| 1. |
- Liu, Yehai, et al.
(författare)
-
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma
- 2011
-
Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 131:7, s. 769-773
-
Tidskriftsartikel (refereegranskat)abstract
- Conclusion: Matrix metalloproteinase (MMP)-20 is overexpressed in laryngeal squamous cell carcinoma (LSCC) compared with the adjacent normal laryngeal epithelium and MMP-20 plays a role in lymph node metastasis. Overexpression of MMP-20 may be used as a significant prognostic factor for lymph node metastasis. All the findings indicate that MMP-20 may play a role in the initiation and progression of LSCC. Objective: The MMPs are a gene family of zinc-dependent endopeptidases that have been implicated in tumor invasion and metastasis, and MMP-20 is a new member of the MMP family. The purpose of this study was to investigate whether MMP-20 is overexpressed in human LSCC and, if so, the significance of its overexpression in relation to clinical parameters. Methods: We analyzed 33 cases of LSCC with RT-PCR and 73 cases of LSCC with immunohistochemistry compared with normal laryngeal epithelium. Results: We found that MMP-20 is overexpresssed in LSCC compared with the adjacent normal laryngeal epithelium.
|
|
| 2. |
- Wu, Cary, et al.
(författare)
-
Chinese Citizen Satisfaction with Government Performance during COVID-19
- 2021
-
Ingår i: Journal of Contemporary China. - : Informa UK Limited. - 1067-0564 .- 1469-9400. ; 30:132, s. 930-944
-
Tidskriftsartikel (refereegranskat)abstract
- While foreign pundits have alternatively blamed and praised the Chinese government’s handling of the COVID-19 virus, little is known about how citizens within China understand this performance. This article considers how satisfied Chinese citizens are with their government’s performance during the COVID-19 pandemic. It first considers the impact of authoritarian control, political culture, and/or actual government performance on citizen satisfaction. Then, it tests the consequences of satisfaction and specifically whether citizen satisfaction leads to greater trust. Analyzing data from the first post-COVID survey of its kind (n = 19,816) conducted from April 22 to 28 April 2020, the authors find that Chinese citizens have an overall high level of satisfaction, but that this satisfaction drops with each lower level of government. Further, authoritarian control, political culture, and awareness of government performance all contribute to citizen satisfaction and this in turn, has enhanced public support for the Chinese government.
|
|
