| 1. |
- Schael, S, et al.
(författare)
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Precision electroweak measurements on the Z resonance
- 2006
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Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 427:5-6, s. 257-454
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Forskningsöversikt (refereegranskat)abstract
- We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLID experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, m(Z) and Gamma(Z), and its couplings to fermions, for example the p parameter and the effective electroweak mixing angle for leptons, are precisely measured: m(Z) = 91.1875 +/- 0.0021 GeV, Gamma(Z) = 2.4952 +/- 0.0023 GeV, rho(l) = 1.0050 +/- 0.0010, sin(2)theta(eff)(lept) = 0.23153 +/- 0.00016. The number of light neutrino species is determined to be 2.9840 +/- 0.0082, in agreement with the three observed generations of fundamental fermions. The results are compared to the predictions of the Standard Model (SM). At the Z-pole, electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its SM expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the Z-pole data are also used to predict the mass of the top quark, m(t) = 173(+10)(+13) GeV, and the mass of the W boson, m(W) = 80.363 +/- 0.032 GeV. These indirect constraints are compared to the direct measurements, providing a stringent test of the SM. Using in addition the direct measurements of m(t) and m(W), the mass of the as yet unobserved SM Higgs boson is predicted with a relative uncertainty of about 50% and found to be less than 285 GeV at 95% confidence level. (c) 2006 Elsevier B.V. All rights reserved.
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| 2. |
- Reifarth, R., et al.
(författare)
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Nuclear astrophysics with radioactive ions at FAIR
- 2016
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Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
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Konferensbidrag (refereegranskat)abstract
- The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
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| 3. |
- Elsik, Christine G., et al.
(författare)
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The Genome Sequence of Taurine Cattle : A Window to Ruminant Biology and Evolution
- 2009
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 324:5926, s. 522-528
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Tidskriftsartikel (refereegranskat)abstract
- To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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| 4. |
- Ballan, M., et al.
(författare)
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Nuclear physics midterm plan at Legnaro National Laboratories (LNL)
- 2023
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Ingår i: European Physical Journal Plus. - 2190-5444. ; 138:8, s. 3-26
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Tidskriftsartikel (refereegranskat)abstract
- The next years will see the completion of the radioactive ion beam facility SPES (Selective Production of Exotic Species) and the upgrade of the accelerators complex at Istituto Nazionale di Fisica Nucleare – Legnaro National Laboratories (LNL) opening up new possibilities in the fields of nuclear structure, nuclear dynamics, nuclear astrophysics, and applications. The nuclear physics community has organised a workshop to discuss the new physics opportunities that will be possible in the near future by employing state-of-the-art detection systems. A detailed discussion of the outcome from the workshop is presented in this report.
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| 5. |
- Birney, Ewan, et al.
(författare)
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
- 2007
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7146, s. 799-816
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Tidskriftsartikel (refereegranskat)abstract
- We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function.
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| 6. |
- Liu, Xiaoyu, et al.
(författare)
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Evidence for enhanced neutron-proton correlations from the level structure of theN = Z + 1 nucleus 87Tc
-
Ingår i: PHYSICAL REVIEW C.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The low-lying excited states in the neutron-deficient N = Z + 1 nucleus 8743 Tc 44 have been studiedvia the fusion-evaporation reaction 54 Fe( 36 Ar, 2n1p) 87 Tc at the Grand Accélérateur National d’IonsLourds (GANIL), France. The AGATA spectrometer was used in conjunction with the auxiliaryNEDA, Neutron Wall, and DIAMANT detector arrays to measure coincident prompt γ-rays, neutrons, and charged particles emitted in the reaction. A level scheme of 87 Tc from the (9/2 +g.s. ) state to the (33/2 +)statewasestablishedbasedon6mutuallycoincidentγ-ray transitions. The con-1structed level structure exhibits a rotational behavior with a sharp back bending at ~ω ≈ 0.50 MeV. A decrease in alignment frequency and increase in alignment sharpness in the odd-mass isotonic chains around N = 44 is proposed as an effect of the enhanced isoscalar neutron-proton interactions in odd-mass nuclei when approaching the N = Z line.
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| 7. |
- Ertoprak, Aysegul, et al.
(författare)
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Evidence for octupole collectivity in 172Pt
- 2020
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Ingår i: European Physical Journal A. - : Springer. - 1434-6001 .- 1434-601X. ; 56:2
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the extremely neutron-deficient nucleus 172Pt were populated via 96Ru(78Kr,2p) and 92Mo(83Kr,3n) reactions. The level scheme has been extended up to an excitation energy of ~ 5 MeV and tentative spin-parity assignments up to Iπ = 18+. Linear polarization and angular distribution measurements were used to determine the electromagnetic E1 character of the dipole transitions connecting the positive-parity ground-state band with an excited side-band, firmly establishing it as a negative-parity band. The lowest member of this negative-parity structure was firmly assigned spin-parity 3-. In addition, we observed an E3 transition from this 3- state to the ground state, providing direct evidence for octupole collectivity in 172Pt. Large-scale shell model (LSSM) and total Routhian surface (TRS) calculations have been performed, supporting the interpretation of the 3- state as a collective octupole-vibrational state.
