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- Vineis, Paolo, et al.
(författare)
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Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study
- 2007
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Ingår i: Environmental Health. - 1476-069X. ; 6
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Tidskriftsartikel (refereegranskat)abstract
- Background: Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution. Methods: We have estimated exposure to Environmental Tobacco Smoke (ETS) and to air pollution in never smokers and ex-smokers in a large prospective study in 10 European countries (European Prospective Investigation into Cancer and Nutrition)(N = 520,000). We report estimates of the proportion of lung cancers attributable to ETS and air pollution in this population. Results: The proportion of lung cancers in never-and ex-smokers attributable to ETS was estimated as between 16 and 24%, mainly due to the contribution of work-related exposure. We have also estimated that 5-7% of lung cancers in European never smokers and ex-smokers are attributable to high levels of air pollution, as expressed by NO2 or proximity to heavy traffic roads. NO2 is the expression of a mixture of combustion (traffic-related) particles and gases, and is also related to power plants and waste incinerator emissions. Discussion: We have estimated risks of lung cancer attributable to ETS and traffic-related air pollution in a large prospective study in Europe. Information bias can be ruled out due to the prospective design, and we have thoroughly controlled for potential confounders, including restriction to never smokers and long-term ex-smokers. Concerning traffic-related air pollution, the thresholds for indicators of exposure we have used are rather strict, i.e. they correspond to the high levels of exposure that characterize mainly Southern European countries (levels of NO2 in Denmark and Sweden are closer to 10-20 ug/m(3), whereas levels in Italy are around 30 or 40, or higher). Therefore, further reduction in exposure levels below 30 ug/m(3) would correspond to additional lung cancer cases prevented, and our estimate of 5-7% is likely to be an underestimate. Overall, our prospective study draws attention to the need for strict legislation concerning the quality of air in Europe.
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- Nicholl, Matt, et al.
(författare)
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An extremely energetic supernova from a very massive star in a dense medium
- 2020
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Ingår i: Nature Astronomy. - : Springer Science and Business Media LLC. - 2397-3366. ; 4, s. 893-899
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Tidskriftsartikel (refereegranskat)abstract
- The interaction of a supernova with a circumstellar medium (CSM) can dramatically increase the emitted luminosity by converting kinetic energy to thermal energy. In 'superluminous' supernovae of type IIn-named for narrow hydrogen lines(1) in their spectra-the integrated emission can reach(2-6) similar to 10(51) erg, attainable by thermalizing most of the kinetic energy of a conventional supernova. A few transients in the centres of active galaxies have shown similar spectra and even larger energies(7,8), but are difficult to distinguish from accretion onto the supermassive black hole. Here we present a new event, SN2016aps, offset from the centre of a low-mass galaxy, that radiated greater than or similar to 5 x 10(51) erg, necessitating a hyper-energetic supernova explosion. We find a total (supernova ejecta + CSM) mass likely exceeding 50-100 M-circle dot, with energy greater than or similar to 10(52) erg, consistent with some models of pair-instability supernovae or pulsational pair-instability supernovae-theoretically predicted thermonuclear explosions from helium cores >50 M-circle dot. Independent of the explosion mechanism, this event demonstrates the existence of extremely energetic stellar explosions, detectable at very high redshifts, and provides insight into dense CSM formation in the most massive stars.
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- Vigna-Taglianti, F, et al.
(författare)
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Aircraft Noise Exposure and Use of Medication
- 2009
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Ingår i: EPIDEMIOLOGY. - : Ovid Technologies (Wolters Kluwer Health). - 1044-3983. ; 20:6, s. S237-S237
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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