| 1. |
- Huang, Hongyun, et al.
(author)
-
Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)
- 2018
-
In: Cell Transplantation. - : SAGE Publications. - 0963-6897 .- 1555-3892. ; 27:2, s. 310-324
-
Research review (peer-reviewed)abstract
- Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011. The IANR and the Chinese Association of Neurorestoratology (CANR) collaborated to propose the current version "Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)". The IANR council board members and CANR committee members approved this proposal on September 1, 2016, and recommend it to clinical practitioners of cellular therapy. These guidelines include items of cell type nomenclature, cell quality control, minimal suggested cell doses, patient-informed consent, indications for undergoing cell therapy, contraindications for undergoing cell therapy, documentation of procedure and therapy, safety evaluation, efficacy evaluation, policy of repeated treatments, do not charge patients for unproven therapies, basic principles of cell therapy, and publishing responsibility.
|
|
| 2. |
- Zhang, Zhicheng, et al.
(author)
-
The Editorial
- 2023
-
In: Chemistry - An Asian Journal. - : John Wiley & Sons. - 1861-4728 .- 1861-471X. ; 18:6
-
Journal article (other academic/artistic)abstract
- Surface and interface engineering has been considered as a promising strategy to enhance the performance of catalysts towards CO2 reduction. In their editorial to this special collection, guest editors Zhicheng Zhang, Zhen Zhang, Zhenyu Sun, Shaoqi Zhan and Guoxiong Wang provide a brief overview of this field and highlight the state-of-the-art contributions featured in this special collection.
|
|
| 3. |
- Ge, Zhicheng, et al.
(author)
-
Influence of Ru on the thermomechanical fatigue deformation behavior of a single crystal superalloy
- 2022
-
In: International Journal of Fatigue. - : Elsevier. - 0142-1123 .- 1879-3452. ; 156
-
Journal article (peer-reviewed)abstract
- The deformation mechanisms of a single crystal nickel-base superalloy with and without Ru-doped have been investigated under out-of-phase thermomechanical fatigue. The Ru-doped alloy exhibits a thermomechanical fatigue life more than twice as high compared to the Ru-free alloy and a difference in thermomechanical fatigue behavior is also displayed. Microstructure studies by scanning electron microscopy and transmission electron microscopy revealed that the deformation mechanism of the Ru-free alloy in the initial stage is the movement of dislocations in the γ matrix. In the later stage of the thermomechanical fatigue test, large amounts of twins are formed in the material, and a large number of stacking faults and dislocations are sheared into the γ' precipitates. By comparing with the Ru-free alloy, the Ru-doped alloy has a higher matrix strength due to the solid solution strengthening effect of Ru, and is also prone to different deformation mechanisms. For example, the stacking faults are formed in the initial thermomechanical fatigue cycles and remain in the matrix throughout the entire thermomechanical fatigue process. The formation of twins, on the other hand, is suppressed by Ru addition. Such effects are believed to extend the thermomechanical fatigue life effectively.
|
|
| 4. |
- He, Kun, et al.
(author)
-
Experimental study on flame characteristics of double fires in a naturally ventilated tunnel : Flame merging, flame tilt angle and flame height
- 2021
-
In: Tunnelling and Underground Space Technology. - : Elsevier Ltd. - 0886-7798 .- 1878-4364. ; 114
-
Journal article (peer-reviewed)abstract
- A series of fire tests was carried out to investigate the diffusion flame characteristics of double fires generated from separated burners in a naturally ventilated tunnel, considering different heat release rates and fire separation distances. The results show that the flame tilt angle, as well as the horizontal projected flame length, first increases with fire separation distance and then remains constant, but the vertical flame length first decreases and then remains constant, which is different from two fires in free spaces where flames do not tilt when the separation distance is relatively long. This difference is caused by the non-dimensional fire induced air flow velocity in the tunnel, which is mainly related to the tunnel cross-section dimensions and burner radius. Three regions can be identified, i.e. flame vertical merging, plume vertical merging and non-merging with flame tilted. The critical flame merging separation distance, estimated by the flame merging probability, is greater than that of two fires in an open environment due to the fire-induced air flows. The merging flame height is lower than that of a single fire with a same heat release rate. A correlation was proposed to estimate flame height of two fires in a tunnel by the modified non-dimensional heat release rate using an air entrainment perimeter as the characteristic length. This work enhances the understanding of diffusion flame behaviors of double fires in naturally ventilated tunnels.
|
|
| 5. |
- Li, Luhan, et al.
