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- Gharizadeh, Baback, et al.
(författare)
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Viral and microbial genotyping by a combination of multiplex competitive hybridization and specific extension followed by hybridization to generic tag arrays
- 2003
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Ingår i: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 31:22, s. e146-
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Tidskriftsartikel (refereegranskat)abstract
- Detection and identification of microbial pathogens are important for disease diagnosis, treatment and prophylaxis measurements. By introducing an innovative technique, we show a robust, reliable and accurate microarray-based method for identification of microbial pathogens. The technique utilizes a unique combination of multiplex competitive hybridization, which enhances hybridization accuracy of oligonucleotides to the specific target, and apyrase-mediated allele-specific extension, which improves specific extension. As a model system, different clinically relevant human papillomaviruses were selected for this study. The method generated accurate results and proves to be promising for specific and correct microbial and viral typing.
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| 3. |
- Arrowsmith, C. D., et al.
(författare)
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Laboratory realization of relativistic pair-plasma beams
- 2024
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- Relativistic electron-positron plasmas are ubiquitous in extreme astrophysical environments such as black-hole and neutron-star magnetospheres, where accretion-powered jets and pulsar winds are expected to be enriched with electron-positron pairs. Their role in the dynamics of such environments is in many cases believed to be fundamental, but their behavior differs significantly from typical electron-ion plasmas due to the matter-antimatter symmetry of the charged components. So far, our experimental inability to produce large yields of positrons in quasi-neutral beams has restricted the understanding of electron-positron pair plasmas to simple numerical and analytical studies, which are rather limited. We present the first experimental results confirming the generation of high-density, quasi-neutral, relativistic electron-positron pair beams using the 440 GeV/c beam at CERN’s Super Proton Synchrotron (SPS) accelerator. Monte Carlo simulations agree well with the experimental data and show that the characteristic scales necessary for collective plasma behavior, such as the Debye length and the collisionless skin depth, are exceeded by the measured size of the produced pair beams. Our work opens up the possibility of directly probing the microphysics of pair plasmas beyond quasi-linear evolution into regimes that are challenging to simulate or measure via astronomical observations.
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| 6. |
- Lemeshko, Oleksandr, et al.
(författare)
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Complex Investigation of the Compromise Probability Behavior in Traffic Engineering Oriented Secure Routing Model in Software-Defined Networks
- 2022
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Ingår i: Lecture Notes in Electrical Engineering. - Cham : Springer. - 9783030924355 ; , s. 145-160
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Konferensbidrag (refereegranskat)abstract
- In the work, the complex investigation and analysis results of the compromise probability behavior in Traffic Engineering oriented secure routing model in software-defined networks have been presented. Within the framework of the study, the classical flow-based model based on load balancing in accordance with the principles of the Traffic Engineering concept was improved and supplemented with conditions that allow considering the network security parameters in the process of obtaining a routing solution. In this way it was obtained the secure traffic engineering routing model, the novelty of which lies in the modified conditions of load balancing considering such network characteristics as topology, features of the traffic transmitted, as well as links bandwidth and probabilities of their compromising. The use of such a model makes it possible to reduce the overload of network links with a high value of compromise probability, while more traffic will be transmitted over secure links without causing overload. Power and exponential forms of functional dependence of weighting coefficients on the link compromise probability have been used for comparison during obtaining the secure-based routing solutions. The secure traffic engineering routing flow-based model under investigation is proposed to use in a software-defined network data plane. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
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