| 1. |
- Chierici, Melissa, 1968, et al.
(författare)
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The impact of biogeochemical processes and environmental factors on the calcium carbonate saturation state in the Circumpolar Flaw Lead in the Amundsen Gulf, Arctic Ocean. : Controls on calcium carbonate in the Arctic Ocean
- 2011
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Ingår i: Journal of Geophysical Research-Oceans. - 2156-2202. ; 116:C00G09
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Tidskriftsartikel (refereegranskat)abstract
- We report on measurements across an annual cycle of carbon dioxide system parameters in the polar mixed layer (PML) of the circumpolar flaw lead in the Amundsen Gulf, Arctic Ocean. From these and other properties (nitrate, S, T) of the PML, we found that biological processes (photosynthesis and respiration) accounted for about 50% of the monthly variations in the carbonate ion concentration, [CO32−] and Ω, the saturation state of these waters with respect to calcite (ΩCa) and aragonite (ΩAr). Vertical mixing and salinity changes had equal impacts over the annual cycle. The impact of sea ice meltwater resulted in decreasing Ω values in summer, but most of this change was offset by the Ω increase as a result of CO2 drawdown during biological photosynthesis.
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| 2. |
- Locke, Adam E, et al.
(författare)
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Genetic studies of body mass index yield new insights for obesity biology.
- 2015
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 197-401
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Tidskriftsartikel (refereegranskat)abstract
- Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
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| 3. |
- Lu, Yingchang, et al.
(författare)
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
- 2016
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GRB14, IGF2BP1, PLA2G6, CRTC1) were novel associations with BF%. Seven loci showed a larger effect on BF% than on BMI, suggestive of a primary association with adiposity, while five loci showed larger effects on BMI than on BF%, suggesting association with both fat and lean mass. In particular, the loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.
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| 4. |
- Matias, Marisa, et al.
(författare)
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Profiles of Parental Burnout Around the Globe : Similarities and Differences Across 36 Countries
- 2023
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Ingår i: Cross-cultural research. - 1069-3971 .- 1552-3578. ; 57:5, s. 499-538
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Tidskriftsartikel (refereegranskat)abstract
- Parental burnout (PB) is a pervasive phenomenon. Parenting is embedded in cultural values, and previous research has shown the role of individualism in PB. In this paper, we reanalyze previously collected data to identify profiles based on the four dimensions of PB, and explore whether these profiles vary across countries’ levels of collectivistic-individualistic (COL-IND) values. Our sample comprised 16,885 individuals from 36 countries (73% women; 27% men), and we used a latent profile approach to uncover PB profiles. The findings showed five profiles: Fulfilled, Not in PB, Low risk of PB, High risk of PB and Burned out. The profiles pointed to climbing levels of PB in the total sample and in each of the three country groups (High COL/Low IND, Medium COL-IND, Low COL/High IND). Exploratory analyses revealed that distinct dimensions of PB had the most prominent roles in the climbing pattern, depending on the countries’ levels of COL/IND. In particular, we found contrast to be a hallmark dimension and an indicator of severe burnout for individualistic countries. Contrary to our predictions, emotional distance and saturation did not allow a clear differentiation across collectivistic countries. Our findings support several research avenues regarding PB measurement and intervention.
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| 5. |
- Roskam, Isabelle, et al.
(författare)
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Parental Burnout Around the Globe : a 42-Country Study
- 2021
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Ingår i: Affective science. - : Springer Science and Business Media LLC. - 2662-205X .- 2662-2041. ; 2, s. 58-79
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Tidskriftsartikel (refereegranskat)abstract
- High levels of stress in the parenting domain can lead to parental burnout, a condition that has severe consequences for both parents and children. It is not yet clear, however, whether parental burnout varies by culture, and if so, why it might do so. In this study, we examined the prevalence of parental burnout in 42 countries (17,409 parents; 71% mothers; Mage = 39.20) and showed that the prevalence of parental burnout varies dramatically across countries. Analyses of cultural values revealed that individualistic cultures, in particular, displayed a noticeably higher prevalence and mean level of parental burnout. Indeed, individualism plays a larger role in parental burnout than either economic inequalities across countries, or any other individual and family characteristic examined so far, including the number and age of children and the number of hours spent with them. These results suggest that cultural values in Western countries may put parents under heightened levels of stress.Supplementary Information: The online version contains supplementary material available at 10.1007/s42761-020-00028-4.
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| 6. |
- Roskam, Isabelle, et al.
(författare)
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Three reasons why parental burnout is more prevalent in individualistic countries : a mediation study in 36 countries
- 2024
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Ingår i: Social Psychiatry and Psychiatric Epidemiology. - : Springer Nature. - 0933-7954 .- 1433-9285. ; 59, s. 681-694
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThe prevalence of parental burnout, a condition that has severe consequences for both parents and children, varies dramatically across countries and is highest in Western countries characterized by high individualism.MethodIn this study, we examined the mediators of the relationship between individualism measured at the country level and parental burnout measured at the individual level in 36 countries (16,059 parents).ResultsThe results revealed three mediating mechanisms, that is, self-discrepancies between socially prescribed and actual parental selves, high agency and self-directed socialization goals, and low parental task sharing, by which individualism leads to an increased risk of burnout among parents.ConclusionThe results confrm that the three mediators under consideration are all involved, and that mediation was higher for self-discrepancies between socially prescribed and actual parental selves, then parental task sharing, and lastly selfdi-rected socialization goals. The results provide some important indications of how to prevent parental burnout at the societal level in Western countries.