(author)
-
Tailoring charge reconfiguration in dodecahedral Co2P@carbon nanohybrids by triple-doping engineering for promoted reversible oxygen catalysis
- 2022
-
In: Journal of Materials Chemistry A. - : Royal Society of Chemistry. - 2050-7488 .- 2050-7496. ; 10:40, s. 21659-21671
-
Journal article (peer-reviewed)abstract
- Simultaneously tuning the electronic structure of active sites and the microenvironment of the carbon matrix in metal phosphide/carbon nanohybrids is the most effective way to design and develop bi-functional electrocatalysts for electrochemically related energy storage devices. Inspired by this, a robust and advanced N/P co-doped carbon-based dodecahedron catalyst with confined Fe-doped Co2P particles was successfully prepared through a multi-doping engineering strategy. Phytic acid molecules, which were used in the synthesis of the catalyst, not only contribute to the formation of the porous structure, but also act as a phosphorus source to form the corresponding metal phosphide and the P dopant in the carbon matrix. Thanks to the unique composition and structure-dependent merits, the microenvironment of the electrocatalyst was significantly modulated, thus promoting the advantageous local charge rearrangement and smooth mass/charge transfer processes during the oxygen-related electrocatalytic reactions. As a result, the resultant catalyst exhibited significantly enhanced reversible oxygen activity, as evidenced by an ultra-small potential gap of 0.655 V (half-wave potential of 0.895 V for the oxygen reduction reaction; η10 of 320 mV for the oxygen evolution reaction), a remarkable specific capacity of 762 mA h gZn−1, and high voltaic efficiency, exceeding most previous reports. This study provides a new synthetic approach for fabricating highly efficient bi-functional oxygen catalysts and can be handily extended to the synthesis of other heterogeneous electrocatalysts for sustainable energy storage.
|
|
| 6. |
- Li, Zhicheng, et al.
(author)
-
Direct observation of electron-beam-induced nucleation and growth in amorphous GaAs
- 2004
-
In: Materials Science in Semiconductor Processing. - : Elsevier BV. - 1369-8001 .- 1873-4081. ; 7:1-2, s. 19-25
-
Journal article (peer-reviewed)abstract
- In situ observation of the nucleation and growth stimulated by an electron beam in amorphous GaAs was performed using a high-resolution electron microscopy. The results showed that the crystallization was closely related to the current density of the electron beam. Crystallization could not take place when the current density was 50 pA/cm(2), nanocrystals with the random orientation formed under the 74 pA/cm(2) electron beam, large grains and twining structure formed during the crystallization induced by the 93 pA/cm(2) electron beam. Ionization process and electron-beam heating were suggested to be the possible mechanisms for the irradiation-induced crystallization.
|
|
| 7. |
- Li, Zhicheng, et al.
(author)
-
Growth and morphology of beta phase in an Mg-Y-Nd alloy
- 2004
-
In: Materials letters (General ed.). - : Elsevier BV. - 0167-577X .- 1873-4979. ; 58:24, s. 3021-3024
-
Journal article (peer-reviewed)abstract
- The phase precipitated in an Mg-Y-Nd alloy during ageing was studied using electron microscopy. Observations were performed along the orientations paralleling to [0001] and [11 (2) over bar0] zone axes of the matrix. The results showed that the platelike p phase has three variants growing along three <1120> directions of the matrix, the beta phase grew faster along <0001>(alpha) and <1120>(alpha) directions than along the third direction (<1 (1) over bar 00>). The morphology of the beta phases was illustrated according to the analysis of the directional misfit between the beta phase and the matrix.
|
|
| 8. |
- Li, Zhicheng, et al.
