| 1. |
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Bioengineered Nanomaterials
- 2013
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- "This book focuses on the novel methodologies and strategies adopted during recent research and development of bioengineered nanomaterials for biomedical applications. It provides comprehensive and updated information on developments in this emerging area. The chapters discuss topics such as nanoemulsions as a vaccine adjuvant, bio-ceramic nanomaterials in medical applications, the potential of nanoparticles for the treatment of solid tumors and metastasis, natural and synthetic nanoporous membranes for cell encapsulation therapy, silver nanoparticles, nanotoxcity testing and bioapplications, inorganic nanoparticle materials for controlled release of drugs, and more"--Provided by publisher.Many varieties of new, complex diseases are constantly being discovered, which leaves scientists with little choice but to embrace innovative methods for controlling the invasion of life-threatening problems. The use of nanotechnology has given scientists an opportunity to create nanomaterials that could help medical professionals in diagnosing and treating problems quickly and effectively. Bioengineered Nanomaterials presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanom.
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| 2. |
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Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering
- 2013
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- "Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting and diagnostic imaging capabilities and are emerging as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. This reference work is one of the first to cover Nanotheragnostics which is the new edge of nanomedicine combining both diagnostic and therapeutic elements at nano level. This large multidisciplinary reference work is has four main parts: Biocompatible Nanomaterials; Nanomedicine: Drug Gene and Cell Delivery; Multi-functional Nanocarrier: Diagnosis, Imaging and Treatment; Tissue Engineering/Regenerative Medicine"--
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| 3. |
- Parlak, Onur, et al.
(författare)
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Template-Directed Hierarchical Self-Assembly of Graphene Based Hybrid Structure for Electrochemical Biosensing
- 2013
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Ingår i: Biosensors & bioelectronics. - : Elsevier. - 0956-5663 .- 1873-4235. ; 49, s. 53-62
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Tidskriftsartikel (refereegranskat)abstract
- A template-directed self-assembly approach, using functionalised graphene as a fundamental building block to obtain a hierarchically ordered graphene-enzyme-nanoparticle bioelectrode for electrochemical biosensing, is reported. An anionic surfactant was used to prepare a responsive, functional interface and direct the assembly on the surface of the graphene template. The surfactant molecules altered the electrostatic charges of graphene, thereby providing a convenient template-directed assembly approach to a free-standing planar sheet of sp(2) carbons. Cholesterol oxidase and cholesterol esterase were assembled on the surface of graphene by intermolecular attractive forces while gold nanoparticles are incorporated into the hetero-assembly to enhance the electro-bio-catalytic activity. Hydrogen peroxide and cholesterol were used as two representative analytes to demonstrate the electrochemical sensing performance of the graphene-based hybrid structure. The bioelectrode exhibited a linear response to H2O2 from 0.01 to 14 mM, with a detection limit of 25 nM (S/N=3). The amperometric response with cholesterol had a linear range from 0.05 to 0.35 mM, sensitivity of 3.14 mu A/mu M/cm(2) and a detection limit of 0.05 mu M. The apparent Michaelis-Menten constant (K-m(app)) was calculated to be 1.22 mM. This promising approach provides a novel methodology for template-directed bio-self-assembly over planar sp(2) carbons of a graphene sheet and furnishes the basis for fabrication of ultra-sensitive and efficient electrochemical biosensors.
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| 4. |
- Tiwari, Ashutosh, et al.
(författare)
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Bionanocomposite Matrices in Electrochemical Biosensors
- 2012
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Ingår i: Biomedical Materials and Diagnostic Devices. - USA : John Wiley & Sons. - 9781118030141 ; , s. 301-320
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration.
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| 5. |
- Tiwari, Atul, et al.
(författare)
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Biopolymers : An Indispensable Tool for Biotechnology
- 2012
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Ingår i: Biotechnology in Biopolymers. - United Kingdom : Smithers Rapra. - 9781847355423 ; , s. 1-16
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- This comprehensive book provides up-to-date information on the developments in the field of biopolymers. Close attention has been paid to include all the important aspects that are necessary to understand the field. The book introduces the reader with the progress in the field, followed by outlining its applications in different areas. Different methods and techniques of synthesis and characterization are detailed as individual chapters. Various mode and mechanism of degradation of materials will be discussed. There is a dedicated chapter on industrially available biopolymers and their applications and well as a chapter detailing the ongoing research, current trends and future challenges.
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| 6. |
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Advanced Bioelectronic Materials
- 2015
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- This book covers the recent advances in the development of bioelectronics systems and their potential application in future biomedical applications starting from system design to signal processing for physiological monitoring, to in situ biosensing.Advanced Bioelectronics Materialshas contributions from distinguished international scholars whose backgrounds mirror the multidisciplinary readership ranging from the biomedical sciences, biosensors and engineering communities with diverse backgrounds, interests and proficiency in academia and industry. The readers will benefit from the widespread coverage of the current literature, state-of-the-art overview of all facets of advanced bioelectronics materials ranging from real time monitoring, in situ diagnostics, in vivo imaging, image-guided therapeutics, biosensors, and translational biomedical devices and personalized monitoring.
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| 7. |
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Advanced Biomaterials and Biodevices
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Biomaterials are the fastest-growing emerging field of biodevices. Design and development of biomaterials play a significant role in the diagnosis, treatment, and prevention of diseases. Recently, a variety of scaffolds/carriers have been evaluated for tissue regeneration, drug delivery, sensing and imaging. Liposomes and microspheres have been developed for sustained delivery. Several anti-cancer drugs have been successfully formulated using biomaterial. The targeting of drugs to certain physiological sites has emerged as a promising tool in the treatment with improved drug bioavailability and reduction of dosing frequency. Biodevices-based targeting of drugs may improve the therapeutic success by limiting the adverse drug effects and resulting in more patient compliance and attaining a higher adherence level. Advanced biodevices hold merit as a drug carrier with high carrier capacity, feasibility of incorporation of both hydrophilic and hydrophobic substances, high stability, as well as the feasibility of variable courses. Biodevices for diagnosis of diseases by improving the sensitivity and selectivity on the biomaterials platform is the most latest R & D focus especially in the field of treatment by the prognosis and detection of disease in the early stage. This groundbreaking book is devoted to all of the emerging areas of biomaterials and biodevices including therapeutic agents, molecular targeting and diagnostic imaging capabilities. The senior contributors write on the following topics:Frontiers for bulk nanostructured metalsStimuli-responsive materials used as medical devicesRecent advances with liposomes as drug carriersFabrication, Properties of nanoshells with controllable surface chargeAdvanced healthcare materials: ChitosanAnticipating behaviour of advanced material in healthcareLabel free biochipsPolymer MEMS sensorsAssembly of polymers/metal nanoparticlesCombination of molecular imprinting and nanotechnologyEfficiency of biosensors as new generation of analytical approachesState-of-the-art of biosensors in healthcare
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| 8. |
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Advanced Carbon Materials and Technology
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The expansion of carbon materials is multidisciplinary and is related to physics, chemistry, biology, applied sciences and engineering. The research on carbon materials has mostly focused on aspects of fundamental physics as they unique electrical, thermal and mechanical properties applicable for the range of applications.
