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  • Bergström, Joakim H., 1977, et al. (author)
  • Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16
  • 2016
  • In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 113:48, s. 13833-13838
  • Journal article (peer-reviewed)abstract
    • The small lectin-like protein ZG16 (zymogen granulae protein 16) aggregates bacteria and by that works together with the inner colon mucus layer to maintain bacteria at a safe distance from the epithelial cell surface. In the absence of Zg16, more bacteria penetrate the epithelium, enter the regional lymph nodes and spleen, trigger the immune system, and cause abdominal fat pad mass increase. ZG16 is important for a safe normal host-bacteria symbiosis as it does not kill commensal bacteria, but limit bacterial translocation into the host.
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Type of publication
journal article (1)
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peer-reviewed (1)
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Bergström, Joakim H. ... (1)
1975 (1)
1971 (1)
1951 (1)
University
University of Gothenburg (1)
Umeå University (1)
Language
English (1)
Year
2016 (1)

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