| 11. |
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| 12. |
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| 13. |
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| 14. |
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| 15. |
- Berg, M, et al.
(författare)
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A compact range telescope for K+ measurements
- 1996
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Ingår i: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. - 0168-9002. ; 381:2-3, s. 267-274
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Tidskriftsartikel (refereegranskat)abstract
- We present range telescopes for measurements of low energy K+ mesons together with first in-beam results. The hardware trigger, based on the observation of the mu(+) from the K+ --> mu(-) + nu(mu) decay channel, is designed for subthreshold hadron-nucleus
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| 16. |
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| 17. |
- Egholm, M., et al.
(författare)
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PNA HYBRIDIZES TO COMPLEMENTARY OLIGONUCLEOTIDES OBEYING THE WATSON-CRICK HYDROGEN-BONDING RULES
- 1993
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 365:6446, s. 566-568
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Tidskriftsartikel (refereegranskat)abstract
- DNA ANALOGUES are currently being intensely investigated owing to their potential as gene-targeted drugs1-3. Furthermore, their properties and interaction with DNA and RNA could provide a better understanding of the structural features of natural DNA that determine its unique chemical, biological and genetic properties3,4. We recently designed a DNA analogue, PNA, in which the backbone is structurally homomorphous with the deoxyribose backbone and consists of N-(2-aminoethyl)glycine units to which the nucleobases are attached5-9. We showed that PNA oligomers containing solely thymine and cytosine can hybridize to complementary oligonucleotides, presumably by forming Watson-Crick-Hoogsteen (PNA)2-DNA triplexes, which are much more stable than the corresponding DNA-DNA duplexes5-7, and bind to double-stranded DNA by strand displacement5,8. We report here that PNA containing all four natural nucleobases hybridizes to complementary oligonucleotides obeying the Watson-Crick base-pairing rules, and thus is a true DNA mimic in terms of base-pair recognition.
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| 18. |
- Elmer, R, et al.
(författare)
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K+ emission in symmetric heavy ion reactions at subthreshold energies
- 1996
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Ingår i: PHYSICAL REVIEW LETTERS. - : AMER INST PHYSICS. ; 77:24, s. 4884-4886
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Tidskriftsartikel (refereegranskat)abstract
- Subthreshold K+ production cross sections have been measured in symmetric Ne + NaF, Ni + Ni, and Au + Au collisions at 1.0A GeV. The mass dependence is strong, close to A(2). The angular distributions are nonisotropic in the center-of-mass system. Introdu
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| 19. |
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| 20. |
- Hammar, M. L., et al.
(författare)
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Effects of hormonal replacement therapy on the postural balance among postmenopausal women
- 1996
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Ingår i: Obstetrics and Gynecology. - 0029-7844 .- 1873-233X. ; 88:6, s. 955-960
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To establish whether hormone replacement therapy affects postural balance in postmenopausal women. METHODS: Nineteen healthy postmenopausal women with vasomotor symptoms were included. Median age was 54 years, median time since menopause was 3 years. They underwent dynamic posturography before and after 4 and 12 weeks of transdermal estrogen treatment (17 beta-estradiol 50 micrograms/day) as well as after 2 additional weeks of combined estrogen-progestagen treatment. The dynamic posturography method quantifies the amplitude, frequency, and pattern of body sway and tests the visual, vestibular, and somatosensory systems, which together maintain balance. The two most difficult tests either cancel visual and distort somatosensory inputs or give distorted information from both the visual and somatosensory systems. RESULTS: Hormone replacement therapy increased static balance performance assessed by dynamic posturography. A highly significant improvement was seen in the two most difficult tests between the pretreatment test and the test performed after 4 weeks of estrogen therapy (P < .01, P < .001, respectively). This improvement was sustained after 12 weeks and also during the 14th week, with the women on combined estrogen-progestagen treatment. CONCLUSION: Estrogen treatment increased balance performance measured by dynamic posturography, indicating that the beneficial effects from estrogens on postmenopausal fracture risk may include central nervous system effects on balance. Two weeks' addition of gestagen to the treatment regimen did not counteract the estrogen effects.
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