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| 9. |
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Advanced Energy Materials
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- An essential resource for scientists designing new energy materials for the vast landscape of solar energy conversion as well as materials processing and characterizatio.Based on the new and fundamental research on novel energy materials with tailor-made photonic properties, the role of materials engineering has been to provide much needed support in the development of photovoltaic devices. Advanced Energy Materials offers a unique, state-of-the-art look at the new world of novel energy materials science, shedding light on the subject's vast multi-disciplinary approach.The book focuses particularly on photovoltaics, efficient light sources, fuel cells, energy-saving technologies, energy storage technologies, nanostructured materials as well as innovating materials and techniques for future nanoscale electronics. Pathways to future development are also discussed.Critical, cutting-edge subjects are addressed, including:Non-imaging focusing heliostat; state-of-the-art of nanostructuresMetal oxide semiconductors and their nanocompositesSuperionic solids; polymer nanocomposites; solid electrolytes; advanced electronicsElectronic and optical properties of lead sulfideHigh-electron mobility transistors and light-emitting diodesAnti-ferroelectric liquid crystals; PEEK membrane for fuel cellsAdvanced phosphors for energy-efficient lightingMolecular computation photovoltaics and photocatalystsPhotovoltaic device technology and non-conventional energy applicationsReadershipThe book is written for a large and broad readership including researchers and university graduate students from diverse backgrounds such as chemistry, materials science, physics, and engineering working in the fields of nanotechnology, photovoltaic device technology, and non-conventional energy.
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| 10. |
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Advanced Healthcare Materials
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Advanced materials are attracting strong interest in the fundamental as well as applied sciences and are being extensively explored for their potential usage in a range of healthcare technological and biological applications.Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices. The book highlights the key features which enable engineers to design stimuli-responsive smart nanoparticles, novel biomaterials, nano/micro-devices for diagnosis, therapy (theranostics).The leading contributor researchers cover the following topics: State-of-the-art of biomaterials for human healthMicro- and nanoparticles and their application in biosensorsThe role of immunoassaysStimuli-responsive smart nanoparticlesDiagnosis and treatment of cancerAdvanced materials for biomedical application and drug deliveryNanoparticles for diagnosis and/or treatment of Alzheimers diseaseHierarchical modelling of elastic behavior of human dental tissueBiodegradable porous hydrogelsHydrogels in tissue engineering, drug delivery and wound careModified natural zeolitesSupramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxanePolyhydroxyalkanoate-based biomaterialsBiomimetic molecularly imprinted polymersThe book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications.
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| 11. |
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Advanced Materials for Agriculture, Food and Environmental Safety
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The levels of toxic and microbial contamination in the food and environment are influenced by harvesting or slaughtering technologies and by the processes applied during food manufacture. With current cultivation methods, it is impossible to guarantee the absence of pesticides and pathogenic microorganisms in raw foods, both of plant and animal origin. Widespread and increasing incidence of foodborne diseases and the resulting social and economic impact on the world population have brought food and environmental safety to the forefront of ecological safety and public health concerns. The emerging field of advanced materials based on functional architectures offers potential solutions to some of the key performance challenges along with the improved sensitivity, longevity, stability, miniaturization and ruggedness, while reducing complexity and production cost. The overall purpose of this book is to generate new solutions to the technical challenges in easy and rapid detections of food toxicants, microorganisms and environmental pollutants. The book focuses on the role of advanced materials in the food, water and environmental applications. The monitoring of harmful organisms and toxicants in water, food and beverages is mainly discussed in the respective chapters. The senior contributors write on the following topics:Layered double hydroxides and environmentCorrosion resistance of aluminium alloys of silanesNew generation material for the removal of arsenic from waterPrediction and optimization of heavy clay products qualityEnhancement of physical and mechanical properties of fiberEnvironment friendly acrylates laticesNanoparticles for trace analysis of toxinsRecent development on gold nanomaterial as catalyst Nanosized metal oxide based adsorbents for heavy metal removalPhytosynthesized transition metal nanoparticles- novel functional agents for textilesKinetics and equilibrium modelingMagnetic nanoparticles for heavy metal removalPotential applications of nanoparticles as antipathogensGas barrier properties of biopolymer based nanocomposites: Application in food packingApplication of zero-valent iron nanoparticles for environmental clean upEnvironmental application of novel TiO2 nanoparticles
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| 12. |
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Advanced Sensor and Detection Materials
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The development of sensors at macroscopic or nanometric scales in solid, liquid, or gas phases, contact or noncontact configurations, has driven the research of sensor & detection materials and technology into high gear. The emphasis on detection techniques requires the use of spin crossover organic, inorganic and composite materials and methods that could be unique for sensors fabrication. The influence of length, composition and conformation structure of materials on their properties and the possibilities to adjust sensing properties by doping or adding the side-groups are the starting point of multifarious sensing. The role of inter-molecular interactions, polymer and ordered phases formation, as well as the behavior under pressure, magnetic and electric fields are also important facts for processing of ultra-sensing materials. Advanced Sensor and Detection Materials highlights the key features that aid the design of new sensor and detection materials for a multitude of sensor and detection devices. The senior contributors write on the follow topics:Construction of nanostructuresThe role of the shape in the design of new nanoparticlesAdvances in sensors’ nanotechnologyMolecularly imprinted polymer for enantioselective sensing devicesFerrites for high frequency applicationsMesoporous Silica: Making “Sense” of SensorsPorous TiO2-Au/Ag materialsFerroelectronic glass-ceramicsNASICON: Synthesis, structure and electrical characterisationHeavy clay products qualityIonic liquidsDendrimers and hyperbranched polymersTheoretical investigation of superconducting state parametersMicroscopic polarization and thermal conductivity of binary Wurtzite nitridesExperiments techniques and theoretical background to study materialsThe book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on advanced materials for sensor and detection technology and applications.
