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Träfflista för sökning "L773:1873 3344 OR L773:1873 3344 OR L773:0162 0134 srt2:(1987-1989)"

Search: L773:1873 3344 OR L773:1873 3344 OR L773:0162 0134 > (1987-1989)

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  • Dyrssen, David, et al. (author)
  • Complexation of aluminum with DNA.
  • 1987
  • In: Journal of inorganic biochemistry. - 0162-0134 .- 1873-3344. ; 29:1, s. 67-75
  • Journal article (peer-reviewed)abstract
    • The extent of complexation of aluminum(III) with DNA (Calf thymus, Sigma type I) was estimated by means of two experimental techniques: potentiometric titration with a fluoride selective indicator electrode and dialysis followed by aluminum determination by graphite furnace AAS. Both types of experiments indicate that aluminum(III) is bound to DNA. The data are treated by assuming an ion exchange reaction with the phosphate diester groups. Using Rt to denote the concentration of these groups the values of log [AlMn-3R]/(Rt-3[AlMn-3R])[Al3+] decrease from approx. 7.6 to 5.6 when the concentration of sodium chloride is increased from 1 to 100 mM. In the pH range 4.5-5.5 the ion exchange constant increases approximately 0.5 log units. Dialysis gives lower values for the complex formation constant than potentiometry.
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  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Nyberg, Eva, 1958 (1)
Wedborg, Margareta, ... (1)
Haraldsson, Conny (1)
Dyrssen, David (1)
University
University of Gothenburg (1)
Chalmers University of Technology (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
1987 (1)

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