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- Glintborg, B., et al.
(författare)
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Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries
- 2018
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Ingår i: Scandinavian Journal of Rheumatology. - : Informa UK Limited. - 0300-9742 .- 1502-7732. ; 47:6, s. 465-474
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Large-scale observational cohorts may be used to study the effectiveness and rare side effects of biological disease-modifying anti-rheumatic drugs (bDMARDs) in ankylosing spondylitis (AS), but may be hampered by differences in baseline characteristics and disease activity across countries. We aimed to explore the research infrastructure in the five Nordic countries regarding bDMARD treatment in AS. Method: This observational cohort study was based on data from biological registries in Denmark (DANBIO), Sweden (SRQ/ARTIS), Finland (ROB-FIN), Norway (NOR-DMARD), and Iceland (ICEBIO). Data were collected for the years 2010-2016. Registry coverage, registry inventory (patient characteristics, disease activity measures), and national guidelines for bDMARD prescription in AS were described per country. Incident (first line) and prevalent bDMARD use per capita, country, and year were calculated. In AS patients who started first line bDMARDs during 2010-2016 (n = 4392), baseline characteristics and disease activity measures were retrieved. Results: Registry coverage of bDMARD-treated patients ranged from 60% to 95%. All registries included extensive prospectively collected data at patient level. Guidelines regarding choice of first line drug and prescription patterns varied across countries. During the period 2010-2016 prevalent bDMARD use increased (p < 0.001), whereas incident use tended to decrease (p for trend < 0.004), with large national variations (e.g. 2016 incidence: Iceland 10.7/100 000, Finland 1.7/100 000). Baseline characteristics were similar regarding C-reactive protein, but differed for other variables, including the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (range 3.5-6.3) and Ankylosing Spondylitis Disease Activity Score (ASDAS) (2.7-3.8) (both p < 0.0001). Conclusion: Collaboration across the five Nordic biological registries regarding bDMARD use in AS is feasible but national differences in coverage, prescription patterns, and patient characteristics must be taken into account depending on the scientific question.
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- Cederwall, Bo, et al.
(författare)
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Collective rotational-vibrational transition in the very neutron-deficient nuclei (171,172)-Pt
- 1998
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Ingår i: Physics Letters B. - AMSTERDAM, NETHERLANDS : ELSEVIER SCIENCE. - 0370-2693 .- 1873-2445. ; 443:1-4, s. 69-76
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Tidskriftsartikel (refereegranskat)abstract
- Excited states have been identified for the first time in very neutron deficient Pt-171.172 nuclei using the recoil-or-decay tagging technique. The ground-state band in Pt-172 has been established up to I-pi = 8+. A similar level sequence, presumably built on the I-pi = 13/2(+) state, is observed for Pt-171. The data are compared with theoretical calculations based on the mean field approach and the random phase approximation and are put into the context of the systematics of platinum isotopes. (C) 1998 Elsevier Science B.V. All rights reserved.
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- Bark, R A, et al.
(författare)
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Coexistence of triaxial and prolate shapes in Ir-171
- 1999
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 657:2, s. 113-133
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in Ir-171 have been observed for the first time. Gamma-rays were assigned to the nucleus by the recoil-decay tagging method, The ground-state band has a structure consistent with an h(11/2) proton coupled to a core of large triaxial deformation. At high spins, a bandcrossing occurs which is interpreted as a change in shape to a prolate deformation, Band-mixing calculations are performed for Ir171-175. These show that shape-coexistence between triaxial and prolate states in these nuclei follows the same systematics found in their Pt and Os neighbours. The systematics are also compared with deformations calculated for Ir171-179 using the code "Ultimate Cranker". Dipole bands were also observed, but tilted axis cranking calculations suggest that they are associated with a collective rotation.
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- Bark, R A, et al.
(författare)
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Bandcrossings in Os-171
- 1999
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 646:4, s. 399-413
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Tidskriftsartikel (refereegranskat)abstract
- The nucleus Os-171 has been populated using the reaction Sn-116(Ni-58,2pn). Four new bands are identified, and the previously known bands are extended in spin, to a maximum of 53/2 (h) over bar. One- and three-quasiparticle configurations are identified, and beta, gamma, and octupole configurations are assigned tentatively. The effects of a possible intruder configuration on the negative parity bands are tested using band-mixing calculations.
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- Juutinen, S, et al.
(författare)
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Band structures in Ba-132
- 1995
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Ingår i: PHYSICAL REVIEW C-NUCLEAR PHYSICS. - : AMER INST PHYSICS. ; 52:6, s. 2946-2954
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Excited states of Ba-132 were studied in an experiment utilizing the Sn-124(C-13,5n) reaction at a beam energy of 65.5 MeV. The level scheme of Ba-132 was considerably extended from what was previously known. Evidence is presented for neutron h(11/2) alig
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