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- Lindholm, C-E, et al.
(författare)
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Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results
- 1982
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Ingår i: Acta Radiologica: Oncology. - : Informa UK Limited. - 0349-652X. ; 21:4, s. 241-254
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Tidskriftsartikel (refereegranskat)abstract
- The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.
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