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| 8. |
- Joss, D. T., et al.
(författare)
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The influence of quasineutron configurations on 161Ta and nearby odd-A nuclei
- 2011
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Ingår i: AIP Conf. Proc.. - : AIP. - 9780735409835 ; , s. 43-48
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Konferensbidrag (refereegranskat)abstract
- Several strongly coupled bands in the neutron-deficient nucleus 161Ta have been identified and quasiparticle configuration assignments have been made on the basis of rotational alignments and cranked shell model calculations. The level scheme elucidated for 161Ta highlights the competition between the ν(h 9/2) and ν(i 13/2) orbitals to form the yrast spectrum. The band structures in 161Ta also provide new insights into the structural features of other heavy odd-A nuclei populated with much lower reaction cross sections in this region at the proton drip line.
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| 9. |
- Liu, X., et al.
(författare)
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Evidence for enhanced neutron-proton correlations from the levelstructure of the N= Z+ 1 nucleus 8743Tc44
- 2021
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Ingår i: Physical Review C. - : American Physical Society. - 2469-9985 .- 2469-9993. ; 104:2
-
Tidskriftsartikel (refereegranskat)abstract
- The low-lying excited states in the neutron-deficient N = Z + 1 nucleus (87)(43)Tcc(44) have been studied via the fusion-evaporation reaction Fe-54(Ar-36, 2n1p)Tc-87 at the Grand Accelerateur National d'Ions Lourds (GANIL), France. The AGATA spectrometer was used in conjunction with the auxiliary NEDA, Neutron Wall, and DIAMANT detector arrays to measure coincident prompt gamma rays, neutrons, and charged particles emitted in the reaction. A level scheme of Tc-87 from the (9/2(g.s.)(+)) state to the (33/2(1)(+)) state was established based on six mutually coincident gamma-ray transitions. The constructed level structure exhibits a rotational behavior with a sharp backbending at (h) over bar omega approximate to 0.50 MeV. A decrease in alignment frequency and increase in alignment sharpness in the odd-mass isotonic chains around N = 44 is proposed as an effect of the enhanced isoscalar neutron-proton interactions in odd-mass nuclei when approaching the N = Z line.
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| 10. |
- Liu, Xiaoyu, et al.
(författare)
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Evidence for spherical-oblate shape coexistence in Tc-87
- 2022
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Ingår i: Physical Review C. - : American Physical Society. - 2469-9985 .- 2469-9993. ; 106:3
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in the neutron-deficient nucleus Tc-87 have been studied via the fusion-evaporation reaction 54Fe(36Ar, 2n1p) Tc-87 at 115 MeV beam energy. The AGATA gamma-ray spectrometer coupled to the DIAMANT, NEDA, and Neutron Wall detector arrays for light-particle detection was used to measure the prompt coincidence of gamma rays and light particles. Six transitions from the deexcitation of excited states belonging to a new band in Tc-87 were identified by comparing gamma-ray intensities in the spectra gated under different reaction channel selection conditions. The constructed level structure was compared with the shell model and total Routhian surface calculations. The results indicate that the new band structure in 87Tc is built on a spherical configuration, which is different from that assigned to the previously identified oblate yrast rotational band.
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| 11. |
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| 12. |
- Andgren, Karin, et al.
(författare)
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Low-spin collective behavior in the transitional nuclei Mo-86,Mo-88
- 2007
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 76:1, s. 014307-
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Tidskriftsartikel (refereegranskat)abstract
- Low-spin structures in Mo-86,Mo-88 were populated using the Ni-58(Ar-36, x alpha yp) heavy-ion fusion-evaporation reaction at a beam energy of 111 MeV. Charged particles and gamma rays were emitted in the reactions and detected by the DIAMANT CsI ball and the EXOGAM Ge array, respectively. In addition to the previously reported low-to-medium spin states in these nuclei, new low-spin structures were observed. Angular correlation and linear polarization measurements were performed in order to unambiguously determine the spins and parities of intensely populated states in Mo-88. Quasiparticle Random Phase Approximation (QRPA) calculations were performed for the first and second excited 2(+) states in Mo-86 and Mo-88. The results are in qualitative agreement with the experimental results, supporting a collective interpretation of the low-spin states for these transitional nuclei.
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| 13. |
- Fischer, S. M., et al.
(författare)
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Alignment delays in the N = Z nuclei Kr-72, Sr-76, and Zr-80
- 2001
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 8713:13
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Tidskriftsartikel (refereegranskat)abstract
- The ground state rotational bands of the N = Z nuclei Kr-72, Sr-76, and Zr-80 have been extended into the angular momentum region where rotation alignment of particles is normally expected. By measuring the moments of inertia of these bands we have observed a consistent increase in the rotational frequency required to start pair breaking, when compared to neighboring nuclei. Kr-72 shows the most marked effect. It has been widely suggested that these delayed alignments arise from np-pairing correlations. However, alignment frequencies are very sensitive to shape degrees of freedom and normal pairing, so the new experimental observations are still open to interpretation.
