| 1. |
- Yu, Xianxi, et al.
(författare)
-
Memory Devices via Unipolar Resistive Switching in Symmetric Organic-Inorganic Perovskite Nanoscale Heterolayers
- 2020
-
Ingår i: ACS Applied Nano Materials. - : AMER CHEMICAL SOC. - 2574-0970. ; 3:12, s. 11889-11896
-
Tidskriftsartikel (refereegranskat)abstract
- Organic-inorganic hybrid perovskite thin films with nanostructured polycrystalline grains have shown great potential in various nanoscale optoelectrical applications. Among them, the field of electrical memory has fallen behind due to insufficient knowledge of the related resistive switching characters and mechanisms. In the present work, switching behaviors of perovskite memory devices are systematically analyzed by comparing them with organic memory devices. We found that decreasing the conductivity of a polycrystalline perovskite thin layer would lead to unipolar switching behaviors, which is supplementary to the present perovskite memory family where bipolar switching is commonly reported. Moreover, our proposed symmetrical device with a nanoscale heterolayer structure enables us not only to achieve highly reproducible unipolar switching devices but also to settle the argument whether microconducting channels exist within perovskite memory devices through characterizing the microscopic morphological homogeneity. Surprisingly, the scanning electron microscopy results show that partial 10 pm large perovskite grains would be decomposed into various 100 nm small grains under high external bias, indicating the presence of microconducting channels. Furthermore, energy-dispersive X-ray spectroscopy results together with photoluminescence results of the perovskite thin film before and after applying bias are nearly identical, demonstrating that microconducting channels are formed without any difference in compositions or optical properties. Our discoveries provide a practical strategy to achieve electrical storage via organic-inorganic hybrid perovskite thin-film devices.
|
|
| 2. |
- Zhuang, Ting, et al.
(författare)
-
SHARPIN stabilizes estrogen receptor a and promotes breast cancer cell proliferation
- 2017
-
Ingår i: Oncotarget. - : Impact Journals, LLC. - 1949-2553. ; 8:44, s. 77137-77151
-
Tidskriftsartikel (refereegranskat)abstract
- Estrogen receptor a is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα protein level by immunohistochemistry. SHARPIN expression level correlates with poor prognosis in ERα positive breast cancer patients. SHARPIN depletion based RNA-sequence data shows that ERα signaling is a potential SHARPIN target. SHARPIN depletion significantly decreases ERα protein level, ERα target genes expression and estrogen response element activity in breast cancer cells, while SHARPIN overexpression could reverse these effects. SHARPIN depletion significantly decreases estrogen stimulated cell proliferation in breast cancer cells, which effect could be further rescued by ERα overexpression. Further mechanistic study reveals that SHARPIN mainly localizes in the cytosol and interacts with ERα both in the cytosol and the nuclear. SHARPIN regulates ERα signaling through protein stability, not through gene expression. SHARPIN stabilizes ERα protein via prohibiting ERα protein poly-ubiquitination. Further study shows that SHARPIN could facilitate the mono-ubiquitinaiton of ERα at K302/303 sites and facilitate ERE luciferase activity. Together, our findings propose a novel ERα modulation mechanism in supporting breast cancer cell growth, in which SHARPIN could be one suitable target for development of novel therapy for ERα positive breast cancer.
|
|
| 3. |
- Bruun, Georg, et al.
(författare)
-
Clock shifts in a Fermi gas interacting with a minority component: A soluble model
- 2010
-
Ingår i: Physical Review A (Atomic, Molecular and Optical Physics). - 1050-2947. ; 81:3
-
Tidskriftsartikel (refereegranskat)abstract
- We consider the absorption spectrum of a Fermi gas mixed with a minority species when majority fermions are transferred to another internal state by an external probe. In the limit when the minority species is much more massive than the majority one, we show that the minority species may be treated as static impurities and the problem can be solved in closed form. The analytical results bring out the importance of vertex corrections, which change qualitatively the nature of the absorption spectrum. It is demonstrated that large line shifts are not associated with resonant interactions in general. We also show that the commonly used ladder approximation fails when the majority component is degenerate for large mass ratios between the minority and majority species and that bubble diagrams, which correspond to the creation of many particle-hole pairs, must be taken into account. We carry out detailed numerical calculations, which confirm the analytical insights, and we point out the connection to shadowing phenomena in nuclear physics.
|
|
| 4. |
- Radamson, Henry H., et al.
(författare)
-
State of the Art and Future Perspectives in Advanced CMOS Technology
- 2020
-
Ingår i: Nanomaterials. - : MDPI AG. - 2079-4991. ; 10:8
-
Forskningsöversikt (refereegranskat)abstract
- The international technology roadmap of semiconductors (ITRS) is approaching the historical end point and we observe that the semiconductor industry is driving complementary metal oxide semiconductor (CMOS) further towards unknown zones. Today's transistors with 3D structure and integrated advanced strain engineering differ radically from the original planar 2D ones due to the scaling down of the gate and source/drain regions according to Moore's law. This article presents a review of new architectures, simulation methods, and process technology for nano-scale transistors on the approach to the end of ITRS technology. The discussions cover innovative methods, challenges and difficulties in device processing, as well as new metrology techniques that may appear in the near future.
|
|
| 5. |
- Yu, Zhenhua, et al.
(författare)
-
Induced interactions in dilute atomic gases and liquid helium mixtures
- 2012
-
Ingår i: Physical Review A. Atomic, Molecular, and Optical Physics. - 1050-2947 .- 1094-1622. ; 85:6, s. 063616-
-
Tidskriftsartikel (refereegranskat)abstract
- In dilute mixtures of two atomic gases, interactions between two minority atoms acquire a contribution due to interaction with the majority component. Using thermodynamic arguments, we derive expressions for this induced interaction for both fermions and bosons for arbitrary strength of the interaction between the two components. Implications of the work for the theory of dilute solutions of He-3 in liquid He-4 are discussed.
|
|
