| 1. |
- Pinheiro, R., et al.
(author)
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A world full of mergers : The nordic countries in a global context
- 2016
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In: Higher Education Dynamics. - Cham : Springer Science and Business Media B.V.. ; , s. 3-25
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Book chapter (peer-reviewed)abstract
- In this introductory chapter to the volume, the editors present the findings from a literature review undertaken on the topic, and link classical organizational perspectives to the study of merger processes involving higher education institutions. The chapter provides a brief overview of developments across Nordic higher education by referring to Burton Clark’s famous ‘triangle of coordination’. The authors conclude by sketching out the rationale and aim of the comparative study, the ways in which the volume is organized and by providing a short summary of its individual contributions.
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| 2. |
- Abe, H., et al.
(author)
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Gamma-ray observations of MAXI J1820+070 during the 2018 outburst
- 2022
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In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press. - 0035-8711 .- 1365-2966. ; 517:4, s. 4736-4751
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Journal article (peer-reviewed)abstract
- MAXIJ1820+070 is a low-mass X-ray binary with a black hole (BH) as a compact object. This binary underwent an exceptionally bright X-ray outburst from 2018 March to October, showing evidence of a non-thermal particle population through its radio emission during this whole period. The combined results of 59.5 h of observations of the MAXI J1820+070 outburst with the H.E.S.S., MAGIC and VERITAS experiments at energies above 200 GeV are presented, together with Fermi-LAT data between 0.1 and 500 GeV, and multiwavelength observations from radio to X-rays. Gamma-ray emission is not detected from MAXI J1820+070, but the obtained upper limits and the multiwavelength data allow us to put meaningful constraints on the source properties under reasonable assumptions regarding the non-thermal particle population and the jet synchrotron spectrum. In particular, it is possible to show that, if a high-energy (HE) gamma-ray emitting region is present during the hard state of the source, its predicted flux should be at most a factor of 20 below the obtained Fermi-LAT upper limits, and closer to them for magnetic fields significantly below equipartition. During the state transitions, under the plausible assumption that electrons are accelerated up to similar to 500 GeV, the multiwavelength data and the gamma-ray upper limits lead consistently to the conclusion that a potential HE and very-HE gamma-ray emitting region should be located at a distance from the BH ranging between 10(11) and 10(13) cm. Similar outbursts from low-mass X-ray binaries might be detectable in the near future with upcoming instruments such as CTA.
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| 3. |
- Verdelho, A., et al.
(author)
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White matter changes and diabetes predict cognitive decline in the elderly The LADIS Study
- 2010
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In: Neurology. - 0028-3878 .- 1526-632X. ; 75:2, s. 160-167
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Journal article (peer-reviewed)abstract
- OBJECTIVE: We aimed to study if age-related white matter changes (WMC) and vascular risk factors were predictors of cognitive decline in elderly subjects with WMC living independently. METHODS: The Leukoaraiosis and Disability prospective multinational European study (LADIS) evaluates the impact of WMC on the transition of independent elderly subjects into disability. Independent elderly were enrolled due to the presence of WMC. Subjects were evaluated yearly during 3 years with a comprehensive clinical protocol and a neuropsychological battery. Additionally, dementia, subtypes of dementia, and cognitive decline without dementia were classified according to usual clinical criteria. MRI was performed at entry and at the end of the study. RESULTS: A total of 639 subjects were included (74.1 +/- 5 years, 55% women, 9.6 +/- 3.8 years of schooling). At end of follow-up, 90 patients had dementia and 147 had cognitive impairment no dementia. Using Cox regression analysis, WMC severity independently predicted cognitive decline (dementia and not dementia), independently of age, education, and medial temporal atrophy (MTA). Diabetes at baseline was the only vascular risk factor that independently predicted cognitive decline during follow-up, controlling for age, education, WMC severity, and temporal atrophy. Considering subtypes of dementia, Alzheimer disease (AD) was predicted only by MTA, while vascular dementia was predicted by previous stroke, WMC severity, and MTA. CONCLUSION: WMC severity and diabetes are independent predictors of cognitive decline in an initially nondisabled elderly population. Vascular dementia is predicted by previous stroke and WMC, while AD is predicted only by MTA.