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| 14. |
- Shrine, N, et al.
(författare)
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Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
- 2023
-
Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 55:3, s. 410-
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Tidskriftsartikel (refereegranskat)abstract
- Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 participants, we identified 1,020 independent association signals implicating 559 genes supported by ≥2 criteria from a systematic variant-to-gene mapping framework. These genes were enriched in 29 pathways. Individual variants showed heterogeneity across ancestries, age and smoking groups, and collectively as a genetic risk score showed strong association with COPD across ancestry groups. We undertook phenome-wide association studies for selected associated variants as well as trait and pathway-specific genetic risk scores to infer possible consequences of intervening in pathways underlying lung function. We highlight new putative causal variants, genes, proteins and pathways, including those targeted by existing drugs. These findings bring us closer to understanding the mechanisms underlying lung function and COPD, and should inform functional genomics experiments and potentially future COPD therapies.
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| 15. |
- Kleinberger, G., et al.
(författare)
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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- 2014
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Ingår i: Science Translational Medicine. - : American Association for the Advancement of Science (AAAS). - 1946-6234 .- 1946-6242. ; 6:243
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Tidskriftsartikel (refereegranskat)abstract
- Genetic variants in the triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to Nasu-Hakola disease, Alzheimer's disease (AD), Parkinson's disease, amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and FTD-like syndrome without bone involvement. TREM2 is an innate immune receptor preferentially expressed by microglia and is involved in inflammation and phagocytosis. Whether and how TREM2 missense mutations affect TREM2 function is unclear. We report that missense mutations associated with FTD and FTD-like syndrome reduce TREM2 maturation, abolish shedding by ADAM proteases, and impair the phagocytic activity of TREM2-expressing cells. As a consequence of reduced shedding, TREM2 is virtually absent in the cerebrospinal fluid (CSF) and plasma of a patient with FTD-like syndrome. A decrease in soluble TREM2 was also observed in the CSF of patients with AD and FTD, further suggesting that reduced TREM2 function may contribute to increased risk for two neurodegenerative disorders.
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| 16. |
- Palacz, M, et al.
(författare)
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In-beam gamma-ray spectroscopy of Cd-103
- 1997
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Ingår i: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. - 0375-9474. ; 624:2, s. 210-224
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Excited states of Cd-103 were studied in the reaction Ni-58(Cr-50,4pn)Cd-103. The NORDBALL array with neutron and charged particle detectors was employed for the detection of gamma rays and light evaporated particles. The level scheme of Cd-103 was signif
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| 17. |
- Palacz, M, et al.
(författare)
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In beam gamma-ray spectroscopy of very neutron deficient odd-cadmium isotopes
- 1997
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Ingår i: Acta Physica Polonica B. - : ACTA PHYSICA POLONICA B, JAGELLONIAN UNIV, INST PHYSICS. - 0587-4254 .- 1509-5770. ; 28:1-2, s. 309-313
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the very neutron deficient odd cadmium isotopes Cd-99, Cd-101 and Cd-103 are discussed in terms of the nuclear shell model. Systematics of excited states in Cd99-109 is presented.
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| 18. |
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| 19. |
- Gadea, A., et al.
(författare)
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Spectroscopy at N=Z with EUROBALL III
- 1999
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Ingår i: AIP Conference Proceedings. - : AIP. - 1551-7616 .- 0094-243X. ; 495, s. 195-198
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Konferensbidrag (refereegranskat)abstract
- A complete study of the nuclear structure by means of gamma spectroscopy requires, in addition to the high resolution gamma measurement and accurate DCO's or angular distributions, the information concerning the Electric or Magnetic character of the transition. This information for transitions in nuclei far from stability valley is now reachable in the new generation of Ge-arrays based in composite detectors. EUROBALL III is a good example with the high polarization sensitivity of the 90 degrees ring of Clovers. The Polarization correlations PCO's measured in coincidence with the Cluster detectors permits to investigate transitions in weakly populated nuclei. In this contribution we present results on medium mass N=Z nuclei measured with EUROBALL III coupled with light particle ancillary detectors.
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| 20. |
- Ghazi Moradi, Farnaz, et al.
(författare)
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High-spin study of 162Ta
- 2011
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 84:6, s. 064312-
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the odd-odd neutron deficient nucleus (162)Ta (Z = 73, N = 89) have been studied for the first time. The gamma spectroscopy analysis using gamma - gamma - gamma coincidences revealed a strongly coupled rotational structure that was established up to large angular momentum states. The rotational band was assigned to the configuration pi h(11/2)[514]9/2 circle times nu i(13/2)[660]1/2 based on its rotational and electromagnetic properties. The data are interpreted within the framework of total Routhian surface calculations, which suggests an axially symmetric shape with a gamma-softminimum at beta(2) approximate to 0.16 and gamma approximate to 6 degrees. The crossing of the signature partners observed in heavier (N >= 91) odd-odd nuclides in this mass region is found to be absent at N = 89. This might be correlated with a change in S-band structure above the paired band crossing at these neutron numbers.
