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- Attridge, Stephen, 1951, et al.
(författare)
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Detection of antibodies to toxin-coregulated pili in sera from cholera patients
- 2004
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Ingår i: Infect Immun. ; 72:3, s. 1824-7
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Tidskriftsartikel (refereegranskat)abstract
- Monoclonal antibodies (MAbs) were prepared against toxin-coregulated pili (TCP) isolated from Vibrio cholerae O1 El Tor. Despite their limited bactericidal potential, two MAbs were able to mediate biotype-specific protection against experimental cholera in infant mice. These MAbs were used in immunoblotting studies to assess seroconversion to El Tor TCP following cholera. Clear anti-pilus responses were observed in five of nine patients.
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