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Numrering	Referens	Omslagsbild	Hitta
11.	Clark, DW, et al. (författare) Associations of autozygosity with a broad range of human phenotypes 2019 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4957- Tidskriftsartikel (refereegranskat)abstract In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding.
12.	Day, FR, et al. (författare) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk 2017 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:6, s. 834- Tidskriftsartikel (refereegranskat)
13.	Linner, RK, et al. (författare) Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences 2019 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:2, s. 245- Tidskriftsartikel (refereegranskat)
14.	Ruderfer, DM, et al. (författare) Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes 2018 Ingår i: Cell. - : Elsevier BV. - 1097-4172 .- 0092-8674. ; 173:7, s. 1705- Tidskriftsartikel (refereegranskat)
15.	Winkler, TW, et al. (författare) Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2016 Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 12:6, s. e1006166- Tidskriftsartikel (refereegranskat)
16.	Winkler, TW, et al. (författare) The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2015 Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 11:10, s. e1005378- Tidskriftsartikel (refereegranskat)
17.	Demontis, D, et al. (författare) Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder 2019 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:1, s. 63- Tidskriftsartikel (refereegranskat)
18.	Fages, A., et al. (författare) Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series 2019 Ingår i: Cell. - : Elsevier BV. - 0092-8674. ; 177:6 Tidskriftsartikel (refereegranskat)abstract Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (>= 1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modem legacy of past equestrian civilisations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modem breeding impacted genetic diversity more dramatically than the previous millennia of human management.
19.	Grove, J, et al. (författare) Identification of common genetic risk variants for autism spectrum disorder 2019 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:3, s. 431- Tidskriftsartikel (refereegranskat)
20.	Jiang, X, et al. (författare) Publisher Correction: Shared heritability and functional enrichment across six solid cancers 2019 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4386- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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