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- Pereira, Maria J., et al.
(author)
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A Case Report of Improved Metabolic Control After Conversion From Everolimus to Cyclosporin A : Role of Adipose Tissue Mechanisms?
- 2014
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In: Transplantation Proceedings. - : Elsevier BV. - 0041-1345 .- 1873-2623. ; 46:7, s. 2377-2380
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Journal article (peer-reviewed)abstract
- Background. New-onset diabetes after transplantation is associated with an increase in risk of graft failure, cardiovascular disease, and mortality. Therefore, it compromises the overall beneficial outcome of organ transplantation. Case Report. A patient with new-onset diabetes after renal transplantation showed glucose and lipid metabolism improvements after switching immunosuppressant from everolimus to cyclosporin A. A subcutaneous adipose tissue biopsy displayed changes in gene and protein expression that could contribute to the clinical improvement of hyperglycemia and dyslipidemia.
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