= 20) six months after the Summer School’s conclusion, with the aim of identifying whether participation in the ISSA had brought any advantage to each participant's professional and educational life.Results: Among the ISSA-related aspects identified as “important” for their future research activity, the main ones were “interacting with established researchers” (100%) and “being part of a research network” (85%), followed by “use of different approaches” and “training environment”. As for the aspects “influenced” by the ISSA, the “development of a professional network” was the most frequently mentioned (100%), followed by “research training” (84%), “research interest” (79%) and “career” (71%). The majority of participants reported that, since their ISSA attendance, had remained in contact with each other for study-related (65%) or work-related (60%) purposes. This networking activity has led to joint scientific collaborations with both mentors (one joint conference presentation and two peer-review publications) and fellow students (preparation of a project proposal in response toa research call and organisation of a scientific event).Conclusions: The reported findings show that the ISSA has been useful in creating a collaborative multidisciplinary network of younger and older researchers on ageing-related issues, which is likely to bear more fruitin the long-term.
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| 38. |
- Christensen, Torben, et al.
(författare)
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Thawing sub-arctic permafrost : Effects on vegetation and methane emissions
- 2004
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Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 31:4
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Tidskriftsartikel (refereegranskat)abstract
- Ecosystems along the 0degreesC mean annual isotherm are arguably among the most sensitive to changing climate and mires in these regions emit significant amounts of the important greenhouse gas methane (CH4) to the atmosphere. These CH4 emissions are intimately related to temperature and hydrology, and alterations in permafrost coverage, which affect both of those, could have dramatic impacts on the emissions. Using a variety of data and information sources from the same region in subarctic Sweden we show that mire ecosystems are subject to dramatic recent changes in the distribution of permafrost and vegetation. These changes are most likely caused by a warming, which has been observed during recent decades. A detailed study of one mire show that the permafrost and vegetation changes have been associated with increases in landscape scale CH4 emissions in the range of 22-66% over the period 1970 to 2000.
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| 39. |
- Christesen, Henrik Thybo, et al.
(författare)
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Tissue variations of mosaic genome-wide paternal uniparental disomy and phenotype of multi-syndromal congenital hyperinsulinism
- 2020
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Ingår i: European Journal of Medical Genetics. - : Elsevier BV. - 1769-7212 .- 1878-0849. ; 63:1
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Tidskriftsartikel (refereegranskat)abstract
- Mosaic genome-wide paternal uniparental disomy (GW-pUPD) is a rarely recognised disorder. The phenotypic manifestations of multilocus imprinting defects (MLIDs) remain unclear. We report of an apparently non-syndromic infant with severe congenital hyperinsulinism (CHI) and diffuse pancreatic labelling by 18F*-DOPA-PET/CT leading to near-total pancreatectomy. The histology was atypical with pronounced proliferation of endocrine cells comprising >70% of the pancreatic tissue and a small pancreatoblastoma. Routine genetic analysis for CHI was normal in the blood and resected pancreatic tissue. At two years’ age, Beckwith-Wiedemann Syndrome (BWS) stigmata emerged, and at five years a liver tumour with focal nodular hyperplasia and an adrenal tumour were resected. pUPD was detected in 11p15 and next in the entire chromosome 11 with microsatellite markers. Quantitative fluorescent PCR with amplification of chromosome-specific DNA sequences for chromosomes 13, 18, 21 and X indicated GW-pUPD. A next generation sequencing panel with 303 SNPs on 21 chromosomes showed pUPD in both blood and pancreatic tissue. The mosaic distribution of GW-pUPD ranged from 31 to 35% in blood and buccal swap to 74% in the resected pancreas, 80% in a non-tumour liver biopsy, and 100% in the liver focal nodular hyperplasia and adrenal tumour. MLID features included transient conjugated hyperbilirubinaemia and lack of macrosomia from BWS (pUPD6); and behavioural and psychomotor manifestations of Angelman Syndrome (pUPD15) on follow-up. In conclusion, atypical pancreatic histology in apparently non-syndromic severe CHI patients may be the first clue to BWS and multi-syndromal CHI from GW-pUPD. Variations in the degree of mosaicism between tissues explained the phenotype.