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| 21. |
- Kelsall, N. S., et al.
(författare)
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Testing mean-field models near the N=Z line : gamma-ray spectroscopy of the T-z=1/2 nucleus Kr-73
- 2002
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 65:4
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in the N=Z+1 nucleus Kr-73 have been investigated using the Ca-40(Ar-36,2pn) and Ca-40(Ca-40,alpha2pn) reactions at 145 and 160 MeV, respectively. gamma rays were detected using the Gammasphere array and events were recorded in coincidence with charged-particle and neutron detectors. The three previously observed bands were extended to high spin, and a new unfavored positive-parity band has been observed. The alignment characteristics and decay properties of the bands are all consistent with large-deformation prolate rotation, with no clear evidence for oblate bands or shape coexistence. This is quite different from neighboring Kr-72,Kr-74, indicating a strong shape-stabilizing role for the valence neutron. The experimental results are compared to extended total Routhian surface, cranked Nilsson Strutinsky, and cranked relativistic mean-field calculations. The results suggest that the paired calculations lack some important physics. Neutron-proton correlations may be the missing ingredient. There is also evidence for an unusual band crossing in the negative-parity bands, which may indicate the presence of T=0 pairing correlations. At high spin all the models can reproduce the experimental data.
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| 22. |
- Lagergren, Karin, et al.
(författare)
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gamma-soft shapes and quasiparticle excitations in Ta-161(73)88
- 2011
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 83:1, s. 014313-
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the neutron-deficient odd-Z nuclide Ta-161 were identified for the first time using the Cd-106(Ni-58,3p gamma) reaction at a beam energy of 270 MeV. The pi h(11/2) band, yrast at low spin, was observed up to (47/2(-)) and a further four strongly coupled bands have been established to high spin. Quasiparticle configuration assignments for the new band structures have been made on the basis of cranked shell model calculations. This work suggests that the negative-parity nu(f(7/2), h(9/2)) orbitals are responsible for the first rotational alignment in the pi h(11/2) band.
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| 23. |
- Palacz, M, et al.
(författare)
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In-beam gamma-ray spectroscopy of Cd-101
- 1996
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Ingår i: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. - 0375-9474. ; 608:2, s. 227-242
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Excited states of Cd-101 were studied in the reaction Ni-58(Cr-50,2p alpha n)Cd-101. The NORDBALL array with a Neutron Wall and a Silicon Ball was employed for the detection of gamma-rays and evaporated particles, The level scheme of Cd-101 was significan
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| 24. |
- Sakornsakolpat, Phuwanat, et al.
(författare)
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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
- 2019
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 51:3, s. 494-505
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Tidskriftsartikel (refereegranskat)abstract
- Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide association study in 35,735 cases and 222,076 controls from the UK Biobank and additional studies from the International COPD Genetics Consortium. We identified 82 loci associated with P < 5 x 10-8; 47 of these were previously described in association with either COPD or population-based measures of lung function. Of the remaining 35 new loci, 13 were associated with lung function in 79,055 individuals from the SpiroMeta consortium. Using gene expression and regulation data, we identified functional enrichment of COPD risk loci in lung tissue, smooth muscle, and several lung cell types. We found 14 COPD loci shared with either asthma or pulmonary fibrosis. COPD genetic risk loci clustered into groups based on associations with quantitative imaging features and comorbidities. Our analyses provide further support for the genetic susceptibility and heterogeneity of COPD.
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| 25. |
- Wilson, A. N., et al.
(författare)
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High-spin structures and alignment properties in Ce-126
- 2001
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 6305:5
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in Ce-126 have been observed with the GAMMASPHERE gamma -ray detector array, used in conjunction with the MICROBALL charged-particle detector. The reaction Zn-64(Zn-64, xpn alpha) (beam energy 260 MeV) was used to populate a wide range of nuclei in the neutron-deficient region with A approximate to 120. Ce-126 was populated via the 2p evaporation channel. The three previously observed bands have been extended to higher spins and some other structures have been identified. The yrast band shows evidence of a delayed neutron alignment occurring at a rotational frequency omega approximate to0.5 MeV/(h) over bar as observed in the neighboring odd-A nucleus Pr-127. One of the two excited bands shows evidence for a similar crossing at a slightly lower frequency and also exhibits a sudden gain in alignment at omega =0.57 MeV/(h) over bar. The third band may involve the coupling of a gamma -vibrational state. All three rotational bands are discussed in terms of standard and extended cranked shell model calculations.
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| 26. |
- Aktas, Özge, 1987-, et al.
(författare)
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First observation of γ-ray transitions in 111Mo
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X.
