| 11. |
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| 12. |
- Aydogdu, Özgu, 1978, et al.
(author)
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Predictors of surgical outcome in children with vesicoureteral reflux associated with paraureteral diverticula.
- 2010
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In: Urology. - : Elsevier BV. - 1527-9995 .- 0090-4295. ; 76:1, s. 209-14
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Journal article (peer-reviewed)abstract
- To retrospectively evaluate success rates of different surgical approaches in the treatment of paraureteral (Hutch) diverticula (PUD) associated with vesicoureteral reflux (VUR) and also to define preoperative objective criteria to predict the surgical outcome.Records of 51 patients who underwent surgical treatment for PUD were reviewed. Intravesical ureteroneocystostomy (UNC), subureteral injection, and extravesical UNC were performed in 23, 28, and 10 renal units, respectively. Records of patients were evaluated with particular emphasis on predictors of treatment outcome. Mean follow-up was 22.1 months (range, 3-46). Statistical significance was set at P <.05.Overall success rates were 91%, 79%, and 80% for intravesical UNC, subureteral injection, and extravesical UNC, respectively (P >.05). The mean PUD index for patients who underwent endoscopic treatment was significantly lower (P <.05). In the endoscopic group, reflux was detected at the late-filling or voiding phase of voiding cystourethrography (P <.005). In patients, who were diagnosed with video urodynamics, reflux began at higher bladder pressures and volumes in the injection group (P <.005). UNC was more frequently used in patients with the orifice at the neck or dome (P <.005).For injection in the lower PUD index, onset of reflux at late-filling or voiding phase on voiding cystourethrography, higher pressure and volume on video urodynamics, and C position orifice are positive predictive parameters for success. Bilateral reflux with high PUD index and grade 5 VUR are associated with failure of intravesical reimplantation. Presence of grade 5 VUR and an early onset of reflux outstand as negative predictive factors for unilateral extravesical UNC.
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| 13. |
- Aydogdu, Özgu, 1978, et al.
(author)
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Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy.
- 2011
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In: International braz j urol : official journal of the Brazilian Society of Urology. - 1677-6119. ; 37:3
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Journal article (peer-reviewed)abstract
- To evaluate the change in penile size r bilateral nerve sparing retropubic radical prostatectomy (BNSRRP) and possible effect of Tadalafil.A total of 65 patients underwent BNSRRP and they were evaluated prospectively for a whole year of follow-up. The patients were randomized to control without rehabilitation (Group 1) or Tadalafil rehabilitation group (Group 2). The patients were evaluated at months 3, 6 and 12 postoperatively for erectile function, penile measurements (flaccid penile length, penile length at maximum erection, penile circumference at flaccid status, and penile circumference at maximum erection), penile abnormalities and general health status. Statistical analysis was performed by Chi-Square test and significance was defined as p value < 0.05.In Group 1 there was significant decrease in penile measurements at month 3 compared to preoperative measurements. There was decrease in all parameters at month 6 compared to month 3 but only the decrease in penile length at maximum erection was significant. There were no significant differences between postoperative months 6 and 12 for all measurements. In Group 2 there was a tendency to decrease in all measurements at month 3 compared to baseline. There was no significant difference for penile measurements between postoperative 3rd and 6th months and between 6th month and the first year.Although further large sampled trials are needed to describe the possible positive effect of tadalafil or other PDE5-I 's on penile size after BNSRRP, tadalafil rehabilitation is effective in preserving penile size especially in the early postoperative period after BNSRRP.
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| 14. |
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| 15. |
- Aydogdu, Özgu, 1978
(author)
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Urinary stone disease and obesity: Different pathologies sharing common biochemical mechanisms.
- 2012
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In: World journal of nephrology. - : Baishideng Publishing Group Inc.. - 2220-6124. ; 1:1, s. 12-5
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Research review (peer-reviewed)abstract
- The prevalence of urolithiasis is increasing in parallel with the escalating rate of obesity worldwide. It has previously been speculated that obesity is a potential risk factor for urinary stone disease. The possibility that common biochemical mechanisms underlie both obesity and urolithiasis is remarkable. Better understanding of possible common mechanisms of these diseases could potentially lead to a better management of urinary stone prevention. The prevention of urinary stone formation gives clinicians an acceptable reason to encourage lifestyle modification and weight loss through a regular diet. In this review, the association of obesity with urinary stone disease, possible common biochemical mechanisms, effects of dietary habits and weight loss on stone formation, as well as difficulties in surgical management of obese individuals with urolithiasis are discussed.
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| 16. |
- Aydogdu, Özgu, 1978, et al.
(author)
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Urinary tract infection: Europe.
- 2011
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In: Guide to Pediatric Urology and Surgery in Clinical Practice. - 9781849963664 ; , s. 21-34
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Book chapter (other academic/artistic)
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| 17. |
- Burgu, Berk, et al.
(author)
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An unusual cause of infantile gynecomastia: sertoli cell tumor.
