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Träfflista för sökning "WFRF:(Åkerlund Anna) "

Search: WFRF:(Åkerlund Anna)

  • Result 1-10 of 37
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  • Ekwall, Daniel, 1974-, et al. (author)
  • The moderating role of transport chain location in cargo theft risk
  • 2020
  • In: The TQM Journal. - : Emerald Group Holdings Ltd.. - 1754-2731 .- 1754-274X. ; 32:5, s. 1003-1019
  • Journal article (peer-reviewed)abstract
    • Purpose: The purpose of this paper is to explore cargo theft risk and security for different product types at different locations along a transport chain. Design/methodology/approach: This study is based on a system-theoretical approach. The research method is deductive, as the analysis is based on secondary data and results from a questionnaire. The results are analysed based on supply chain risk management (SCRM) theories. Findings: Due to substantial interaction effects, the type of product and transport chain location must be considered to determine the correct level of security. Specifically, the product type is more significant, since the general cargo theft risk is higher. Furthermore, the transport industry has three perspectives on security responses to cargo theft, namely, demanded, needed and actual security, which differ depending on the product type and transport chain location. Research limitations/implications: This database is structured according to the global Transported Asset Protection Association organisational structure, which implies that there are three main databases: Europe, Middle East and Africa, Americas, and Asia-Pacific. Practical implications: This study has both research and practical implications, as it examines security within freight transport from three perspectives, linked to general cargo theft risk and goods owners’ requirements. Originality/value: This study addresses the contemporary SCRM problem of cargo theft using actual crime statistics and the industry understanding of required generic security levels. © 2019, Emerald Publishing Limited.
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  • Boström, Anders E, 1951 (author)
  • Scattering of acoustic waves by a layered elastic obstacle in a fluid - an improved null field appraoch
  • 1984
  • In: Journal of the Acoustical Society of America. - 1520-8524 .- 0001-4966. ; 76, s. 588-593
  • Journal article (peer-reviewed)abstract
    • Scattering by a layered elastic obstacle submerged in a fluid is considered. The null field approach (T-matrix method) is used, but the method is modified so that all surface fields can be expanded in spherical harmonics. The resulting method is then compared with the conventional null field approach (which uses expansions in regular wavefunctions), and it is concluded that the present method is better in general. It is, however, doubtful if the null field approach is applicable to cases where there is no sphere that circumscribes the core and inscribes the outer surface. Some numerical results are given for a layered spheroid and superspheroid.
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  • Eskilsson, Lena (author)
  • Fat
  • 2005
  • In: Svenska Dagbladet. ; :2005-06-02
  • Journal article (other academic/artistic)
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8.
  • Follwaczny, Philipp, et al. (author)
  • Pumilio2-deficient mice show a predisposition for epilepsy.
  • 2017
  • In: Disease Models and Mechanisms. - : The Company of Biologists. - 1754-8403 .- 1754-8411. ; 10:11, s. 1333-1342
  • Journal article (peer-reviewed)abstract
    • Epilepsy is a neurological disease that is caused by abnormal hypersynchronous activities of neuronal ensembles leading to recurrent and spontaneous seizures in human patients. Enhanced neuronal excitability and a high level of synchrony between neurons seem to trigger these spontaneous seizures. The molecular mechanisms, however, regarding the development of neuronal hyperexcitability and maintenance of epilepsy are still poorly understood. Here, we show that pumilio RNA-binding family member 2 (Pumilio2; Pum2) plays a role in the regulation of excitability in hippocampal neurons of weaned and 5-month-old male mice. Almost complete deficiency of Pum2 in adult Pum2 gene-trap mice (Pum2 GT) causes misregulation of genes involved in neuronal excitability control. Interestingly, this finding is accompanied by the development of spontaneous epileptic seizures in Pum2 GT mice. Furthermore, we detect an age-dependent increase in Scn1a (Nav1.1) and Scn8a (Nav1.6) mRNA levels together with a decrease in Scn2a (Nav1.2) transcript levels in weaned Pum2 GT that is absent in older mice. Moreover, field recordings of CA1 pyramidal neurons show a tendency towards a reduced paired-pulse inhibition after stimulation of the Schaffer-collateral-commissural pathway in Pum2 GT mice, indicating a predisposition to the development of spontaneous seizures at later stages. With the onset of spontaneous seizures at the age of 5 months, we detect increased protein levels of Nav1.1 and Nav1.2 as well as decreased protein levels of Nav1.6 in those mice. In addition, GABA receptor subunit alpha-2 (Gabra2) mRNA levels are increased in weaned and adult mice. Furthermore, we observe an enhanced GABRA2 protein level in the dendritic field of the CA1 subregion in the Pum2 GT hippocampus. We conclude that altered expression levels of known epileptic risk factors such as Nav1.1, Nav1.2, Nav1.6 and GABRA2 result in enhanced seizure susceptibility and manifestation of epilepsy in the hippocampus. Thus, our results argue for a role of Pum2 in epileptogenesis and the maintenance of epilepsy.
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  • Result 1-10 of 37
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