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| 2. |
- Obers, Niels A., et al.
(författare)
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Quantum gravity phenomenology at the dawn of the multi-messenger era—A review
- 2022
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Ingår i: Progress in Particle and Nuclear Physics. - : Elsevier BV. - 0146-6410 .- 1873-2224. ; 125
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Forskningsöversikt (refereegranskat)abstract
- The exploration of the universe has recently entered a new era thanks to the multi-messenger paradigm, characterized by a continuous increase in the quantity and quality of experimental data that is obtained by the detection of the various cosmic messengers (photons, neutrinos, cosmic rays and gravitational waves) from numerous origins. They give us information about their sources in the universe and the properties of the intergalactic medium. Moreover, multi-messenger astronomy opens up the possibility to search for phenomenological signatures of quantum gravity. On the one hand, the most energetic events allow us to test our physical theories at energy regimes which are not directly accessible in accelerators; on the other hand, tiny effects in the propagation of very high energy particles could be amplified by cosmological distances. After decades of merely theoretical investigations, the possibility of obtaining phenomenological indications of Planck-scale effects is a revolutionary step in the quest for a quantum theory of gravity, but it requires cooperation between different communities of physicists (both theoretical and experimental). This review, prepared within the COST Action CA18108 “Quantum gravity phenomenology in the multi-messenger approach”, is aimed at promoting this cooperation by giving a state-of-the art account of the interdisciplinary expertise that is needed in the effective search of quantum gravity footprints in the production, propagation and detection of cosmic messengers.
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| 4. |
- Fages, A., et al.
(författare)
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Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series
- 2019
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Ingår i: Cell. - : Elsevier BV. - 0092-8674. ; 177:6
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Tidskriftsartikel (refereegranskat)abstract
- Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (>= 1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modem legacy of past equestrian civilisations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modem breeding impacted genetic diversity more dramatically than the previous millennia of human management.
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| 5. |
- Menkveld, Albert J., et al.
(författare)
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Nonstandard Errors
- 2024
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Ingår i: JOURNAL OF FINANCE. - : Wiley-Blackwell. - 0022-1082 .- 1540-6261. ; 79:3, s. 2339-2390
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Tidskriftsartikel (refereegranskat)abstract
- In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty-nonstandard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for more reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants.
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| 6. |
- Toledo-Redondo, S., et al.
(författare)
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Kinetic Interaction of Cold and Hot Protons With an Oblique EMIC Wave Near the Dayside Reconnecting Magnetopause
- 2021
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Ingår i: Geophysical Research Letters. - : American Geophysical Union (AGU). - 0094-8276 .- 1944-8007. ; 48:8
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Tidskriftsartikel (refereegranskat)abstract
- We report observations of the ion dynamics inside an Alfven branch wave that propagates near the reconnecting dayside magnetopause. The measured frequency, wave normal angle and polarization are consistent with the predictions of a dispersion solver. The magnetospheric plasma contains hot protons (keV), cold protons (eV), plus some heavy ions. While the cold protons follow the magnetic field fluctuations and remain frozen-in, the hot protons are at the limit of magnetization. The cold protons exchange energy back and forth, adiabatically, with the wave fields. The cold proton velocity fluctuations contribute to balance the Hall term fluctuations in Ohm's law, and the wave E field has small ellipticity and right-handed polarization. The dispersion solver indicates that increasing the cold proton density facilitates propagation and amplification of these waves at oblique angles, as for the observed wave. Plain Language Summary The Earth's magnetosphere is a very dilute cloud of charged particles that are trapped in the Earth's magnetic field. This cloud is surrounded by the solar wind, another very dilute gas that flows supersonically throughout the solar system. These two plasmas can couple to each other via magnetic reconnection, a fundamental plasma process that occurs at the dayside region of the interface between the two plasmas. When reconnection occurs, large amounts of energy and particles enter the magnetosphere, driving the near Earth space dynamics and generating, for instance, aurorae. The magnetospheric plasma sources are the solar wind and the Earth's ionosphere. Multiple plasma populations can be found inside the Earth's magnetosphere, depending on the plasma origin and its time history, as well as the magnetospheric forcing of the solar wind. In this study, we show how the presence of multiple particle populations at the interface between the solar wind and the magnetosphere modifies the properties of the waves that propagate there. Waves are known to play a fundamental role in converting energy and heating these very dilute charged gas clouds.