- 2011
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In: Journal of pediatric hematology/oncology. - 1536-3678. ; 33:3, s. 238-40
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Journal article (peer-reviewed)abstract
- Prepubertal testicular masses are relatively rare. Sertoli cell tumors account for 2% of prepubertal testicular tumors and very few have occurred in the first decade of life. Gynecomastia can be seen in approximately 5% of patients with testicular mass. We present an 8-month-old boy admitted with bilateral gynecomastia and unilateral testicular mass.
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| 18. |
- Burgu, Berk, et al.
(author)
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Both dorsal and ventral flaps can be used in previously circumcised hypospadic adults with comparable success rates.
- 2010
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In: International urology and nephrology. - : Springer Science and Business Media LLC. - 1573-2584 .- 0301-1623. ; 42:3, s. 689-95
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Journal article (peer-reviewed)abstract
- To compare dorsal and ventral dartos flap outcomes for tubularized incised-plate urethroplasty (TIPU) in terms of success, complication rates and cosmetic appearance in adult circumcised hypospadic men.Forty-two circumcised adult men underwent primary distal or midpenile hypospadias repair for cosmetic reasons by a single surgeon in a prospective randomized trial. Twenty-two patients were randomly selected for TIPU repair with dorsal (Group1, mean age 22.3 years) dartos flap as second layer. Twenty patients were randomly selected for TIPU repair with ventral dartos flap (Group2, mean age 21.1 years). Satisfaction questionnaires were answered by patients before surgery and at postoperative 6 weeks. The operating surgeon also filled in the form blindly at the same postoperative period. The differences between pre and postoperative satisfaction scores for each group were also evaluated. Preoperatively, all cases were evaluated with uroflowmetry and compared with postoperative results measured at 6th week of surgery. P < 0.05 was considered as significant.Mean follow-up was 24 months (4-28). Complications were encountered in 18 and 20% of the patients in groups 1 and 2, respectively. Complications were urethrocutaneous fistula, meatal stenosis, retrusive/proximal meatus and residual curvature. Success rates were 82 and 80%, respectively. No differences were seen in overall satisfaction between the two groups (P = 0.07).Outcome of hypospadias repair in circumcised adults for cosmetic reasons is similar to uncircumcised hypospadics previously mentioned in the literature. Both dorsal and ventral flaps can be used in previously circumcised hypospadic adults with comparable satisfaction and complication rates and uroflow findings.
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| 19. |
- Burgu, Berk, et al.
(author)
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Can the outcome of autoaugmentation omentocystoplasty be improved? Urodynamic, histological, and collagen content evaluation in sheep model.
- 2011
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In: Neurourology and urodynamics. - : Wiley. - 1520-6777 .- 0733-2467. ; 30:7, s. 1371-5
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Journal article (peer-reviewed)abstract
- To compare histological and urodynamic outcome of the classical detrusorotomy with and without the aid of intravesical balloon distension. We also describe a new technique with multiple detrusor incisions instead of detrusorotomy.A total of 24 animals were included in the study. Three different techniques of autoaugmentation cystoplasty were applied to surgically reduced bladders of 14 sheep. Five sheep underwent surgical reduction of bladder capacity as control group and five sheep underwent sham operation. In Group DIB (detrusor incision with balloon), standard whole thickness incisions on bladder wall were performed and a silicon balloon was inflated intravesically postoperatively. Group DMB (detrusorotomy with balloon) and Group DM (detrusorotomy) underwent standard detrusorotomy. After measuring capacities and compliances, animals were sacrificed on 90th postoperative day. Bladders were histopathologically evaluated. Expression of vascular endothelial growth factor (VEGF), CD31, and microvessel density (MVD) was noted. Quantification of collagen subtypes was also performed.The mean capacity and compliance for Group DM and control were not significantly different and both were lower than other augmentation groups and sham. In Groups DMB and DM fibrosis was significantly increased. The VEGF expression was lower in Group DIB with respect to other augmentation groups whereas MVD was not significantly different. Measurement of total collagen and collagen subtypes revealed an increase in total collagen of groups DMB and DM when compared to other groups. Quantification of collagen subtypes demonstrated that types I and III were significantly increased in aforementioned groups.Autoaugmentation omentocystoplasty in sheep model does not result in a reliable increase in bladder capacity and compliance. Intravesical balloon inflation makes the achievement more pronounced and significantly increases the bladder capacity and compliance.
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| 20. |
- Burgu, Berk, et al.
(author)
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Circumcision: pros and cons.
- 2010
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In: Indian journal of urology : IJU : journal of the Urological Society of India. - : Medknow. - 1998-3824. ; 26:1, s. 12-5
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Research review (peer-reviewed)abstract
- Circumcision is possibly the most frequently performed elective surgical procedure in men. It can simply be described as the excision of the preputium. There have been several studies about the association between circumcision and urinary tract infections (UTI). Many studies have demonstrated that the frequency of UTI increase in uncircumcised males, especially in the first year of life. This review discusses the embryology of the preputium, epidemiology, indications, complications and benefits of circumcision, as well as operation and anesthesiology techniques. It especially examines the association between UTI and circumcision and the importance of circumcision in congenital urinary system anomalies. In addition, this review examines the associations between circumcision and sexually transmitted diseases, including HIV, and the protective role of circumcision on penile cancer.
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