SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "id:"swepub:oai:DiVA.org:uu-104372" "

Search: id:"swepub:oai:DiVA.org:uu-104372"

  • Result 1-1 of 1
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • Heldin, Carl-Henrik, et al. (author)
  • Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition
  • 2009
  • In: Current Opinion in Cell Biology. - : Elsevier Ltd.. - 0955-0674 .- 1879-0410. ; 21:2, s. 166-176
  • Research review (peer-reviewed)abstract
    • Members of the transforming growth factor-beta (TGF-beta) family have important roles during embryogenesis, as well as in the control of tissue homeostasis in the adult. They exert their cellular effects via binding to serine/threonine kinase receptors. Members of the Smad family of transcription factors are important intracellular messengers, and recent studies have shown that the ubiquitin ligase TRAF6 mediates other specific signals. TGF-beta signaling is tightly controlled by post-translational modifications, which regulate the activity, stability, and subcellular localization of the signaling components. The aim of this review is to summarize some of the recent findings on the mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-1 of 1
Type of publication
research review (1)
Type of content
peer-reviewed (1)
Author/Editor
Heldin, Carl-Henrik (1)
Moustakas, Aristidis (1)
Landström, Maréne (1)
University
Umeå University (1)
Uppsala University (1)
Language
English (1)
Year
2009 (1)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view