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  • Rexhepaj, Elton, et al. (author)
  • Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer.
  • 2010
  • In: BMC cancer. - : Springer Science and Business Media LLC. - 1471-2407. ; 10
  • Journal article (peer-reviewed)abstract
    • Conflicting data exist regarding the prognostic and predictive impact of survivin (BIRC5) in breast cancer. We previously reported survivin cytoplasmic-to-nuclear ratio (CNR) as an independent prognostic indicator in breast cancer. Here, we validate survivin CNR in a separate and extended cohort. Furthermore, we present new data suggesting that a low CNR may predict outcome in tamoxifen-treated patients.
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