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- Li, Xinyu, et al.
(författare)
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Biodegradable MOFilters for Effective Air Filtration and Sterilization by Coupling MOF Functionalization and Mechanical Polarization of Fibrous Poly(lactic acid)
- 2023
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Ingår i: ACS Applied Materials and Interfaces. - : American Chemical Society (ACS). - 1944-8244 .- 1944-8252. ; 15:22, s. 26812-26823
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Tidskriftsartikel (refereegranskat)abstract
- High-performance air filtration materials are importantfor addressingthe airborne pollutants. Herein, we propose an unprecedented accessto biodegradable poly-(lactic acid) (PLA)-based MOFilters with excellentfiltering performance and antibacterial activity. The fabricationinvolved a stepwise in situ growth of zeolitic imidazolate framework-8(ZIF-8) crystals at the surface of microfibrous PLA membranes, followedby mechanical polarization under high pressure and low temperature(5 MPa, 40 degrees C) to trigger the ordered alignment of dipoles inPLA chains and ZIF-8. The unique structural features allowed thesePLA-based MOFilters to achieve an exceptional combination of excellenttensile properties, high dielectric constant (up to 2.4 F/m), andenhanced surface potential as high as 4 kV. Arising from the remarkablesurface activity and electrostatic adsorption effect, a significantincrease (from over 12% to nearly 20%) in PM0.3 filtrationefficiency was observed for the PLA-based MOFilters compared to thatof pure PLA counterparts, with weak relation to the airflow velocities(10-85 L/min). Moreover, the air resistance was controlledat a considerably low level for all the MOFilters, that is, below183 Pa even at 85 L/min. It is worth noting that distinct antibacterialproperties were achieved for the MOFilters, as illustrated by theinhibitive rates of 87 and 100% against Escherichiacoli and Staphylococcus aureus, respectively. The proposed concept of PLA-based MOFilters offersunprecedented multifunction integration, which may fuel the developmentof biodegradable versatile filters with high capturing and antibacterialperformances yet desirable manufacturing feasibility.
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| 2. |
- Li, Yifei, et al.
(författare)
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Can Nup88 expression be associated with atypical endometrial hyperplasia and endometrial cancer? A preliminary study
- 2016
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Ingår i: Pathology, Research and Practice. - : ELSEVIER GMBH, URBAN & FISCHER VERLAG. - 0344-0338 .- 1618-0631. ; 212:4, s. 274-278
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Tidskriftsartikel (refereegranskat)abstract
- Background: Nup88 is overexpressed in a number of types of carcinomas and is associated with myometrial invasion, but its exact expression pattern in endometrial cancer and premalignant lesions is unknown. Aims: To evaluate the role of Nup88 in endometrial cancers and atypical endometrial hyperplasia and its clinicopathological significance. Methods: Nup88 expression was examined by immunohistochemistry in samples from 104 endometrial cancers, 21 atypical endometrial hyperplasia lesions, and 40 normal endometria. All samples were from patients who underwent surgery at the First Hospital of Hebei Medical University (Shijiazhuang, China) between April 2006 and December 2009. Nup88 expression was compared between the groups and associations were assessed between Nup88 and clinicopathological characteristics of the subjects. Results: Nup88 expression in cancer (76% of samples) and atypical hyperplasia (91%) was significantly higher compared to normal endometrium (33%, both P < 0.001), but there was no significant difference between endometrial cancer and atypical hyperplasia (P = 0.237). The expression of Nup88 increased significantly with increasing exposure time to estrogen (P = 0.033). Conclusions: Nup88 may be related to the occurrence of endometrial cancers and premalignant lesions. Nup88 might be a useful biomarker for pre-malignant lesions and early-stage endometrial cancer. (C) 2016 Elsevier GmbH. All rights reserved.
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