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| 13. |
- Ali Kamyabi, Mohammad, et al.
(författare)
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A high-performance glucose biosensor using covalently immobilised glucose oxidase on a poly(2,6-diaminopyridine)/carbon nanotube electrode
- 2013
-
Ingår i: Talanta. - : Elsevier. - 0039-9140 .- 1873-3573. ; 116, s. 801-808
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Tidskriftsartikel (refereegranskat)abstract
- A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Cyclic voltammetry was used for both the electrochemical synthesis of poly-(2,6-DP) on the surface of a MWNT-modified GC electrode, and characterisation of the polymers deposited on the GC electrode. The synergistic effect of the high active surface area of both the conducting polymer, i.e., poly-(2,6-DP) and MWNT gave rise to a remarkable improvement in the electrocatalytic properties of the biosensor. The transfer coefficient (alpha), heterogeneous electron transfer rate constant and Michaelis-Menten constant were calculated to be 0.6, 4 s(-1) and 0.20 mM at pH 7.4, respectively. The GOx/poly(2,6-DP)/MWNT/GC bioelectrode exhibited two linear responses to glucose in the concentration ranging from 0.42 mu M to 8.0 mM with a correlation coefficient of 0.95, sensitivity of 52.0 mu AmM-1 cm(-2), repeatability of 1.6% and long-term stability, which could make it a promising bioelectrode for precise detection of glucose in the biological samples. (C) 2013 Elsevier B.V. All rights reserved.
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| 14. |
- Ali Kamyabi, Mohammad, et al.
(författare)
-
Correction: A high-performance glucose biosensor using covalently immobilised glucose oxidase on a poly(2,6-diaminopyridine)/carbon nanotube electrode (vol 116, pg 801, 2013)
- 2016
-
Ingår i: Talanta. - : ELSEVIER SCIENCE BV. - 0039-9140 .- 1873-3573. ; 153, s. 414-415
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Tidskriftsartikel (refereegranskat)abstract
- A highly-sensitive glucose biosensor amenable to ultraminiaturisation was fabricated by immobilization of glucose oxidase (wGOX), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWCNT/GCE). Cyclic voltammetry was used for both the electrochemical synthesis of poly-(2,6-DP) on the surface of a MWCNT-modified GC electrode, and characterization of the polymers deposited on the GC electrode. The synergistic effect of the high active surface area of both the conducting-polymer, i.e., poly-(2,6-DP) and MWCNT gave rise to a remarkable improvement in the electrocatalytic properties of the biosensor. The transfer coefficient (alpha), heterogeneous electron transfer rate constant and Michaelis-Menten constant were calculated to be 0.6, 4 s-1 and 0.22 mM at pH 7.4, respectively. The GOx/poly(2,6-DP)/MWCNT/GC bioelectrode exhibited two linear responses to glucose in the concentration ranging from 0.42 mu M to 8.0 mM with a correlation coefficient of 0.95, sensitivity of 52.0 mu AmM-1 cm-2, repeatability of 1.6% and long-term stability, which could make it a promising bioelectrode for precise detection of glucose in the biological samples. (C) 2016 Elsevier B.V. All rights reserved.
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| 15. |
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| 16. |
- Ashaduzzaman, Md., et al.
(författare)
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On/off-switchable LSPR nano-immunoassay for troponin-T
- 2017
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Regeneration of immunosensors is a longstanding challenge. We have developed a re-usable troponin-T (TnT) immunoassay based on localised surface plasmon resonance (LSPR) at gold nanorods (GNR). Thermosensitive poly(N-isopropylacrylamide) (PNIPAAM) was functionalised with anti-TnT to control the affinity interaction with TnT. The LSPR was extremely sensitive to the dielectric constant of the surrounding medium as modulated by antigen binding after 20 min incubation at 37 degrees C. Computational modelling incorporating molecular docking, molecular dynamics and free energy calculations was used to elucidate the interactions between the various subsystems namely, IgG-antibody (c. f., anti-TnT), PNIPAAM and/or TnT. This study demonstrates a remarkable temperature dependent immuno-interaction due to changes in the PNIPAAM secondary structures, i.e., globular and coil, at above or below the lower critical solution temperature (LCST). A series of concentrations of TnT were measured by correlating the lambda(LSPR) shift with relative changes in extinction intensity at the distinct plasmonic maximum (i. e., 832 nm). The magnitude of the red shift in lambda(LSPR) was nearly linear with increasing concentration of TnT, over the range 7.6 x 10(-15) to 9.1 x 10(-4) g/mL. The LSPR based nano-immunoassay could be simply regenerated by switching the polymer conformation and creating a gradient of microenvironments between the two states with a modest change in temperature.
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| 17. |
- Ashaduzzaman, M., et al.
(författare)
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Studies on an on/off-switchable immunosensor for troponin T
- 2015
-
Ingår i: Biosensors & bioelectronics. - : Elsevier BV. - 0956-5663 .- 1873-4235. ; 73
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Tidskriftsartikel (refereegranskat)abstract
- Regeneration is a key goal in the design of immunosensors. In this study, we report the temperature-regulated interaction of N-isopropylacrylamide (PNIPAAm) functionalised cardiac troponin T (cTnT) with anti-cTnT. Covalently bonded PNIPAAm on an anti-cTnT bioelectrode showed on/off-switchability, regeneration capacity and temperature triggered sensitivity for cTnT. Above the lower critical solution temperature (LCST), PNIPAAm provides a liphophilic microenvironment with specific volume reduction at the bioelectrode surface, making available binding space for cTnT, and facilitating analyte recognition. Computational studies provide details about the structural changes occurring at the electrode above and below the LCST. Furthermore, free energies associated with the binding of cTnT with PNIPAAm at 25 (δGcoil=-6.0Kcal/mole) and 37°C (δGglobular=-41.0kcal/mole) were calculated to elucidate the interaction and stability of the antigen-antibody complex. The responsiveness of such assemblies opens the way for miniaturised, smart immuno-technologies with 'built-in' programmable interactions of antigen-antibody upon receiving stimuli.
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| 18. |
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Biomedical materials and diagnostic devices
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- "The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration"--Provided by publisher.