(author)
-
Microstructure and PTCR effect of La-doped BaPbO3 ceramics
- 2004
-
In: Journal of materials science. Materials in electronics. - 0957-4522 .- 1573-482X. ; 15:3, s. 183-186
-
Journal article (peer-reviewed)abstract
- La-doped BaPbO3 ceramics were prepared by using BaCO3 and PbO. Electrical properties and microstructure of the ceramics were studied. The results show a thin surface layer with a very low resistivity, and the interior of the ceramics with the characteristics of positive temperature coefficient of resistivity (PTCR). The PTCR behavior was related to the La content. The investigation by scanning electron microscopy and transmission electron microscopy revealed that the low resistivity of the surface layer was due to formation of a nano-size BaPbO3 phase with metallic properties.
|
|
| 9. |
- Nie, Zhicheng, et al.
(author)
-
Reversed charge transfer induced by nickel in Fe-Ni/Mo2C@nitrogen-doped carbon nanobox for promoted reversible oxygen electrocatalysis
- 2024
-
In: Journal of Energy Chemistry. - : Elsevier. - 2095-4956 .- 2096-885X. ; 88, s. 202-212
-
Journal article (peer-reviewed)abstract
- The interaction between metal and support is critical in oxygen catalysis as it governs the charge transfer between these two entities, influences the electronic structures of the supported metal, affects the adsorption energies of reaction intermediates, and ultimately impacts the catalytic performance. In this study, we discovered a unique charge transfer reversal phenomenon in a metal/carbon nanohybrid system. Specifically, electrons were transferred from the metal-based species to N-doped carbon, while the carbon support reciprocally donated electrons to the metal domain upon the introduction of nickel. This led to the exceptional electrocatalytic performances of the resulting Ni-Fe/Mo2C@nitrogen-doped carbon catalyst, with a half-wave potential of 0.91 V towards oxygen reduction reaction (ORR) and a low overpotential of 290 mV at 10 mA cm−2 towards oxygen evolution reaction (OER) under alkaline conditions. Additionally, the Fe-Ni/Mo2C@carbon heterojunction catalyst demonstrated high specific capacity (794 mA h gZn−1) and excellent cycling stability (200 h) in a Zn-air battery. Theoretical calculations revealed that Mo2C effectively inhibited charge transfer from Fe to the support, while secondary doping of Ni induced a charge transfer reversal, resulting in electron accumulation in the Fe-Ni alloy region. This local electronic structure modulation significantly reduced energy barriers in the oxygen catalysis process, enhancing the catalytic efficiency of both ORR and OER. Consequently, our findings underscore the potential of manipulating charge transfer reversal between the metal and support as a promising strategy for developing highly-active and durable bi-functional oxygen electrodes.
|
|
| 10. |
- Nie, Zhicheng, et al.
(author)
-
Tailoring the d-band center by intermetallic charge-transfer manipulation in bimetal alloy nanoparticle confined in N-doped carbon nanobox for efficient rechargeable Zn-air battery
- 2023
-
In: Chemical Engineering Journal. - : Elsevier. - 1385-8947 .- 1873-3212. ; 463
-
Journal article (peer-reviewed)abstract
- In this effort, the electronic-structure modulation strategy through nano-alloying was rationally designed to fabricate Fe-Ni alloy particles embedded in an N-doped carbon nanobox. The as-developed catalyst outperformed the commercialized noble-metal benchmarks with a decent half-wave potential of 0.891 V for ORR and a small overpotential of 325 mV at 10 mA/cm2 for OER both in 0.1 M KOH solution. Beyond that, a highly-efficient regenerative Zn-air battery was also successfully constructed, evidenced by a small potential gap of 0.664 V (between Ej=10 and E1/2), a high specific capacity of 763 mAh/g, a large peak power density of 270 mW/cm2, and robust stability. Ultraviolet photoelectron spectroscopy and theoretical simulation confirmed that the alloying of Ni into Fe could well manipulate the electronic structure, leading to favorable intermetallic charge-transfer and then downshifting the d-band center of Fe adsorption sites, all of which help to significantly lower the reaction barriers of the involved intermediates during the electrocatalytic ORR/OER processes.
|
|
| 11. |
- Nie, Zhicheng, et al.
