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| 2. |
- Dujon, B, et al.
(författare)
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The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
- 1997
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 387:6632, s. 98-102
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Tidskriftsartikel (refereegranskat)abstract
- Chromosome XV was one of the last two chromosomes of Saccharomyces cerevisiae to be discovered(1). It is the third-largest yeast chromosome after chromosomes XII and IV, and is very similar in size to chromosome VII. It alone represents 9% of the yeast genome (8% if ribosomal DNA is included). When systematic sequencing of chromosome XV was started, 93 genes or markers were identified, and most of them were mapped(2). However, very little else was known about chromosome XV which, in contrast to shorter chromosomes, had not been the object of comprehensive genetic or molecular analysis. It was therefore decided to start sequencing chromosome XV only in the third phase of the European Yeast Genome Sequencing Programme, after experience was gained on chromosomes III, XI and II (refs 3-5). The sequence of chromosome XV has been determined from a set of partly overlapping cosmid clones derived from a unique yeast strain, and physically mapped at 3.3-kilobase resolution before sequencing. As well as numerous new open reading frames (ORFs) and genes encoding tRNA or small RNA molecules, the sequence of 1,091,283 base pairs confirms the high proportion of orphan genes and reveals a number of ancestral and successive duplications with other yeast chromosomes.
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| 3. |
- Björk, Göran, 1956, et al.
(författare)
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Bathymetry and deep-water exchange across the central Lomonosov Ridge at 88°-89°N
- 2007
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Ingår i: Deep-Sea Research I. - : Elsevier BV. ; 54, s. 1197-1208
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Tidskriftsartikel (refereegranskat)abstract
- Seafloor mapping of the central Lomonosov Ridge using a multibeam echo-sounder during the Beringia/Healy–Oden Trans-Arctic Expedition (HOTRAX) 2005 shows that a channel across the ridge has a substantially shallower sill depth than the 2500 m indicated in present bathymetric maps. The multibeam survey along the ridge crest shows a maximum sill depth of about 1870 m. A previously hypothesized exchange of deep water from the Amundsen Basin to the Makarov Basin in this area is not confirmed. On the contrary, evidence of a deep-water flow from the Makarov to the Amundsen Basin was observed, indicating the existence of a new pathway for Canadian Basin Deep Water toward the Atlantic Ocean. Sediment data show extensive current activity along the ridge crest and along the rim of a local Intra Basin within the ridge structure.
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| 4. |
- Scherer, SW, et al.
(författare)
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Human chromosome 7: DNA sequence and biology
- 2003
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 300:5620, s. 767-772
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Tidskriftsartikel (refereegranskat)abstract
- DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. This approach enabled the discovery of candidate genes for developmental diseases including autism.
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| 7. |
- Rudels, B., et al.
(författare)
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The interaction between waters from the Arctic Ocean and the Nordic Seas north of Fram Strait and along the East Greenland Current: results from the Arctic Ocean-02 Oden expedition
- 2005
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Ingår i: Journal of Marine Systems. - : Elsevier BV. - 0924-7963. ; 55:1-2, s. 1-30
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Tidskriftsartikel (refereegranskat)abstract
- In spring 2002, the Swedish icebreaker Oden conducted an extensive oceanographic survey of the East Greenland Current from north of Fram Strait to South of Denmark Strait as a part of the Arctic Ocean 2002 programme to study the Nordic Seas, while RV Knorr of Woods Hole worked in the ice-free parts. The Oden survey concentrated on water mass formation in ice covered water and the interactions between the water of the Arctic Ocean and the Nordic Seas. The CTD observations made on Oden are presented by following the Oden cruise track. They describe all major, and many of the more subtle, mixing processes occurring in the Arctic Mediterranean Sea. In Storfjorden, ice formation and brine rejection had created the highest bottom salinities observed in the last 20 years. The Atlantic Water (AW) entering the Arctic Ocean close to Svalbard was cooled and freshened down to 600 m implying that dense, brine enriched shelf water from the northern Svalbard shelf had convected into the Atlantic core. The upper part of the Atlantic Water was cooled by heat loss to the atmosphere and to ice melt. About 30% of the heat went to ice melt leading to a less saline upper layer that eventually forms the embryo of the Arctic Ocean halocline water. North of the Yermak Plateau Atlantic Water as well as Arctic Intermediate Water (AIW) and Nordic Seas Deep Water (NDW) were seen to enter the Arctic Ocean. North of 81 degrees N the Arctic Ocean water masses dominated west of 0 degrees E, while recirculating waters from the south were observed first at 79 degrees N. The properties of the intermediate and deep waters exiting the Arctic Ocean in the East Greenland Current changed considerably from Fram Strait to the Greenland Sea indicating interactions with recirculating waters. The salinity of the Polar Surface Water (PSW) increased from Fram Strait to Denmark Strait but the thickness of the low salinity upper layer also increased and the freshwater content appeared to be conserved. The Denmark Strait overflow plume was stratified and several of the different water masses present at the sill in Denmark Strait at the Oden crossing could contribute to the overflow. Arctic Atlantic Water (AAW) and Recirculating Atlantic Water (RAW) as well as Polar Intermediate Water (PIW) would supply the less dense part, while the ultimate origin of densest component of the overflow, found at the Iceland side of the trench, still is an open question. The low salinity lid found on top of the overflow plume in the Irminger Sea suggests that entrainment of ambient water into the overflow plume was small. (c) 2004 Elsevier B.V. All rights reserved.
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