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| 3. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 4. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 5. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 6. |
- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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- Anwar, Muhammad Waseem, et al.
(författare)
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A Model-Driven Framework for Design and Analysis of Vehicle Suspension Systems
- 2022
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Ingår i: <em>Communications in Computer and Information Science</em>. - Cham : Springer Science and Business Media Deutschland GmbH. - 9783031163012 ; , s. 197-208
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Konferensbidrag (refereegranskat)abstract
- The design and implementation of vehicle suspension systems is complex and time-consuming process that usually leads to production delays. Although different Model Driven Engineering (MDE) technologies like EAST-ADL/AUTOSAR are frequently applied to expedite vehicle development process, a framework particularly dealing with design and analysis of vehicle suspension is hard to find in literature. This rises the need of a framework that not only supports the analysis of suspension system at higher abstraction level but also complements the existing standards like EAST-ADL. In this article, a Model driven framework for Vehicle Suspension System (MVSS) is proposed. Particularly, a meta-model containing major vehicle suspension aspects is introduced. Subsequently, a modeling editor is developed using Eclipse Sirius platform. This allows the modeling of both simple as well as complex vehicle suspension systems with simplicity. Moreover, Object Constraint Language (OCL) is utilized to perform early system analysis in modeling phase. Furthermore, the target MATLAB-Simulink models are generated from source models, using model-to-text transformations, to perform advanced system analysis. The application of proposed framework is demonstrated through real life Audi A6L Hydraulic active suspension use case. The initial results indicate that proposed framework is highly effective for the design and analysis of vehicle suspension systems. In addition to this, the analysis results could be propagated to EAST-ADL toolchains to support full vehicle development workflow.
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| 12. |
- Siddique, Waseem, et al.
(författare)
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Flow structure, heat transfer and pressure drop in varying aspect ratio two-pass rectangular smooth channels
- 2012
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Ingår i: Heat and Mass Transfer. - : Springer Science and Business Media LLC. - 0947-7411 .- 1432-1181. ; 48:5, s. 735-748
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Tidskriftsartikel (refereegranskat)abstract
- Two-pass channels are used for internal cooling in a number of engineering systems e.g., gas turbines. Fluid travelling through the curved path, experiences pressure and centrifugal forces, that result in pressure driven secondary motion. This motion helps in moving the cold high momentum fluid from the channel core to the side walls and plays a significant role in the heat transfer in the channel bend and outlet pass. The present study investigates using Computational Fluid Dynamics (CFD), the flow structure, heat transfer enhancement and pressure drop in a smooth channel with varying aspect ratio channel at different divider-to-tip wall distances. Numerical simulations are performed in two-pass smooth channel with aspect ratio W-in/H = 1:3 at inlet pass and W-out/H = 1:1 at outlet pass for a variety of divider-to-tip wall distances. The results show that with a decrease in aspect ratio of inlet pass of the channel, pressure loss decreases. The divider-to-tip wall distance (W-el) not only influences the pressure drop, but also the heat transfer enhancement at the bend and outlet pass. With an increase in the divider-to-tip wall distance, the areas of enhanced heat transfer shifts from side walls of outlet pass towards the inlet pass. To compromise between heat transfer and pressure drop in the channel, W-el/H = 0.88 is found to be optimum for the channel under study.
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| 13. |
- Siddique, Waseem, et al.
(författare)
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On flow structure, heat transfer and pressure drop in varying aspect ratio two-pass rectangular channel with ribs at 45 degrees
- 2013
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Ingår i: Heat and Mass Transfer. - : Springer Science and Business Media LLC. - 0947-7411 .- 1432-1181. ; 49:5, s. 679-694
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Tidskriftsartikel (refereegranskat)abstract
- To increase the thermal efficiency of gas turbines, inlet temperature of gas is increased. This results in the requirement of cooling of gas turbine blades and vanes. Internal cooling of gas turbine blades and vanes is one of several options. Two-pass channels are provided with ribs to enhance heat transfer at the expense of an increased pressure drop. The space in the blade is limited and requires channels with small aspect ratios. Numerical simulations have been performed to investigate heat transfer, flow field and pressure loss in a two-pass channel equipped with 45A degrees ribs with aspect ratio (W-in/H) equal to 1:3 in the inlet pass and 1:1 in the outlet pass with both connected together with a 180A degrees bend. The results are compared with a higher aspect ratio channel (W-in/H = 1:2, inlet pass). In the ribbed channel, a decrease in pressure drop was observed with a decrease in the aspect ratio of the channel. The smaller aspect ratio channel not only allows using more cooling channels in the blade, but also results in more heat transfer enhancement. The divider-to-tip wall distance (W-el) has influence on the pressure drop, as well as on the heat transfer enhancement at the bend and outlet pass. Heat transfer decreases with decrease in aspect ratio of the inlet pass of the two-pass channel. With increase in divider-to-tip wall distance, heat transfer tries to attain a constant value.
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