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  • Thoresen, Christian, et al. (author)
  • Arousal Modulates Activity in the Medial Temporal Lobe during a Short-Term Relational Memory Task.
  • 2011
  • In: Frontiers in human neuroscience. - 1662-5161. ; 5, s. 177-
  • Journal article (peer-reviewed)abstract
    • This study investigated the effect of arousal on short-term relational memory and its underlying cortical network. Seventeen healthy participants performed a picture by location, short-term relational memory task using emotional pictures. Functional magnetic resonance imaging was used to measure the blood-oxygenation-level dependent signal relative to task. Subjects' own ratings of the pictures were used to obtain subjective arousal ratings. Subjective arousal was found to have a dose-dependent effect on activations in the prefrontal cortex, amygdala, hippocampus, and in higher order visual areas. Serial position analyses showed that high arousal trials produced a stronger primacy and recency effect than low arousal trials. The results indicate that short-term relational memory may be facilitated by arousal and that this may be modulated by a dose-response function in arousal-driven neuronal regions.
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