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  • Nilsson, Rune, et al. (author)
  • Different protein A immunosorbents may have different binding specificity for rat immunoglobulins
  • 1983
  • In: Journal of Immunological Methods. - 1872-7905. ; 62:2, s. 241-245
  • Journal article (peer-reviewed)abstract
    • Purified polyclonal immunoglobulin preparations representing the 4 rat IgG subclasses were tested for binding to Staphylococcus aureus protein A attached to 3 different solid phases (Staphylococcus aureus Cowan I bacteria, Sepharose CL4B and Sepharose 6MB). Protein A Sepharose CL4B showed higher reactivity with IgG1 and IgG2b than the staphylococci, whereas protein A Sepharose 6MB showed a lower uptake of these subclasses. No differences were seen for IgG2a and IgG2c. Protein A on different solid phases cannot be used interchangeably without confirmation of binding specificity.
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  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Kronvall, G (1)
Sjögren, H. O. (1)
Myhre, E (1)
Nilsson, Rune (1)
University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
1983 (1)

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