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the extremely neutron-rich nuclei 109Mo and 111Mo have been studied following nucleon knock-out reactions. Seven $\gamma$-ray transitions, some of them in prompt mutual coincidence, have been identified for the first time in 11Mo using the DALI2 and MINOS detector systems at the BigRIPS and ZeroDegree electromagnetic fragments separator at the RIBF, RIKEN, Japan. Total Routhian surface (TRS) and Particle- Plus Rotor calculations have been performed to investigate the predicted shape coexistence and its effect on the structure of nuclei in this region of the nuclear chart. Following the results of the calculations, theoretical level schemes are proposed for positive and negative parity states and compared with the experimental findings.
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| 27. |
- Andreyev, A. N., et al.
(författare)
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alpha decay of the new isotopes Rn-193,Rn-194
- 2006
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 74:6, s. 064303-
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Tidskriftsartikel (refereegranskat)abstract
- The new neutron-deficient isotopes Rn-193,Rn-194 have been identified in the complete fusion reaction Cr-52+Sm-144 -> Rn-196(*) at the velocity filter SHIP. The alpha-decay energy and half-life value of Rn-194 were determined to be E-alpha=7700(10) keV and T-1/2=0.78(16) ms, respectively. For Rn-193 the half-life of T-1/2=1.15(27) ms and two alpha lines at E-alpha 1=7685(15) keV, I-alpha 1=74(20)% and E-alpha 2=7875(20) keV, I-alpha 2=26(12)% were found. The decay pattern of Rn-193, which is substantially different from that of the heavier odd-A Rn isotopes, provides first experimental evidence for the long-predicted deformation in the very neutron-deficient Rn nuclei.
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| 28. |
- Antalic, S., et al.
(författare)
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The new isotopes in Po-Rn region
- 2007
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Ingår i: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 38:4, s. 1557-1560
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Tidskriftsartikel (refereegranskat)abstract
- This contribution reviews the results of the recent experiments at the velocity filter SHIP in GSI Darmstadt obtained in the region of neutron deficient isotopes from lead to radon. The data for new very neutron-deficient isotopes Po-187, Rn-193,Rn-194 and their decay properties are presented. The isotopes were produced and identified in the complete fusion reactions Ti-46+Sm-144 -> Po-187+3n and Cr-52+Sm-144 -> Rn-194,Rn-193+2,3n.
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| 29. |
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| 30. |
- Bäck, Torbjörn, et al.
(författare)
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Lifetime measurement of the first excited 2(+) state in (108)Te
- 2011
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 84:4, s. 041306-
-
Tidskriftsartikel (refereegranskat)abstract
- The lifetime of the first excited 2(+) state in the neutron deficient nuclide (108)Te has been measured for the first time, using a combined recoil decay tagging and recoil distance Doppler shift technique. The deduced reduced transition probability is B(E2;0(g.s.)(+) -> 2(+)) = 0.39(-0.04)(+0.05)e(2)b(2). Compared to previous experimental data on neutron deficient tellurium isotopes, the new data point constitutes a large step (six neutrons) toward the N = 50 shell closure. In contrast to what has earlier been reported for the light tin isotopes, our result for tellurium does not show any enhanced transition probability with respect to the theoretical predictions and the tellurium systematics including the new data is successfully reproduced by state-of-the-art shell model calculations.
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| 31. |
- CEDERKALL, J, et al.
(författare)
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1ST OBSERVATION OF EXCITED-STATES IN SB-108
- 1995
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 581:1, s. 189-204
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Tidskriftsartikel (refereegranskat)abstract
- A spectroscopic study of Sb-108 has been carried out as a part of a larger experiment where in total twenty-nine different residual nuclei were identified. This study gives the first information on excited levels in this nucleus. A low-lying two-quasi-particle multiplet together with some of the higher lying levels are discussed within the framework of the nuclear shell model. A rotational, strongly coupled, band is identified as, most likely, being built on the deformed pig9/2(-1) nuh11/2 configuration in accordance with total routhian surface calculations. Tentative spins and parities are presented as well as B(M1)/B(E2) ratios for some of the transitions in the strongly coupled band.
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| 32. |
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| 33. |
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| 34. |
- Duran-Castells, C., et al.
