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  • Simonsson, Per, et al. (author)
  • Carbohydrate-deficient transferrin measured by high-performance liquid chromatography and CDTect immunoassay
  • 1996
  • In: Alcohol and Alcoholism. - 1464-3502. ; 31:4, s. 397-402
  • Journal article (peer-reviewed)abstract
    • Carbohydrate-deficient transferrin (CDT) was measured in three populations using anion-exchange chromatography followed by radioimmunoassay (CDTectTM) and a new high-performance liquid chromatography (HPLC) method. The correlation between the methods in 50 consecutive clinical samples was good (r = 0.87). However, in a set of 49 samples with CDT concentrations close to the reference value of the methods, the correlation was low (r = 0.51). In addition, among controls, no correlation between the methods was found (r = 0.10). Abnormal isoforms of transferrin were noted in 5% of the clinical samples. HPLC determination of CDT offers the advantage of identifying these isoforms of transferrin and thus reducing analytical pitfalls associated with the CDTectTM method.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Lindberg, S. (1)
Alling, Christer (1)
Simonsson, Per (1)
University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year

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