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- Preece, Paul, et al.
(författare)
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Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease
- 2003
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Ingår i: Brain Research. Molecular Brain Research. - 0169-328X .- 1872-6941. ; 116:1-2, s. 155-158
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Tidskriftsartikel (refereegranskat)abstract
- Beta-secretase (BACE) and glycogen synthase kinase (GSK 3) are two enzymes thought to play a role in Alzheimer's disease. We extracted mRNA from 90 Alzheimer and 81 control brains. Levels of mRNA were quantified for BACE and GSK 3 with TaqMan real-time RT-PCR. We found no change in the Alzheimer's disease brains relative to controls for either the BACE or the GSK 3alpha mRNA levels.
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