| 1. |
- El-Seedi, Hesham R., et al.
(författare)
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Plant extracts and compounds for combating schistosomiasis
- 2023
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Ingår i: Phytochemistry Reviews. - : Springer. - 1568-7767 .- 1572-980X. ; 22:6, s. 1691-1806
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Tidskriftsartikel (refereegranskat)abstract
- Schistosomiasis is a vector-borne water-based disease caused by Schistosoma blood flukes. It mostly affects people in low-income regions, 90% of reported cases being in developing countries. Schistosoma has a complex lifecycle, alternately infecting mammalian hosts and snails. The snails hosting the parasite are the most viable targets. Selective preparations for reducing the parasite pool in snails and infected water are required as current molluscicides are also nontoxic to other organisms, including fish, and thus affect food supplies in infected areas. Plants (e.g. Annona crassiflora Mart., A. muricata L., and A. montana Macfad.) are attractive potential sources as alternative molluscicides and novel entity to treat the disease owned to their diverse biologically potent compounds including; saponins, alkaloids, terpenoids, and tannins. Additionally, they can be locally cultivated, providing income for farmers and reducing treatment costs. Here, we review plants, plant extracts and isolated compounds that have shown activities against the host snails or Schistosoma in various parts of its life cycle. Plants have a lot of potential and will continue to contribute feasible, effective medicines and/or pesticides; more research is warranted to fully explore their future applications.
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| 2. |
- El-Seedi, Hesham R., et al.
(författare)
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Recent insights into the biosynthesis and biological activities of natural xanthones
- 2010
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Ingår i: Current Medicinal Chemistry. - : Bentham Science Publishers Ltd.. - 0929-8673 .- 1875-533X. ; 17:9, s. 854-901
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Forskningsöversikt (refereegranskat)abstract
- This review focuses on recent advances in our understanding of the complex biosynthetic pathways and diverse biological activities of naturally occurring xanthones. The biosynthesis section covers studies published from 1989 to 2008 on xanthone production in plants and fungi, while the bioactivity review presents tabulated activities of more than 250 xanthones described in studies published from 2001 to 2008, together with structural information and indications of their wide-ranging potential uses as pharmacological tools. A large number of relevant papers have been published on these subjects (128 cited here), illustrating the diversity of the xanthones and their possible uses.
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| 3. |
- El-Seedi, Hesham, et al.
(författare)
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Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids
- 2012
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Ingår i: Journal of Agricultural and Food Chemistry. - : American Chemical Society (ACS). - 0021-8561 .- 1520-5118. ; 60:44, s. 10877-10895
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Forskningsöversikt (refereegranskat)abstract
- Hydroxycinnamic acids are the most widely distributed phenolic acids in plants. Broadly speaking, they can be defined as compounds derived from cinnamic acid. They are present at high concentrations in many food products, including fruits, vegetables, tea, cocoa, and wine. A diet rich in hydroxycinnamic acids is thought to be associated with beneficial health effects such as a reduced risk of cardiovascular disease. The impact of hydroxycinnamic acids on health depends on their intake and pharmacokinetic properties. This review discusses their chemistry, biosynthesis, natural sources, dietary intake, and pharmacokinetic properties.
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| 4. |
- El-Seedi, H, et al.
(författare)
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Cyclopeptide alkaloids
- 2007
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Ingår i: Phytochemistry Reviews. - : Springer Science and Business Media LLC. - 1568-7767 .- 1572-980X. ; 6:1, s. 143-165
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Tidskriftsartikel (refereegranskat)abstract
- In this review, we discuss cyclopeptide alkaloids, their plant origin, and the way of separation, spectral analysis done for structure elucidation, stereochemistry, and their biological activities. In addition, we discuss briefly the chemosystematic significance of the cyclopeptide alkaloids based on their discovery in the family Olacaceae.
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| 5. |
- El-Seedi, Hesham R., et al.
(författare)
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Naturally occurring xanthones; latest investigations : isolation, structure elucidation and chemosystematic significance
- 2009
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Ingår i: Current Medicinal Chemistry. - : Bentham Science Publishers Ltd.. - 0929-8673 .- 1875-533X. ; 16:20, s. 2581-2626
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Forskningsöversikt (refereegranskat)abstract
- In this review, an updated literature survey covering the reports of naturally occurring xanthones in the period of 2005-2008 is presented. In some 143 studies, the isolation of 264 different xanthones from 36 plant species (representing 15 genera in 6 families of higher plants), 7 species of fungi, and 1 lichen species were reported. Of these, 122 compounds were isolated for the first time from nature. We discuss plant origin, the way of separation, and spectral analysis done for structure elucidation, along with a brief discussion of the chemosystematic significance.