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| 7. |
- Chen, L. -J, et al.
(författare)
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Electron Bulk Acceleration and Thermalization at Earth's Quasiperpendicular Bow Shock
- 2018
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Ingår i: Physical Review Letters. - : American Physical Society. - 0031-9007 .- 1079-7114. ; 120:22
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Tidskriftsartikel (refereegranskat)abstract
- Electron heating at Earth's quasiperpendicular bow shock has been surmised to be due to the combined effects of a quasistatic electric potential and scattering through wave-particle interaction. Here we report the observation of electron distribution functions indicating a new electron heating process occurring at the leading edge of the shock front. Incident solar wind electrons are accelerated parallel to the magnetic field toward downstream, reaching an electron-ion relative drift speed exceeding the electron thermal speed. The bulk acceleration is associated with an electric field pulse embedded in a whistler-mode wave. The high electron-ion relative drift is relaxed primarily through a nonlinear current-driven instability. The relaxed distributions contain a beam traveling toward the shock as a remnant of the accelerated electrons. Similar distribution functions prevail throughout the shock transition layer, suggesting that the observed acceleration and thermalization is essential to the cross-shock electron heating.
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| 8. |
- Hoban, Sean, et al.
(författare)
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Genetic diversity goals and targets have improved, but remain insufficient for clear implementation of the post-2020 global biodiversity framework
- 2023
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Ingår i: Conservation Genetics. - : Springer Science and Business Media LLC. - 1566-0621 .- 1572-9737. ; 24:2, s. 181-191
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Tidskriftsartikel (refereegranskat)abstract
- Genetic diversity among and within populations of all species is necessary for people and nature to survive and thrive in a changing world. Over the past three years, commitments for conserving genetic diversity have become more ambitious and specific under the Convention on Biological Diversity’s (CBD) draft post-2020 global biodiversity framework (GBF). This Perspective article comments on how goals and targets of the GBF have evolved, the improvements that are still needed, lessons learned from this process, and connections between goals and targets and the actions and reporting that will be needed to maintain, protect, manage and monitor genetic diversity. It is possible and necessary that the GBF strives to maintain genetic diversity within and among populations of all species, to restore genetic connectivity, and to develop national genetic conservation strategies, and to report on these using proposed, feasible indicators.
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| 10. |
- Bentow, C., et al.
(författare)
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International multi-center evaluation of a novel chemiluminescence assay for the detection of anti-dsDNA antibodies
- 2016
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Ingår i: Lupus. - : SAGE PUBLICATIONS LTD. - 0961-2033 .- 1477-0962. ; 25:8, s. 864-872
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Anti-double stranded desoxyribonucleic acid (anti-dsDNA) antibodies are considered fairly specific for systemic lupus erythematosus (SLE) and their quantification is useful for the clinical management of SLE patients. We assessed the diagnostic performance of the QUANTA Flash dsDNA chemiluminescent immunoassay (CIA) in comparison to an ELISA, using patients from five participating countries. The main focus was to evaluate the correlation between anti-dsDNA antibody results from the CIA and global SLE disease activity, as measured by the SLE Disease Activity Index 2000 (SLEDAI-2K). Patients and methods: A total of 1431 samples (SLE, n=843; disease controls, n=588) from five countries (Canada, USA, Portugal, Sweden and Spain) were tested with QUANTA Flash dsDNA (Inova Diagnostics, San Diego, CA, USA). Data obtained with the QUANTA Lite dsDNA SC ELISA (Inova Diagnostics) were available for samples from three sites (Canada, USA and Sweden, n=566). The SLEDAI-2K scores were available for 805 SLE patients and a cut-off ofamp;gt;4 was used to define active disease. Results: QUANTA Flash dsDNA had a sensitivity of 54.3% for the diagnosis of SLE, combined with 89.8% specificity. Anti-dsDNA antibody levels were significantly higher (pamp;lt;0.0001) in active SLE (SLEDAI-2Kamp;gt;4; n=232; median value 83.0IU/mL) versus the inactive patients (n=573; median value 22.3IU/mL), and the SLEDAI-2K scoring correlated with their dsDNA antibody levels (Spearmans rho=0.44, pamp;lt;0.0001). Similar but less pronounced findings were also found for the ELISA, in relation to disease activity. Conclusions: The QUANTA Flash dsDNA assay showed good clinical performance in a large international multi-center study. Additionally, the strong correlation between anti-dsDNA antibody results and SLEDAI-2K scores supported the potential utility of QUANTA Flash dsDNA for monitoring disease activity.
