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Numrering	Referens	Omslagsbild	Hitta
1.	Berntorp, Erik, et al. (författare) NovoSeven in warfarin-treated patients 2000 Ingår i: Blood Coagulation and Fibrinolysis. - 1473-5733. ; 11:Suppl 1, s. 113-115 Tidskriftsartikel (refereegranskat)abstract Haemorrhages represent a major complication of treatment with vitamin K antagonists. In cases of severe bleeding, a prompt effect on the increased International Normalized Ratio value is vital to achieve haemostasis. As conventional treatment, that is plasma or plasma-derived concentrates, carries the risk of blood-borne virus transmission, new treatments are needed. An open, multicentre pilot trial is currently under way to determine the effect of recombinant activated factor VII (rFVIIa; NovoSeven) administered to patients experiencing a bleeding episode after receiving vitamin K antagonists. When rFVIIa was given to a patient with a warfarin-induced nosebleed, it had an immediate haemostatic effect and the International Normalized Ratio value virtually normalized.

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