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- Wache, Christina, et al.
(författare)
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Myeloid-related protein 14 promote inflammation and injury in meningitis.
- 2015
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Ingår i: Journal of Infectious Diseases. - : Oxford University Press (OUP). - 1537-6613 .- 0022-1899. ; 212:2, s. 247-257
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Tidskriftsartikel (refereegranskat)abstract
- Neutrophilic inflammation often persists over days despite efficient antibiotic treatment and contributes to brain damage in bacterial meningitis. We proposed here that MRP14, an abundant cytosolic protein in myeloid cells, acts as an endogenous danger signal, driving inflammation and aggravating tissue injury.
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