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| 4. |
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| 5. |
- Schweda, Elke K. H., et al.
(author)
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Profiling structural elements of short-chain lipopolysaccharide of non-typeable Haemophilus influenzae
- 2008
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In: Innate Immunity. - : SAGE Publications. - 1753-4259 .- 1753-4267. ; 14:4, s. 199-211
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Journal article (peer-reviewed)abstract
- Lipopolysaccharide (LPS) is a major Virulence determinant of the human bacterial pathogen Hoemophilus influenzae. A characteristic feature of H. influenzae LPS is the extensive intra- and inter-strain heterogeneity of glycoform structure which is key to the role of the molecule in both commensal and disease-causing behaviour of the bacterium. The chemical composition of non-typeable Haemophilus influenzae (NTHi) LPS is hi-lily diverse. It contains a number of different monosaccharides (Neu5Ac, L-glycero-D-manno heptose, D-glycero-D-manno heptose, Kdo, D-Glc, D-Gal, D-GlcNAc, D-GaINAc) and non-carbohydrate substituents. Prominent non-carbohydrate components are O-acetyl groups, glycine and phosphates. We now know that sialic acid (N-acetylneuraminic acid or Neu5Ac) and certain oligosaccharide extensions are important in the pathogenesis of NTHi: however, the biological implications for many of the various features are Still unknown. Electrospray ionization mass spectrometry ill combination with separation techniques like CE and HPLC is an indispensable tool in profiling glycoform populations ill heterogeneous LPS samples. Mass Spectrometry is characterized by its extreme sensitivity. Trace amounts of glycoforms expressing important Virulence determinants can be detected and characterized on minute amounts of material. The present review focuses oil LPS structures and mass spectrometric methods which enable us to profile these in complex mixtures.
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| 6. |
- Candréus, Cecilia, 1973-
(author)
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Dealing with Mobility : Guilds and Tramping Journeymen in Seventeenth-Century Scandinavia
- 2024
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In: Cultural and social history. - : Routledge. - 1478-0038 .- 1478-0046. ; 21:2, s. 163-184
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Journal article (peer-reviewed)abstract
- The aim of this paper is to discuss the mobility of skilled labour within small and specialised guilds in peripheral Europe during the mid-seventeenth century. Based on archival records for passementerie makers and embroiderers in Stockholm, Sweden and Copenhagen, Denmark, the paper highlights conflicts brought on by labour mobility. What can these conflicts tell us about the situation within two small and specialised trades in Scandinavia, and how were they handled? The study examines examples of the actual implementation of both regulations and traditions associated with the crafts. This illuminates historical strategies for human resource management as well as economic relations between Scandinavia and the Continent. The results suggest a balancing act of negotiations between the needs of journeymen and masters respectively, paired with a pronounced need to align with their German counterparts. It also becomes clear that conditions differed between Stockholm and Copenhagen. Not only was the number of native artisans higher within the Danish guilds concerned, there was also substantial re-growth by apprenticeship. In contrast, Sweden was heavily dependent on immigration of skilled labour.
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| 7. |
- Fernandes, Sofia, et al.
(author)
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NORMO : A new method for estimating the number of components in CP tensor decomposition
- 2020
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In: Engineering applications of artificial intelligence. - Oxford : Elsevier. - 0952-1976 .- 1873-6769. ; 96
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Journal article (peer-reviewed)abstract
- Tensor decompositions are multi-way analysis tools which have been successfully applied in a wide range of different fields. However, there are still challenges that remain few explored, namely the following: when applying tensor decomposition techniques, what should we expect from the result? How can we evaluate its quality? It is expected that, when the number of components is suitable, then few redundancy is observed in the decomposition result. Based on this assumption, we propose a new method, NORMO, which aims at estimating the number of components in CANDECOMP/PARAFAC (CP) decomposition so that no redundancy is observed in the result. To the best of our knowledge, this work encompasses the first attempt to tackle such problem. According to our experiments, the number of non-redundant components estimated by NORMO is among the most accurate estimates of the true CP number of components in both synthetic and real-world tensor datasets (thus validating the rationale guiding our method). Moreover, NORMO is more efficient than most of its competitors. Additionally, our method can be used to discover multi-levels of granularity in the patterns discovered. © 2020 Elsevier Ltd
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| 8. |
- Knuts, Eva, 1966
(author)
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Forskaren i provrummet
- 2005
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In: Kulturella perspektiv. - 1102-7908. ; :3
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Journal article (peer-reviewed)
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| 9. |
- Biscari, Giuseppina, et al.
