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Numrering	Referens	Omslagsbild	Hitta
1.	Wallman, Lars, et al. (författare) Robotic implementation of a microchip-based protein clean-up and enrichment system for MALDI-TOF MS readout 2006 Ingår i: Measurement Science & Technology. - 0957-0233. ; 17:12, s. 3147-3153 Tidskriftsartikel (refereegranskat)abstract A capillary filling microfluidic proteomic sample processing system has been realized in an automated set-up. Chip-integrated solid-phase extraction is performed in a 96-array format followed by sequential capillary action elution into a piezoelectric microdispenser and subsequent transfer to MALDI targets. Samples are eluted and deposited in volumes of 200–300 nl. The robotic system offers calibration to user-defined microextraction arrays and MALDI-target formats at micrometre resolution. Built-in force feedback control ensures a precise and robust microchip docking/handling in three dimensions. An efficient automated washing protocol eliminates analyte carry-over. System throughput ranges typically from 50–100 samples h-1.

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