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| 40. |
- Edstedt, Lars, 1981-
(författare)
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Mellan åtal och dom : Om underlaget och ramarna för rättens bedömning av frågorna om skuld, rubricering och påföljd
- 2024
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Between Indictment and Judgment. On the Basis for and the Limits of the Court’s Assessmentof Questions Concerning Guilt, Legal Qualification and Sentence.This study concerns the relationship between the indictment and the judgment in Swedish criminal procedure. Three central aspects of the criminal judgment are covered: The question of the accused’s guilt (the alleged criminal act in the indictment), the legal qualification of the offence and the sentence. The rule governing this relationship, between indictment and judgment, can be found in Chapter 30 paragraph 3 of the Swedish Code of Judicial Procedure. The requirements on the contents of the indictment are carefully examined, as well as other procedural acts, by the accused and by the court itself through its direction of the proceedings, that can have an effect on the limits of the court’s examination of criminal cases.Two questions of paramount importance are covered in-depth: How detailed must the indictment be (and what are the consequences of vagueness in the indictment)? And how should the principle that the court is bound by the indictment be interpreted? It is argued that a flexible standard for the indictment should be applied, allowing different legal consequences for varying deficiencies. With regard to the court being bound by the indictment, is argued that the theory of literary interpretation of the indictment is flawed, and that the demands of the principle of contradictory proceedings should determine the boundaries of the criminal act in the indictment.The study also contains a comprehensive examination of the case-law of the European Court of Human Rights concerning the right of the accused to be informed of the natureand cause of the accusation, contained in Article 6 § 3 (a) of the European Convention of Human Rights.The material rules of immediate interest are explored against the backdrop of a lengthy investigation into their historical and ideological underpinnings. The history of Swedish criminal procedure is described, as well as various theoretical developments. In particular, the question if Swedish criminal procedure should best be described as inquisitorial or accusatorial/adversarial and questions concerning the function of criminal procedure are investigated.
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| 41. |
- Edvall Malm, Disa, 1965-
(författare)
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Det socio-polisiära handlingsnätet : om kopplingar mellan polis och socialtjänst kring ungdomars kriminalitet och missbuk
- 2012
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Övergripande diskuterar avhandlingen olika aspekter av att samhällets system av stöd och kontroll för barn och unga knyts närmare samman. Det handlar om hur samverkan framställs och uppfattas på olika nivåer och hur den konkretiseras i polisens och socialtjänstens arbete kring unga som utvecklat eller bedöms riskera att utveckla kriminalitet och/eller missbruk. Studieobjektet inbegriper övergripande ideologisknivå, lokal/praktisknivå och individuell nivå. Syftet med avhandlingen är att identifiera, beskriva och analysera polisens och socialtjänstens samverkan kring barn och ungas kriminalitet och missbruk. Utgångspunkten är hur; samverkan mellan myndigheterna framställs i offentliga dokument, hur lokala aktörer uppfattar behovet av men också möjligheter, svårigheter och hinder kring samverkan, hur myndigheterna lokalt är organiserade för att aktualisera, handlägga, behandla och avsluta barn och unga, och slutligen vilka barn och unga som denna samverkan kan omfatta. Avsikten är att få en bild av vad denna samverkan på policynivå innebär och sätta detta i relation till hur polis och socialtjänst förstår och skapar sina respektive och gemensamma uppdrag i förhållande till varandra lokalt. I avhandlingen används tre olika empiriska material och olika metoder för analys: Analys av statliga offentliga dokument, kvalitativa intervjuer med poliser, socialarbetare och deras chefer i en kommun och en kvantitativ kartläggning av aktuella ungdomar i kommunen. Handlingsnät som teoretisk grund används för att studera kopplingar mellan de båda myndigheterna och de tre