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| 19. |
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Biosensors Nanotechnology
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- A new emerging field that combines nanoscale materials and biosensor technology is receiving increased attention. Nanostructures have been used to achieve direct wiring of biosensing elements to electrode surfaces, to promote bio-reactions, to impose nanobarcodes on biomaterials, and to amplify the signal from bio-recognition events. Nanomaterials based biosensors have found wide spread applications in the environmental and medical applications for their sensitivity, specificity, rapidity, simplicity, and cost-effectiveness. In the same pursuit, Biosensors Nanotechnology provides detailed review chapters on a range of nanostructures such as nanoparticles, nanowires, nanotubes, nanoribbons, nanorods, nanobelts and nanosheets in the construction of biosensors with set applications of biosensors nanotechnology for biological and chemical analyses, food safety industry, biomedical diagnostics, clinical detection, and environmental monitoring.
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| 20. |
- Chey, Chan Oeurn, et al.
(författare)
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Impact of nanotoxicology towards technologists to end users
- 2013
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Ingår i: Advanced Materials Letters. - Allahabad, Uttar Pradesh , India : Vinova Bhave Research Institute. - 0976-3961 .- 0976-397X. ; 4:8, s. 591-597
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Tidskriftsartikel (refereegranskat)abstract
- The length scale for nanomaterial is small enough to be invisible and presume innocence for the initial avoidance of the toxicity issues. Again it was beyond the understanding of the time frame when nanotechnology just blooms that a length scale itself might be an important toxic parameter apart from its materialistic properties. We present this report to address the fundamental issues and questions related to the nanotoxicity issues from laboratory to the land of applications. We emphasize about the basic nanoscale materials that are regularly being used by the scientific community and the nanotechnology based materials that has already in the market or will come soon.
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| 21. |
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| 22. |
- Gurrani, Swapnil, et al.
(författare)
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Biomass Hydrolyzing Enzymes
- 2024
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Ingår i: <em>Biomass Hydrolyzing Enzymes: Basics, Advancements, and Applications</em>. - : CRC Press. ; , s. 3-13
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Lignocellulosic biomass is the most abundant, ubiquitous polymer on Earth available to benefit mankind. Biomass biorefinery has taken center stage in the world’s economy and is becoming diverse with time. With biorefinery, cascades of products can be obtained from biomass rather than a single product. It is a complex structure that consists of three polymers as cellulose, hemicellulose and lignin, linked to each other in a compact intricate manner making it difficult to be attacked by microorganisms. Still, many microorganisms have evolved strategies to consume this abundant material as an energy source. Degradation of lignocellulosic biomass is not only a survival strategy for these microbes, but its destruction also plays a pivotal role in carbon recycling of Earth through the fixation of photosynthetically fixed carbon present in plant biomass. Mankind has explored the capacity of microorganisms to produce polymer-degrading enzymes to deconstruct its basic components. Biomass-degrading enzymes have attracted researchers worldwide as this is the most sustainable way to obtain fermentable sugars from this most abundant biomass. Synergism among enzymes as well as their various components are presented along with challenges of biomass hydrolysis and probable solutions. © 2024 selection and editorial matter, Reeta Rani Singhania, Anil Kumar Patel, Héctor A. Ruiz, Ashok Pandey; individual chapters, the contributors.
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| 23. |
- Imani, Roghayeh, et al.
(författare)
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Band edge engineering of TiO2@DNA nanohybrids and implications for capacitive energy storage devices.
- 2015
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Ingår i: Nanoscale. - : RSC Publishing. - 2040-3364 .- 2040-3372. ; 7:23, s. 10438-10448
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Tidskriftsartikel (refereegranskat)abstract
- Novel mesoporous TiO2@DNA nanohybrid electrodes, combining covalently encoded DNA with mesoporous TiO2 microbeads using dopamine as linker, were prepared and characterised for application in supercapacitors. Detailed information about donor density, charge transfer resistance and chemical capacitance, which have important role in the performance of an electrochemical device, were studied by electrochemical methods. The results indicated the improvement of electrochemical performance of TiO2 nanohybrid electrode by DNA surface functionalisation. A supercapacitor was constructed from TiO2@DNA nanohybrids with PBS as electrolyte. From the supercapacitor experiment, it was found that the addition of DNA played an important role in improving the specific capacitance (Cs) of the TiO2 supercapacitor. The highest Cs value of 8 F/g was observed for TiO2@DNA nanohybrids. The nanohybrid electrodes were shown to be stable over long-term cycling, retaining 95% of their initial specific capacitance after 1500 cycles.
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| 24. |
- Imani, Roghayeh, et al.
(författare)
-
Band edge engineering of TiO2@DNA nanohybrids and implications for capacitive energy storage devices
- 2015
-
Ingår i: Nanoscale. - : Royal Society of Chemistry (RSC). - 2040-3364 .- 2040-3372. ; 7:23, s. 10438-10448
-
Tidskriftsartikel (refereegranskat)abstract
- Novel mesoporous TiO2@DNA nanohybrid electrodes, combining covalently encoded DNA with mesoporous TiO2 microbeads using dopamine as a linker, were prepared and characterised for application in supercapacitors. Detailed information about donor density, charge transfer resistance and chemical capacitance, which have an important role in the performance of an electrochemical device, were studied by electrochemical methods. The results indicated the improvement of electrochemical performance of the TiO2 nanohybrid electrode by DNA surface functionalisation. A supercapacitor was constructed from TiO2@DNA nanohybrids with PBS as the electrolyte. From the supercapacitor experiment, it was found that the addition of DNA played an important role in improving the specific capacitance (C-s) of the TiO2 supercapacitor. The highest Cs value of 8 F g(-1) was observed for TiO2@DNA nanohybrids. The nanohybrid electrodes were shown to be stable over long-term cycling, retaining 95% of their initial specific capacitance after 1500 cycles.
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| 25. |
- Imani, Roghayeh, et al.