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| 7. |
- Shadwick, Elisabeth, et al.
(författare)
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Seasonal variability of the inorganic C in the Amundsen Gulf.
- 2011
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Ingår i: Limnology and Oceanography. ; 56:1, s. 303-322
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Tidskriftsartikel (refereegranskat)abstract
- During a year-round occupation of Amundsen Gulf in the Canadian Arctic Archipelago dissolved inorganic and organic carbon (DIC, DOC), total alkalinity (TA), partial pressure of CO2 (pCO2) and related parameters were measured over a full annual cycle. A two-box model was used to identify and assess physical, biological, and chemical processes responsible for the seasonal variability of DIC, DOC, TA, and pCO2. Surface waters were undersaturated with respect to atmospheric CO2 throughout the year and constituted a net sink of 1.2 mol C m22 yr21, with ice coverage and ice formation limiting the CO2 uptake during winter. CO2 uptake was largely driven by under ice and open-water biological activity, with high subsequent export of organic matter to the deeper water column. Annual net community production (NCP) was 2.1 mol C m22 yr21. Approximately one-half of the overall NCP during the productive season (4.1 mol C m22 from Apr through Aug) was generated by under-ice algae and amounted to 1.9 mol C m22 over this period. The surface layer was autotrophic, while the overall heterotrophy of the system was fueled by either sedimentary or lateral inputs of organic matter.
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| 8. |
- Shadwick, EH, et al.
(författare)
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Seasonal variability of the inorganic carbon system in the Amundsen Gulf region of the southeastern Beaufort Sea
- 2011
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Ingår i: LIMNOLOGY AND OCEANOGRAPHY. - 0024-3590. ; 56:1, s. 303-322
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Tidskriftsartikel (refereegranskat)abstract
- Abstract During a year-round occupation of Amundsen Gulf in the Canadian Arctic Archipelago dissolved inorganic and organic carbon (DIC, DOC), total alkalinity (TA), partial pressure of CO2 (pCO2) and related parameters were measured over a full annual cycle. A two-box model was used to identify and assess physical, biological, and chemical processes responsible for the seasonal variability of DIC, DOC, TA, and pCO2. Surface waters were undersaturated with respect to atmospheric CO2 throughout the year and constituted a net sink of 1.2 mol C m22 yr21, with ice coverage and ice formation limiting the CO2 uptake during winter. CO2 uptake was largely driven by under ice and open-water biological activity, with high subsequent export of organic matter to the deeper water column. Annual net community production (NCP) was 2.1 mol C m22 yr21. Approximately one-half of the overall NCP during the productive season (4.1 mol C m22 from Apr through Aug) was generated by under-ice algae and amounted to 1.9 mol C m22 over this period. The surface layer was autotrophic, while the overall heterotrophy of the system was fueled by either sedimentary or lateral inputs of organic matter.
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| 9. |
- Shungin, Dmitry, et al.
(författare)
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New genetic loci link adipose and insulin biology to body fat distribution.
- 2015
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 187-378
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Tidskriftsartikel (refereegranskat)abstract
- Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
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| 10. |
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| 11. |
- Thomas, H, et al.
(författare)
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Barium and carbon fluxes in the Canadian Arctic Archipelago
- 2011
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Ingår i: Journal of Geophysical Research - Oceans. - 0148-0227 .- 2156-2202. ; 116
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Tidskriftsartikel (refereegranskat)abstract
- The seasonal and spatial variability of dissolved Barium (Ba) in the Amundsen Gulf, southeastern Beaufort Sea, was monitored over a full year from September 2007 to September 2008. Dissolved Ba displays a nutrient-type behavior: the maximum water column concentration is located below the surface layer. The highest Ba concentrations are typically observed at river mouths, the lowest concentrations are found in water masses of Atlantic origin. Barium concentrations decrease eastward through the Canadian Arctic Archipelago. Barite (BaSO4) saturation is reached at the maximum dissolved Ba concentrations in the subsurface layer, whereas the rest of the water column is undersaturated. A three end-member mixing model comprising freshwater from sea-ice melt and rivers, as well as upper halocline water, is used to establish their relative contributions to the Ba concentrations in the upper water column of the Amundsen Gulf. Based on water column and riverine Ba contributions, we assess the depletion of dissolved Ba by formation and sinking of biologically bound Ba (bio-Ba), from which we derive an estimate of the carbon export production. In the upper 50 m of the water column of the Amundsen Gulf, riverine Ba accounts for up to 15% of the available dissolved Ba inventory, of which up to 20% is depleted by bio-Ba formation and export. Since riverine inputs and Ba export occur concurrently, the seasonal variability of dissolved Ba in the upper water column is moderate. Assuming a fixed organic carbon to bio-Ba flux ratio, carbon export out of the surface layer is estimated at 1.8 ± 0.45 mol C m−2 yr−1. Finally, we propose a climatological carbon budget for the Amundsen Gulf based on recent literature data and our findings, the latter bridging the surface and subsurface water carbon cycles.
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