(author)
-
Vacancy and doping engineering of Ni-based charge-buffer electrode for highly-efficient membrane-free and decoupled hydrogen/oxygen evolution
- 2023
-
In: Journal of Colloid and Interface Science. - : Elsevier. - 0021-9797 .- 1095-7103. ; 642, s. 714-723
-
Journal article (peer-reviewed)abstract
- The realization of the membrane-free two-step water electrolysis is particularly important yet challenging for the low-cost and large-scale supply of hydrogen energy. In this effort, Co-doped Ni(OH)2 nanosheets were successfully anchored onto the nickel foam (NF) substrate through the in-situ growth of metal-organic frame material and the subsequent alkali-etching technique. Using the well-regulated Co-doping Ni(OH)2@NF electrodes as a charge mediator, electrochemical hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) were decoupled on time scales, thus affording a membrane-free two-step route for H2 and O2 productions. In this architecture, the first HER process on the cathode could be maintained for 1300 s at a current of 100 mA, while the corresponding Ni(OH)2 charge mediator was simultaneously oxidized to NiOOH, with a decent cell voltage of 1.542 V. The subsequent OER process involved a reduction/regeneration of Ni(OH)2 (from NiOOH to Ni(OH)2) and an anodic O2-production, with an operating voltage of 0.291 V. Moreover, the Ni-Zn battery assembled through the combination of NiOOH and Zn sheet could replace the second step of OER to achieve the coupling of continuous H2-production and battery discharge, thus also providing a new way for hydrogen production without an external power supply. Experiment and theoretical calculations have shown that the cobalt-doping not only improved the conductivity of the charge-buffer electrode, but also shifted its redox potential cathodically and boosted the adsorption affinity of the buffer medium to OH– ions, both contributing to promoted HER and OER activity. Therefore, this decoupled water electrolysis device affords a promising pathway to support the efficient conversion of renewables to hydrogen.
|
|
| 12. |
- Tong, Chengzhuo, et al.
(author)
-
Mapping microscale PM2.5 distribution on walkable roads in a high-density city
- 2021
-
In: IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing. - 1939-1404. ; 14, s. 6855-6870
-
Journal article (peer-reviewed)abstract
- Monitoring pollution of PM2.5 on walkable roads is important for resident health in high-density cities. Due to the spatiotemporal resolution limitations of Aerosol Optical Depth (AOD) observation, fixed-point monitoring, or traditional mobile measurement instruments, the microscale PM2.5 distribution in the walking environment cannot be fully estimated at the fine scale. In this study, by the integration of mobile measurement data, OpenStreetMap (OSM) data, Landsat images, and other multi-source data in land-use regression (LUR) models, a novel framework is proposed to estimate and map PM2.5 distribution in a typical microscale walkable environment of the high-density city Hong Kong. First, the PM2.5 data on the typical walking paths were collected by the handheld mobile measuring instruments, to be selected as the dependent variables. Second, Geographic prediction factors calculated by Google Street View, OpenStreetMap (OSM) data, Landsat images, and other multi-source data were further selected as independent variables. Then, these dependent and independent variables were put into the LUR models to estimate the PM2.5 concentration on sidewalks, footbridges, and footpaths in the microscale walkable environment. The proposed models showed high performance relative to those in similar studies (adj R2, 0.593 to 0.615 [sidewalks]; 0.641 to 0.682 [footpaths]; 0.783 to 0.797 [footbridges]). This study is beneficial for mapping PM2.5 concentration in the microscale walking environment and the identification of hot spots of air pollution, thereby helping people avoid the PM2.5 hotspots and indicating a healthier walking path.
|
|
| 13. |
- Ye, Ying, et al.