(författare)
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Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction
- 2023
-
Ingår i: Journal of Virology. - : American Society for Microbiology. - 0022-538X .- 1098-5514. ; 97:2
-
Tidskriftsartikel (refereegranskat)abstract
- Neurocognitive disorders are frequently reported in people living with HIV (PLWH) even with the introduction of combined antiretroviral treatment (cART). To identify biomarkers and potential therapeutic tools to target HIV infection in peripheral blood and in the central nervous system (CNS), plasma proteomics were applied in untreated chronic HIV-infected individuals with different levels of virus control. The implementation and access to combined antiretroviral treatment (cART) have dramatically improved the quality of life of people living with HIV (PLWH). However, some comorbidities, such as neurological disorders associated with HIV infection still represent a serious clinical challenge. Soluble factors in plasma that are associated with control of HIV replication and neurological dysfunction could serve as early biomarkers and as new therapeutic targets for this comorbidity. We used a customized antibody array for determination of blood plasma factors in 40 untreated PLWH with different levels of viremia and found sirtuin-2 (SIRT2), an NAD-dependent deacetylase, to be strongly associated with elevated viral loads and HIV provirus levels, as well as with markers of neurological damage (a-synuclein [SNCA], brain-derived neurotrophic factor [BDNF], microtubule-associated protein tau [MAPT], and neurofilament light protein [NFL]). Also, longitudinal analysis in HIV-infected individuals with immediate (n = 9) or delayed initiation (n = 10) of cART revealed that after 1 year on cART, SIRT2 plasma levels differed between both groups and correlated inversely with brain orbitofrontal cortex involution. Furthermore, targeting SIRT2 with specific small-molecule inhibitors in in vitro systems using J-LAT A2 and primary glial cells led to diminished HIV replication and virus reactivation from latency. Our data thus identify SIRT2 as a novel biomarker of uncontrolled HIV infection, with potential impact on neurological dysfunction and offers a new therapeutic target for HIV treatment and cure.IMPORTANCE Neurocognitive disorders are frequently reported in people living with HIV (PLWH) even with the introduction of combined antiretroviral treatment (cART). To identify biomarkers and potential therapeutic tools to target HIV infection in peripheral blood and in the central nervous system (CNS), plasma proteomics were applied in untreated chronic HIV-infected individuals with different levels of virus control. High plasma levels of sirtuin-2 (SIRT2), an NAD(+) deacetylase, were detected in uncontrolled HIV infection and were strongly associated with plasma viral load and proviral levels. In parallel, SIRT2 levels in the peripheral blood and CNS were associated with markers of neurological damage and brain involution and were more pronounced in individuals who initiated cART later in infection. In vitro infection experiments using specific SIRT2 inhibitors suggest that specific targeting of SIRT2 could offer new therapeutic treatment options for HIV infections and their associated neurological dysfunction.
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| 35. |
- Hadinia, Baharak, et al.
(författare)
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Identification of gamma rays from Au-172 and alpha decays of Au-172, Ir-168, and Re-164
- 2009
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 80:6, s. 064310-
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Tidskriftsartikel (refereegranskat)abstract
- The very neutron deficient odd-odd nucleus Au-172 was studied in reactions of 342 and 348 MeV Kr-78 beams with an isotopically enriched Ru-96 target. The alpha decays previously reported for Au-172 were confirmed and the decay chain extended down to Tm-152 through the discovery of a new alpha-decaying state in Re-164 [E-alpha=5623(10) keV; t(1/2)=864(-110)(+150) ms; b(alpha)=3(1)%]. Fine structure in these alpha decays of Au-172 and Ir-168 were identified. A new alpha-decaying state was also observed and assigned as the ground state in Au-172 [E-alpha=6762(10) keV; t(1/2)=22(-5)(+6) ms]. This decay chain was also correlated down to Tm-152 through previously reported alpha decays. Prompt gamma rays from excited states in Au-172 have been identified using the recoil-decay tagging technique. The partial level scheme constructed for Au-172 indicates that it has an irregular structure. Possible configurations of the alpha-decaying states in Au-172 are discussed in terms of the systematics of nuclei in this region and total Routhian surface calculations.
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| 36. |
- Jeppesen, H. B., et al.
(författare)
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Multi-quasiparticle states in (256)Rf
- 2009
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 79:3, s. 031303-
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in (256)Rf were populated via the Pb-208(Ti-50,2n) fusion-evaporation reaction. Delayed gamma-ray and electron decay spectroscopy was performed and three isomeric states in (256)Rf have been identified. A fourth low-energy nonyrast state was identified from the gamma-ray decay of one of the higher lying isomers. The states are interpreted as multi-quasiparticle excitations.
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| 37. |
- JOHNSON, A, et al.
(författare)
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HIGH-SPIN STUDIES NEAR SN-100 WITH NORDBALL - NEW RESULTS ON IN-102, IN-104 AND SB-108
- 1993
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Konferensbidrag (refereegranskat)abstract
- The NORDBALL detector array has been used in a gamma-ray spectroscopic study of neutron deficient nuclei close to 100Sn. A beam of 270 MeV 58Ni ions was used to bombard a target of Fe-54. Reaction channel separation was achieved with a 4pi charged particle Si-ball together with a 1pi neutron detector wall. Altogether 29 final nuclei were identified and excited states were observed for the first time in 8 of them. The weakest identified channel was 100Cd which represented 4.10(-3) % of the observed total yield. Level schemes Of 102In, 104In and 108Sb constructed from gamma-gamma-particle-coincidence and gamma-gamma-angular correlation analyses are presented. The observed structures are discussed in the framework of the nuclear shell-model. In 108Sb also a deformed, strongly coupled, level sequence is observed. This deformed structure is interpreted as built on a pig9/2(-1)xnuh11/2 configuration in agreement with TRS calculations.
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| 38. |
- Joss, D. T., et al.
