1. |
- Cowburn, AS, et al.
(author)
-
HIF isoforms in the skin differentially regulate systemic arterial pressure
- 2013
-
In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 1091-6490. ; 110:43, s. 17570-17575
-
Journal article (peer-reviewed)abstract
- The differential expression of the hypoxia-inducible factor-alpha (HIF-α) isoforms in the skin of mice influences vascular resistance and is correlated with homeostatic regulation of nitric oxide synthesis. A correlation between HIF isoform expression and hypertension was found in skin biopsies from human subjects, and may indicate a mechanism in the etiology of idiopathic hypertension.
|
|