(author)
-
Simultaneously promoting charge and mass transports in carved particle-in-box nanoreactor for rechargeable Zn-air battery
- 2022
-
In: Chemical Engineering Journal. - : Elsevier. - 1385-8947 .- 1873-3212. ; 446
-
Journal article (peer-reviewed)abstract
- Fundamental understanding of fabricating promoted bi-functional electrocatalyst to achieve fast charge-transfer and smooth mass-transport in oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) through the rational management of catalyst composition and ingenious design of nanostructure is highly desired but still a formidable challenge. Herein, an advanced carved particle-in-box nanoreactor, composed of small Fe-Co-Ni tri-metallic alloy nanoparticles confined in porous nitrogen-doped carbon nanocage, was developed through a spatially-confined pyrolysis strategy. Tri-metal alloy could optimize the electronic structure of the catalyst, thus inducing the charge redistribution, and then regulating the adsorption and desorption energy barriers of intermediates in electrochemical reactions. Unique nano-hole design provided convenient and efficient channels for mass transfer during ORR and OER processes. Thanks to these attributes, the hybrid electrocatalyst delivered decent reversible oxygen catalytic activities, evidenced by a high half-wave potential of 0.850 V towards ORR and a low overpotential of 355 mV at 10 mA/cm2 for OER both in alkaline electrolyte. As a proof-of-concept, this as-developed carved particle-in-box nanoreactor enabled the assembled Zn-air battery to deliver a narrow potential gap of 0.735 V, a decent power density of 315 mW/cm2, a notable specific capacity of 754 mAh/gZn and excellent durability up to 165 h of continuous charge and discharge operations, thus implying the potential applications of this sophisticated catalyst model for promising energy conversion.
|
|
| 14. |
- Zhang, Guiling, et al.
(author)
-
Understanding the influence of alendronate on the morphology and phase transformation of apatitic precursor nanocrystals
- 2012
-
In: Journal of Inorganic Biochemistry. - : Elsevier BV. - 0162-0134 .- 1873-3344. ; 113, s. 1-8
-
Journal article (peer-reviewed)abstract
- Bisphosphonates (BPs) are a class of synthetic pyrophosphate analogs that can prevent the loss of bone mass, given orally to treat postmenopuasal osteoporosis. It is not clear yet if the benefits of BPs include the possibility of affecting bone apatitic precursors transition for bone consolidation except for encouraging osteoclasts to undergo apoptosis. Furthermore, the complexity of the in vivo system makes it difficult to isolate and study such extracellular topographical cues that trigger bone turnover response. Herein, we proposed a wet-chemical approach employing alendronate sodium (AS) as a guide of hydroxyapatite (HA) precursor growth and conversion which was initiated from the nucleantion of octacalcium phosphate (OCP) in a cell membrane-mimicking surfactant micelle aqueous system. The nanocrystal clusters of dicalcium phosphate dihydrate (DCPD) and OCP nanocryatals were readily precipitated within a relatively narrow AS concentration range (2-8 mu M). However, such low concentrations of AS seemed to stabilize the more acidic phases, and to delay the transformation into HA, to an extent which increased on increasing AS concentration. In contrast, at a slight higher concentrations (16-32 mu M), AS promoted HA precipitation after ageing for 1 h. It was found that the effect of AS on the phase selectivity of apatitic precursors was concentration-dependent within a prolonged ageing time stage (0.5-168 h). The AS-assisted reactions in vitro offer an expedient way to understand the underlying implementarity between bone and BPs for bone consolidation, and to improve our understanding of benefit of BP dosages on bone turnover and trauma healing.
|
|