(author)
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Antibacterial Broad-Spectrum Dendritic/Gellan Gum Hybrid Hydrogels with Rapid Shape-Forming and Self-Healing for Wound Healing Application
- 2023
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In: Macromolecular Bioscience. - : Wiley. - 1616-5187 .- 1616-5195.
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Journal article (peer-reviewed)abstract
- Treating wound infections is a difficult task ever since pathogenic bacteria started to develop resistance to common antibiotics. The present study develops hybrid hydrogels based on the formation of a polyelectrolyte complex between the anionic charges of dopamine-functionalized Gellan Gum (GG-DA) and the cationic moieties of the TMP-G2-alanine dendrimer. The hydrogels thus obtained can be doubly crosslinked with CaCl2, obtaining solid hydrogels. Or, by oxidizing dopamine to GG-DA, possibly causing further interactions such as Schiff Base and Michael addition to take place, hydrogels called injectables can be obtained. The latter have shear-thinning and self-healing properties (efficiency up to 100%). Human dermal fibroblasts (HDF), human epidermal keratinocytes (HaCaT), and mouse monocyte cells (RAW 264.7), after incubation with hydrogels, in most cases show cell viability up to 100%. Hydrogels exhibit adhesive behavior on various substrates, including porcine skin. At the same time, the dendrimer serves to crosslink the hydrogels and endows them with excellent broad-spectrum microbial eradication activity within four hours, evaluated using Staphylococcus aureus 2569 and Escherichia coli 178. Using the same GG-DA/TMP-G2-alanine ratios hybrid hydrogels with tunable properties and potential for wound dressing applications can be produced.
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| 10. |
- Del Ferraro, Gino
(author)
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Equilibrium and Dynamics on Complex Networkds
- 2016
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Doctoral thesis (other academic/artistic)abstract
- Complex networks are an important class of models used to describe the behaviour of a very broad category of systems which appear in different fields of science ranging from physics, biology and statistics to computer science and other disciplines. This set of models includes spin systems on a graph, neural networks, decision networks, spreading disease, financial trade, social networks and all systems which can be represented as interacting agents on some sort of graph architecture.In this thesis, by using the theoretical framework of statistical mechanics, the equilibrium and the dynamical behaviour of such systems is studied.For the equilibrium case, after presenting the region graph free energy approximation, the Survey Propagation method, previously used to investi- gate the low temperature phase of complex systems on tree-like topologies, is extended to the case of loopy graph architectures.For time-dependent behaviour, both discrete-time and continuous-time dynamics are considered. It is shown how to extend the cavity method ap- proach from a tool used to study equilibrium properties of complex systems to the discrete-time dynamical scenario. A closure scheme of the dynamic message-passing equation based on a Markovian approximations is presented. This allows to estimate non-equilibrium marginals of spin models on a graph with reversible dynamics. As an alternative to this approach, an extension of region graph variational free energy approximations to the non-equilibrium case is also presented. Non-equilibrium functionals that, when minimized with constraints, lead to approximate equations for out-of-equilibrium marginals of general spin models are introduced and discussed.For the continuous-time dynamics a novel approach that extends the cav- ity method also to this case is discussed. The main result of this part is a Cavity Master Equation which, together with an approximate version of the Master Equation, constitutes a closure scheme to estimate non-equilibrium marginals of continuous-time spin models. The investigation of dynamics of spin systems is concluded by applying a quasi-equilibrium approach to a sim- ple case. A way to test self-consistently the assumptions of the method as well as its limits is discussed.In the final part of the thesis, analogies and differences between the graph- ical model approaches discussed in the manuscript and causal analysis in statistics are presented.
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