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| 6. |
- El-Seedi, Hesham R., et al.
(författare)
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Plants mentioned in the Islamic Scriptures (Holy Qur'an and Ahadith) : Traditional uses and medicinal importance in contemporary times
- 2019
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Ingår i: Journal of Ethnopharmacology. - : Elsevier. - 0378-8741 .- 1872-7573. ; 243
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Forskningsöversikt (refereegranskat)abstract
- Ethnopharmacological relevance: Over the past thousand years, Islamic physicians have collected cultural, philosophical, sociological and historical backgrounds for understanding diseases and medications. The Prophet Mohammed (Peace Be Upon Him (PBUH) said: "There is no disease that Allah has created, except that Allah also has created its cure." Therefore, Islamic scholars are encouraged to explore and use both traditional and modern forms of medicine. Aim of the study: (1) To identify some of the medicinal plants mentioned in the Holy Qur'an and Ahadith textbooks of the period 700-1500 AD; (2) to compare them with presently used traditional medicines; (3) to evaluate their value based on modern research; and (4) to investigate the contributions of Islamic scholars to the development of the scientific branches, particularly medicine. Materials and methods: A literature search was performed relating to 12 medicinal plants mentioned in the Holy Qur'an and Ahadith using textbooks, Al-Azhar scholars, published articles, the plant list website (http://www.theplantlist.org/), the medicinal plant names services website (http://mpns.kew.org/mpns-portal/) and web databases (PubMed, Science Direct, and Google Scholar). Results and discussion: The Islamic Golden Age was a step towards modern medicine, with unique insights and multi-disciplinary aspects. Traditional Islamic Medicine has had a significant impact on the development of various medical, scientific and educational activities. Innumerable Muslim and non-Muslim physicians have built on the strong foundation of Traditional Islamic Medicine by translating the described natural remedies and effects. The influences of different ancient cultures on the traditional uses of natural products were also documented in Islamic Scriptures in the last part of the second millennium. The divine teachings of Islam combine natural and practical healing and incorporate inherited science and technology. Conclusion: In this review, we discuss Traditional Islamic Medicine with reference to both medical recommendations mentioned in the Holy Qur'an and Prophetic Traditional Medicine (al-Tibb al-Nabawi). Although the molecular mechanisms and functions of some of the listed medicinal plants and their derivatives have been intensively studied, some traditional remedies have yet to be translated into clinical applications.
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| 7. |
- Marpaung, D, et al.
(författare)
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Development of a Broadband and Squint-Free Ku-Band Phased Array Antenna System for Airborne Satellite Communications
- 2011
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Ingår i: Future Aeronautical Communications, Edited by Simon Plass, Chapter 10. - 9789533076256
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Future Aeronautical Communications, Edited by Simon Plass, Chapter 10: Development of a Broadband and Squint-Free Ku-Band Phased Array Antenna System for Airborne Satellite CommunicationsNovel avionic communication systems are required for various purposes, for example to increase the flight safety and operational integrity as well as to enhance the quality of service to passengers on board. To serve these purposes, a key technology that is essential to be developed is an antenna system that can provide broadband connectivity within aircraft cabins at an affordable price. Currently, in the European Commission (EC) 7th Framework Programme SANDRA project (SANDRA, 2011), a development of such an antenna system is being carried out. The system is an electronically-steered phased-array antenna (PAA) with a low aerodynamic profile. The reception of digital video broadcasting by satellite (DVB-S) signal which is in the frequency range of 10.7-12.75 GHz (Ku-band) is being considered. In order to ensure the quality of service provided to the passengers, the developed antenna should be able to receive the entire DVB-S band at once while complying with the requirements of the DVB-S system (Morello & Mignone, 2006). These requirements, as will be explained later, dictate a broadband antenna system where the beam is squint-free, i.e. no variation of beam pointing direction for all the frequencies in the desired band. Additionally, to track the satellite, the seamless tunability of the beam pointing direction of this antenna is also required. In this work, a concept of optical beamforming (Riza & Thompson, 1997) is implemented to provide a squint-free beam over the entire Ku-band for all the desired pointing directions. The optical beamformer itself consists of continuously tunable optical delay lines that enable seamless tunability of the beam pointing direction.
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