olika nivåerna av studien. Genom att använda handlingsnät blir det möjligt att se hur polisens och socialtjänstens olika uppdrag kopplas samman kring barn och ungas kriminalitet och missbruk.Resultaten av studien visar att det pågår en ettablering av ett socio-polisiärt handlingsnät på den övergripande ideologiska nivån och den lokala kommunala nivån. I policydokumenten förspråkas ett kontrollerande förhållningsätt gentemot ungas kriminalitet. På den lokala nivån handlade det om ett kontrollstödjande förhållningsätt för att motverka både ungas kriminalitet och missbruk. Resultaten av studien visar att socialtjänsten fått ta ett större ansvar för att utreda och verkställa påföljder för ungas kriminella handlingar, samtidigt som det inom socialtjänsten riskerar att utvecklas en logik mera baserad på straffvärdet av den brottsliga handlingen än den unges individuella behov av hjälp och stöd. Studien visar att i polisens och sociatjänstens arbete med enskilda barn och unga finns få möjligheter till samarbete. Dessutom var det få unga personer som samtidigt var aktuella för både polis och socialtjänst, vilket gör det svårt att uppnå något djupare längre samarbete kring enskilda ungdomar under längre tid. Det kan i bästa fall mera handla om en form av remissförfarande från polis till socialtjänst.
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| 42. |
- Eklund, Johan, 1991, et al.
(författare)
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Field exposure of FeCrAl model alloys in a waste-fired boiler at 600°C: The influence of Cr and Si on the corrosion behaviour
- 2019
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Ingår i: Materials and Corrosion. - : Wiley. - 0947-5117 .- 1521-4176. ; 70:8, s. 1476-1485
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Tidskriftsartikel (refereegranskat)abstract
- Materials and Corrosion WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim The aim of this study was to examine the performance of FeCrAl model alloys in a waste-fired boiler and investigate the influence of chromium and silicon content on the corrosion behaviour. The investigation was executed by utilising an air-cooled probe, giving a material temperature of 600°C throughout a 672 hr exposure. The material loss measurements were performed by utilizing an ultrasonic thickness gauge in combination with scanning electron microscopy analysis. It was found that increasing the chromium content significantly reduced the overall material loss of the FeCrAl model alloys but further accelerated the corrosion attack on the windward side. Simultaneously, the increased chromium content caused embrittlement of the material. Minor additions of silicon drastically reduced the material loss of the FeCrAl model alloys, whereas the sample ring with no silicon present was completely deteriorated. The trends observed in this field study correlated well with what has been observed in previous laboratory studies. A state-of-the-art alloy in the present environment, Inconel 625, was simultaneously exposed and showed similar performance to the silicon-containing FeCrAl model alloys with ≥10 wt% Cr.
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| 43. |
- Eklund, Johan, 1991, et al.
(författare)
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The influence of silicon on the corrosion properties of FeCrAl model alloys in oxidizing environments at 600 °C
- 2018
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Ingår i: Corrosion Science. - : Elsevier BV. - 0010-938X. ; 144, s. 266-276
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Tidskriftsartikel (refereegranskat)abstract
- The present study investigates the influence of Si on the high temperature corrosion behaviour of FeCrAl model alloys in O2, O2+H2O and O2+H2O + KCl at 600 °C for up to 168 h. The investigation by SEM/EDX showed that all alloys displayed a protective behaviour in dry O2. In the more corrosive environments (O2+H2O and O2+H2O + KCl) the addition of Si affected the oxidation properties in two ways; Alloys containing Si resisted breakaway oxidation caused by Cr-evaporation (O2+H2O) and the thickness of the oxide formed after breakaway oxidation decreased with increasing amount of Si (O2+H2O + KCl).
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| 44. |
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| 45. |
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| 46. |
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| 47. |
- Erixon, Martin, et al.