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| 12. |
- Aubert, Salome, et al.
(författare)
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Global Matrix 3.0 Physical Activity Report Card Grades for Children and Youth: Results and Analysis From 49 Countries
- 2018
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Ingår i: Journal of Physical Activity and Health. - : HUMAN KINETICS PUBL INC. - 1543-3080 .- 1543-5474. ; 15, s. S251-S273
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Tidskriftsartikel (refereegranskat)abstract
- Background: Accumulating sufficient moderate to vigorous physical activity is recognized as a key determinant of physical, physiological, developmental, mental, cognitive, and social health among children and youth (aged 5-17 y). The Global Matrix 3.0 of Report Card grades on physical activity was developed to achieve a better understanding of the global variation in child and youth physical activity and associated supports. Methods: Work groups from 49 countries followed harmonized procedures to develop their Report Cards by grading 10 common indicators using the best available data. The participating countries were divided into 3 categories using the United Nations human development index (HDI) classification (low or medium, high, and very high HDI). Results: A total of 490 grades, including 369 letter grades and 121 incomplete grades, were assigned by the 49 work groups. Overall, an average grade of "C-," "D+," and "C-" was obtained for the low and medium HDI countries, high HDI countries, and very high HDI countries, respectively. Conclusions: The present study provides rich new evidence showing that the situation regarding the physical activity of children and youth is a concern worldwide. Strategic public investments to implement effective interventions to increase physical activity opportunities are needed.
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| 13. |
- Aubert, Salome, et al.
(författare)
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Report Card Grades on the Physical Activity of Children and Youth Comparing 30 Very High Human Development Index Countries
- 2018
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Ingår i: Journal of Physical Activity and Health. - : HUMAN KINETICS PUBL INC. - 1543-3080 .- 1543-5474. ; 15, s. S298-S314
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Tidskriftsartikel (refereegranskat)abstract
- Background: To better understand the childhood physical inactivity crisis, Report Cards on physical activity of children and youth were prepared concurrently in 30 very high Human Development Index countries. The aim of this article was to present, describe, and compare the findings from these Report Cards. Methods: The Report Cards were developed using a harmonized process for data gathering, assessing, and assigning grades to 10 common physical activity indicators. Descriptive statistics were calculated after converting letter grades to interval variables, and correlational analyses between the 10 common indicators were performed using Spearmans rank correlation coefficients. Results: A matrix of 300 grades was obtained with substantial variations within and between countries. Low grades were observed for behavioral indicators, and higher grades were observed for sources of influence indicators, indicating a disconnect between supports and desired behaviors. Conclusion: This analysis summarizes the level and context of the physical activity of children and youth among very high Human Development Index countries, and provides additional evidence that the situation regarding physical activity in children and youth is very concerning. Unless a major shift to a more active lifestyle happens soon, a high rate of noncommunicable diseases can be anticipated when this generation of children reaches adulthood.
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| 14. |
- Hasegawa, H., et al.