(författare)
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Recoil decay tagging of gamma rays in the extremely neutron-deficient nucleus Os-162
- 2004
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Ingår i: Physical Review C. Nuclear Physics. - : American Physical Society. - 0556-2813 .- 1089-490X. ; 70:1
-
Tidskriftsartikel (refereegranskat)abstract
- The neutron-deficient nucleus Os-162, produced in the Cd-106(Ni-58,2n) reaction, has been studied using the JUROGAM gamma-ray spectrometer in conjunction with the RITU gas-filled separator and the GREAT focal plane spectrometer. gamma-ray transitions in Os-162 have been assigned for the first time through the application of the recoil decay tagging technique. The excitation energy of the 2(+) state and the tentative energy of the 8(+) state are discussed in terms of the systematic energy trends as the N=82 shell gap is approached.
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| 39. |
- Joss, D. T., et al.
(författare)
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Yrast spectroscopy in the neutron-deficient nucleus Os-169
- 2002
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Ingår i: Physical Review C. Nuclear Physics. - : American Physical Society. - 0556-2813 .- 1089-490X. ; 66:5
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in the neutron-deficient isotope Os-169 have been identified for the first time in an experiment using the Jurosphere gamma-ray spectrometer in conjunction with the Ritu gas-filled recoil separator. The problems associated with identifying neutron-deficient isotopes produced with low fusion cross sections against a high background of competing channels, including fission, have been overcome by using the recoil-decay tagging technique. The band structures observed in Os-169 are interpreted in the context of the systematics of neighboring nuclei and the predictions of cranked Woods-Saxon calculations. The systematics of the second (i(13/2))(2) neutron alignment in this region are discussed.
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| 40. |
- Kownacki, J, et al.
(författare)
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High-spin studies of the neutron deficient nuclei In-103, In-105, In-107, and In-109
- 1997
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 627:2, s. 239-258
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Tidskriftsartikel (refereegranskat)abstract
- High-spin states of the isotopes 103,105,107,109In have been investigated using in-beam γ-ray spectroscopic methods. Results from three different experiments are presented. Targets of 54Fe, 50Cr, and 92Mo were bombarded by a 270 and 261 MeV 58Ni beam and by a 95 MeV 19F beam, respectively. Reaction channel separation was achieved with a charged-particle detector array and in the first two experiments also with a 1π neutron detector system. As a result of these experiments the level schemes of 103,105,107,109In were significantly extended. Excited states of these odd-A indium isotopes are discussed within the framework of the nuclear shell model and the hole-core coupling scheme. The systematics of excited states of light odd-A indium isotopes is also discussed.
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| 41. |
- Kownacki, J, et al.
(författare)
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The isospin dependent p-n multiplets in the region of doubly magic Sn-100
- 1996
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Konferensbidrag (refereegranskat)abstract
- Experimental data on p-n multiplets appearing in the nuclei near double-magic Sn-100 accesible in heavy-ion fusion-evaporation experiments have been analyzed. Proton-rich nuclei in this region have been investigated using the NORDBALL array. A Ni-58 beams at energies of 270 Mev on Fe-54 and 261 MeV on Cr-50 targets were used. Reaction channel separation was achieved with a 4 pi charged particle multi-detector set-up together with a 1 pi neutron detector wall placed in the forward direction. On the basis of gamma gamma-coincidence and angular correlation relations a level schemes of several light Sn, In, Sb, Te and I nuclei were observed for the first time in the present experiment. The observed structure of nuclei are discussed in the framework of the nuclear shell-model. The p-n multiplets in the A similar to 100 region corresponding to the nucleon pairs with mixed configurations has been considered as a playground for the tests of the T = 0 and T = 1 parts of the effective interaction.
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| 42. |
- Lagergren, Karin, et al.
(författare)
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High-spin states in the proton-unbound nucleus Re-161
- 2006
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 74:2, s. 024316-
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in Re-161 were populated using the Cd-106(Ni-58, p2n) reaction at a beam energy of 270 MeV, resulting in the first observation of gamma rays emitted from this nucleus. The reaction products were separated from scattered beam and fission fragments by the gas-filled recoil separator RITU, and were implanted in the double-sided silicon strip detectors of the GREAT spectrometer. Prompt gamma rays were detected by the JUROGAM Ge detector array and were assigned to Re-161 based on alpha- and proton-decay tagging of the implanted reaction products. The near-yrast high-spin level structure, which was delineated to spins around 39/2, is discussed in the context of the total Routhian surface formalism. The level scheme is interpreted in terms of the alignment of h(9/2)/f(7/2) neutrons at lower spins, followed by excitations involving the pi h(11/2) subshell at higher spins.
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| 43. |
- LIDEN, F, et al.
(författare)
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ALIGNMENT PROCESSES IN CS-119, CS-121 AND CS-123
- 1992
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Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 550:2, s. 365-390
-
Tidskriftsartikel (refereegranskat)abstract
- Rotational band structures have been observed in the odd-A Cs isotopes 119Cs, 121Cs and 123Cs. The previously known bands have been extended to higher spin values and several new bands have been established. Alignments of both h11/2 protons and neutrons are seen. Of special interest are the alignment frequencies in the (tentative) [422]3/2+ and [404]9/2+ bands which indicate a configuration-dependent proton pairing. Furthermore, the variation of the interaction strength at the first band crossing in the h11/2 bands does not follow the standard cranked-shell-model predictions. This feature is in line with previous systematic observations of alignment processes in high-j intruder bands, and might infer an additional band mixing due to a neutron-proton interaction.(~)[GRAPHICS]
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| 44. |
- Mabala, G. K., et al.
