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  • Caraballo, Rémi, et al. (author)
  • Direct STD NMR Identification of beta-Galactosidase Inhibitors from a Virtual Dynamic Hemithioacetal System
  • 2010
  • In: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 49:3, s. 589-593
  • Journal article (peer-reviewed)abstract
    •  The formation of a dynamic hemithioacetal system and its application toward the discovery of ß-galactosidase inhibitors were successfully investigated. The designed dynamic system, which has a virtual character in neutral aqueous media, was subjected to a direct in situ identification of the best inhibitors by 1H STD NMR spectroscopy (ONPC : o-nitrophenyl-β-galactopyranoside).
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Ramström, Olof (1)
Dong, Hai (1)
Jiménez-Barbero, Jes ... (1)
Caraballo, Remi (1)
Ribeiro, Joao P. (1)
University
Royal Institute of Technology (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2010 (1)

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