(författare)
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Electrochemical detection of DNA damage through visible-light-induced ROS using mesoporous TiO2 microbeads
- 2014
-
Ingår i: Electrochemistry communications. - Philadelphia, PA, United States : Elsevier. - 1388-2481 .- 1873-1902. ; 40, s. 84-87
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Tidskriftsartikel (refereegranskat)abstract
- Rapid detection of DNA damage could serve as a basis for genotoxicity studies of new bio-nanoconjugations. A novel TiO2 bio-nanoconjugation, consisting of mesoporous TiO2 microbeads, dopamine (DA) and ss-DNA, was constructed on fluorine-doped tin oxide-coated glass (FTO) and used for the detection of DNA damage in the photocatalytic reaction of TiO2 under visible light. Stable mesoporous TiO2 microbeads films were coated on FTO by the doctor-blade method; dopamine with oxygen containing ligands, was tightly coupled to the titanium surface prepaired under phase coordination. Specific single-strands of DNA were electronically linked to TiO2 by using a dopamine bridge. DNA damage, caused by reactive oxygen species (ROS) that were photogenerated through the photocatalytic reaction, was detected with square wave voltammetry (SWV) by recording the catalytic oxidation current of [Ru(NH3)6]3 +, an intercalated electroactive probe. The ability of antioxidant to protect DNA against damage in the photocatalytic reaction was also tested.
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| 26. |
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Integrated Biomaterials for Biomedical Technology
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications.
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| 27. |
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Intelligent nanomaterials
- 2016. - 2
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- Overall, this book presents a detailed and comprehensive overview of the state-of-the-art development of different nanoscale intelligent materials for advanced applications. Apart from fundamental aspects of fabrication and characterization of nanomaterials, it also covers key advanced principles involved in utilization of functionalities of these nanomaterials in appropriate forms. It is very important to develop and understand the cutting-edge principles of how to utilize nanoscale intelligent features in the desired fashion. These unique nanoscopic properties can either be accessed when the nanomaterials are prepared in the appropriate form, e.g., composites, or in integrated nanodevice form for direct use as electronic sensing devices. In both cases, the nanostructure has to be appropriately prepared, carefully handled, and properly integrated into the desired application in order to efficiently access its intelligent features. These aspects are reviewed in detail in three themed sections with relevant chapters: Nanomaterials, Fabrication and Biomedical Applications; Nanomaterials for Energy, Electronics, and Biosensing; Smart Nanocomposites, Fabrication, and Applications.
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| 28. |
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Intelligent Nanomaterials : processes, properties, and applications
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The last three decades have seen extraordinary advances in the generation of new materials based on both fundamental elements and composites, driven by advances in synthetic chemistry and often drawing inspiration from nature. The concept of an intelligent material envisions additional functionality built into the molecular structure, such that a desirable response occurs under defined conditions.Divided into 4 parts: Inorganic Materials; Organic Materials; Composite Materials; and Biomaterials, the 22 chapters cover the latest research and developments in the processing, properties, and applications of intelligent nanomaterials. Included are molecular device materials, biomimetic materials, hybrid-type functionalized polymers-composite materials, information-and energy-transfer materials, as well as environmentally friendly materials.
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| 29. |
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Intelligent Nanomaterials, 2nd Edition.
- 2016
-
Samlingsverk (redaktörskap) (refereegranskat)abstract
- Overall, this book presents a detailed and comprehensive overview of the state-of-the-art development of different nanoscale intelligent materials for advanced applications. Apart from fundamental aspects of fabrication and characterization of nanomaterials, it also covers key advanced principles involved in utilization of functionalities of these nanomaterials in appropriate forms. It is very important to develop and understand the cutting-edge principles of how to utilize nanoscale intelligent features in the desired fashion. These unique nanoscopic properties can either be accessed when the nanomaterials are prepared in the appropriate form, e.g., composites, or in integrated nanodevice form for direct use as electronic sensing devices. In both cases, the nanostructure has to be appropriately prepared, carefully handled, and properly integrated into the desired application in order to efficiently access its intelligent features. These aspects are reviewed in detail in three themed sections with relevant chapters: Nanomaterials, Fabrication and Biomedical Applications; Nanomaterials for Energy, Electronics, and Biosensing; Smart Nanocomposites, Fabrication, and Applications.
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| 30. |
- Karimian, Najmeh, et al.
(författare)
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A potential-gated molecularly imprinted smart electrode for nicotinamide analysis
- 2015
-
Ingår i: RSC Advances. - : Royal Society of Chemistry. - 2046-2069. ; 5:44, s. 35089-35096
-
Tidskriftsartikel (refereegranskat)abstract
- Triggered surface responsiveness paves the way for smart sensor technologies that not only have tunable retention, but also provide sensing through a built-in programming of electrode material. In this study, we report a potential-gated electrochemical sensor for determination of nicotinamide (NAM) based on a molecularly imprinted overoxidised polypyrrole electrode. The sensitive layer was prepared by electropolymerisation of pyrrole on a glassy carbon electrode in the presence of NAM as a template molecule, followed by alkali extraction. Electrochemical methods were used to monitor the processes of electropolymerisation, template removal and binding in the presence of a [Fe(CN)(6)](3-)/[Fe(CN)(6)](4-) redox couple as an electrochemical probe. Several factors affecting the performance of the MIP-modified electrode were investigated and optimized. The peak current of the ferro/ferricyanide couple decreased linearly with successive addition of NAM in the concentration range 0.9 x 10(-6) to 9.9 x 10(-3) M with a detection limit of 1.7 x 10(-7) M (S/N = 3). The molecularly-imprinted polymer (MIP) electrode had excellent recognition capability for NAM compared to structurally related molecules. Moreover, the reproducibility and repeatability of the NAM-imprinted electrode were all found to be satisfactory. The results from sample analysis confirmed the applicability of the NAM-imprinted electrode to reusable quantitative analysis in commercial pharmaceutical samples.
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| 31. |
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| 32. |
- Karimian, Najmeh, et al.
(författare)
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An ultrasensitive molecularly-imprinted human cardiac troponin sensor
- 2013
-
Ingår i: Biosensors & bioelectronics. - : Elsevier. - 0956-5663 .- 1873-4235. ; 50, s. 492-498
-
Tidskriftsartikel (refereegranskat)abstract
- Cardiac troponin T (TnT) is a highly sensitive cardiac biomarker for myocardial infarction. In this study, the fabrication and characterisation of a novel sensor for human TnT based on a molecularly-imprinted electrosynthesised polymer is reported. A TnT sensitive layer was prepared by electropolymerisation of o-phenylenediamine (o-PD) on a gold electrode in the presence of TnT as a template. To develop the molecularly imprinted polymer (MIP), the template molecules were removed from the modified electrode surface by washing with alkaline ethanol. Electrochemical methods were used to monitor the processes of electropolymerisation, template removal and binding. The imprinted layer was characterised by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and atomic force microscopy (AFM). The incubation of the MIP-modified electrode with respect to TnT concentration resulted in a suppression of the ferro/ferricyanide redox process. Experimental conditions were optimised and a linear relationship was observed between the peak current of [Fe(CN)(6)](3-)/[Fe (CN)(6)](4-) and the concentration of TnT in buffer over the range 0.009-0.8 ng/mL, with a detection limit of 9 pg/mL. The TnT MIP sensor was shown to have a high affinity to TnT in comparison with nonimprinted polymer (NIP) electrodes in both buffer and blood serum.