(författare)
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Shears band with a large dynamic moment of inertia in Bi-197
- 2005
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Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 25:1, s. 49-55
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Bi-197 were studied with the AFRODITE gamma-ray array at iThemba LABS using the Ta-181(Ne-22, 6n) reaction at a beam energy of 125 MeV. A new shears band was found and linked to the low-lying states in Bi-197. Its dynamic moment of inertia, F (2), is considerably larger than the ((2)) of the shears bands in the neighbouring Pb isotopes. This is probably a result of the involvement of an additional high-K h(9/2) proton orbital.
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| 45. |
- Roux, D. G., et al.
(författare)
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Signature inversion in the yrast band of Ta-164
- 2002
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 65:1
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in Ta-164 were populated in the Nd-142(Al-27,5n)Ta-164 reaction and investigated using the AFRODITE spectrometer Arran. The yrast rotational decay sequence Lip to spin 21(-) is identified for the first time and assigned to the pi[514]9/2(-) x nu[660]1/2(+) configuration. A less intense. excited hand is also identified. Low-spin signature inversion is observed in the yrast band, and is compared with the extended total Routhian surface calculations. It is likely that quadrupole pairing plays a role in generating the anomalous signature splitting, but an additional mechanism apart front the assumed mean field and quadrupole pairing interaction may be required to account for the experimental data.
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| 46. |
- SEWERYNIAK, D, et al.
(författare)
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IN-BEAM SPECTROSCOPY AT THE PROTON-DRIP LINE - FIRST OBSERVATION OF EXCITED-STATES IN SB-106 AND SB-107
- 1994
-
Ingår i: Physics Letters B. - 0370-2693 .- 1873-2445. ; 321:4, s. 323-328
-
Tidskriftsartikel (refereegranskat)abstract
- Neutron deficient nuclei close to Sn-100 have been investigated in-beam using the NORDBALL detector array. A target of Fe-54 was bombarded with a beam of Ni-58 at 270 MeV. Evaporation residues were identified by detecting protons and alpha particles in a 4 pi charged particle multi-detector set-up and neutrons in a 1 pi neutron detector wall in coincidence with gamma rays. Excited states of the proton drip line nucleus Sb-106 and of Sb-107 were identified for the first time. The yrast level schemes constructed from gamma-gamma-particle coincidence and gamma-gamma angular correlation analysis are presented and discussed within the framework of the nuclear shell model.
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| 47. |
- Andreyev, A. N., et al.
(författare)
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New microsecond isomers in Bi-189,Bi-190
- 2001
-
Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 10:2, s. 129-133
-
Tidskriftsartikel (refereegranskat)abstract
- New microsecond isomers in the neutron-deficient isotopes Bi-189g,Bi-190 have been identified after in-flight separation by the velocity filter SHIP. The evaporation residues were identified on the basis of delayed recoil-gamma /X-ray, recoil-gamma /X-ray-alpha and excitation function measurements. The systematics of the [pi 1i(13/2)]13/2(+) excited states in the odd-mass Bi nuclei is discussed.
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| 48. |
- Andreyev, A. N., et al.
(författare)
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The discovery of a prolate-oblate-spherical shape triple of spin 0(+) states in the atomic nucleus Pb-186
- 2001
-
Ingår i: Nuclear Physics A. - : Elsevier BV. - 0375-9474 .- 1873-1554. ; 682, s. 482C-486C
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Tidskriftsartikel (refereegranskat)abstract
- Two excited J(pi)=0(+) states in Pb-186 populated in the a-decay of Po-190 have been identified through alpha -particle/conversion electron coincidences in an experiment at the velocity filter SHIP. The parent Po-190 nuclei have been produced in the Nd-142(Cr-52,4n)Po-190 complete fusion reaction, alpha -particle energies and branching ratios have been measured and hindrance factors were deduced. The observed states have been interpreted as the band heads of the known prolate and (yet unobserved) oblate rotational bands in Pb-186.
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| 49. |
- Bruce, A. M., et al.
(författare)
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Two-neutron alignment and shape changes in As-69
- 2000
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 6202:2
-
Tidskriftsartikel (refereegranskat)abstract
- The nucleus As-69 was Studied using the Ca-40(S-32,3p)As-69 reaction at a beam energy of 105 MeV. An extension of the band built on the g(9/2) orbital was observed to exhibit a band crossing at a rotational frequency of 0.511 MeV with an associated alignment of 7 (h) over bar. This alignment is interpreted as being due to a pair of g(9/2) neutrons. Total Routhian surface calculations have been carried out which confirm that the shape of this nucleus changes from oblate at low spin to a triaxial prolate shape at intermediate spin.
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| 50. |
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