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Sökning: WFRF:(Wadman I)

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1.
  • Rabbitts, T H, et al. (författare)
  • Chromosomal translocations and leukaemia : a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis
  • 1997
  • Ingår i: Leukemia. - 0887-6924. ; 11:Suppl 3, s. 2-271
  • Tidskriftsartikel (refereegranskat)abstract
    • The LMO2 gene associated with T cell acute leukaemia has been used as an example of a gene activated by association with the T cell receptor genes after chromosomal translocations. The gene is shown to encode a LIM protein which is involved in protein interactions and during normal haematopoiesis is necessary for erythroid development. LMO2 has been shown to cause tumours when aberrantly expressed and to be able to heterodimerise with TAL1 to facilitate tumour development.
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2.
  • Wadman, Maria, et al. (författare)
  • Survival after operations for ischaemic bowel disease
  • 2000
  • Ingår i: European Journal of Surgery. - : Oxford University Press (OUP). - 1102-4151. ; 166:11, s. 872-877
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To find out what factors influence the outcome of operations for ischaemic bowel disease. Design: Retrospective study. Setting: University hospital, Sweden. Main outcome measures: Morbidity and mortality. Subjects: 74 patients, mean age 75 years (range 40-98), operated on for acute bowel ischaemia between 1987 and 1996. Results: A total of 75 emergency operations were done, including 42 bowel-resections, one percutaneous transluminal angioplasty, and one thrombectomy. Thirty-one patients had exploration alone because of extensive gangrene. These explorations were performed in 11 of 14 (79%) patients aged >84 years; 18 of 40 (45%) patients aged 71-84 years and 2 of 21 (9%) patients aged <71 years, (p < 0.001). Of the 14 patients over 84 years old only one survived more than 30 days, compared with 12 of 40 (30%) aged 71-84 years, and 17 of 21 (81%) younger than 71 years (p < 0.001). Operation within 6 hours of admission resulted in significantly better survival compared with operations done after more than 6 hours delay (p = 0.04). Conclusions: Advanced age was a strong risk factor for death after operation for ischaemic bowel disease, and there was a higher incidence of unresectable gangrene. Delay in surgical intervention was associated with increasing mortality.
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  • Resultat 1-2 av 2
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tidskriftsartikel (2)
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refereegranskat (2)
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Forster, A. (1)
Larson, R. (1)
Wadman, Maria (1)
Axelson, H. (1)
Warren, A. (1)
Syk, I. (1)
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Elmstahl, S. (1)
Osada, H (1)
Rabbitts, T H (1)
Grutz, G (1)
Lavenir, I (1)
Valge-Archer, V (1)
Wadman, I (1)
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Lunds universitet (2)
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Engelska (2)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (2)

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