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| 33. |
- Karimian, Najmeh, et al.
(författare)
-
Electrochemical evaluation of troponin T imprinted polymer receptor
- 2014
-
Ingår i: Biosensors & bioelectronics. - USA : Elsevier. - 0956-5663 .- 1873-4235. ; 59, s. 160-165
-
Tidskriftsartikel (refereegranskat)abstract
- The selective detection and quantification of macromolecular targets is a fundamental biological mechanism in nature. Molecularly imprinted polymers (MIPs) have been identified as one of the most promising synthetic alternatives to bioreceptors. However, expanding this methodology towards selective recognition of bulky templates such as proteins appears to be extremely challenging due to problems associated with removal of the template from the polymeric network. In this study, polymer imprinted with troponin T (TnT) was assessed using electrochemical methods and the influence of various extraction methods, including conventional immersion extraction, thermal annealing and ultrasonic-assisted extraction, on the binding characteristics of the troponin-to-imprinted polymer receptor was elucidated. Cyclic voltammetric deposition of o-phenylenediamine (o-PD) film in the presence of TnT as a template was performed in acetate buffer (0.5 M, pH 5.2) on a gold substrate. Solvent extraction of the target molecule was optimised and followed by subsequent washing with water. The electrochemistry of a ferro/ferricyanide probe was used to characterise the TnT MIP receptor film. The incubation of the TnT MIP receptor-modified electrode with respect to TnT concentration resulted in a suppression of the ferro/ferricyanide redox current. The dissociation constant (KD) was calculated using a two-site model of template affinity for the TnT MIP receptor. The synthetic TnT MIP receptor had high affinity for TnT with a KD of 2.3×10−13 M.
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| 34. |
- Karimian, N, et al.
(författare)
-
On/off-switchable electrochemical sensor for folicacid based on molecularly imprinted technology.
- 2013
-
Ingår i: Electrochemistry communications. - : Elsevier BV. - 1388-2481 .- 1873-1902. ; 36, s. 92-95
-
Tidskriftsartikel (refereegranskat)abstract
- The combination of smart polymers with molecular imprinting offers a powerful tool to design more effective sensors and medical devices. In this study, a temperature sensitive amine-terminated poly(N-isopropylacrylamide) block with (N,N'-methylenebisacrylamide) cross-linker along with o-phenylenediamine was electropolymerised on a gold electrode in the presence of folic acid (FA) as template to produce an on/off-switchable molecularly imprinted polymer (MIP) affinity sensor for folic acid. Differential pulse voltammetry and cyclic voltammetry were used to characterise the FA-imprinted layer. Incubation of the MIP-modified electrode with FA resulted in a suppression of the ferro/ferricyanide redox process. The highest sensitivity of this temperature gated on/off-switchable folic acid sensor was achieved at 22 °C. Such switchable affinity materials offer considerable potential for the design of highly selective and controllable biosensors and immunoassays.
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| 35. |
- Karimiana, Naymeh, et al.
(författare)
-
On/off-switchable folic acid sensor using molecularly imprinted smart polymer electrode
- 2014
-
Ingår i: 24<sup>th</sup>Anniversary World Congress on Biosensors – Biosensors 2014. - : Elsevier.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Recently, much attention has been focused on the development of controlled switchable surfaces, also known as “smart surfaces”, which switch their physicochemical properties in response to external stimuli [1]. Switching of a surface based on temperature can be realised using thermo-sensitive polymers, which undergo a phase transition at the lower critical solution temperature (LCST), where their behavior switches between hydrophobic and hydrophilic [2]. LCST modulation can be achieved by copolymerisation with other monomers in order to produce a LCST close to physiological temperature. Thus, it could be useful in controllable, temperature-responsive bio-switches for biomedical and biotechnology applications [3]. The combination of smart polymers with molecular imprinting offers a powerful tool to design more effective sensors and medical devices. In this study, a temperature sensitive amine-terminated poly(N-isopropylacrylamide) block with (N,N'-methylenebisacrylamide) cross-linker along with o-phenylenediamine was electropolymerised on a gold electrode in the presence of folic acid (FA) as template to produce an on/off-switchable molecularly imprinted polymer (MIP) affinity sensor for folic acid. Differential pulse voltammetry and cyclic voltammetry were used to characterise the FA-imprinted layer. Incubation of the MIP-modified electrode with FA resulted in a suppression of the ferro/ferricyanide redox process. The highest sensitivity of this temperature gated on/off-switchable folic acid sensor was achieved at 22 ºC. Such switchable affinity materials offer considerable potential for the design of highly selective and controllable biosensors and immunoassays.
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| 36. |
- Kashefi-Kheyrabadi, Leila, et al.
(författare)
-
Ultrasensitive detection of human liver hepatocellular carcinoma (HepG2) cells using a label-free aptasensor
- 2014
-
Ingår i: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 86:10, s. 4956-4960
-
Tidskriftsartikel (refereegranskat)abstract
- Liver cancer is one of the most common cancers in the world and has no effective cure, especially in later stages. The development of a tangible protocol for early diagnosis of this disease remains a major challenge. In the present manuscript, an aptamer-based, label-free electrochemical biosensor for the sensitive detection of HepG2, a hepatocellular carcinoma cell line, is described. The target cells are captured in a sandwich architecture using TLS11a aptamer covalently attached to a gold surface and a secondary TLS11a aptamer. The application of TLS11a aptamer as a recognition layer resulted in a sensor with high affinity for HepG2 cancer cells in comparison with control cancer cells of human prostate, breast and colon tumours. The aptasensor delivered a wide linear dynamic range over 1 × 102 – 1 × 106 cell/mL, with a detection limit of 2 cell/mL. This protocol provides a precise method for sensitive detection of liver cancer with significant advantages in terms of simplicity, low cost, and stability.
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| 37. |
- Kumari, Poonam, et al.
