SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Marino Jacopo) ;pers:(Nilsson Ola B.)"

Search: WFRF:(Marino Jacopo) > Nilsson Ola B.

  • Result 1-1 of 1
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • Nilsson, Ola B., et al. (author)
  • Cotranslational Protein Folding inside the Ribosome Exit Tunnel
  • 2015
  • In: Cell Reports. - : Elsevier BV. - 2211-1247. ; 12:10, s. 1533-1540
  • Journal article (peer-reviewed)abstract
    • At what point during translation do proteins fold? It is well established that proteins can fold cotranslationally outside the ribosome exit tunnel, whereas studies of folding inside the exit tunnel have so far detected only the formation of helical secondary structure and collapsed or partially structured folding intermediates. Here, using a combination of co-translational nascent chain force measurements, inter-subunit fluorescence resonance energy transfer studies on single translating ribosomes, molecular dynamics simulations, and cryoelectron microscopy, we show that a small zinc-finger domain protein can fold deep inside the vestibule of the ribosome exit tunnel. Thus, for small protein domains, the ribosome itself can provide the kind of sheltered folding environment that chaperones provide for larger proteins.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-1 of 1

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view