↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "onr:"swepub:oai:DiVA.org:gih-6980" "

Search: onr:"swepub:oai:DiVA.org:gih-6980"

Result 1-1 of 1

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Motovylyak, Alice, et al. (author) Age-related differences in white matter microstructure measured by advanced diffusion MRI in healthy older adults at risk for Alzheimer’s disease 2022 In: Aging Brain. - : Elsevier. - 2589-9589. ; 2 Journal article (peer-reviewed)abstract Neurite orientation dispersion and density imaging (NODDI) is an advanced diffusion imaging technique, which can detect more distinct microstructural features compared to conventional Diffusion Tensor Imaging (DTI). NODDI allows the signal to be divided into multiple water compartments and derive measures for orientation dispersion index (ODI), neurite density index (NDI) and volume fraction of isotropic diffusion compartment (FISO). This study aimed to investigate which diffusion metric—fractional anisotropy (FA), mean diffusivity (MD), NDI, ODI, or FISO—is most influenced by aging and reflects cognitive function in a population of healthy older adults at risk for Alzheimer’s disease (AD). Age was significantly associated with all but one diffusion parameters and regions of interest. NDI and MD in the cingulate region adjacent to the cingulate cortex showed a significant association with a composite measure of Executive Function and was proven to partially mediate the relationship between aging and Executive Function decline. These results suggest that both DTI and NODDI parameters are sensitive to age-related differences in white matter regions vulnerable to aging, particularly among older adults at risk for AD.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-1 of 1

Refine your search

Type of publication: journal article (1)

Type of content: peer-reviewed (1)

Author/Editor: Hermann, Bruce P (1); Ma, Yue (1); Rowley, Howard A (1); Asthana, Sanjay (1); Bendlin, Barbara B (1); Johnson, Sterling C (1); show more...; Okonkwo, Ozioma C (1); Alexander, Andrew L (1); Sager, Mark A (1); Wang, Rui (1); Dean, Douglas C (1); Kecskemeti, Steven R (1); Gallagher, Catherine ... (1); Adluru, Nagesh (1); Motovylyak, Alice (1); Vogt, Nicholas M. (1); Oh, Jennifer M. (1); show less...

University: The Swedish School of Sport and Health Sciences (1); Karolinska Institutet (1)

Language: English (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

Year: 2022 (1)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view