(författare)
-
Study of Ca doping on A- site on the structural and physical properties of BLTMNZ ceramics
- 2014
-
Ingår i: Advanced Materials Letters. - : Vinova Bhave Research Institute. - 0976-3961 .- 0976-397X. ; 5:5, s. 255-259
-
Tidskriftsartikel (refereegranskat)abstract
- The ferroelectric Ca doped (Ba0.9575La0.04X0.0025) (Ti0.815Mn0.0025Nb0.0025Zr0.18)0.99O3 was prepared by a high-temperature solid state reaction technique. For the understanding of the electrical and dielectric property, the relation between the crystal structures, electrical transition and ferroelectric transitions with increasing temperature (–160 to 35°C) have been analyzed. X-ray diffraction analysis of the powders suggests the formation of a single-phase material with monoclinic structure. Capacitance and tanδ of the specimens were measured in the temperature range from -160 to 35°Cat frequencies 1 kHz – 1 MHz. Detailed studies of dielectric and electrical properties indicate that the Curie temperature shifted to higher temperature with the increase in frequency. Moreover, the dielectric maxima dropped down rapidly initially and the dielectric peaks became extremely broad. The AC conductivity increases with increase in frequency. The low value of activation energy obtained for the ceramic samples could be attributed to the influence of electronic contribution to the conductivity.
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| 38. |
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| 39. |
- Li, Songjun, et al.
(författare)
-
‘On/off’-switchable catalysis by a smart enzyme-like imprinted polymer
- 2011
-
Ingår i: Journal of Catalysis. - : Elsevier. - 0021-9517 .- 1090-2694. ; 278:2, s. 173-180
-
Tidskriftsartikel (refereegranskat)abstract
- ‘On/off’-switchable catalysis by a smart enzyme-like imprinted polymer is reported. This unique imprinted polymer was composed of poly(N-isopropylacrylamide)-containing p-nitrophenyl phosphate-imprinted networks that exhibited temperature-dependent hydrophilicity/hydrophobicity. At a relatively low temperature (such as 20 °C), this polymer was capable of vigorous catalysis for the hydrolysis of p-nitrophenyl acetate due to its hydrophilic networks, which enabled access to the imprinted framework. On the contrary, at higher temperatures (such as 40 °C), this polymer demonstrated poor catalysis resulting from its dramatically increased hydrophobicity, which inhibited access to the imprinted sites. Unlike previously reported imprinted polymers which lack adjustable networks, this novel imprinted polymer employed thermosensitive poly(N-isopropylacrylamide) networks, thus enabling the switchable catalysis.
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| 40. |
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| 41. |
- Mirzapoor, Aboulfazl, et al.
(författare)
-
Electrochemical detection of DNA mismatches using a branch-shaped hierarchical SWNT-DNA nano-hybrid bioelectrode
- 2019
-
Ingår i: Materials science & engineering. C, biomimetic materials, sensors and systems. - : ELSEVIER. - 0928-4931 .- 1873-0191. ; 104
-
Tidskriftsartikel (refereegranskat)abstract
- Common approaches for DNA mutation detection are high cost and have difficult or complex procedure. We propose a fast quantitative method for recognition of DNA mutation based on SWNT/DNA self-assembled nanostructure. Covalent SWNT/DNA hybrid nanostructures are widely used in the fabrication of electrochemical biosensors. Interfacing carbon nanotubes with DNA in particular, is used as a detection method for the analysis of genetic disorders or the detection of mismatches in DNA hybridisation. We have designed a self-assembled, branch-shaped hybrid nanostructure by hybridisation of two sticky oligos that are attached to the ends of SWNTs via a linker oligo. These hybrid nanostructures showed a good conductivity that was greater than free SWNTs. Impedance spectroscopy studies illustrated that the conductivity of these hybrid nanostructures depended on the conformation and structure of the hybridised DNA. We demonstrated that the strategy of using SWNT/DNA self-assembled hybrid nanostructure fabrication yields sensitive and selective tools to discriminate mismatches in DNA. Cyclic voltammetry (CV) and impedance spectroscopy clearly revealed that the conductivity of the branch-shaped and hierarchical hybridised SWNT/DNA nanostructure is higher when matched, than when mismatched in a 1 and 1 hybridised SWNT/DNA nanostructure. Rapid biosensing of match and mismatch nanostructure based on carbon printed electrode showed similar results which can be used for rapid and fast detection of DNA mismatch.
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| 42. |
- Mishra, Ajay Kumar, et al.
(författare)
-
Polymers/Composites Based Intelligent Transducers
- 2012
-
Ingår i: Intelligent Nanomaterials. - USA : John Wiley & Sons. - 9780470938799 ; , s. 571-584
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The last three decades have seen extraordinary advances in the generation of new materials based on both fundamental elements and composites, driven by advances in synthetic chemistry and often drawing inspiration from nature. The concept of an intelligent material envisions additional functionality built into the molecular structure, such that a desirable response occurs under defined conditions.Divided into 4 parts: Inorganic Materials; Organic Materials; Composite Materials; and Biomaterials, the 22 chapters cover the latest research and developments in the processing, properties, and applications of intelligent nanomaterials. Included are molecular device materials, biomimetic materials, hybrid-type functionalized polymers-composite materials, information-and energy-transfer materials, as well as environmentally friendly materials.
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| 43. |
- Mishra, Abhishek, et al.
(författare)
-
Sustainable chemical preventive models in COVID-19 : Understanding, innovation, adaptations, and impact
- 2021
-
Ingår i: Journal of the Indian Chemical Society. - : Elsevier BV. - 0019-4522. ; 98:10
-
Tidskriftsartikel (refereegranskat)abstract
- COVID-19 is considered as a major public health problem caused by the SARS CoV-2. This Viral infection is known to induce worldwide pandemic in short period of time. Emerging evidence suggested that the transmission control and drug therapy may influence the preventive measures extensively as the host surrounding environment and pathogenic mechanism may contribute to the pandemic condition earlier in COVID-19 disease. Although, several animals identified as reservoir to date, however human-to-human transmission is well documented. Human beings are sustaining the virus in the communities and act as an amplifier of the virus. Human activities i.e., living with the patient, touching patient waste etc. in the surrounding of active patients or asymptomatic persons cause significant risk factors for transmission. On the other hand, drug target and mechanism to destroy the virus or virus inhibition depends on diversified approaches of drugs and different target for virus life cycle. This article describes the sustainable chemical preventive models understanding, requirements, technology adaptation and the implementation strategies in these pandemic-like situations. As the outbreak progresses, healthcare models focused on transmission control through disinfections and sanitization based on risk calculations. Identification of the most suitable target of drugs and regional control model of transmission are of high priority. In the early stages of an outbreak, availability of epidemiological information is important to encourage preventive measures efforts by public health authorities and provide robust evidence to guide interventions. Here, we have discussed the level of adaptations in technology that research professionals display toward their public health preventive models. We should compile a representative data set of adaptations that humans can consider for transmission control and adopt for viruses and their hosts. Overall, there are many aspects of the chemical science and technology in virus preventive measures. Herein, the most recent advances in this context are discussed, and the possible reasons behind the sustainable preventive model are presented. This kind of sustainable preventive model having adaptation and implementation with green chemistry system will reduce the shedding of the virus into the community by eco-friendly methods, and thus the risk of transmission and infection progression can be mitigated.
