SwePub - search: id:"swepub:oai:DiVA.org:uu-365...

Enumeration	Reference	Cover	Find
1.	Karlsson, Johan, 1979-, et al. (author) Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments 2018 In: Annual Review Of Chemical And Biomolecular Engineering, Vol 9. - : ANNUAL REVIEWS. - 1947-5446. - 9780824352097 ; , s. 105-127 Book chapter (peer-reviewed)abstract Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic cancer treatments by facilitating targeted delivery to a desired site. The physical and chemical properties of polymers can be tuned to accomplish delivery across the multiple biological barriers required to reach diverse subsets of cells. The use of biodegradable polymers as nanocarriers is especially attractive, as these materials can be designed to break down in physiological conditions and engineered to exhibit triggered functionality when at a particular location or activated by an external source. We present how biodegradable polymers can be engineered as drug delivery systems to target the tumor microenvironment in multiple ways. These nanomedicines can target cancer cells directly, the blood vessels that supply the nutrients and oxygen that support tumor growth, and immune cells to promote anticancer immunotherapy.

Karlsson, Johan, 1979-, et al. (author)
Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments
2018
In: Annual Review Of Chemical And Biomolecular Engineering, Vol 9. - : ANNUAL REVIEWS. - 1947-5446. - 9780824352097 ; , s. 105-127
Book chapter (peer-reviewed)abstract
- Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic cancer treatments by facilitating targeted delivery to a desired site. The physical and chemical properties of polymers can be tuned to accomplish delivery across the multiple biological barriers required to reach diverse subsets of cells. The use of biodegradable polymers as nanocarriers is especially attractive, as these materials can be designed to break down in physiological conditions and engineered to exhibit triggered functionality when at a particular location or activated by an external source. We present how biodegradable polymers can be engineered as drug delivery systems to target the tumor microenvironment in multiple ways. These nanomedicines can target cancer cells directly, the blood vessels that supply the nutrients and oxygen that support tumor growth, and immune cells to promote anticancer immunotherapy.

Träfflista för sökning "id:"swepub:oai:DiVA.org:uu-365869" "