(författare)
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Generation of Turbulence in Kelvin-Helmholtz Vortices at the Earth's Magnetopause : Magnetospheric Multiscale Observations
- 2020
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Ingår i: Journal of Geophysical Research - Space Physics. - 2169-9380 .- 2169-9402. ; 125:3
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Tidskriftsartikel (refereegranskat)abstract
- The Kelvin-Helmholtz instability (KHI) at Earth's magnetopause and associated turbulence are suggested to play a role in the transport of mass and momentum from the solar wind into Earth's magnetosphere. We investigate electromagnetic turbulence observed in Kelvin-Helmholtz vortices encountered at the dusk flank magnetopause by the Magnetospheric Multiscale (MMS) spacecraft under northward interplanetary magnetic field (IMF) conditions in order to reveal its generation process, mode properties, and role. A comparison with another MMS event at the dayside magnetopause with reconnection but no KHI signatures under a similar IMF condition indicates that while high-latitude magnetopause reconnection excites a modest level of turbulence in the dayside low-latitude boundary layer, the KHI further amplifies the turbulence, leading to magnetic energy spectra with a power law index -5/3 at magnetohydrodynamic scales even in its early nonlinear phase. The mode of the electromagnetic turbulence is analyzed with a single-spacecraft method based on Ampere's law, developed by Bellan (2016, https://doi.org/10.1002/2016JA022827), for estimating wave vectors as a function of spacecraft frame frequency. The results suggest that the turbulence does not consist of propagating normal-mode waves but is due to interlaced magnetic flux tubes advected by plasma flows in the vortices. The turbulence at sub-ion scales in the early nonlinear phase of the KHI may not be the cause of the plasma transport across the magnetopause but rather a consequence of three-dimensional vortex-induced reconnection, the process that can cause an efficient transport by producing tangled reconnected field lines. Plain Language Summary Turbulence is ubiquitous in nature and plays an important role in material mixing and energy transport. Turbulence in space plasmas is characterized by fluctuations of flow velocity and/or electromagnetic fields over a broad frequency range and/or length scales and is believed to be the key to efficient plasma transport and heating. However, its generation mechanism is not fully understood because turbulence in space is often fully developed or already relaxed when observed. By analyzing high-resolution plasma and electromagnetic field data taken by the Magnetospheric Multiscale spacecraft, we study the generation process of electromagnetic turbulence at the outer boundary of Earth's magnetosphere, called the magnetopause, where either a flow shear-driven Kelvin-Helmholtz instability or magnetic reconnection or both could drive turbulence. It is shown that while dayside reconnection generates a modest level of turbulence at the magnetopause near noon, the flow shear instability further amplifies the turbulence at the flank magnetopause. Our analysis also suggests that the turbulence may not be the primary cause of plasma transport from solar wind into the magnetosphere but rather a consequence of the flow shear-induced reconnection that is likely the primary cause of plasma transport at the dayside flank under northward solar wind magnetic field conditions.
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| 15. |
- Hoban, Sean, et al.
(författare)
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Monitoring status and trends in genetic diversity for the Convention on Biological Diversity : An ongoing assessment of genetic indicators in nine countries
- 2023
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Ingår i: Conservation Letters. - 1755-263X. ; 16:3
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Tidskriftsartikel (refereegranskat)abstract
- Recent scientific evidence shows that genetic diversity must be maintained, managed, and monitored to protect biodiversity and nature's contributions to people. Three genetic diversity indicators, two of which do not require DNA-based assessment, have been proposed for reporting to the Convention on Biological Diversity and other conservation and policy initiatives. These indicators allow an approximation of the status and trends of genetic diversity to inform policy, using existing demographic and geographic information. Application of these indicators has been initiated and here we describe ongoing efforts in calculating these indicators with examples. We specifically describe a project underway to apply these indicators in nine countries, provide example calculations, address concerns of policy makers and implementation challenges, and describe a roadmap for further development and deployment, incorporating feedback from the broader community. We also present guidance documents and data collection tools for calculating indicators. We demonstrate that Parties can successfully and cost-effectively report these genetic diversity indicators with existing biodiversity observation data, and, in doing so, better conserve the Earth's biodiversity.
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| 16. |
- Teixidor F, Pedrajas J, Rojo I, Vinas C, Kivekaes R, Sillanpaeae R, Sivaev I, Bredgadze V, Sjöberg S
(författare)
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Chameleonic Capacity of [3,3'-Co(1,2-C2B9H11)2]- in Coordination. Generation of the Highly Uncommon S(thioether)- Na Bond
- 2003
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Ingår i: Organometallics. ; :22, s. 3414-3423
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Tidskriftsartikel (refereegranskat)
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