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| 44. |
- Mishra, Prashant, et al.
(författare)
-
Electrocatalytic biofuel cell based on highly efficient metal-polymer nano-architectured bioelectrodes
- 2017
-
Ingår i: Nano Energy. - : ELSEVIER SCIENCE BV. - 2211-2855 .- 2211-3282. ; 39, s. 601-607
-
Tidskriftsartikel (refereegranskat)abstract
- Bioenergy based devices are rapidly gaining significant research interest because of growing quest for future alternative energy resources, but most of the existing technologies suffer from poor electron transfer and slow mass transport, which hinder the fabrication of realistic high-power devices. Using a versatile strategy, here we have demonstrated the fabrication of nanoparticle-polymer framework based bioelectrocatalytic interfaces which facilitate a high mass-transport and thus offers the simple construction of advanced enzyme-based biofuel cells. It has been shown that a gold nanoparticle-structured polyaniline network can be effectively used as an electrical cabling interface providing efficient electron transfer for bio-anode and cathode. The resulting bioelectrodes are capable of excellent diffusional mass-transport and thus can easily facilitate the design of new and highly efficient membrane-less advanced bioenergy devices. The biofuel cell delivers a high-power density of about 2.5 times (i.e., 685 mu W cm(-2)) and open circuit voltage of 760 mV compared to conventional conducting polymer-based biofuel cells.
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| 45. |
- Mishra, Sachin, et al.
(författare)
-
Stimuli-enabled zipper-like graphene interface for auto-switchable bioelectronics.
- 2017
-
Ingår i: Biosensors & bioelectronics. - : Elsevier. - 0956-5663 .- 1873-4235. ; 89, s. 305-311
-
Tidskriftsartikel (refereegranskat)abstract
- Graphene interfaces with multi-stimuli responsiveness are of particular interest due to their diverse super-thin interfacial behaviour, which could be well suited to operating complex physiological systems in a single miniaturised domain. In general, smart graphene interfaces switch bioelectrodes from the hydrophobic to hydrophilic state, or vice versa, upon triggering. In the present work, a stimuli encoded zipper-like graphene oxide (GrO)/polymer interface was fabricated with in situ poly(N-isopropylacrylamide–co–diethylaminoethylmethylacrylate), i.e., poly(NIPAAm–co–DEAEMA) directed hierarchical self-assembly of GrO and glucose oxidase (GOx). The designed interface exhibited reversible on/off-switching of bio-electrocatalysis on changing the pH between 5 and 8, via phase transition from super hydrophilic to hydrophobic. The study further indicated that the zipper-like interfacial bioelectrochemical properties could be tuned over a modest change of temperature (i.e., 20–40 °C). The resulting auto-switchable interface has implications for the design of novel on/off-switchable biodevices with ‘in-built’ self-control.
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| 46. |
|
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| 47. |
- Mondal, Debasish, et al.
(författare)
-
Electrospun Nanomatrix for Tissue Regeneration
- 2012
-
Ingår i: Biomedical Materials and Diagnostic Devices. - USA : John Wiley & Sons. - 9781118030141 ; , s. 577-596
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration
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| 48. |
- Mondal, Debasish, et al.
(författare)
-
Nanofibers Based Biomedical Devices
- 2012
-
Ingår i: Intelligent Nanomaterials. - USA : John Wiley & Sons. - 9780470938799 ; , s. 679-714
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The last three decades have seen extraordinary advances in the generation of new materials based on both fundamental elements and composites, driven by advances in synthetic chemistry and often drawing inspiration from nature. The concept of an intelligent material envisions additional functionality built into the molecular structure, such that a desirable response occurs under defined conditions.Divided into 4 parts: Inorganic Materials; Organic Materials; Composite Materials; and Biomaterials, the 22 chapters cover the latest research and developments in the processing, properties, and applications of intelligent nanomaterials. Included are molecular device materials, biomimetic materials, hybrid-type functionalized polymers-composite materials, information-and energy-transfer materials, as well as environmentally friendly materials.
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| 49. |
- Nordin, Anis, et al.
(författare)
-
Label-free Detection of Prostate Cancer Biomarker
- 2014
-
Ingår i: 24<sup>th </sup>Anniversary World Congress on Biosensors – Biosensors 2014. - : Elsevier.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Prostate cancer is common and a frequent cause of cancer death, especially for American men. Most prostate cancers progress very slowly and while on the average about 30% of American males develop prostate cancer, only 3% die from the disease. The disparity in the statistics indicates that a more effective screening method is required to differentiate the aggressive form of prostate cancer that causes mortality in patients. In this work, a label-free, novel microelectromechanical (MEMS) biosensor for detection of cysteine, a prostate cancer biomarker is presented. This biosensor merges two biosensing techniques, namely resonant frequency measurements and electrochemical impedance spectroscopy (EIS) on a single biosensor. The sensor is based on the innovative placement of the working microelectrodes for EIS technique as the top electrode of a quartz crystal microbalance (QCM) resonator. The QCM acoustic wave sensor consists of a thin AT-cut quartz substrate with two gold electrodes on both sides. The top metal electrode used for generating the acoustic wave is also used for EIS measurements of the biosensor, as illustrated in Fig. 1. The surfaces of the gold electrodes are modified using molecularly-imprinted polymers. Electrochemical methods were used to monitor the self-assembly of cysteine on the gold surface. The thiol-gold self-assembled layer causes impedance and mass change, which was characterised by EIS and acoustic-wave methods, respectively. Preliminary tests were performed on this sensor using cysteine in both phosphate buffer saline and human serum.
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| 50. |
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