(författare)
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Take care in how you store your PD fluids: Actual temperature determines the balance between reactive and non-reactive GDPs
- 2005
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Ingår i: Peritoneal Dialysis International. - 1718-4304. ; 25:6, s. 583-590
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Tidskriftsartikel (refereegranskat)abstract
- Objective: During heat sterilization and during prolonged storage, glucose in peritoneal dialysis fluids (PDF) degrades to carbonyl compounds commonly known as glucose degradation products (GDPs). Of these, 3,4-dideoxyglucosone-3-ene (3,4-DGE) is the most cytotoxic. It is an intermediate in degradation between 3-deoxyglucosone (3-DG) and 5-hydroxymethyl-2-furaldehyde (5-HMF). We have earlier reported that there seems to be equilibrium between these GDPs in PDF. The aim of the present study was to investigate details of this equilibrium. Methods: Aqueous solutions of pure 3-DG, 3,4-DGE, and 5-HMF were incubated at 40 degrees C for 40 days., Conventional and low-GDP fluids were incubated at various temperatures for up to, 3 weeks. Formaldehyde, acetaldehyde, glyoxal, methylglyoxal, 3-DG, 3,4-DGE, and 5-HMF were analyzed using high performance liquid chromatography. Results: Incubation of 100 mu mol/L 3,4-DGE resulted in the production of 36 mu mol/L 3-DG, 4 mu mol/L 5-HMF, and 40 mu mol/L unidentified substances. With the same incubation, 200 mu mol/L 3-DG was converted to 9 mu mol/L 3,4-DGE, 6 mu mol/L 5-HMF, and 14 mu mol/L unidentified substances. By contrast, 100 mu mol/L 5-HMF was uninfluenced by incubation. In a conventional PDF incubated at 60 degrees C for 1 day, the 3,4-DGE concentration increased from 14 to a maximum of 49 mu mol/L. When the fluids were returned to room temperature, the concentration decreased but did not reach original values until after 40 days. In a low GDP fluid, 3,4-DGE increased and decreased in the same manner as in the conventional fluid but reached a maximum of only 0.8 mu moL/L. Conclusions: Considerable amounts of 3,4-DGE maybe recruited by increases in temperature in conventional PDFs. Lowering the temperature will again reduce the concentration but much more time will be needed. Precursors for 3,4-DGE recruitment are most probably 3-DG and the enol 3-deoxyaldose-2-ene, but not 5-HMF. Considering the ease at which 3,4-DGE is recruited from its pool of precursors and the difficulty of getting rid of it again, one should be extremely careful with the temperatures conventional PDFs are exposed to.
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| 48. |
- Falahati, Sorour, 1971, et al.
(författare)
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Adaptive Modulation Systems for Predicted Wireless Channels
- 2004
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Ingår i: IEEE Transactions on Communications. - 0090-6778 .- 1558-0857. ; 52:2, s. 307-316
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Tidskriftsartikel (refereegranskat)abstract
- When adaptive modulation is used to counter short-term fading in mobile radio channels, signaling delays create problems with outdated channel state information. The use of channel power prediction will improve the performance of the link adaptation. It is then of interest to take the quality of these predictions into account explicitly when designing an adaptive modulation scheme. We study the optimum design of an adaptive modulation scheme based on uncoded M -quadrature amplitude modulation, assisted by channel prediction for the flat Rayleigh fading channel. The data rate, and in some variants the transmit power, are adapted to maximize the spectral efficiency, subject to average power and bit-error rate constraints. The key issues studied here are how a known prediction error variance will affect the optimized transmission properties, such as the signal-to-noise ratio (SNR) boundaries that determine when to apply different modulation rates, and to what extent it affects the spectral efficiency. This investigation is performed by analytical optimization of the link adaptation, using the statistical properties of a particular, but efficient, channel power predictor. Optimum solutions for the rate and transmit power are derived, based on the predicted SNR and the prediction error variance.
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| 49. |
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| 50. |
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